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Mayo Clinic Medical Science Blog

April 21st, 2015 · Leave a Comment

Mayo Clinic Designated as an AHRQ Evidence-based Practice Center

By Elizabeth Zimmermann Young

Continuing more than a century of health care delivery research and innovationEvidence Based Practice_smaller

In December, Mayo Clinic’s Evidence-Based Practice Research Program received a highly-competitive designation by the Agency for Healthcare Research and Quality (AHRQ), naming Mayo Clinic one of only 13 Evidence-based Practice Centers (EPCs) in North America.

The EPC program was launched in the 1990’s as an initiative of the U.S. Department of Health and Human Services. New or renewed selection as an EPC occurs every five years, and EPCs are charged with reviewing existing research and providing a summary of scientific evidence on designated topics. The goal of the program is to improve the effectiveness, appropriateness and overall quality of health care. EPCs seek to synthesize the available evidence and facilitate translation of evidence-based research findings.

Mayo Clinic’s Evidence-Based Practice Program intersects with both the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery and Mayo Clinic’s Knowledge and Evaluation Research Unit.


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Tags: AHRQ, evidence-based practice, Hassan Murad, KER unit, Kern center, meta analysis, Research, Science of health care delivery, systematic review, Victor Montori, Zhen Wang

April 17th, 2015 · Leave a Comment

Mayo Presence at Society of Behavioral Medicine Annual Meeting

By Elizabeth Zimmermann Young

Behavioral medicine is a multidisciplinary field that seeks to understand the way a person’s genetic makeup, behavior and surrounding environment interact to determine that person’s health and development of various illnesses. Understanding this interaction leads to discovery of ways to prevent and diagnose disease, or treat individuals – based on their unique story, and the way it mirrors that of the community they belong to.

You will find behavioral medicine experts across Mayo Clinic – many of them within the Robert D. Patricia E. Kern Center for the Science of Health Care Delivery. Next week, Lila Finney Rutten, Ph.D., the scientific director of the Population Health Science Program in the Kern Center, [...]

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Tags: Amenah Agunwamba, health care delivery, Jennifer St Sauver, Jon Ebbert, Kern center, Lila Rutten, Michelle van Ryn, population health, Robert Jacobson, Science of health care delivery, Scott Leischow, Shawna Ehlers, Society of Behavioral Medicine

April 14th, 2015 · Leave a Comment

Gathering at the Roundtable – Improving Population Health Through Multi-Sector Collaboration

By Elizabeth Zimmermann Young

The Institute of Medicine (IOM) of the National Academies undertakes a range of activities to convene leaders and experts from government, industry, academia, and public interest groups to inform policy and research. One IOM venue for convening diverse expertise around a topic of mutual interest is the IOM Roundtable. Roundtables are assembled by the IOM to generate discussion, movement, and knowledge sharing in areas of emerging significance in health. Like King Arthur’s round table of legend, members come together in a collegial fashion to combine strengths in pursuit of common goals.

In recognition of the interdependent environmental, social, economic, behavioral, genetic, and health care factors that determine health, the IOM established the Roundtable on Population Health Improvement in 2013.

Roundtable members envision the creation of an expanded multi-sector health system beyond traditional medical systems to improve quality of life, increase life expectancy, and promote health equality. The Roundtable aims to generate multi-sector discussions and collaborative efforts to improve population health and to disseminate knowledge about lessons learned and best practice in this space. Broadly, through a series of planned workshops, publications, and meetings, the Roundtable explores potential solutions to improve population health through: population-level interventions; modified reimbursement models; integration of primary care and public health; and engagement of community organizations in efforts to improve population health.


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Tags: community health, Institute of Medicine, Jennifer St Sauver, Kern center, Lila Rutten, National Academies, population health, Robert Jacobson, scholar program, Science of health care delivery

April 9th, 2015 · Leave a Comment

Deadline Approaching - Submit Abstracts Now for Delivery Science Summit 2015!

By Elizabeth Zimmermann Young

You are invited to submit an abstract now for Delivery Science Summit 2015. The submission deadline is April 27, 2015.

Hosted by the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, the conference will be held at the Mayo Civic Center, Sept. 16-18, 2015, in Rochester, Minnesota.

