Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Feb 18, 2019

Head to the Lab for the Treatments of Tomorrow

By Sara Tiner @saratiner
Medical breakthroughs start in the lab with a phase of research called discovery science. It helps to understand how the body functions and how disease begins at the most basic level. That in turn provides insight into how whatever has gone wrong can be fixed. To kick off the medical [...]
Head to the Lab for the Treatments of Tomorrow
Feb 14, 2019

Using brain organoids to uncover causes of neuropsychiatric disorders

By Colette Gallagher @colettegallagher
Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these [...]
Using brain organoids to uncover causes of neuropsychiatric disorders
Feb 13, 2019

Coping with the "work of being a patient"

By Caitlin Doran @caityrosey
There’s no getting around it: being a patient is hard work. And it gets even harder for patients living with multiple chronic conditions. This “work” is made of up all the responsibilities and tasks doctors ask patients to take on in order to access and use health care and in [...]
Coping with the
Feb 12, 2019

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles @susanbuckles
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex [...]
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Feb 11, 2019

Zooming in on Colon Polyps

By Kate Ledger @k8ledger
Gastroenterologists agree that removing a colorectal polyp is an important step in preventing colon cancer, but one challenge has been excising polyps that are large, particularly those that are flat and more than an inch in diameter. A recently introduced minimally-invasive approach, called endoscopic mucosal resection, or EMR, facilitates the [...]
Zooming in on Colon Polyps
Feb 7, 2019

Eva Galanis, M.D.-Bitten by the virotherapy bug

By Advancing the Science contributor @advancingthescience
Every day more than 1,600 Americans die from cancer. Most of them have cancer that can’t be cured with traditional methods — surgery, radiation and chemotherapy. The father of Evanthia Galanis, M.D., was one of them. He died in the late 1990s from melanoma when his daughter was a junior faculty member at Mayo [...]
Eva Galanis, M.D.-Bitten by the virotherapy bug
Feb 6, 2019

Mayo Clinic investigators receive research awards from 'Regenerative Medicine Minnesota'

By Jennifer Schutz @jenniferschutz
Regenerative Medicine Minnesota (RMM) recently announced the 2019 Regenerative Medicine Minnesota Research Awards. This year's research grants are aimed at developing better therapies for people with diabetes, cartilage injury, heart disease, cancer, chronic obstructive pulmonary disease, spinal cord injury, neurological disorders, and age-related macular degeneration. The grants are awarded to [...]
Mayo Clinic investigators receive research awards from 'Regenerative Medicine Minnesota'
Feb 5, 2019

Research News Roundup-January 2019

By Elizabeth Zimmermann @elizabethzimmermann
The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Minnesota Partnership awards 5 collaborative research grants Diabetes, stress-induced aging and Alzheimer's disease, [...]
Research News Roundup-January 2019
Feb 4, 2019

"Only" a medical student, already advancing the science

By Jon Holten @jonholten
Rosalie Sterner is already impressive, concurrently pursuing her M.D. and Ph.D. degrees through Mayo Clinic College of Medicine and Science. However, recently she made additional waves, as the lone medical student to receive the 2018 Outstanding Abstract Achievement Award from the American Society of Hematology. Sterner received this award and [...]
Jan 31, 2019

New data gives clarity to allergy doctors and their patients

By Elizabeth Zimmermann @elizabethzimmermann
In a new study published in Mayo Clinic Proceedings, Mayo Clinic researchers present the first population-based evidence showing how often food allergies are diagnosed in people. The study also determined which foods are most likely to cause allergic reactions in different age groups. “There were no previous population-based estimates for [...]
New data gives clarity to allergy doctors and their patients
Jan 29, 2019

The Newbies Weigh In - Women in cardiology

By Advancing the Science contributor @advancingthescience
Diversity and inclusion are integral to Mayo Clinic's mission to provide excellent, culturally relevant care in a welcoming environment to patients from a wide variety of backgrounds and creating an inclusive work environment where differences are valued, allowing individuals to achieve and contribute to their fullest potential. The women featured [...]
The Newbies Weigh In - Women in cardiology
Jan 24, 2019

Golden era in medicine: Regenerative medicine symposium looks to the future

By Jennifer Schutz @jenniferschutz
Practice advancements, scientific discoveries, product development and access to care were just a few of the topics featured at the 2018 Mayo Clinic Symposium on Regenerative Medicine and Surgery, held earlier this month in Scottsdale, Ariz. Over 200 providers, scientists, educators, students, entrepreneurs and patient advocates were in attendance to share knowledge [...]
Golden era in medicine: Regenerative medicine symposium looks to the future
Jan 22, 2019

