Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report [...]

Nine teams of Mayo Clinic employees pitched their ideas for health care innovations at the second annual Alligator Tank competition at the Mayo Clinic Florida campus on November 14, 2018.  Each team was given 120 seconds to explain their solution to a problem in the medical field before a live [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. How viruses hijack part of your immune system and use it against you An enzyme intended to [...]

This article originally appeared on the Center for Individualized Medicine blog on Oct. 10, 2018. The right diet, obesity and gut health are topics patients, clinicians and scientists wrestle with every day. We want to eat a good diet and lose weight or avoid weight gain, so our health span [...]

Millions of Americans have chronic kidney disease. Hundreds of thousands will progress to end stage kidney disease requiring either dialysis or kidney transplant. But research is underway to keep people from reaching that point. “Our goal is to take a look at how we can repair the diabetic kidney in terms [...]

This last summer, Stacy Erholtz celebrated another blessed event with her family. The oldest of her three children was married. "I never, never in my wildest dreams, thought I would be able to participate in that beautiful, joyful event," Stacy says as she wipes away tears that come easily whenever [...]

Courtney Krider was in eighth grade when she was first bit by the science bug. "That's when I started to take more diverse science classes that focused on chemistry and life sciences," she tells us. "I had a really good teacher and got to do a lot of cool labs, [...]

Not everyone in the United States speaks English as their first language. In fact, in 2013, the U.S. Census Bureau found that one of every five residents speaks another language at home. Unfortunately, this fact leads to another - for people with limited English proficiency, disparities are common in health [...]

Volunteering for a reading program at a children’s hospital led to a career change for Amy Lightner, M.D. As a Stanford University undergraduate, she met a cardiac surgeon who turned her interest to medicine. “I got to see how medicine and surgical intervention could change a child’s life forever,” says [...]

This article originally appeared on the Center for Individualized Medicine blog on Oct. 4, 2018 Article by Sharon Rosen   Lisa Schimmenti, M.D. has always been fascinated with Helen Keller and all she accomplished, in spite of being blind and deaf from a very young age. As the newly appointed [...]

By Martha Coventry, Senior Editor, University of Minnesota School of Public Health Program will train the next generation of researchers to work with clinicians, administrators, and patients in health care settings. A new collaboration among three of Minnesota’s most important health research, education, and care delivery organizations — University of [...]

By Ronna Campbell, M.D., Ph.D.;  Megan Motosue, M.D.; and M. Fernanda Bellolio, M.D.; Mayo Clinic Anaphylaxis is a serious, potentially life-threatening allergic reaction that affects millions of Americans. Today, nearly 15 million people in the U.S. have a food allergy and numbers are increasing. Symptoms of anaphylaxis can occur within seconds following [...]

Welcome to Advancing the Science. On Mayo Clinic's medical research blog we have a wide range of research and research-education content. In addition to stories you won't find anywhere else, we also collect content from other sources in one easy-to-access spot. The monthly Research News Roundup is one such aggregator, [...]

In 2017, Mayo Clinic launched a first-in-the-U.S. clinical test to help patients with some autoimmune disorders get the right diagnosis faster. The test defines a new form of inflammatory demyelinating disease, myelin oligodendrocyte glycoprotein (MOG) autoimmunity, which is distinct from multiple sclerosis (MS), with which it is commonly confused. The [...]

This article originally appeared on the Center for Individualized Medicine blog on Oct. 23, 2018. Mayo Clinic research is bringing together knowledge of psychiatry, genetics, metabolomics, pharmacogenomics and artificial intelligence to seek biological markers associated with alcohol use disorder and treatment response. Finding the molecular drivers of alcohol use disorder [...]

The Early Cancer Therapeutics Group at Mayo Clinic offers patients whose cancers haven't responded to standard chemotherapy or other treatments the opportunity to join an early-phase clinical trial of a potential new treatment. Early-phase clinical trials (phase I) determine safe dosage levels and safe methods of treatment delivery. A phase [...]

At the Mayo Clinic Cancer Center, hundreds of researchers dedicate their professional lives to reducing the burden of cancer. Each one has a unique story. In this video, Roxana S. Dronca, M.D., a hematologist and an oncologist at Mayo Clinic in Jacksonville, Florida, discusses her research on tumor immunology, malignant melanoma [...]

Rosa Rademakers, Ph.D., and Nilufer Ertekin-Taner, M.D., Ph.D., collaborate on Alzheimer’s disease-related research in the Department of Neuroscience at Mayo Clinic in Florida. Dr. Ertekin-Taner’s lab, which focuses on late-onset Alzheimer’s disease, generates large data sets of gene expression and multilevel genomics data that are shared with Dr. Rademakers’ lab, [...]

No? This is your chance! Forefront is the complimentary magazine of the Mayo Clinic Cancer Center. Published in online and email newsletter editions quarterly, Forefront highlights Mayo Clinic’s cutting-edge cancer research. The September 2018 edition of email/online Forefront features: A message from Mayo Clinic Cancer Center director, Robert Diasio, M.D. Article: Mayo Researchers a [...]

Discovering new, improved ways to meet unmet patient needs is why Mayo Clinic Research exists, and the teams in Orthopedic Biomechanics Laboratory and Sports Medicine Research are no exception. Director of both programs, Timothy Hewett, Ph.D., has conducted injury prevention research throughout his career. He published his first prospective study [...]

After decades of research, pharmacogenomics is “ready for prime time” so to speak. Mayo clinic is a leader in moving pharmacogenomics into clinical care — with the goal of helping providers identify medications that are compatible with their patients' genetic profiles. Drugs and Genes: Pharmacogenomics for the Modern Health Care [...]

Each year, more than one million women have biopsies that show non-cancerous changes in the breast, known as benign breast disease (BBD). Even though the changes may not require treatment, studies over the years at Mayo Clinic and elsewhere have found that not all cases of BBD are the same, [...]

This article originally appeared on the Center for Individualized Medicine blog on Oct. 15, 2018. Article by Sharon Rosen October is Breast Cancer Awareness Month, a time to reflect on new, individualized approaches to detecting and treating a cancer that affects 1 in 8 American women. Deborah Rhodes, M.D. and [...]

Although Mayo Clinic does not use genome editing as part of any treatment in the medical practice, genome editing has promise for treating and even curing previously intractable disorders, such as Duchenne muscular dystrophy. Genome editing, via methods like CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) can [...]

The Regenerative Medicine Therapeutic Suites has seen 1,000 patients since opening on Mayo Clinic’s Florida campus almost two years ago. The model, which integrated patient care with laboratory functions, is enabling the development and use of regenerative medicine products. The unique space serves both patients and clinicians, providing a place for multidisciplinary [...]