Advancing the Science

Mayo Clinic Medical Science Blog

Bob Nellis (@bobnellis)

Activity by Bob Nellis

Bob Nellis (@bobnellis) posted · Tue, Apr 21 9:45am · View  

Richard Joseph, M.D., Named Doctor of the Year by Melanoma International Foundation

Richard Joseph, M.D.

Richard Joseph, M.D.

Richard Joseph, M.D., an oncologist specializing in melanoma at Mayo Clinic’s Florida campus, has been named the 2015 recipient of the “Doctor of the Year Award” presented by the Melanoma International Foundation (MIF). Founded in 2003, MIF is a non-profit organization whose vision is a future where top-notch melanoma treatment is accessible to all patients globally. Now in its tenth year, the annual award not only recognizes a physician involved in clinical research that is on the cutting edge of melanoma treatment, but who also exhibits a caring attitude towards his/her patients.

Dr. Joseph is actively involved in multiple leading edge clinical [...]

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Bob Nellis (@bobnellis) posted · Thu, Apr 2 4:07pm · View  

Quest for Alzheimer’s Disease Treatments: Mitochondria Renders Clues

Eugenia Trushina, Ph.D.

Eugenia Trushina, Ph.D.

A research group led by Mayo Clinic neuroscientist Eugenia Trushina, Ph.D, has investigated whether treatment with a small molecule CP2 can prevent the debilitating effects of Alzheimer’s disease  in three animal models of familial Alzheimer's, an inherited neurodegenerative disorder with symptoms of progressive cognitive decline in aging populations.

There is no cure for Alzheimer's in humans, and with no treatment aimed to prevent or stem the disease, it is estimated that 100 million people might suffer from Alzheimer's by 2050.

Dr. Trushina and her colleagues have shown that, by mildly inhibiting mitochondrial complex I with CP2, they reduce the levels of the biomarkers amyloid [...]

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Bob Nellis (@bobnellis) posted · Wed, Apr 1 8:29am · View  

Individualized Medicine's Latest Computational Consortium

Mayo Clinic's Center for Individualized Medicine -- with the University of Illinois at Urbana-Champaign and the University of Chicago -- is establishing a National Science Foundation Industry/University Collaborative Research Center called the Center for Computational Biotechnology and Genomic Medicine, or CCBGM. The goal is to study the applicability, timeliness, efficiency, and accuracy of the computational infrastructure that will address pressing genome-based challenges, through collaborative projects that include two or more of the member institutions. A key element of this NSF funding model is to recruit industry partners into the Center as a way to fund the research. The CCBGM recently hosted a planning meeting for university staff and representatives from 27 companies in primarily the biotech and computer [...]

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Bob Nellis (@bobnellis) posted · Fri, Mar 20 11:49am · View  

Hope for reversing multiple sclerosis

Dr. Moses Rodriguez

Dr. Moses Rodriguez

In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time.

Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told.

But Dr. Rodriguez wanted very much to be both a physician and researcher. As a physician he would specialize in identifying and treating neurologic problems, but then as a researcher, he would take those problems back to the lab where he would begin looking for solutions. Dr. Rodriguez has spent [...]

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Bob Nellis (@bobnellis) posted · Fri, Mar 13 2:39pm · View  

Dr. Edith Perez named to Board of AACR

Edith Perez, M.D.

Edith Perez, M.D.

Mayo Clinic physician and researcher Edith A. Perez, M.D. has been named to the Board of Directors of the American Association for Cancer Research. She is among five new members elected to serve on the AACR board for the 2015-2018 term and four members to serve on the nominating committee for the 2015-2017 term. They will begin their terms at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.  Dr. Perez is an internationally regarded breast cancer specialist and scientist based at Mayo Clinic's campus in Florida.

She  is deputy director at large at the Mayo [...]

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Elizabeth Zimmermann Young (@elizabethzimmermann) responded:

Congratulations!

Posted Fri, Mar 13 at 2:39pm CDT · View
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Bob Nellis (@bobnellis) posted · Fri, Feb 6 9:18am · View  

Dr. Mark Allen to head Society of Thoracic Surgeons

Mark Allen, M.D.

Mark Allen, M.D.

Mayo Clinic thoracic surgeon Mark S. Allen, M.D., has been elected president of The Society of Thoracic Surgeons during the society’s annual meeting in San Diego.

Dr. Allen is a professor of surgery at the Mayo Clinic College of Medicine. His research at Mayo includes serving as principal investigator for a study examining whether removing all lymph nodes in the chest is more effective than removing lymph nodes selectively in patients with stage I or stage II non-small cell lung cancer; the trial is supported by the National Cancer Institute and American College of Surgeons. [...]

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Bob Nellis (@bobnellis) posted · Mon, Jan 19 1:13pm · View  

Rheumatoid Arthritis and Heart Disease: Understanding the Connection

cardio-rheumPhysicians have long known that people with rheumatoid arthritis and other rheumatic conditions such as lupus are more likely to die at younger ages than are those without these conditions. Even with advances in treatment, the gap in life expectancy remains.

No one knew why until 15 years ago. That’s when researchers at Mayo Clinic helped establish that people with rheumatoid arthritis have a greater chance of developing various types of cardiovascular disease.

“We now know that rheumatoid arthritis is associated with an increased risk of heart and vascular disease,” says senior researcher Sherine E. Gabriel, M.D., a rheumatologist and epidemiologist in

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Bob Nellis (@bobnellis) posted · Thu, Jan 15 10:15am · View  

A Line in the Sand – Mayo Clinic’s Role in Early Insulin Research

Line_in_the_SandEarly in the 20th century, a desperate group of patients began appearing at Mayo Clinic in the hope that the specialists there could keep them alive. Mostly children and younger adults, they had been afflicted with a condition that only years before would have been a death sentence — type I diabetes.

Doctors at Mayo, led by endocrinologist and researcher Russell Wilder, M.D., and a handful of other centers across the country had found a drastic, but feasible method of saving many of them from this deadly disease. Dr. Wilder and his colleague, Walter Boothby, M.D., had formulated a special ketogenic diet.

Consisting of a precise proportion of carbohydrates, proteins and fats determined by [...]

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