February 23rd, 2017
One of the highlights of the year for those of us at the Mayo Clinic Center for Individualized Medicine is the yearly Individualizing Medicine Conference. It’s a very exciting time for us as we share with you the latest discoveries in personalized patient care. This year’s conference already has a great line up of thought-provoking keynote speakers and innovative breakout sessions that offer ways to apply the latest advancement to the medical practice.
Experts in precision medicine from around the world will share how rapid advances in genomic technology and research are providing new insights into health and disease. How are these discoveries being turned into new [...]
February 21st, 2017
The struggle to lose weight is complex and full of challenges. For those who have struggled with their weight, finding hope and solutions can be difficult despite understanding the detrimental health consequences.
There is no question that losing weight is challenging. As a result, procedures exist that aim to remove fat cells from the body. A well-known procedure is liposuction, a surgical procedure which requires general anesthesia. In liposuction, fat cells are suctioned out through strategically-placed incisions. It carries with it a number of risks and side effects that range from cosmetic to life threatening. An emerging alternative to liposuction is Food and Drug Administration (FDA)-approved low-level laser therapy (LLLT); LLLT is more focused [...]
February 16th, 2017
Author Kevin Lin, Yale Daily News staff
Funded by a United States Food and Drug Administration grant of up to $6.7 million over two years, Yale and Mayo Clinic are establishing a Center of Excellence in Regulatory Science and Innovation to advance regulatory science by developing tools to measure the safety and efficacy of FDA-regulated products.
According to a press release, the Yale and Mayo Clinic CERSI aims to use real-world data to inform regulatory decision making; allow the FDA to use advanced analytic methods; and share knowledge gathered between the institutions. The Yale and Mayo Clinic CERSI is part of a larger group of national CERSIs, funded by the FDA, that are collaborations between the FDA and various [...]
February 16th, 2017
Drugs targeting the P13K-mTOR pathway add benefit when combined with standard R-CHOP therapy.
The drug everolimus can be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma, according to the results of a pilot study by Mayo Clinic researchers.
The researchers published their study findings in the July 2016 issue of The Lancet Haematology.
Patrick B. Johnston, M.D., [...]
February 15th, 2017
Nine Mayo Clinic employees will speak at the Healthcare Information and Management Systems Society (HIMSS) annual conference and exhibition in Orlando, Florida, Feb. 19-23.
Highlighting the Mayo presenters will be Mayo Clinic Chief Information Officer Christopher Ross, who will make the HIMSS preconference AsiaPac Summit keynote address The Role of Team-Based Care on the Path to Health Care Transformation.
Ross will also present on Emerging Impacts of Artificial Intelligence on Healthcare IT. That session, on Feb. 20, will explore how artificial intelligence and machine learning is changing health care and data collection and analysis, and how it can be used to address problems in patient care. The session also features James Golden, [...]
February 14th, 2017
What patients admitted from the Emergency Department to a general floor/ward will deteriorate?
Author Shawna Bellew, MD (@SBellzMD)
“That patient is going to trigger a rapid response team activation the minute they hit the floor.”
Whether said by a nurse, a resident, or the accepting physician, most emergency medicine physicians have heard some version of this statement.
Rapid response teams (RRTs), multidisciplinary groups of providers tasked with evaluating and managing patients with signs of impending deterioration, have become ubiquitous throughout the U.S. healthcare system, partially owing to their inclusion in the 2005 Institute for Healthcare Improvement’s “100,000 Lives Campaign.”
Recommendations for instituting these teams rest on the theory that early intervention can prevent further deterioration. Likewise, patients who trigger [...]
February 10th, 2017
By Bob Nellis
Two Mayo Clinic researchers have been named to the American Society for Clinical Investigation, bringing the total Mayo membership in the honorary society of physician-scientists to 39. Liewei Wang, M.D., Ph.D., a pharmacologist, and Martin Fernandez-Zapico, M.D., a pancreatic cancer biologist, were named to the society from several hundred nominees nationally. The society has 3,000 members.
Read the full news release on the Mayo Clinic News Network.
Learn about the American Society for Clinical Investigation.
February 9th, 2017
Why are you asking me this again? What does this have to do with my visit today? What does my doctor do with all these forms?
These questions, and others, led researchers in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery to consider the use of ‘smart,’ digital questionnaires delivered on an IPad in the waiting room, or via text or email to a patient’s preferred device or home computer before their appointment.
“Questionnaires are designed to collect what we call ‘patient [...]
February 5th, 2017
A team of Mayo Clinic researchers has identified evidence of bacteria in breast tissue and found differences between women with and without breast cancer.
These research findings were published in the August 3, 2016, issue of Scientific Reports.
"Our research found that breast tissue samples obtained in the operating room under sterile conditions contain bacterial DNA, even when there is no sign of infection," said Tina J. Hieken, M.D., a breast surgical oncologist at Mayo Clinic in Rochester, Minnesota. "Furthermore, we identified significant differences in the breast tissue microbiome of women with cancer versus women without cancer and the [...]
February 2nd, 2017
“In the last two decades, we’ve really burst onto the scene,” he says. “We’re engaged in exciting research not found elsewhere, and we offer the full spectrum of cardiac care — from fetal diagnosis through specialized treatment for children and adults with highly complex congenital conditions.”
Dr. Cetta points out several accomplishments:
February 1st, 2017
In a new article published in Nature Reviews Clinical Oncology, learn how Internet trends among oncology patients and those that care about them are changing. Co-authored by Lila Rutten, Ph.D., Robert D. and Patricia E. Kern Scientific Director for Population Health Science in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery and the National Cancer Institute’s Bradford Hesse, Ph.D., and Alexandra Greenberg, Ph.D., the article also discusses future trends, including examples of 'connected health' in oncology; diffusion of devices, sensors, and apps; the spread of personal data sharing; and an evolution in how networks can support person-centered care.
