Advancing the Science

Mayo Clinic Medical Science Blog

May 3rd, 2016 · Leave a Comment

OLD DRUG OR NEW?

By Elizabeth Zimmermann Young elizabethzimmermann

Determining which drug works better for which patients

"Our findings definitely point toward important age-related risk that merits consideration when doctors are making treatment recommendations," says lead author Neena S. Abraham, M.D.

To the average TV viewer, it may seem like new drugs flood the marketplace daily.However, from the 1950s until just recently, warfarin was the only available anticoagulant drug approved by the Food and Drug Administration (FDA) to prevent blood clotting. One of the most common reasons people take an anticoagulant is to reduce stroke and heart attack risk related to atrial fibrillation, an irregular and often rapid heart rate that commonly causes poor blood flow. [...]

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Tags: anticoagulant, atrial fibrillation, dabigatran, Medical Research, Neena Abraham, rivaroxaban, warfarin

April 12th, 2016 · 2 Comments

A Head Start for HPV Vaccine: Better Series Completion

By meghanknoedler meghanknoedler

HPVHPV infographic

The Human Papillomavirus (HPV) is the most common sexually transmitted disease (STD), with about 14 million new cases each year.

Surprisingly, this STD is largely asymptomatic but can carry quite a punch.  HPV affects both men and women and can cause cervical cancer and other cancers of the genitals, anus, mouth, and throat, all of which can lead to severe disease, disability, infertility or death.

There are currently three different licensed vaccine options for use in girls and boys that protect against and prevent HPV, and using these vaccines routinely could potentially prevent 70% - 90% of cervical [...]

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Tags: HPV, Human Papillomavirus, Jennifer St Sauver, kern center, Lila Finney Rutten, REP, Robert Jacobson, Rochester Epidemiology Project, Science of health care delivery

March 31st, 2016 · Leave a Comment

Although Prostate-specific Antigen Screenings Now Result in Fewer Biopsies, Relative Risk of Complications has Increased

By Elizabeth Zimmermann Young elizabethzimmermann

mss_522405While absolute rates of biopsy and post-biopsy complications have decreased following several benchmark prostate-specific antigen (PSA) screening publications, the relative risk for each patient continues to increase, according to a new study by Mayo Clinic researchers.

The study is the largest to examine the impact of PSA screening trials and revised PSA screening guidelines on rates of prostate biopsy and the first to examine their impact on post-biopsy complications. The results, which appear in European Urology, suggest a need to reduce the harm associated with biopsy.

Read the full news release.

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Tags: Boris Gershman, Choose Wisely, Jeffrey Karnes, kern center, OtumLabs, Prostate Cancer, prostate cancer biopsy, prostate-specific antigen PSA, Science of health care delivery

March 30th, 2016 · Leave a Comment

New Deputy Director for Practice named — Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery

By Elizabeth Zimmermann Young elizabethzimmermann

dowdy2Sean C. Dowdy, M.D., has been appointed Deputy Director for Practice in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery.

Dr. Dowdy is also the Division Chair, Gynecologic Surgery within the Department of Obstetrics & Gynecology. He has a long track record of studying innovation and process improvements in the surgical environment.

Building on Mayo Clinic's more than 100 years of experience in applying scientific and engineering principles to health care delivery, the Kern Center for the Science of Health Care Delivery is transforming the way that patients everywhere receive and experience health care.

The center is highly focused [...]

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Tags: kern center, Science of health care delivery

March 15th, 2016 · Leave a Comment

New Treatment-Sequencing Based on Biomarker Elevation in Pancreatic Cancer

By meghanknoedler meghanknoedler

pancreasPancreatic cancer is the fourth leading cause of death in men and women and is projected to increase to the second leading cause of death by 2020 if there are not significant treatment advances made.

Our current understanding of pancreatic cancer suggests that it is a systemic disease in most patients, meaning, that by the time of usual diagnosis metastasis or spread of the cancer has already occurred, even if imaging studies are normal.  This aggressive nature of pancreatic cancer highlights the need for innovative treatment or diagnostic options for patients to improve survival.

truty

Mark Truty, M.D., Surgical Oncologist

A study done by [...]

