By Martha Coventry, Senior Editor, University of Minnesota School of Public Health Program will train the next generation of researchers to work with clinicians, administrators, and patients in health care settings. A new collaboration among three of Minnesota’s most important health research, education, and care delivery organizations — University of [...]

By Ronna Campbell, M.D., Ph.D.;  Megan Motosue, M.D.; and M. Fernanda Bellolio, M.D.; Mayo Clinic Anaphylaxis is a serious, potentially life-threatening allergic reaction that affects millions of Americans. Today, nearly 15 million people in the U.S. have a food allergy and numbers are increasing. Symptoms of anaphylaxis can occur within seconds following [...]

Welcome to Advancing the Science. On Mayo Clinic's medical research blog we have a wide range of research and research-education content. In addition to stories you won't find anywhere else, we also collect content from other sources in one easy-to-access spot. The monthly Research News Roundup is one such aggregator, [...]

In 2017, Mayo Clinic launched a first-in-the-U.S. clinical test to help patients with some autoimmune disorders get the right diagnosis faster. The test defines a new form of inflammatory demyelinating disease, myelin oligodendrocyte glycoprotein (MOG) autoimmunity, which is distinct from multiple sclerosis (MS), with which it is commonly confused. The [...]

This article originally appeared on the Center for Individualized Medicine blog on Oct. 23, 2018. Mayo Clinic research is bringing together knowledge of psychiatry, genetics, metabolomics, pharmacogenomics and artificial intelligence to seek biological markers associated with alcohol use disorder and treatment response. Finding the molecular drivers of alcohol use disorder [...]

The Early Cancer Therapeutics Group at Mayo Clinic offers patients whose cancers haven't responded to standard chemotherapy or other treatments the opportunity to join an early-phase clinical trial of a potential new treatment. Early-phase clinical trials (phase I) determine safe dosage levels and safe methods of treatment delivery. A phase [...]

At the Mayo Clinic Cancer Center, hundreds of researchers dedicate their professional lives to reducing the burden of cancer. Each one has a unique story. In this video, Roxana S. Dronca, M.D., a hematologist and an oncologist at Mayo Clinic in Jacksonville, Florida, discusses her research on tumor immunology, malignant melanoma [...]

Rosa Rademakers, Ph.D., and Nilufer Ertekin-Taner, M.D., Ph.D., collaborate on Alzheimer’s disease-related research in the Department of Neuroscience at Mayo Clinic in Florida. Dr. Ertekin-Taner’s lab, which focuses on late-onset Alzheimer’s disease, generates large data sets of gene expression and multilevel genomics data that are shared with Dr. Rademakers’ lab, [...]

No? This is your chance! Forefront is the complimentary magazine of the Mayo Clinic Cancer Center. Published in online and email newsletter editions quarterly, Forefront highlights Mayo Clinic’s cutting-edge cancer research. The September 2018 edition of email/online Forefront features: A message from Mayo Clinic Cancer Center director, Robert Diasio, M.D. Article: Mayo Researchers a [...]

Discovering new, improved ways to meet unmet patient needs is why Mayo Clinic Research exists, and the teams in Orthopedic Biomechanics Laboratory and Sports Medicine Research are no exception. Director of both programs, Timothy Hewett, Ph.D., has conducted injury prevention research throughout his career. He published his first prospective study [...]

After decades of research, pharmacogenomics is “ready for prime time” so to speak. Mayo clinic is a leader in moving pharmacogenomics into clinical care — with the goal of helping providers identify medications that are compatible with their patients' genetic profiles. Drugs and Genes: Pharmacogenomics for the Modern Health Care [...]

Each year, more than one million women have biopsies that show non-cancerous changes in the breast, known as benign breast disease (BBD). Even though the changes may not require treatment, studies over the years at Mayo Clinic and elsewhere have found that not all cases of BBD are the same, [...]

This article originally appeared on the Center for Individualized Medicine blog on Oct. 15, 2018. Article by Sharon Rosen October is Breast Cancer Awareness Month, a time to reflect on new, individualized approaches to detecting and treating a cancer that affects 1 in 8 American women. Deborah Rhodes, M.D. and [...]

Although Mayo Clinic does not use genome editing as part of any treatment in the medical practice, genome editing has promise for treating and even curing previously intractable disorders, such as Duchenne muscular dystrophy. Genome editing, via methods like CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) can [...]

The Regenerative Medicine Therapeutic Suites has seen 1,000 patients since opening on Mayo Clinic’s Florida campus almost two years ago. The model, which integrated patient care with laboratory functions, is enabling the development and use of regenerative medicine products. The unique space serves both patients and clinicians, providing a place for multidisciplinary [...]

Mayo Clinic researchers have outlined diagnostic criteria for determining spinal cord strokes. One reviewer described their research, published in the Journal of the American Medical Association Neurology, as “a seminal paper” that will help diagnose spinal cord strokes, which oftentimes are misdiagnosed. “Spinal cord strokes can be confidently diagnosed by [...]

Michelle was the matriarch of a big Italian family. Her life revolved around taking care of others and her love language was food. When she was diagnosed with stage IV breast cancer, her life and family activities suddenly screeched to a halt. Her oncologist and health care team acted quickly [...]

On September 24, 2018, the National Institutes of Health  (NIH) awarded Mayo Clinic funding to serve as the new Metabolomics Research Core for the Undiagnosed Diseases Network. In this article, we explore the role of metabolomics in medicine at Mayo Clinic, both in research and in patient care. And we celebrate [...]

Often people with diabetes have brain changes that are hallmarks of both Alzheimer's disease and vascular dementia. Some researchers believe that each condition fuels the damage caused by the other. That link may occur as a result of the ways that type 2 diabetes affects the ability of the brain [...]

If you’re in California and see a dog outfitted in a snazzy vest with an electronic tablet, Spot, Fido or Lassie just might be participating in a Mayo Clinic epilepsy trial. Mayo Clinic and Medtronic are developing a next-generation epilepsy therapeutics platform that integrates brain implants with local and distributing computing [...]

The National Cancer Institute (NCI) has awarded Mayo Clinic an $11.5 million grant to fund  a Specialized Program of Research Excellence (SPORE) in hepatobiliary cancer through August 2023. Headed by principal investigators Mark A. McNiven, Ph.D., and Lewis R. Roberts, M.B., Ch.B., Ph.D., the goal of the Mayo Clinic Hepatobiliary [...]

Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. Read on for recent findings of Mayo Clinic Research: Mayo Clinic researchers receive [...]

Genes don't change, but how they are used by the body can.  That shift in use (which is called epigenetics) can mean the difference between illness and health. To better understand how that happens Mayo researchers are examining how genes are activated (used) and copied. With a recent publication in [...]

ICU use of PTZ/VAN combo therapy safe for kidneys Life threatening infections, or sepsis, are one of the most common reasons people end up in the intensive care unit or stay longer in the hospital than originally expected. To combat these infections, physicians can choose from several antibiotics, and often [...]

Article by Alex Generous Like stones formed in nature, kidney stones show signs of being partially dissolved and remade.  Implication: there may be a way to remove kidney stones without surgery or passing them in urine. An unlikely collaboration between a geologist at the University of Illinois Urbana-Champaign and researchers [...]