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Mayo Clinic Medical Science Blog

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December 29th, 2016

Drug combo stems tumor growth in lung cancer

By Nicole Brudos Ferrara nicoleferrara

Researchers on Mayo Clinic’s campus in Jacksonville, Florida, have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent. The combination therapy worked in a laboratory study to stop lung adenocarcinoma associated with mutation of the KRAS gene. The study […]

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Tags: Alan Fields, auranofin, cancer stem cells, chemotherapy, Florida, KRAS gene, Lung Cancer, PKCiota, Forefront


December 22nd, 2016

Is there method in the madness: observation vs. full admission

By Elizabeth Zimmermann Young elizabethzimmermann

Last night a 68-year old male presented to the Emergency Department with chest pain. His pain lasted 45 minutes and resolved with 2 nitroglycerin tablets. He has history of coronary artery disease, stents placed within the past 2 years and a previous myocardial infarction. He has hypertension and diabetes. He was pain free by the […]

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Tags: AARP, Academic Emergency Medicine, chest pain, Emergency Medicine, Fernanda Bellolio, observation status, OptumLabs


December 15th, 2016

Combination therapy improves survival in adults with glioma

By Nicole Brudos Ferrara nicoleferrara

Radiation plus three-drug combo boosts progression-free survival and overall survival. Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than did patients who received radiation therapy alone. These are the results of […]

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Tags: brain cancer, cancer reseach, glioma, Jan Buckner, lomustine, PCV, procarbazine, radiation therapy, vincristine


December 13th, 2016

Nipple-sparing mastectomy may be a good option

By Elizabeth Zimmermann Young elizabethzimmermann

Technique offers a safe way to reduce breast cancer risk in carriers of the BRCA mutation. Mastectomies that preserve the nipple and surrounding skin prevent breast cancer as effectively as do more-invasive surgeries for women with a genetic mutation called BRCA, a multi-institution study led by Mayo Clinic Cancer Center found. The study findings were presented […]

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Tags: BRCA, Breast Cancer, Forefront, James Jakub, mastectomy, Mayo Clinic Cancer Center, nipple-sparing


December 7th, 2016

Sex- and age-related differences in parkinsonism

By Elizabeth Zimmermann Young elizabethzimmermann

Researchers at Mayo Clinic have found that drug-induced parkinsonism occurs more often in women than in men. It is also the most common type of parkinsonism among people younger than age 40. These findings, made possible by the Rochester Epidemiology Project, were published online in Movement Disorders. They give a different perspective from the team’s […]

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Tags: Epidemiology, medical research, Parkinson's, parkinsonism, REP, Rochester Epidemiology Project, Rodolfo Savica


December 6th, 2016

New strategies could make laryngectomies a thing of the past

By Elizabeth Zimmermann Young elizabethzimmermann

About 60,000 Americans have had their larynx removed due to disease or trauma. These people are missing out on many of life’s little pleasures because the procedure’s resultant hole left them without a voice and created an opening directly into their lungs. A simple shower is dangerous as even the slightest amount of water in […]

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Tags: Arizona, Center for Regenerative Medicine, David Lott, laryngectomy, medical research, regenerative medicine, stem cells


November 21st, 2016

Physician heal thyself

By Elizabeth Zimmermann Young elizabethzimmermann

In recent months, we have heard a lot about physician burnout, medical student suicide, and other health care provider health and wellness issues. A growing problem, and one that is difficult to combat, as physician shortages are predicted to rise in the future, placing ever more burden on those in the system. Shortages lead to issues accessing […]

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Tags: BMC Health Services Research, burnout, Hassan Murad, Philip Hagen, physician burnout, preventive medicine, kern center


November 17th, 2016

Aspirin use may help prevent bile duct cancer

By Elizabeth Zimmermann Young elizabethzimmermann

Bile duct cancer is an uncommon cancer that forms in the slender tubes (bile ducts) that carry digestive fluid through the liver. Bile duct cancer occurs mostly in people older than age 50. Symptoms include yellowing of the skin and eyes, intense itchiness of the skin, and white stools. Bile duct cancer is an aggressive […]

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Tags: bile duct cancer, Cancer, Lewis Roberts, Mayo Clinic Cancer Center


October 27th, 2016

“The Pill” associated with better ovarian cancer outcomes

By Elizabeth Zimmermann Young elizabethzimmermann

If a woman takes oral contraceptives, it provides not only reduced risk of developing ovarian cancer, but also better outcomes if she does get this deadly cancer. “Multiple studies from a variety of sources have indicated that oral contraceptives are associated with a reduced risk of ovarian cancer, one of the most deadly cancers in […]

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Tags: Aminah Jatoi, ovarian cancer, Mayo Clinic Cancer Center


October 4th, 2016

Prostate biopsies down, complications up

By Elizabeth Zimmermann Young elizabethzimmermann

Researchers are seeking ways to make prostate cancer biopsies safer. While absolute rates of biopsy and post-biopsy complications have decreased after several benchmark prostate-specific antigen (PSA) screening publications, the relative risk for each patient continues to increase, according to a new study by Mayo Clinic researchers. The study is the largest to examine the impact […]

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Tags: Jeffrey Karnes, kern center, Mayo Clinic Cancer Center, Optum Labs, OptumLabs, Prostate Cancer, prostate cancer biopsy, prostate-specific antigen PSA


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