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Mayo Clinic Medical Science Blog

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March 20th, 2015 · Leave a Comment

Hope for reversing multiple sclerosis

By Bob Nellis

In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time. Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told. […]

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Tags: biomedical research, moses rodriguez, MS, multiple sclerosis, neurology, neurosciences


March 17th, 2015 · Leave a Comment

Would You Get Screened for Cancer if You Could Do It At the Mall Instead of at the Hospital?

By Jon Ebbert, M.D.

Chronic heartburn can cause esophageal cancer. But people who suffer from heartburn often don’t get screened for cancer, and the results can be deadly. Heartburn can lead to a condition called “Barrett’s esophagus.” Barrett’s esophagus is a strong, and only known, risk factor for cancer of the esophagus.   New research conducted in collaboration with […]

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Tags: Barrett's esophagus, cancer screening, Endoscopy, mobile research vehicle


March 12th, 2015 · Leave a Comment

Doubts Put to Rest for Hormone Replacement Therapy

By Jon Ebbert, M.D.

Doctors used to give their female patients hormone replacement therapy (HRT) after menopause believing that it had positive health benefits. However, data from a large clinical trial cast profound doubt on these benefits. So much so that clinicians were encouraged to only give it to patients for symptoms related to menopause (hot flashes). Many women stopped their HRT. Meanwhile, other […]

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Tags: Benkhadra, ENDO, Endocrinology, hormone replacement therapy, HRT, Kern center, Science of health care delivery, women's health


March 11th, 2015 · Leave a Comment

Diabetes and Minnesota Community Measurement

By Jon Ebbert, M.D.

Researchers and clinicians working with the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery have observed that patients with diabetes with good control of their disease had better clinical outcomes. In this study of 5,731 patients with diabetes, patients were evaluated to see how well their disease control was on three measures selected by […]

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Tags: diabetes, Kern center, Minnesota Community Measurement, MN Community Measurement


February 3rd, 2015 · 2 Comments

“One Size Fits All” Doesn’t Apply to Quality Improvement

By Elizabeth Zimmermann Young

In an era of rising health care costs, and continuing efforts to improve value for patients nationwide, we have seen the rise of a number of quality improvement and reporting efforts. In his study, published today in the Journal of the American Medical Association, David Etzioni, M.D., and his team, illustrated that seeking a standardized […]

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Tags: American College of Surgeons, improvement, Kern center, NSQIP, quality, surgical outcomes, value, health care delivery, Science of health care delivery


January 19th, 2015 · Leave a Comment

Rheumatoid Arthritis and Heart Disease: Understanding the Connection

By Bob Nellis

Physicians have long known that people with rheumatoid arthritis and other rheumatic conditions such as lupus are more likely to die at younger ages than are those without these conditions. Even with advances in treatment, the gap in life expectancy remains. No one knew why until 15 years ago. That’s when researchers at Mayo Clinic […]

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Tags: Cardiology, Discovery's Edge, Heart Disease, rheumatoid arthritis


January 15th, 2015 · Leave a Comment

A Line in the Sand – Mayo Clinic’s Role in Early Insulin Research

By Bob Nellis

Early in the 20th century, a desperate group of patients began appearing at Mayo Clinic in the hope that the specialists there could keep them alive. Mostly children and younger adults, they had been afflicted with a condition that only years before would have been a death sentence — type I diabetes. Doctors at Mayo, […]

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Tags: diabetes, Endocrinology, history, Insulin, Mayo Clinic, medical history, Research


December 23rd, 2014 · Leave a Comment

What is Big Data, and Why Do We Care in Health Care?

By Bob Nellis

Big data is a term with uncertain roots, and variable usage, but one which paints a picture of extremely large amounts of information, complex and disparate, that is difficult to analyze using traditional tools. Other challenges with big data include collection and storage, sorting and searching, sharing and individual privacy – just because you have […]

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Tags: Big Data, Individualized Medicine, Mayo Clinic research, Science of health care delivery


December 15th, 2014 · Leave a Comment

Mayo Clinic Plugs Into Drug Discovery

By Bob Nellis

The research laboratory of Mayo Clinic pediatric oncologist Richard J. Bram, M.D., Ph.D., was enjoying the kind of success many researchers hope for. His team in Rochester, Minnesota, had long been interested in studying brain tumors, particularly those in children. “They’re the second most common malignancy in children, but the development of cures has lagged,” […]

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Tags: biomarkers, cancer, Center for Individualized Medicine, Mayo Clinic, Research


December 9th, 2014 · Leave a Comment

nuSURF Students Best Advocates for Science

By Bob Nellis

Summer Undergraduate Research Fellowships are awarded every year to deserving students who are interested in exploring specific topics in research. The goal, in addition to learning alongside professional medical researchers, is to determine if the students are truly interested in persuing research as a career. The students do everything a scientist does, including presenting findings […]

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Tags: Mayo Clinic, Research, science education, Summer Undergraduate Research Fellows, SURF