Advancing the Science

Mayo Clinic Medical Science Blog

Innovations Archive

March 20th, 2015 · Leave a Comment

Hope for reversing multiple sclerosis

By Bob Nellis Bob Nellis

In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time. Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told. […]

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Tags: Biomedical research, moses rodriguez, MS, multiple sclerosis, Neurology, neurosciences

March 17th, 2015 · Leave a Comment

Would You Get Screened for Cancer if You Could Do It At the Mall Instead of at the Hospital?

By Jon Ebbert, M.D. Jon Ebbert, M.D.

Chronic heartburn can cause esophageal cancer. But people who suffer from heartburn often don’t get screened for cancer, and the results can be deadly. Heartburn can lead to a condition called “Barrett’s esophagus.” Barrett’s esophagus is a strong, and only known, risk factor for cancer of the esophagus.   New research conducted in collaboration with […]

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Tags: Barrett's esophagus, cancer screening, Endoscopy, mobile research vehicle

January 19th, 2015 · Leave a Comment

Rheumatoid Arthritis and Heart Disease: Understanding the Connection

By Bob Nellis Bob Nellis

Physicians have long known that people with rheumatoid arthritis and other rheumatic conditions such as lupus are more likely to die at younger ages than are those without these conditions. Even with advances in treatment, the gap in life expectancy remains. No one knew why until 15 years ago. That’s when researchers at Mayo Clinic […]

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Tags: Cardiology, Discovery's Edge, Heart Disease, rheumatoid arthritis

January 16th, 2015 · Leave a Comment

Collaborating to Enhance Patient Experience

By Elizabeth Zimmermann Young Elizabeth Zimmermann Young

“The best interest of the patient is the only interest to be considered, and in order that the sick may have the benefit of advancing knowledge, union of forces is necessary. – Dr. William J. Mayo, 1910 The motivation behind Mayo Clinic’s many collaborative relationships is to improve patient care. These relationships are focused on finding […]

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Tags: Big Data, collaboration, Optum Labs, partnerships, kern center

January 15th, 2015 · Leave a Comment

A Line in the Sand – Mayo Clinic’s Role in Early Insulin Research

By Bob Nellis Bob Nellis

Early in the 20th century, a desperate group of patients began appearing at Mayo Clinic in the hope that the specialists there could keep them alive. Mostly children and younger adults, they had been afflicted with a condition that only years before would have been a death sentence — type I diabetes. Doctors at Mayo, […]

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Tags: diabetes, Endocrinology, history, Insulin, Matthew Clark PhD, medical history, Research

December 23rd, 2014 · Leave a Comment

What is Big Data, and Why Do We Care in Health Care?

By Bob Nellis Bob Nellis

Big data is a term with uncertain roots, and variable usage, but one which paints a picture of extremely large amounts of information, complex and disparate, that is difficult to analyze using traditional tools. Other challenges with big data include collection and storage, sorting and searching, sharing and individual privacy – just because you have […]

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Tags: Big Data, Individualized Medicine, Mayo Clinic research, Science of health care delivery

December 15th, 2014 · Leave a Comment

Mayo Clinic Plugs Into Drug Discovery

By Bob Nellis Bob Nellis

The research laboratory of Mayo Clinic pediatric oncologist Richard J. Bram, M.D., Ph.D., was enjoying the kind of success many researchers hope for. His team in Rochester, Minnesota, had long been interested in studying brain tumors, particularly those in children. “They’re the second most common malignancy in children, but the development of cures has lagged,” […]

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Tags: biomarkers, Cancer, center for individualized medicine, Matthew Clark PhD, Research

December 4th, 2014 · Leave a Comment

Biomarker Discovery: Staying One Step Ahead of Cancer

By Bob Nellis Bob Nellis

Four researchers at Mayo Clinic combined their talents to spur a “bedside to bench” movement that takes the issues they face in the clinic back to the laboratory in the hopes of discovering biomarkers to help specific patients facing difficult medical problems. George Vasmatzis, Ph.D., co-director of Mayo Clinic’s Biomarker Discovery Program in the Center […]

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Tags: biomarkers, Cancer, center for individualized medicine, Discovery's Edge, Research, Rochester

November 13th, 2014 · Leave a Comment

Mayo Clinic Researchers Seek Solutions for Treatment Resistant Depression

By Bob Nellis Bob Nellis

Editor’s note: The following post is by Susannah Tye, Ph.D., researcher in Mayo’s Department of Psychiatry and Psychology. She and her team will be presenting at the Society for Neuroscience meeting in Washington, D.C. next week. An important issue in the treatment of depression is development of new and effective treatments for those patients that […]

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Tags: Depression, Matthew Clark PhD, psychiatry, Research, Rochester, Society for Neuroscience, Treatment resistant depression

October 8th, 2014 · 1 Comment

Photon counting CT Scanner makes research debut

By Bob Nellis Bob Nellis

The arrival of a new CT scanner at Mayo Clinic is not usually worthy of a ribbon cutting ceremony, but this isn’t your ordinary scanner. Destined solely for research, the first photon-counting-detector-based spectral CT  to be put into service anywhere was recently delivered to Mayo’s Radiology Research Division. Obtained through a grant from the National […]

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Tags: atherosclerosis, imaging, Mayo Clinic research, Radiology, radiology research, Siemens