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Mayo Clinic Medical Science Blog

November 13th, 2014 · Leave a Comment

Mayo Clinic Researchers Seek Solutions for Treatment Resistant Depression

By Bob Nellis

Editor’s note: The following post is by Susannah Tye, Ph.D., researcher in Mayo’s Department of Psychiatry and Psychology. She and her team will be presenting at the Society for Neuroscience meeting in Washington, D.C. next week.

Susannah Tye, Ph.D.

Susannah Tye, Ph.D.

An important issue in the treatment of depression is development of new and effective treatments for those patients that do not respond effectively to available antidepressant therapies. Such individuals are diagnosed with treatment resistant depression. Without effective treatment, these individuals can suffer for months or years limited or no relief from their symptoms. Researchers within the Mayo Clinic Depression Center are investigating the reasons why some patients do [...]

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Tags: depression, Mayo Clinic, psychiatry, Research, Rochester, Society for Neuroscience, Treatment resistant depression

October 23rd, 2014 · Leave a Comment

We Can Do More! Be an Advocate for Cancer Research Funding

By Nicole Brudos Ferrara

The post below was written by Toni Kay Mangskau, clinical trials referral coordinator at Mayo Clinic Cancer Center and an active volunteer for the American Cancer Society and the National Patient Advocate Foundation.

Three generations of womenSeptember 2014 was the 10th anniversary of the death of my brother-in-law, Bruce, from cancer. I carry close to my heart a family conversation about Bruce urgently looking for any clinical trial opportunities in the world so he could possibly have more time to live. Unfortunately, his health declined and he was hospitalized in intensive care. As I walked into his hospital room, Bruce was surrounded by his wife, mother and children. Except for the medical machines, there was a [...]

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Tags: advocacy, advocate, cancer, Cancer Research, Research

October 13th, 2014 · Leave a Comment

Mayo Physicians Appointed to Florida Alzheimer's Board

By Bob Nellis

Leonard Petrucell, Ph.D.

Leonard Petrucell, Ph.D.

Neill Graff-Radford, M.D.

Neill Graff-Radford, M.D.

Two Mayo Clinic in Jacksonville specialists in Alzheimer’s disease — neurologist Neill Graff-Radford, M.D., and molecular neuroscientist Leonard Petrucelli, Ph.D. — have been appointed to Florida’s Alzheimer’s Disease Research Grant Advisory Board.

The appointment was made on Oct. 3 by State Surgeon General John Armstrong, M.D., FACS, who is also the Florida Secretary of Health. The 11-member board is a component of the new Ed and Ethel Moore Alzheimer’s Disease Research Program that will assist in the effort to fund research leading to the [...]

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Tags: advisory board, Alzheimer's, Alzheimer's disease, Florida

October 8th, 2014 · Leave a Comment

Photon counting CT Scanner makes research debut

By Bob Nellis

image

Dr. Cynthia McCollough of Mayo Clinic and Dr. Thomas Flohr of Siemens.

The arrival of a new CT scanner at Mayo Clinic is not usually worthy of a ribbon cutting ceremony, but this isn't your ordinary scanner. Destined solely for research, the first photon-counting-detector-based spectral CT  to be put into service anywhere was recently delivered to Mayo's Radiology Research Division. Obtained through a grant from the National Institutes of Health, the machine provides spatial resolution and material discrimination sensitivity at much lower radiation doses than conventional scanners. Reducing radiation exposure wherever possible has been a major objective for Cynthia McCollough, Ph.D. (sharing the scissors duty here). While the photo counting scanner will [...]

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Tags: atherosclerosis, imaging, Mayo Clinic research, radiology, radiology research, Siemens

September 18th, 2014 · 1 Comment

Kidney cancer survivor joins Mayo experts to share the changing treatment of kidney cancer

By Bob Nellis


Cynthia Chauhan joins Winston Tan, M.D., and Al Copland, Ph.D., both from the Mayo Clinic in Florida, for our second blog post in a lengthy series about kidney cancer. Cynthia is a Mayo Clinic patient who is a kidney and breast cancer survivor, leader of a kidney cancer survivor group, and patient advocate. Cynthia would like to share her thoughts on clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer and the diagnosis that she received over 16 years ago.

Chauhan: ccRCC is an aggressive cancer which, with the exception of high dose IL2, a difficult treatment with efficacy in only seven percent of ccRCC patients, is only treatable not curable when it metastasizes. When kidney cancer kills, [...]

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Tags: Cynthia Chauhan, kidney cancer, Mayo Clinic in Florida, Winston Tan, Al Copland, MayoClinicFL

September 10th, 2014 · Leave a Comment

New Sickle Cell Disease Guidelines from the National Heart, Lung and Blood Institute

By Bob Nellis

A team of international experts including M. Hassan Murad, M.D., Mayo Clinic Preventive Medicine and Mayo Clinic Kern Center for the Science of Health Care Delivery, has published new clinical guidelines for treatment of sickle cell disease (SCD) in this week’s Journal of the American Medical Association. Sickle cell disease is an inherited blood disorder — a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout the body, resulting in anemia, infections and pain.

SCD affects nearly 100,000 people in the United States and is associated with many acute and chronic complications requiring immediate medical attention. While two strongly-recommended, effective therapies -- hydroxyurea and long-term blood transfusions -- have been available, they are underused.
[...]

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Tags: guidelines, JAMA, Research, sickle cell

September 10th, 2014 · Leave a Comment

Mayo Clinic and Karolinska Institutet Celebrate 20 years

By Bob Nellis

Karolinska

It's been two decades since researchers from Mayo began annual scientific meetings with their counterparts at Karolinska, which is one of the top medical universities in Europe and the world. Beginning with investigators studying  metabolism issues, the relationship grew to include educational exchanges, many other medical disciplines and even organizational and planning sessions. Upwards of 80 delegates are arriving from Stockholm for two days of seminars, presentations and group meetings this week in Rochester. Heading the delegation will be Karolinska's president and vice chancellor, Dr. Anders Hemsten.

Mayo and Karolinska find that they speak the same language - and I don't mean English. It's the ultimate interest in finding answers for [...]

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Tags: education, Karolinska institute, Mayo Clinic, partnerships, Research, Sweden

September 9th, 2014 · Leave a Comment

Four New Partner Organizations Join Optum Labs Research Collaborative

By Bob Nellis

Optum Labs Official Logo

Optum Labs, the collaborative research and innovation center co-founded by Optum and Mayo Clinic, announced the addition of four new partners committed to improving the quality and value of patient care. These new partner organizations, which represent a cross-section of health care stakeholders, are:

Optum Labs, with the largest, de-identified patient database in health care, is the first open, collaborative research and innovation center designed to accelerate health care innovation, leading to improved patient care and patient value. Read more…

Tags: Optum Labs, Research

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