December 1st, 2016
With support from the state of Florida, Mayo Clinic's campus in Jacksonville, Florida, has opened a state-of-the-art laboratory for nanotechnology research, an emerging field of science that studies and applies materials that are the size of an atom.
The laboratory is a key part of Mayo Clinic's new Translational Nanomedicine Program. The goal is to develop, test and apply tiny materials in diagnosing and treating patients, particularly those with cancer.
Findings made in the lab will help expand and enhance cancer research, [...]
November 29th, 2016
Physicians are burned out.Â The reasons for which are seemingly endless: Â for one, the health care system is asking them to continually add more to their plate.Â More diagnosis codes, more communication and oversight with more complex patients, more administrative duties such as charting and patient emails and portal systems, yet no more time.
Physicians are expected to stay on top of ever-changing guidelines, and provide their patients effective, compassionate, high value care.Â More and more, reimbursement is tied to patient experience, but yet doctors have less time to actually spend WITH their patients ensuring the best possible experience.
Itâs a nasty spiral that is difficult to control.Â Then, add on the increasingly complex issue [...]
November 21st, 2016
InÂ recent months, we have heard a lot about physician burnout,Â medical student suicide, and other health care provider health and wellness issues. A growing problem, and one that is difficult to combat, as physician shortages are predicted to rise in the future, placing ever more burden on those in the system.
Shortages lead to issues accessing care. We worry about whether it will become more difficult for patients to access health care services, leading to poorer health outcomes. Before now, not much attention was paid to whether or not the doctors themselves had difficulty accessing care.
Little is known about the contribution to physician health of access to care. One might assume that for a medical doctor, care access is as simple as walking across the hall.
Unfortunately, nothing is that simple. [...]
November 17th, 2016
Bile duct cancer is an uncommon cancer that forms in the slender tubes (bile ducts) that carry digestive fluid through the liver. Bile duct cancer occurs mostly in people older than age 50. Symptoms include yellowing of the skin and eyes, intense itchiness of the skin, and white stools. Bile duct cancer is an aggressive type of cancer that progresses quickly and is difficult to treat.
Mayo Clinic Cancer Center researchers found that individuals who regularly used aspirin were significantly less likely to develop bile duct cancer.
"The evidence has been accumulating that regular, long-term [...]
November 15th, 2016
The Sangre Por Salud (Spanish for Blood for Health) Biobank was created to expand precision medicine research to underrepresented Latino patients in order to enhance the diversity of the Mayo Clinic Biobank. The biobank enables researchers to examine biological samples and data collected from Latino patients in order to develop better prevention, diagnostic tools and treatments for health issues specific to this group.
Mountain Park Health Center, a [...]
Tags: Arizona, Arizona State University, Biobank, Center for Individualized Medicine, Eleanna De Filippis, genomic, Latino, Mayo Clinic biobank, Mountain Park Health Center, personalized medicine, precision medicine, Sangre Por Salud
November 10th, 2016
Precision medicine research is advancing rapidly. New discoveries in how genetic, biological and environmental factors influence health and disease are leading to the development of new diagnostic tools and individualized therapies for many conditions. For many health care providers, keeping abreast of new discoveries and applying them to patient care can be a challenge.
The American Society of Human Genetics (ASHG) andÂ Mayo Clinic Center for Individualized Medicine (CIM)Â are collaborating to bridge the genomics education gap for health care providers. The two organizations will facilitate the use of genomics in medicine through education programs for health professionals.
âGenetics and genomics are evolving rapidly and reshaping significant areas of the healthcare landscape and medical education,â says Joseph McInerney, executive vice president ASHG. [...]
November 8th, 2016
By Bob Nellis
âI have to tell you that the sheer intellectual joy of finding out how life works is really cool.â Â Â Â Â Â â the late Susan Lindquist, Ph.D., pioneering genetic scientist
This last line from Dr. Lindquistâs obituary in the Sunday New York Times struck meÂ as a timeless statement of enthusiasm and dedication. Dr. Lindquist graduated from Illinois and Harvard and went on to explain how genetic mechanisms work behind such conditions as Parkinsonâs and Alzheimerâs.
Just hours after reading the Times, I received the link to the new video about Mayoâs role in creating scientists like Dr. Lindquist. I was thinking of her words as I watched it.
I can assure you, the enthusiasm in this footage is not staged or [...]
November 7th, 2016
Mayo Clinic in Florida is building two suites dedicated to delivering the latest regenerative medicine technologies
Until recently, regenerative medicine has been relegated to the laboratory and clinical trials. Not anymore. Mayo Clinic in Florida is building two suites dedicated to delivering technologies that just a decade ago were unimaginable.
"Amazing things are happening here, with vast implications in neurodegenerative diseases, musculoskeletal conditions, heart, vascular and kidney disease," says Gianrico Farrugia, [...]
November 1st, 2016
Two knee replacement surgeries, one patient, zero signs of slowing down
Lou Myers says despite two knee replacement surgeries, Mayo Clinic surgeons and researchers in Florida got him back to the game he loves quicker thanks to a more painless procedure.
Myers benefited from research conducted within the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery.Â In Florida, the center team focuses on valueÂ projects â analyzing the value stream,Â identifying best practices, benchmarkingÂ and working towards practice alignment.
During the time between Myers'Â two surgeries, Florida surgeons and other caregivers collaborated with experts in the Kern Center for the Science of Health Care Delivery to reduce [...]
October 27th, 2016
If a woman takes oral contraceptives, it provides not only reduced risk of developing ovarian cancer, but also better outcomes if she does get this deadly cancer.
"Multiple studies from a variety of sources have indicated that oral contraceptives are associated with a reduced risk of ovarian cancer, one of the most deadly cancers in women," said Aminah Jatoi, M.D., an oncologist with the Mayo Clinic Cancer Center. "However, few studies have explored the connection between the pill and outcomes in patients who ultimately develop the disease."
