Advancing The Science

Mayo Clinic Medical Science Blog

Archive for December 22nd, 2011

Mayo Research Teams Highlighted in Science

Posted on December 22nd, 2011 by Admin

Science, the general research journal published by the American Association for the Advancement of Science (AAAS) has highlighted three Mayo Clinic research teams in its year-end issue, out today online. The editors chose Mayo's recently published discovery on ridding the body of scenesent cells and its impact on aging - Baker et al. Nature 2011 -- as one of the top ten international scientific breakthroughs of the year. This is a list that covers all of science, worldwide, not just medicine or life sciences. That kudo goes to the team led by Mayo researcher Jan van Deursen, Ph.D., who has long been working on the mechanisms of aging in mouse models. This story reached a wide audience a few weeks ago, including the front page of the NY Times.

Another Mayo team highlighted in this issue of Science is one led by Mayo virologist Roberto Cattaneo, Ph.D., whose paper explaining why measles spreads so rapidly, appeared in the same issue of Nature as the van Deursen findings. It received wide play in the international media. The Catteneo study appears in a perspective section. The piece, An Exit Strategy for Measles Virus, is by Vincent Racaniello of the Microbiology and Immunology Department at Columbia University. The findings show how only one person with the measles virus can easily infect up to 20 people.

In both cases the narrative does not directly mention the Mayo researchers, but cites them as the source of the main point of the article. The citations are clickable.

In yet a third section, called Breakthroughs: Areas to Watch, the authors highlight topics expected to provide some news in the coming year. And there, under Stem Cell Metabolism, we find the reference to the team of Mayo's Clifford Folmes, Ph.D, Andre Terzic, M.D., Ph.D. and their paper in Cell Metabolism.

All in all, a pretty good showing for Mayo Clinic fundamental research in America's top Science journal. Congratulations all.

The Outlook on Multiple Myeloma

Posted on December 22nd, 2011 by Admin

The December 15 issue of the journal Nature includes special “Outlook” section focusing on multiple myeloma. According to the National Cancer Institute, multiple myeloma or plasma cell myeloma is the second most common blood cancer in the United States accounting for about 1 percent of all cancers.  While rare, multiple myeloma is often a deadly disease. However, recent advancements in drug and stem cell therapies have improved survival rates and new strategies to identify monoclonal gammopathy of undetermined significance (MGUS), a precursor to multiple myeloma, promise even more effective treatment of the disease. Mayo Clinic experts Vincent Rajkumar, M.D., Keith Stuart, M.D. and Steven Zeldenrust, M.D. contributed to stories in the section.