“Getting the what in the what?” That’s going to be a problem if health care professionals are asking that question in the future. Many medical centers are finding that patients have allergies or will be put at considerable risk if given the wrong drug for their genetic makeup or even the standard dose of the right drug. Pharmacogenomic screening prior to prescribing medications will one day be a normal practice. It’s the mantra of giving the right dose of the right drug at the right time. One size, one standard pharmaceutical practice, does not fit all. Your genome can often provide the answer. At Mayo’s Individualizing Medicine Conference today, we’ve been hearing about how pharmacogeneomic screens are done at St. Jude Children’s Hospital (thanks Dr. Mary Relling) and how those results are immediately going into those patients’ electronic medical record.
The problem comes in if patients aren’t exposed to appropriate screens — or if they don’t have an EMR. With an EMR, any physician can see almost immediately through a genomic-drug alert in the record (at Mayo a red flag pops up) that a patient should not be given drug X. This avoids a trial and error system of letting the patient’s physiology reject the drug while exhibiting associated side-effects. We are used to hearing the slogan “There’s an app for that.” Well, soon we’ll be able to say “There’s a test for that” — before you take a drug, any drug. There’s relevance for you.