Advancing The Science

Mayo Clinic Medical Science Blog

September 18th, 2014 · 1 Comment

Kidney cancer survivor joins Mayo experts to share the changing treatment of kidney cancer

By Bob Nellis


Cynthia Chauhan joins Winston Tan, M.D., and Al Copland, Ph.D., both from the Mayo Clinic in Florida, for our second blog post in a lengthy series about kidney cancer. Cynthia is a Mayo Clinic patient who is a kidney and breast cancer survivor, leader of a kidney cancer survivor group, and patient advocate. Cynthia would like to share her thoughts on clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer and the diagnosis that she received over 16 years ago.

Chauhan: ccRCC is an aggressive cancer which, with the exception of high dose IL2, a difficult treatment with efficacy in only seven percent of ccRCC patients, is only treatable not curable when it metastasizes. When kidney cancer kills, [...]

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Tags: Al Copeland, Cynthia Chauhan, kidney cancer, Mayo Clinic in Florida, Winston Tan

September 10th, 2014 · Leave a Comment

New Sickle Cell Disease Guidelines from the National Heart, Lung and Blood Institute

By Bob Nellis

A team of international experts including M. Hassan Murad, M.D., Mayo Clinic Preventive Medicine and Mayo Clinic Kern Center for the Science of Health Care Delivery, has published new clinical guidelines for treatment of sickle cell disease (SCD) in this week’s Journal of the American Medical Association. Sickle cell disease is an inherited blood disorder — a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout the body, resulting in anemia, infections and pain.

SCD affects nearly 100,000 people in the United States and is associated with many acute and chronic complications requiring immediate medical attention. While two strongly-recommended, effective therapies -- hydroxyurea and long-term blood transfusions -- have been available, they are underused.
[...]

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Tags: guidelines, JAMA, research, sickle cell

September 10th, 2014 · Leave a Comment

Mayo Clinic and Karolinska Institutet Celebrate 20 years

By Bob Nellis

Karolinska

It's been two decades since researchers from Mayo began annual scientific meetings with their counterparts at Karolinska, which is one of the top medical universities in Europe and the world. Beginning with investigators studying  metabolism issues, the relationship grew to include educational exchanges, many other medical disciplines and even organizational and planning sessions. Upwards of 80 delegates are arriving from Stockholm for two days of seminars, presentations and group meetings this week in Rochester. Heading the delegation will be Karolinska's president and vice chancellor, Dr. Anders Hemsten.

Mayo and Karolinska find that they speak the same language - and I don't mean English. It's the ultimate interest in finding answers for [...]

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Tags: education, Karolinska institute, Mayo Clinic, partnerships, research, Sweden

September 9th, 2014 · Leave a Comment

Four New Partner Organizations Join Optum Labs Research Collaborative

By Bob Nellis

Optum Labs Official Logo

Optum Labs, the collaborative research and innovation center co-founded by Optum and Mayo Clinic, announced the addition of four new partners committed to improving the quality and value of patient care. These new partner organizations, which represent a cross-section of health care stakeholders, are:

Optum Labs, with the largest, de-identified patient database in health care, is the first open, collaborative research and innovation center designed to accelerate health care innovation, leading to improved patient care and patient value. Read more…

Tags: Optum Labs, research

August 26th, 2014 · Leave a Comment

Michael Sarr, M.D. Honored by College of Surgeons

By Bob Nellis

Michael Sarr, M.D., surgeon and scientist

Michael Sarr, M.D., surgeon and scientist

Mayo Clinic gastroenterologic surgeon and scientist Michael Sarr, M.D., is being honored by the American College of Surgeons for his research contributions, surgical expertise and mentorship of the next generation of surgical leaders. The ACS Committee for the Forum on Fundamental Surgical Problems has dedicated the new volume of the Surgical Forum to Dr. Sarr in recognition of his contributions to the surgical profession.

Dr. Sarr’s research has included work on gut transplants and pancreatic and bariatric diseases. He has published more than 500 peer-reviewed articles, 300 abstracts and 100 book chapters. Dr. Sarr [...]

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Tags: American College of Surgeons, awards, honors, Michael Sarr, surgical research

August 18th, 2014 · Leave a Comment

Scientists As Caregivers

By Bob Nellis

Not long ago I had the pleasure of witnessing one of those not infrequent moments around here, when patients get together with caregivers to say thank you.

Patients and their families find different ways of doing this, from cards and letters to homemade gifts as well as hugs and shout outs on social media. And on the receiving end, the physicians and nurses and technicians certainly appreciate it. This situation was slightly different. The physician in charge of the woman’s case held the celebration, a very nice dinner, but of the majority of people that Stacy Erholtz thanked that evening, only a handful were physicians. In fact, most of the audience was not from the clinical areas. They were laboratory scientists. And yes, they [...]

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Tags: biomedical research, MD, measles virus, multiple myeloma, oncolytic virus, PhD, Stacy Erholtz, Stephen Russell

July 22nd, 2014 · Leave a Comment

Dr. Younkin Receives Lifetime Achievement Award

By Bob Nellis

Younkin_LifetimeAchievementAward_Presentation_Photo 1[2]

Presenting some new Alzheimer's discoveries wasn't the only high point for Mayo Clinic researchers in Copenhagen recently at the Alzheimer's Association International Conference. On July 14 Steven Younkin, M.D., Ph.D., was awarded the Khalid Iqbal Lifetime Achievement Award for his years of research on the disease.

Dr. Younkin is Professor of Neuroscience at Mayo Clinic’s campus in Jacksonville, Florida. Before being recruited to Mayo in 1995, he was professor of Pharmacology and Pathology at Case Western Reserve University. Then he began research focused on the role of the amyloid beta protein in Alzheimer’s disease. Dr. Younkin’s current research focuses on the complex genetics of Alzheimer’s, seeking to identify effective, disease-modifying therapeutic approaches.

Khalid Iqbal, Ph.D. cofounded [...]

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Tags: AAIC, Alzheimer's, Alzheimer's disease, Florida, Lifetime Achievement Award, Mayo Clinic, neuroscience, research, Steven Younkin

July 10th, 2014 · Leave a Comment

Using Systematic Reviews and Meta-Analysis in Patient Care

By Bob Nellis

 

M. Hassan Murad, M.D.

M. Hassan Murad, M.D.

A team of international experts led by a Mayo Clinic researcher has published in the Journal of the American Medical Association a guide for clinicians who are interested in using systematic reviews and meta-analysis in clinical decision making. This article is the latest in the well-known series of users’ guides to the medical literature that JAMA started publishing in the mid 1990s and is highly sought after by clinicians who want to learn and practice evidence based medicine. “When searching for evidence to answer a clinical question, it’s better to seek a systematic review, especially one that includes a meta-analysis,” [...]

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Tags: JAMA, Mayo Clinic, Mayo Clinic research, medical literature, meta analysis, peer reviewed publications

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