Read the abstract online on [...]
January 31st, 2017
Building the evidence base for best practice
Medical research has resulted in many amazing diagnostic and treatment methods, tools and drugs. Today a physician can look inside her patient’s body through the aid of radiation and iodine-based dyes in the blood stream – both of which could be deadly in another time or place. This same physician can then determine how well different organs are functioning and how clear blood vessels are.
However, this is not without risk. For example, in the case of patients with kidney disease, doctors need to use radioactive dyes to determine how well the kidneys are functioning. This information helps them decide what additional treatment (if any) is necessary. But the [...]
January 26th, 2017
In 2002, Giancarlo Logroscino, M.D., Ph.D., then a research scientist at the Sergievsky Center at Columbia University in New York City, published the only paper on the long-term prognosis of status epilepticus (SE) along with research collaborators from Columbia and Mayo Clinic. They established for the first time, in a rigorous investigation of SE in a population- based setting, the framework for data on frequency, classification and prognosis of the condition. SE is defined as continuous seizure of 30 minutes or more, or two or more seizures without full recovery of consciousness between them. Their work is published in journals including Neurology, European Journal of Neurology, Annals of Neurology and Archives of Neurology.
Tags: Dr Giancarlo Logroscino, Dr Jenny St Sauver, Dr Walter Rocca, Dr Wenjun Zhong, Mayo Clinic Alumni Magazine, population health, REP, Rochester Epidemiology Project, Science of health care delivery
January 24th, 2017
Sepsis is a potentially life-threatening complication of an infection. Typically, sepsis occurs in people who are already hospitalized, but is also diagnosed among patients who come to the emergency department. It is the most expensive condition treated in the U.S.
In 2002, the Society of Critical Care Medicine and the European Society of Intensive Care Medicine established the “Surviving Sepsis Campaign,” to reduce worldwide deaths from sepsis. The campaign seeks to build awareness of sepsis and educate health care providers regarding prevention, diagnosis and treatment. The group published guidelines and designed a performance improvement program, which are updated regularly. As with heart attacks and strokes, rapid identification and treatment of sepsis saves lives, but [...]
Tags: American Journal of Medical Quality, Emergency Department, Florida, kern center, Science of health care delivery, sepsis, Sepsis and Shock Response Team, Surviving Sepsis Campaign, Dr Pablo Moreno
January 19th, 2017
Shift in practice may reserve whole-brain radiation for patients with extensive disease.
Patients with three or fewer metastatic brain tumors who received treatment with stereotactic radiosurgery (SRS) had less cognitive deterioration three months after treatment than did patients who received SRS combined with whole-brain radiation therapy.
This finding is among the results of a federally funded Mayo Clinic-led multi-institution study whose results were published in the July 26, 2016, issue of JAMA.
"Metastatic brain tumors are, unfortunately, common in patients with cancer," said Paul D. Brown, M.D., a radiation oncologist at Mayo [...]
January 17th, 2017
Consensus group urges weighing pros, cons and patient preference in unilateral breast cancer.
A position paper issued by the American Society of Breast Surgeons recommends against contralateral prophylactic mastectomy (CPM) for average-risk women with breast cancer in only one breast.
The recommendation on prophylactic mastectomy, published online July 28, 2016, in the Annals of Surgical Oncology, addresses the growing trend to remove the healthy breast (contralateral prophylactic mastectomy) along with the breast with breast cancer.
"Contralateral prophylactic mastectomy is a growing trend that has generated significant discussion among physicians, patients, breast cancer [...]
January 12th, 2017
Over 100 researchers, clinicians, educators and administrators from across Mayo Clinic, as well as outside community members, gathered in Rochester, Minnesota, for the Office of Heath Disparities Research (OHDR) Annual Retreat in October. The meeting was a platform to share science updates, learn about study support and other resources, delve into health disparities topics and collaborate on future research projects and publications.
Keynote speaker Eliseo J. Pérez-Stable, M.D., director of the National Institute on Minority Health and Health Disparities (NIMHD), gave the talk “NIMHD’s Research Agenda to Improve the Health of Racial and Ethnic Minorities.”
Dr. Pérez-Stable made several key points about the NIMHD’s agenda:
January 10th, 2017
At the Mayo Clinic Cancer Center, hundreds of researchers dedicate their professional lives to reducing the burden of cancer. Each one has a unique story. In this issue, Jamie N. Bakkum-Gamez, M.D., a gynecologic oncologist at Mayo Clinic in Rochester, Minnesota, discusses her research.
January 9th, 2017
By Bob Nellis
A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic’s campus in Florida, found that a mutation in only one allele of a Parkinson’s gene, known as PINK1, increases the risk of early-onset disease. The finding, published recently in the journal Brain, addresses a longstanding debate about whether individuals need to inherit two copies of the mutation for an early form of the disease to occur.
The familial form of early-onset Parkinson’s, affecting patients as soon as age 45, is known to occur in individuals with mutations in both inherited alleles of the PINK1 (PTEN-induced putative kinase 1) gene. “This study showed [...]
January 5th, 2017
Updated guidelines make noninvasive colorectal cancer screening option available to millions.
The U.S. Preventive Services Task Force has issued its final colorectal cancer screening recommendations for 2016.
The task force assigns an overall "A" grade to colorectal cancer screening in people ages 50 to 75 and fully recommends several screening exams that now include Cologuard, the stool DNA test co-developed by Mayo Clinic and Exact Sciences Corp.
"The task force decision to include Cologuard will make this accurate and noninvasive new colorectal cancer screening option available to millions of people [...]