It will feature a poster session for presentation of original research across the following thematic areas:

  • Enhance Patient Experience
  • Improve Population Health
  • Manage Total Cost of Care

Projects that pertain to research and/or practice of health care delivery are welcome. They may include guidelines, randomized trials, outcome studies, practice innovations, modeling methods, policy [...]

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Tags: abstracts, conference, Delivery Science Summit, health care delivery, Kern center, Science of health care delivery

April 7th, 2015 · Leave a Comment

On Being a Kern Scholar in the Center for the Science of Health Care Delivery

By Elizabeth Zimmermann Young

Bellolio thumb


M. Fernanda Bellolio, M.D., is an Assistant Professor of Emergency Medicine at Mayo Clinic, and a Health Care Delivery Scholar in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery. 


I remember like yesterday when I received an e-mail from Drs. Jon Tilburt (@DrJonTilburt) and Erik Hess (@ErikHessMD) that I was accepted as a scholar in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery!  Wow.

I felt honored to be part of a select group of clinicians being trained and mentored in health services research to transform health care delivery and improve patient-centered outcomes. My friends asked, “Didn’t you already finish residency? What does being a scholar mean?”

group photo of Kern Scholars

As scholars we assess existing health care delivery systems and various care models, with the goal to improve those systems and improve the delivery of health care. Health services research harnesses the disciplines of the social sciences, including epidemiology, statistics and sociology, to providing evidence-informed and patient-centered health care.

The Kern Scholars Program brings together Mayo Clinic's strategic goals — to transform the health care delivery process by using our knowledge and information to provide solutions and remain trusted and affordable to patients and sustain a scholarly workforce relevant to recent health care reform legislation. [...]

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Tags: Fernanda Bellolio, health care delivery, Kern center, Kern Scholars, Optum Labs, Science of health care delivery

April 2nd, 2015 · Leave a Comment

Quest for Alzheimer’s Disease Treatments: Mitochondria Renders Clues

By Bob Nellis

Eugenia Trushina, Ph.D.

Eugenia Trushina, Ph.D.

A research group led by Mayo Clinic neuroscientist Eugenia Trushina, Ph.D, has investigated whether treatment with a small molecule CP2 can prevent the debilitating effects of Alzheimer’s disease  in three animal models of familial Alzheimer's, an inherited neurodegenerative disorder with symptoms of progressive cognitive decline in aging populations.

There is no cure for Alzheimer's in humans, and with no treatment aimed to prevent or stem the disease, it is estimated that 100 million people might suffer from Alzheimer's by 2050.

Dr. Trushina and her colleagues have shown that, by mildly inhibiting mitochondrial complex I with CP2, they reduce the levels of the biomarkers amyloid [...]

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Tags: AD, Alzheimer's, Alzheimer's disease, Eugenia Trushina, neuroscience

April 1st, 2015 · Leave a Comment

Individualized Medicine's Latest Computational Consortium

By Bob Nellis

Mayo Clinic's Center for Individualized Medicine -- with the University of Illinois at Urbana-Champaign and the University of Chicago -- is establishing a National Science Foundation Industry/University Collaborative Research Center called the Center for Computational Biotechnology and Genomic Medicine, or CCBGM. The goal is to study the applicability, timeliness, efficiency, and accuracy of the computational infrastructure that will address pressing genome-based challenges, through collaborative projects that include two or more of the member institutions. A key element of this NSF funding model is to recruit industry partners into the Center as a way to fund the research. The CCBGM recently hosted a planning meeting for university staff and representatives from 27 companies in primarily the biotech and computer [...]

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Tags: bioinformatics, Center for Individualized Medicine, computational genomics, genomics, medical genomics, Precision Medicine

March 31st, 2015 · Leave a Comment

Health Care Costs Rising? Consider onsite wellness center to reduce costs

By Elizabeth Zimmermann Young

exercisingA work site wellness center could be an important factor in controlling the costs of health care while encouraging healthy behavior says a Mayo Clinic study. Research published this month in the Journal of Occupational and Environmental Medicine showed cost savings averaging several thousand dollars per person visiting Mayo’s employee wellness center, as well notable reductions in weight and Body Mass Index (BMI). Check out the news release.


This research was conducted by researchers in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery. The center is committed to finding ways to enhance the patient's experience with [...]

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Tags: health care costs, Kern center, Science of health care delivery, wellness center

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