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Tags: biomarkers, Elizabeth Habermann, kern center, Mark Truty, pancreatic cancer, treatment-sequencing, John Jay Bergquist

March 3rd, 2016 · Leave a Comment

Changes in Medical Education: Shifting Doctors' Attitudes in Medicine

By meghanknoedler meghanknoedler

Medical school training and admissions are going through many changes.  The medical school entrance exam (Medical College Admission Test or MCAT) is one of the notable changes.   For many years, the test focused on objective knowledge based on general chemistry and stoichiometry, organic chemistry.

compassionThe test made a drastic change in 2015 decreasing the questions regarding general chemistry, physics, biology and verbal skills.  In place of the more traditional questions, the test creators added questions in the domains of psychology and sociology.

This shift in the entrance exam reflects that it is becoming more important that clinicians are able to engage patients in empathic and collaborative ways.  It advances the notion that [...]

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Tags: Brian Lynch, kern center, Kern Scholars, Mayo Medical School, obesity, population health, Sean Phelan, unconscious bias

February 23rd, 2016 · Leave a Comment

Taking the First Step - Tracking Discharge Delays

By Elizabeth Zimmermann Young elizabethzimmermann

The national conversation continues to revolve around health care and improvements in health care delivery, and often focuses on finding ways to add value and reduce cost.

At Mayo Clinic, we too seek to enhance health and the way patients experience health care. Nurses are at the front line of patient care, and positioned such, we are able to understand problems and identify solutions from a unique perspective.

My colleagues and I have taken on one of these problems – discharge delays.dischargeplanning3136064_0001

Delayed hospital discharges is a prevalent topic in research literature (see PUBMED list) and have been a cause of concern for decades. However, true understanding and methods for [...]

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Tags: Diane Holland, discharge delays, Journal of Nursing Care Quality, nursing, nursing research, redcap, Science of health care delivery

February 19th, 2016 · Leave a Comment

Madonna Living Community Series Update: Clinomics – New Frontiers in Patient Care

By Elizabeth Zimmermann Young elizabethzimmermann

Mayo Clinic's three transformational centers - the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, the Center for Regenerative Medicine, and the Center for Individualized Medicine collaborate with the Madonna Living Community to offer a bi-monthly speaker series in which Mayo Clinic speakers share their research on topics relevant to both residents and the surrounding community.

Individualized Medicine ClinicOn Thursday, February 18, Dr. Eric Wieben spoke about Clinomics: New Frontiers in Patient Care to an audience at Madonna's Sister Generose Auditorium.

Dr. Wieben started his talk by defining clinomics as the study of –omics data along with its associated clinical data. He then focused on illustrating to the audience [...]

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Tags: clinomics, DNA, Eric Wieben, genome, Madonna Living Communities

February 16th, 2016 · Leave a Comment

Mayo Clinic to Host National Science of Team Science Conference

By Elizabeth Zimmermann Young elizabethzimmermann

Mayo Clinic is pleased to serve as the host institution for the 2016 Science of Team Science Conference.

With leadership from the National Institutes of Health (NIH) and a national planning committee, the conference will bring together scientists engaged in team-based research, institutional leaders who promote collaborative research, policy makers and federal agency representatives. The conference will take place May 16–19, 2016, at the Hyatt Regency hotel in Phoenix.

scits-logo

Abstracts are being sought for oral papers, lightning round presentations, panel presentations, and scientific posters. The deadline to submit abstracts is February 26.

Science of Team Science
The Science of [...]

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Tags: abstracts, Mayo Clinic research, Medical Research, National Institutes of Health, nih, SciTS, team science

February 9th, 2016 · Leave a Comment

Improving the State of the World: The Global Conversation on Health Care Delivery

By meghanknoedler meghanknoedler

Leaders from around the world converge annually to take part in global conversations at the World Economic Forum (WEF).  “Improving the state of the world,” lies at the heart of their mission, which they met to discuss in late January.world health

Notably, John Noseworthy, M.D., Mayo Clinic President and CEO, and, Sylvia Burwell, Department of Health and Human Services (DHHS) Secretary were both in attendance, championing health and health care delivery.  Also in attendance and contributing to the conversation were, other top private sector moguls and government officials including, Sheryl Sandberg, Chief Operating Officer of Facebook, Vice President of the United States, Joe Biden, and Canadian [...]