This knowledge [...]
October 4th, 2016
Researchers are seeking ways to make prostate cancer biopsies safer.
While absolute rates of biopsy and post-biopsy complications have decreased after several benchmark prostate-specific antigen (PSA) screening publications, the relative risk for each patient continues to increase, according to a new study by Mayo Clinic researchers.
The study is the largest to examine the impact of PSA screening trials and revised PSA screening guidelines on rates of prostate biopsy and the first to examine their impact on post-biopsy complications. The results, published in the March 2016 issue of European Urology, suggest a need to reduce the harm associated with biopsy.
September 27th, 2016
Surgeons find short breaks prove valuable in providing best care
Perfecting a skill requires equal parts natural talent, dedication and practice. A concert violinist plays a single piece of music over and over. A major league pitcher hurls strikes across home plate until the stadium lights go out. And a surgeon spends day after day leaning over an operating table while maintaining mental focus on the patient.
For all three, this kind of physical exertion and repetition stresses the body, leaving it vulnerable to work-related injuries that, over time, can cut careers short. [...]
September 13th, 2016
Clinical trials are the mechanism through which new and promising therapies for safe, effective cancer treatment ultimately become available.Â Not only do trials help identify new or best-practice therapeutic treatment options, but the act of participating in a trial has been shown to actually improve survival.
One of the most promising areas of research to fight cancer involves immunotherapy -- the use of vaccines or viruses as anti-cancer agents.Â Immunotherapeutic approaches through the use of vaccines, stimulates the bodyâs own cells to identify and fight cancer cells, utilizing a similar mechanism of action as we do with common childhood vaccines including measles, mumps and rubella (MMR). Viral therapies introduce a virus into [...]
September 13th, 2016
By Sara Tiner
Crumbling infrastructure puts us at risk, especially if itâs our own internal, bony frame.
But patients dealing with thinning bone in hips and spine have a choice to make.
They can accept the inevitable slumping spine and eventual hip fracture with all its associated disability that is quite likely to occur, or roll the dice with complications from osteoporosis medications.
Dr. KhoslaÂ isÂ one of the top osteoporosis experts in the world and a past president of the American Society for [...]
September 8th, 2016
Makshita "Maks" Luthra is a Master of Public Health candidate specializing in Public Health Administration & Policy, a Graduate Research Assistant at the University of Minnesota, and an associate health services analystÂ in theÂ Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery.Â
Childhood obesity has more than doubled in children and quadrupled in adolescents in the past 30 years. It is often linked to unhealthy eating habits and sedentary lifestyle. Another significant factor associated with obesity in children and adolescents are âadverse childhood experiences,â or ACEs. ACEs are [...]
September 2nd, 2016
By Sara Tiner
But is the current survey deluge training us to ignore the ones that actually matter? Ask Ann Harris, associate director of Mayo Clinicâs Survey Research Center, and sheâll nod.
âNow everyone has a survey,â she says. âI think we've just over-surveyed people and our challenge coming up is how do we do this?â
Mayo Clinic sends thousands of surveys a year to patients.
They flow out over the internet of course, but also by phone and (snail) mail. But the surveys donât flow back in [...]
August 16th, 2016
10,000 people help answer a basic individualized medicine question
Nearly 1 out of every 3 American adults has high blood pressure. About 70 percent of them take medication for their condition, but only half have it under control. Why? The answer gets to the heart of individualized medicine: Because each person has a unique genetic makeup, everyone responds differently to drugs.
In recent years, individualized medicine, sometimes called precision medicine, has made headlines by predicting the possibility an individual may develop a specific disease [...]
August 10th, 2016
In 2012, Rochester Epidemiology Project (REP) co-directors Walter Rocca, M.D., Mayo Clinic; and Barbara Yawn, M.D., Olmsted Medical Center; and their colleagues, published a paper describing the generalizability of epidemiological findings from one population to others.
Their premise - health and health care information derived from the largely ethnically homogeneous population in Olmsted County, Minnesota, and more recently in the 27 counties that comprise the REP, can indeed impact our ability to provide better care â regionally, nationally and beyond.
âWe suffer from the Lake Wobegon effect,â laments Dr. Rocca. âPeople say, âah yes, Minnesota, the place where all women are strong, all men are good looking, all children are above average, and you have a lot of cornfields â but what could you possibly tell me about my much more diverse population?ââ [...]
August 4th, 2016
Informed consent made easier in pediatric emergency sedation
The science of health care delivery can be very exciting â sometimes offering a futuristic peak into the way things could be. Soon we may have an app that enables near instantaneous health data analysis and distillation, and brings individualized care suggestions to a providerâs fingertips. Crunching data from hundreds of thousands of patients, finding the ones that are most like the patient in front of the provider, adding in genetic information, personal preferences and more, and in a blink of an eye, giving information for the most efficient and effective care.
In the meantime, we do things a little more manually, but the end, results are similar. [...]
August 3rd, 2016
By Bob Nellis
The core group of Mayo Clinic researchers thatÂ moved their lab to the base camp at Mount Everest to study heart disease and aging are at it again, this time in Africa. Along with a party of nearly 35, they will be climbing Mt. Kilimanjaro, obtaining scientific data from the climbers along the way.
Led by Mayo physiologist Bruce Johnson, Ph.D. and joined by Amine Issa, Ph.D., Courtney Wheatley, Ph.D., and Jan Stepanek, M.D., among others, the group will monitor climbersâ heart rates, oxygen saturation, movement, energy expenditure, skin temperature and the quality of their sleep. Theyâll also conduct ultrasound scanning to determine differences in younger and older climbers as they react to the altitude.