Advancing the Science

Mayo Clinic Medical Science Blog

Progress Updates Archive

March 20th, 2015 · Leave a Comment

Hope for reversing multiple sclerosis

By Bob Nellis

In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time. Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told. […]

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Tags: biomedical research, moses rodriguez, MS, multiple sclerosis, neurology, neurosciences


February 3rd, 2015 · 2 Comments

“One Size Fits All” Doesn’t Apply to Quality Improvement

By Elizabeth Zimmermann Young

In an era of rising health care costs, and continuing efforts to improve value for patients nationwide, we have seen the rise of a number of quality improvement and reporting efforts. In his study, published today in the Journal of the American Medical Association, David Etzioni, M.D., and his team, illustrated that seeking a standardized […]

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Tags: American College of Surgeons, improvement, kern center, NSQIP, quality, surgical outcomes, value, health care delivery, Science of health care delivery


January 19th, 2015 · Leave a Comment

Rheumatoid Arthritis and Heart Disease: Understanding the Connection

By Bob Nellis

Physicians have long known that people with rheumatoid arthritis and other rheumatic conditions such as lupus are more likely to die at younger ages than are those without these conditions. Even with advances in treatment, the gap in life expectancy remains. No one knew why until 15 years ago. That’s when researchers at Mayo Clinic […]

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Tags: Cardiology, Discovery's Edge, Heart Disease, rheumatoid arthritis


January 16th, 2015 · Leave a Comment

Collaborating to Enhance Patient Experience

By Elizabeth Zimmermann Young

“The best interest of the patient is the only interest to be considered, and in order that the sick may have the benefit of advancing knowledge, union of forces is necessary. – Dr. William J. Mayo, 1910 The motivation behind Mayo Clinic’s many collaborative relationships is to improve patient care. These relationships are focused on finding […]

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Tags: big data, collaboration, Optum Labs, partnerships, kern center


January 15th, 2015 · Leave a Comment

A Line in the Sand – Mayo Clinic’s Role in Early Insulin Research

By Bob Nellis

Early in the 20th century, a desperate group of patients began appearing at Mayo Clinic in the hope that the specialists there could keep them alive. Mostly children and younger adults, they had been afflicted with a condition that only years before would have been a death sentence — type I diabetes. Doctors at Mayo, […]

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Tags: diabetes, Endocrinology, history, Insulin, Matthew Clark PhD, medical history, Research


January 5th, 2015 · Leave a Comment

The Next Generation of Biomedical Researchers: Torn by Irresistible Forces

By Bob Nellis

Hours of study, lectures to attend, research to complete, labs to monitor, data to analyze, papers to write, new solutions to old problems to noodle on. It’s just another day in the life of a biomedical research student. The to-do list never seems to end. Morning to night, seven days a week.  The path to […]

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Tags: biomedical research, Matthew Clark PhD, Mayo Graduate School, research education


December 23rd, 2014 · Leave a Comment

What is Big Data, and Why Do We Care in Health Care?

By Bob Nellis

Big data is a term with uncertain roots, and variable usage, but one which paints a picture of extremely large amounts of information, complex and disparate, that is difficult to analyze using traditional tools. Other challenges with big data include collection and storage, sorting and searching, sharing and individual privacy – just because you have […]

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Tags: big data, Individualized Medicine, Mayo Clinic research, Science of health care delivery


December 15th, 2014 · Leave a Comment

Mayo Clinic Plugs Into Drug Discovery

By Bob Nellis

The research laboratory of Mayo Clinic pediatric oncologist Richard J. Bram, M.D., Ph.D., was enjoying the kind of success many researchers hope for. His team in Rochester, Minnesota, had long been interested in studying brain tumors, particularly those in children. “They’re the second most common malignancy in children, but the development of cures has lagged,” […]

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Tags: biomarkers, cancer, Center for Individualized Medicine, Matthew Clark PhD, Research


December 9th, 2014 · Leave a Comment

nuSURF Students Best Advocates for Science

By Bob Nellis

Summer Undergraduate Research Fellowships are awarded every year to deserving students who are interested in exploring specific topics in research. The goal, in addition to learning alongside professional medical researchers, is to determine if the students are truly interested in persuing research as a career. The students do everything a scientist does, including presenting findings […]

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Tags: Matthew Clark PhD, Research, science education, Summer Undergraduate Research Fellows, SURF


December 4th, 2014 · Leave a Comment

Biomarker Discovery: Staying One Step Ahead of Cancer

By Bob Nellis

Four researchers at Mayo Clinic combined their talents to spur a “bedside to bench” movement that takes the issues they face in the clinic back to the laboratory in the hopes of discovering biomarkers to help specific patients facing difficult medical problems. George Vasmatzis, Ph.D., co-director of Mayo Clinic’s Biomarker Discovery Program in the Center […]

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Tags: biomarkers, cancer, Center for Individualized Medicine, Discovery's Edge, Research, Rochester