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Tags: health care delivery, Jeff Bolton, John Noseworthy, Jon Ebbert, Lindsey Philpot, payment reform, Rob Nesse, Sarah Meier, Science of health care delivery, Sylvia Burwell, Veronique Roger, World Economic Forum

February 5th, 2016 · Leave a Comment

Reducing patient wait time and improving staff satisfaction in the Emergency Department

By Elizabeth Zimmermann Young elizabethzimmermann

 ED-CELL_VT3409990v10-7Emergency Department Clinical Engineering Learning Laboratory: Engineering better experiences for Emergency Department patients, employees

“I saw 21 patients today, and it’s now 5 p.m. There are only seven in the waiting room, despite an afternoon that saw peak registrations of 21 per hour,” said Eric Boie, M.D., Emergency Medicine, one recent Monday evening. “I can’t help but think what this Monday would have looked like before [the Emergency Department Clinical Engineering Learning Laboratory]. Clearly ... [there would be] patients waiting and many leaving without being seen.”

Health Care Systems Engineering is one of the programs in the Mayo Clinic Robert D. and Patricia E. Kern Center for the [...]

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Tags: ED CELL, Emergency Department, health care systems engineering, kern center, learning laboratory, living lab, process improvement, Science of health care delivery, smart staffing

January 28th, 2016 · Leave a Comment

Pharmaceutical Pricing and Marketing: Markets vs. Regulation Seminar

By delivery delivery

The cost of medications is becoming a major threat to patients seeking treatment for disease, and the problem appears to be growing. What role a free market system and competition should play in a commercial area regulated by government regulation including patents is difficult to gauge. Patients and advocacy groups are calling for more awareness of the rising prices of important drugs for cancer and other life threatening conditions.

Mayo Clinic and Arizona State University have a strong and growing collaborative relationship surrounding the shared desire to improve health and the way patients experience health care. That collaboration most recently led to a seminar to address issues on pharmaceutical pricing and marketing, bringing together experts from across the [...]

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Tags: Arizona, cost of care, cost of health care, health care delivery, pharmacy, Rafael Fonseca

January 26th, 2016 · Leave a Comment

Resolutions for the New Year, HVHC 2.0

By meghanknoedler meghanknoedler

hvhc2It’s that time of year when we all make resolutions for the New Year.  We all strive to better ourselves: our mind, our body, our spirit.  Refocus and refresh.  Health care collaboratives seem to be no different, but rather than focusing on the individual, they are focused on bettering the lives of all patients.

Recently, the High Value Healthcare Collaborative (HVHC) repurposed the old and rang in the new HVHC 2.0. Founding member and current executive committee member Rob Nesse, M.D., says “it represents a return to our roots.”

Mayo Clinic, in conjunction with 17 other similar health care institutions across the country, including The Dartmouth Institute [...]

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Tags: high value health care, High Value Healthcare Collaborative, HVHC, Jim Naessens, Jon Ebbert, kern center, Lindsey Philpot, Nilay Shah, Rob Nesse

January 21st, 2016 · Leave a Comment

Educating the Now and Next Generations in Health Care Delivery

By delivery delivery

CSHCDThe New Year offers an opportunity to take stock of what we are doing to advance the science of health care delivery. In the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, one of the ways we do this is through education – both organic and collaborative programs.

We focus on integrating programs and opportunities to deliver training to current and future health care providers. We seek to equip health care providers with an understanding of the complex issues in the health care system today, and provide them the tools they need to fix it. Such education creates a knowledgeable team equipped to [...]

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Tags: continuing medical education, Education, healthcare delivery, kern center

January 19th, 2016 · 1 Comment

Mayo Clinic and Others Call Aging into the Limelight

By Megan Forliti mforliti

James Kirkland, M.D., Ph.D., Director of the Mayo Clinic Robert and Arlene Kogod Center on Aging

James Kirkland, M.D., Ph.D., Director of the Mayo Clinic Robert and Arlene Kogod Center on Aging

Aging: It’s a topic that impacts each and every one of us. It’s the single greatest risk factor for most chronic diseases, which account for the majority of morbidity and health care expenditures in developed nations. In a recently released book, “Aging: The Longevity Dividend,” experts in the field explore the topic and concurrent research in-depth and call for aging to be brought into the limelight.

Linda Partridge of the Max Planck [...]

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Tags: aging, Center on Aging, Dr James Kirkland, Kogod Center on Aging, research

January 5th, 2016 · 2 Comments

Did your patient have cardiac ablation? Don’t stop the anticoagulant!

