Bob Nellis (@bobnellis)
Activity by Bob Nellis
In 1983, when Moses Rodriguez, M.D., established a small research lab to study multiple sclerosis (MS) at Mayo Clinic, he was told that he was wasting his time.
Dr. Rodriguez, now an emeritus staff member, was trained as a physician in neurology. Adding basic science research to his portfolio would be impossible, he was told.
But Dr. Rodriguez wanted very much to be both a physician and researcher. As a physician he would specialize in identifying and treating neurologic problems, but then as a researcher, he would take those problems back to the lab where he would begin looking for solutions. Dr. Rodriguez has spent [...]
Mayo Clinic physician and researcher Edith A. Perez, M.D. has been named to the Board of Directors of the American Association for Cancer Research. She is among five new members elected to serve on the AACR board for the 2015-2018 term and four members to serve on the nominating committee for the 2015-2017 term. They will begin their terms at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22. Dr. Perez is an internationally regarded breast cancer specialist and scientist based at Mayo Clinic's campus in Florida.
She is deputy director at large at the Mayo [...]
Dr. Allen is a professor of surgery at the Mayo Clinic College of Medicine. His research at Mayo includes serving as principal investigator for a study examining whether removing all lymph nodes in the chest is more effective than removing lymph nodes selectively in patients with stage I or stage II non-small cell lung cancer; the trial is supported by the National Cancer Institute and American College of Surgeons. [...]
Physicians have long known that people with rheumatoid arthritis and other rheumatic conditions such as lupus are more likely to die at younger ages than are those without these conditions. Even with advances in treatment, the gap in life expectancy remains.
No one knew why until 15 years ago. That’s when researchers at Mayo Clinic helped establish that people with rheumatoid arthritis have a greater chance of developing various types of cardiovascular disease.
“We now know that rheumatoid arthritis is associated with an increased risk of heart and vascular disease,” says senior researcher Sherine E. Gabriel, M.D., a rheumatologist and epidemiologist in
Early in the 20th century, a desperate group of patients began appearing at Mayo Clinic in the hope that the specialists there could keep them alive. Mostly children and younger adults, they had been afflicted with a condition that only years before would have been a death sentence — type I diabetes.
Doctors at Mayo, led by endocrinologist and researcher Russell Wilder, M.D., and a handful of other centers across the country had found a drastic, but feasible method of saving many of them from this deadly disease. Dr. Wilder and his colleague, Walter Boothby, M.D., had formulated a special ketogenic diet.
Consisting of a precise proportion of carbohydrates, proteins and fats determined by [...]
Hours of study, lectures to attend, research to complete, labs to monitor, data to analyze, papers to write, new solutions to old problems to noodle on. It’s just another day in the life of a biomedical research student. The to-do list never seems to end. Morning to night, seven days a week.
The path to becoming a biomedical researcher is not for the fainthearted. It requires years of study, an insatiable curiosity and unflagging persistence in the face of failure.
A Ph.D. candidate at Mayo Graduate School, Katherine A. Hartjes says traveling that long road has been worth it. She has [...]
Big data is a term with uncertain roots, and variable usage, but one which paints a picture of extremely large amounts of information, complex and disparate, that is difficult to analyze using traditional tools. Other challenges with big data include collection and storage, sorting and searching, sharing and individual privacy – just because you have massive amounts of information doesn’t mean you can use it effectively.
In an arena such as health care, where privacy concerns are paramount, and data collection is both disperse and diverse, it is not surprising that the challenges of using big data have – until recently – appeared to outweigh the benefits. However, as other industries [...]
The research laboratory of Mayo Clinic pediatric oncologist Richard J. Bram, M.D., Ph.D., was enjoying the kind of success many researchers hope for. His team in Rochester, Minnesota, had long been interested in studying brain tumors, particularly those in children.
“They’re the second most common malignancy in children, but the development of cures has lagged,” Dr. Bram says.
Dr. Bram’s research team made a big discovery: They found that a particular protein called cyclophilin B turned up in abundance in glioblastomas and medulloblastomas, two deadly nervous system tumors.
The protein seemed to be critical to these two cancers. “The findings suggested the protein could be a good target for a drug, selectively [...]