Advancing the Science

Mayo Clinic Medical Science Blog

Findings Archive

January 15th, 2015 · Leave a Comment

A Line in the Sand – Mayo Clinic’s Role in Early Insulin Research

By Bob Nellis

Early in the 20th century, a desperate group of patients began appearing at Mayo Clinic in the hope that the specialists there could keep them alive. Mostly children and younger adults, they had been afflicted with a condition that only years before would have been a death sentence — type I diabetes. Doctors at Mayo, […]

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Tags: diabetes, Endocrinology, history, Insulin, Matthew Clark PhD, medical history, Research


December 23rd, 2014 · Leave a Comment

What is Big Data, and Why Do We Care in Health Care?

By Bob Nellis

Big data is a term with uncertain roots, and variable usage, but one which paints a picture of extremely large amounts of information, complex and disparate, that is difficult to analyze using traditional tools. Other challenges with big data include collection and storage, sorting and searching, sharing and individual privacy – just because you have […]

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Tags: Big Data, Individualized Medicine, Mayo Clinic research, Science of health care delivery


December 15th, 2014 · Leave a Comment

Mayo Clinic Plugs Into Drug Discovery

By Bob Nellis

The research laboratory of Mayo Clinic pediatric oncologist Richard J. Bram, M.D., Ph.D., was enjoying the kind of success many researchers hope for. His team in Rochester, Minnesota, had long been interested in studying brain tumors, particularly those in children. “They’re the second most common malignancy in children, but the development of cures has lagged,” […]

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Tags: biomarkers, cancer, Center for Individualized Medicine, Matthew Clark PhD, Research


December 9th, 2014 · Leave a Comment

nuSURF Students Best Advocates for Science

By Bob Nellis

Summer Undergraduate Research Fellowships are awarded every year to deserving students who are interested in exploring specific topics in research. The goal, in addition to learning alongside professional medical researchers, is to determine if the students are truly interested in persuing research as a career. The students do everything a scientist does, including presenting findings […]

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Tags: Matthew Clark PhD, Research, science education, Summer Undergraduate Research Fellows, SURF


December 4th, 2014 · Leave a Comment

Biomarker Discovery: Staying One Step Ahead of Cancer

By Bob Nellis

Four researchers at Mayo Clinic combined their talents to spur a “bedside to bench” movement that takes the issues they face in the clinic back to the laboratory in the hopes of discovering biomarkers to help specific patients facing difficult medical problems. George Vasmatzis, Ph.D., co-director of Mayo Clinic’s Biomarker Discovery Program in the Center […]

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Tags: biomarkers, cancer, Center for Individualized Medicine, Discovery's Edge, Research, Rochester


November 13th, 2014 · Leave a Comment

Mayo Clinic Researchers Seek Solutions for Treatment Resistant Depression

By Bob Nellis

Editor’s note: The following post is by Susannah Tye, Ph.D., researcher in Mayo’s Department of Psychiatry and Psychology. She and her team will be presenting at the Society for Neuroscience meeting in Washington, D.C. next week. An important issue in the treatment of depression is development of new and effective treatments for those patients that […]

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Tags: depression, Matthew Clark PhD, psychiatry, Research, Rochester, Society for Neuroscience, Treatment resistant depression


September 10th, 2014 · Leave a Comment

New Sickle Cell Disease Guidelines from the National Heart, Lung and Blood Institute

By Bob Nellis

A team of international experts including M. Hassan Murad, M.D., Mayo Clinic Preventive Medicine and Mayo Clinic Robert B. and Patricia E. Kern Center for the Science of Health Care Delivery, has published new clinical guidelines for treatment of sickle cell disease (SCD) in this week’s Journal of the American Medical Association. Sickle cell disease […]

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Tags: guidelines, JAMA, Research, sickle cell, Hassan Murad, Kern center


August 18th, 2014 · Leave a Comment

Scientists As Caregivers

By Bob Nellis

Not long ago I had the pleasure of witnessing one of those not infrequent moments around here, when patients get together with caregivers to say thank you. Patients and their families find different ways of doing this, from cards and letters to homemade gifts as well as hugs and shout outs on social media. And […]

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Tags: biomedical research, MD, Measles Virus, Multiple Myeloma, oncolytic virus, PhD, Stacy Erholtz, Stephen Russell


June 30th, 2014 · Leave a Comment

Mayo’s 22 in “Highly Cited Researchers”

By Bob Nellis

One of the factors in determining the impact a researcher has in the world of science is the number of times that papers by that individual are cited in other peer-reviewed articles. The assumption is that if a discovery is significant, more researchers will use it as a basis for advancing their own research and […]

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Tags: Highly Cited Researchers, Mayo Clinic research, peer reviewed publications, Thomson Reuters


April 29th, 2014 · Leave a Comment

Rochester Epidemiology Project: A Boon for Researchers and Patients

By Bob Nellis

   With its origins dating back to the early days of the Mayo Clinic, the Rochester Epidemiology Project is the medical resource behind discoveries that have affected patients around the globe. It’s been treasured by researchers and funded by the National Institutes of Health for nearly 50 years. Data collected from several generations of patients […]

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Tags: Epidemiology, Matthew Clark PhD, medical population studies, Medical Research, Olmsted County, Olmsted Medical Center, patient records, Research, Rochester Epidemiology Project