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Advancing the Science contributor @advancingthescience
By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who [...]
Pharmacogenomics: finding the right drug, dose for cancer therapy
Jan 17, 2019

RIGHT 10K: Blazing a trail to health care's future

By Susan Buckles @susanbuckles
Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic's Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn't involve running shoes but nevertheless is paving the way to [...]
RIGHT 10K: Blazing a trail to health care's future
Jan 15, 2019

A hard look at a devastating heart disease

By Kate Ledger @k8ledger
Though rare, cardiac sarcoidosis is a condition that can wreak havoc on the heart. It can be triggered by environmental or infectious agents and is characterized by an overactive immune response, involving clusters of white blood cells that aggregate in heart tissue. Those clusters can result in the need for [...]
A hard look at a devastating heart disease
Jan 14, 2019

New algorithms help predict diabetes treatment failure

By Advancing the Science contributor @advancingthescience
Metformin is the recommended first line treatment for type 2 diabetes, and is often used to prevent progression of prediabetes to diabetes. Unfortunately, it will not work for over one third of patients who take it, a condition called “therapeutic failure.” Historically there has been little way of knowing whether [...]
New algorithms help predict diabetes treatment failure
Jan 10, 2019

Gene therapy: potential and pitfalls

By Susan Buckles @susanbuckles
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food [...]
Gene therapy: potential and pitfalls
Jan 9, 2019

Why doctors might need to go back to 6th grade

By Elizabeth Zimmermann @elizabethzimmermann
When you leave the hospital, following an injury, stroke, surgery or other event, you are loaded down with paper. You receive instructions on how to take care of your body. They tell you how to prepare your home and your family. Other pages include directions on what medication to take, [...]
Why doctors might need to go back to 6th grade
Jan 8, 2019

Research News Roundup-December 2018

By Elizabeth Zimmermann @elizabethzimmermann
Each month, we publish Mayo Clinic's Research News Roundup. This post includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. December's news releases highlight some of the wide variety of research being [...]
Research News Roundup-December 2018
Jan 7, 2019

One more gift for you in the new year

By Elizabeth Zimmermann @elizabethzimmermann
Were you good last year? If so (or even if not - we don't judge) you might enjoy these little gifts of new knowledge, ideas, technology, and more from Mayo Clinic Research. Read on to learn about some of our newest research programs. Explore some of our shiniest websites (so [...]
One more gift for you in the new year
Jan 3, 2019

A vaccine to prevent breast cancer? It's worth a shot

By Advancing the Science contributor @advancingthescience
Each fall, millions of Americans roll up their sleeves for a flu shot, grateful for the quick pinch that may save them from the misery the flu can bring. In the not-too-distant future, there may be a poke with a much bigger payout. Scientists at Mayo Clinic and elsewhere are [...]
A vaccine to prevent breast cancer? It's worth a shot
Jan 2, 2019

Toward clinical trials for one type of ALS

By Kate Ledger @k8ledger
When a team of Mayo Clinic researchers discovered in 2011 the genetic repeat mutation known as c9orf72, the finding shed new light on amyotrophic lateral sclerosis (ALS). The mutation, which occurs as a short sequence of code repeated hundreds to thousands of times in the gene, is now known to [...]
Toward clinical trials for one type of ALS
Dec 27, 2018

Be the life [science] of the party

By Caitlin Doran @caityrosey
Looking for a scientific conversation starter for New Year's Eve? Advancing the Science has you covered with this top-10 recap of our hottest medical research stories from 2018. With this list in your back pocket, you'll never run out of interesting cocktail banter. And we guarantee you'll wow your friends [...]
Be the life [science] of the party
Dec 24, 2018

Our gift to you this holiday season

By Sara Tiner @saratiner
Your holiday gift list may include model planes or model rockets, but I hope it also includes the Mayo Model of Research. Haven’t you heard of it? It isn’t new but it is pretty amazing. It’s based around Mayo’s core value, the needs of the patient come first, as that [...]
Our gift to you this holiday season
Dec 21, 2018

MOG antibody-associated spinal cord inflammation can mimic acute flaccid myelitis

By Advancing the Science contributor @advancingthescience
Mayo Clinic researchers report that spinal cord inflammation associated with an antibody to myelin oligodendrocyte glycoprotein can mimic acute flaccid myelitis, a rare but serious disease linked to certain viruses that particularly affects children and can result in paralysis. The researchers show that detecting the MOG antibody has important treatment [...]
MOG antibody-associated spinal cord inflammation can mimic acute flaccid myelitis
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