Just learned that Yang Gao and Dr.¬†Steve Brimijoin of Mayo have the cover article in JPET this month: Transduction of cocaine hydrolase by striatal neurons and non-neural cells after local delivery of viral vector, page 449. This is a continuation of the work that was originally funded by the Minnesota Partnership for Biotechnology and Medical Genomics¬†in which they found an antidote to cocaine poisoning. In these new findings they report a much longer effect for their described approach - at least two months, with lesser effects for up to a year. Now the way is clear for behavioral studies to see if this can be useful in withdrawal in addition to toxicity treatment. Long-term outcome may be a cocaine vaccine.