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Mayo Clinic Medical Science Blog

Findings

January 19th, 2017

Stereotactic radiosurgery is best for some brain tumors

By Elizabeth Zimmermann Young elizabethzimmermann

Shift in practice may reserve whole-brain radiation for patients with extensive disease. Patients with three or fewer metastatic brain tumors who received treatment with stereotactic radiosurgery (SRS) had less cognitive deterioration three months after treatment than did patients who received SRS combined with whole-brain radiation therapy. This finding is among the results of a federally […]

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Tags: brain tumor, Cancer, Mayo Clinic Cancer Center, Paul D Brown, stereotactic radiosurgery


January 9th, 2017

Single Allele Mutation Heightens Risk of Early-Onset Parkinson’s

By Bob Nellis bobnellis

A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic’s campus in Florida, found that a mutation in only one allele of a Parkinson’s gene, known as PINK1, increases the risk of early-onset disease. The finding, published recently in the journal Brain, addresses a longstanding debate about whether individuals need to […]

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Tags: Mayo Clinic research, neurology, Neurosciences, Parkinson's, Wolfdieter Springer


January 3rd, 2017

Integrating patient preferences in the delivery of Emergency Care. Kano analysis predicts change in experience.

By Elizabeth Zimmermann Young elizabethzimmermann

In our publication in Annals of Emergency Medicine, Pilot Study of Kano “Attractive Quality” Techniques to Identify Change in Emergency Department Patient Experience, we describe our efforts to improve our patient’s perception of receiving concern and sensitivity from their healthcare providers. The project originated in 2012, when our patients reported lower than expected ratings of […]

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Tags: Annals of Emergency Medicine, Emergency Medicine, Kano model, Venkatesh Bellamkonda


December 29th, 2016

Drug combo stems tumor growth in lung cancer

By Nicole Brudos Ferrara nicoleferrara

Researchers on Mayo Clinic’s campus in Jacksonville, Florida, have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent. The combination therapy worked in a laboratory study to stop lung adenocarcinoma associated with mutation of the KRAS gene. The study […]

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Tags: Alan Fields, auranofin, cancer stem cells, chemotherapy, Florida, KRAS gene, Lung Cancer, PKCiota, Forefront


December 22nd, 2016

Is there method in the madness: observation vs. full admission

By Elizabeth Zimmermann Young elizabethzimmermann

Last night a 68-year old male presented to the Emergency Department with chest pain. His pain lasted 45 minutes and resolved with 2 nitroglycerin tablets. He has history of coronary artery disease, stents placed within the past 2 years and a previous myocardial infarction. He has hypertension and diabetes. He was pain free by the […]

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Tags: AARP, Academic Emergency Medicine, chest pain, Emergency Medicine, Fernanda Bellolio, observation status, OptumLabs


December 15th, 2016

Combination therapy improves survival in adults with glioma

By Nicole Brudos Ferrara nicoleferrara

Radiation plus three-drug combo boosts progression-free survival and overall survival. Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than did patients who received radiation therapy alone. These are the results of […]

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Tags: brain cancer, cancer reseach, glioma, Jan Buckner, lomustine, PCV, procarbazine, radiation therapy, vincristine


December 13th, 2016

Nipple-sparing mastectomy may be a good option

By Elizabeth Zimmermann Young elizabethzimmermann

Technique offers a safe way to reduce breast cancer risk in carriers of the BRCA mutation. Mastectomies that preserve the nipple and surrounding skin prevent breast cancer as effectively as do more-invasive surgeries for women with a genetic mutation called BRCA, a multi-institution study led by Mayo Clinic Cancer Center found. The study findings were presented […]

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Tags: BRCA, Breast Cancer, Forefront, James Jakub, mastectomy, Mayo Clinic Cancer Center, nipple-sparing


December 7th, 2016

Sex- and age-related differences in parkinsonism

By Elizabeth Zimmermann Young elizabethzimmermann

Researchers at Mayo Clinic have found that drug-induced parkinsonism occurs more often in women than in men. It is also the most common type of parkinsonism among people younger than age 40. These findings, made possible by the Rochester Epidemiology Project, were published online in Movement Disorders. They give a different perspective from the team’s […]

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Tags: Epidemiology, medical research, Parkinson's, parkinsonism, REP, Rochester Epidemiology Project, Rodolfo Savica


December 6th, 2016

New strategies could make laryngectomies a thing of the past

By Elizabeth Zimmermann Young elizabethzimmermann

About 60,000 Americans have had their larynx removed due to disease or trauma. These people are missing out on many of life’s little pleasures because the procedure’s resultant hole left them without a voice and created an opening directly into their lungs. A simple shower is dangerous as even the slightest amount of water in […]

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Tags: Arizona, Center for Regenerative Medicine, David Lott, laryngectomy, medical research, regenerative medicine, stem cells


November 21st, 2016

Physician heal thyself

By Elizabeth Zimmermann Young elizabethzimmermann

In recent months, we have heard a lot about physician burnout, medical student suicide, and other health care provider health and wellness issues. A growing problem, and one that is difficult to combat, as physician shortages are predicted to rise in the future, placing ever more burden on those in the system. Shortages lead to issues accessing […]

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Tags: BMC Health Services Research, burnout, Hassan Murad, Philip Hagen, physician burnout, preventive medicine, kern center


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