By Elizabeth Zimmermann Young elizabethzimmermann

peter noseworthy

Peter Noseworthy, M.D., is a cardiac electrophysiologist at Mayo Clinic, and a Kern Health Care Delivery Scholar in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery.

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As a cardiac electrophysiologist, I am interested in helping to improve health and quality of life for my patients who see me because of an abnormal heart rhythm. The most common abnormal heart rhythm I treat is atrial fibrillation.

Although quite a few people – some 33 million worldwide – are diagnosed with atrial fibrillation (AF), many live their lives largely unaffected by the condition. AF does increase the [...]

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Tags: anticoagulant, atrial fibrillation, Optum Labs, OptumLabs, Peter Noseworthy, stroke

December 22nd, 2015 · Leave a Comment

Madonna Living Community Series Update: Collaborative care model for depression

By Elizabeth Zimmermann Young elizabethzimmermann

Ramona DeJesus, M.D.

Ramona DeJesus, M.D.

Mayo Clinic's three transformational centers - the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, the Center for Regenerative Medicine, and the Center for Individualized Medicine collaborate with the Madonna Living Community to offer a bi-monthly speaker series in which Mayo Clinic speakers share their research on topics relevant to both residents and the surrounding community.

On Thursday, December 17, Dr. Ramona DeJesus spoke about Depression Management in Primary Care: The Collaborative Care Model to an audience at Madonna's Sister Generose Auditorium.

She described a collaborative care model program, called Depression Improvement [...]

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Tags: collaborative care, depression, DIAMOND, EMERALD, Madonna Living Communities, primary care, Ramona DeJesus, kern center, Science of health care delivery

December 16th, 2015 · Leave a Comment

Minimally Invasive Surgery – Same Results, Less Complications, Disparity in Application

By Elizabeth Zimmermann Young elizabethzimmermann

Researchers find disturbing patterns of underuse for endometrial cancer patients.

Surgeons should use minimally invasive surgery to perform hysterectomy in women with non-metastatic endometrial cancer instead of the more risky open abdominal option. So why aren’t they?

This is the question that a collaborative team comprised of researchers from Mayo Clinic, Johns Hopkins and the University of California (Irvine and San Diego) is asking.

In a research paper published online ahead of print in Obstetrics & Gynecology, the team, led by senior author Sean Dowdy, M.D., Chair, Division of Gynecologic Surgery at Mayo Clinic, concluded that hospital utilization of minimally invasive surgery for the treatment of endometrial cancer varies considerably, [...]

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Tags: Endometrial cancer, hysterectomy, kern center, Mayo Clinic Cancer Center, minimally invasive surgery, MIS, quality measures, Science of health care delivery, Sean Dowdy, uterine cancer

December 8th, 2015 · 2 Comments

Healthcare Cost Concerns? Overtesting is part of the problem

By Elizabeth Zimmermann Young elizabethzimmermann

medical person with needle taking a blood drawIt’s not a new conversation – if you thought back over the last few weeks, you probably could remember at least one healthcare-related chat. Almost as likely, that conversation will have included mention of the cost, time, or other burden that you, or someone you know, have experienced.

The cost of healthcare continues to rise. At the same time, patients and caregivers are becoming more informed regarding their own healthcare concerns, and engaging in much more interactive decision-making with their providers regarding treatment options. If they don’t already, these conversations should include ensuring a mutual understanding of what tests are being ordered, and what the usefulness of the test(s) will be for care [...]

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Tags: Choosing Wisely, healthcare costs, kern center, Optum Labs, OptumLabs, overtesting, Rozalina McCoy, Science of health care delivery, Type 2 diabetes

December 1st, 2015 · Leave a Comment

Small School - National Influence - Right Tools

By Elizabeth Zimmermann Young elizabethzimmermann

ddp-right-tools-6colMayo Medical School is equipping students with the tools they will need to fix the nation's health care system.

Over the next two years, the school will establish a national footprint, expanding from a Minnesota campus into Arizona and Florida, and more than doubling its student body. At the same time, it will be transforming the traditional medical school curriculum, pairing the medical degree with a certificate in the Science of Health Care Delivery.

The challenges facing the country's health care system — from issues with access to rising costs — are considerable and complex. The science of health care delivery focuses on how patients actually receive care. From using engineering principles to determine the most [...]

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Tags: kern center, Mayo Medical School, Science of health care delivery

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