Medical breakthroughs start in the lab with a phase of research called discovery science. It helps to understand how the body functions and how disease begins at the most basic level. That in turn provides insight into how whatever has gone wrong can be fixed. To kick off the medical [...]

Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these [...]

There’s no getting around it: being a patient is hard work. And it gets even harder for patients living with multiple chronic conditions. This “work” is made of up all the responsibilities and tasks doctors ask patients to take on in order to access and use health care and in [...]

Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex [...]

Gastroenterologists agree that removing a colorectal polyp is an important step in preventing colon cancer, but one challenge has been excising polyps that are large, particularly those that are flat and more than an inch in diameter. A recently introduced minimally-invasive approach, called endoscopic mucosal resection, or EMR, facilitates the [...]

Every day more than 1,600 Americans die from cancer. Most of them have cancer that can’t be cured with traditional methods — surgery, radiation and chemotherapy. The father of Evanthia Galanis, M.D., was one of them. He died in the late 1990s from melanoma when his daughter was a junior faculty member at Mayo [...]

Regenerative Medicine Minnesota (RMM) recently announced the 2019 Regenerative Medicine Minnesota Research Awards. This year's research grants are aimed at developing better therapies for people with diabetes, cartilage injury, heart disease, cancer, chronic obstructive pulmonary disease, spinal cord injury, neurological disorders, and age-related macular degeneration. The grants are awarded to [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Minnesota Partnership awards 5 collaborative research grants Diabetes, stress-induced aging and Alzheimer's disease, [...]

Rosalie Sterner is already impressive, concurrently pursuing her M.D. and Ph.D. degrees through Mayo Clinic College of Medicine and Science. However, recently she made additional waves, as the lone medical student to receive the 2018 Outstanding Abstract Achievement Award from the American Society of Hematology. Sterner received this award and [...]

In a new study published in Mayo Clinic Proceedings, Mayo Clinic researchers present the first population-based evidence showing how often food allergies are diagnosed in people. The study also determined which foods are most likely to cause allergic reactions in different age groups. “There were no previous population-based estimates for [...]

Diversity and inclusion are integral to Mayo Clinic's mission to provide excellent, culturally relevant care in a welcoming environment to patients from a wide variety of backgrounds and creating an inclusive work environment where differences are valued, allowing individuals to achieve and contribute to their fullest potential. The women featured [...]

Practice advancements, scientific discoveries, product development and access to care were just a few of the topics featured at the 2018 Mayo Clinic Symposium on Regenerative Medicine and Surgery, held earlier this month in Scottsdale, Ariz. Over 200 providers, scientists, educators, students, entrepreneurs and patient advocates were in attendance to share knowledge [...]

By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who [...]

Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic's Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn't involve running shoes but nevertheless is paving the way to [...]

Though rare, cardiac sarcoidosis is a condition that can wreak havoc on the heart. It can be triggered by environmental or infectious agents and is characterized by an overactive immune response, involving clusters of white blood cells that aggregate in heart tissue. Those clusters can result in the need for [...]

Metformin is the recommended first line treatment for type 2 diabetes, and is often used to prevent progression of prediabetes to diabetes. Unfortunately, it will not work for over one third of patients who take it, a condition called “therapeutic failure.” Historically there has been little way of knowing whether [...]

Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food [...]

When you leave the hospital, following an injury, stroke, surgery or other event, you are loaded down with paper. You receive instructions on how to take care of your body. They tell you how to prepare your home and your family. Other pages include directions on what medication to take, [...]

Each month, we publish Mayo Clinic's Research News Roundup. This post includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. December's news releases highlight some of the wide variety of research being [...]

Were you good last year? If so (or even if not - we don't judge) you might enjoy these little gifts of new knowledge, ideas, technology, and more from Mayo Clinic Research. Read on to learn about some of our newest research programs. Explore some of our shiniest websites (so [...]

Each fall, millions of Americans roll up their sleeves for a flu shot, grateful for the quick pinch that may save them from the misery the flu can bring. In the not-too-distant future, there may be a poke with a much bigger payout. Scientists at Mayo Clinic and elsewhere are [...]

When a team of Mayo Clinic researchers discovered in 2011 the genetic repeat mutation known as c9orf72, the finding shed new light on amyotrophic lateral sclerosis (ALS). The mutation, which occurs as a short sequence of code repeated hundreds to thousands of times in the gene, is now known to [...]

Looking for a scientific conversation starter for New Year's Eve? Advancing the Science has you covered with this top-10 recap of our hottest medical research stories from 2018. With this list in your back pocket, you'll never run out of interesting cocktail banter. And we guarantee you'll wow your friends [...]

Your holiday gift list may include model planes or model rockets, but I hope it also includes the Mayo Model of Research. Haven’t you heard of it? It isn’t new but it is pretty amazing. It’s based around Mayo’s core value, the needs of the patient come first, as that [...]

Mayo Clinic researchers report that spinal cord inflammation associated with an antibody to myelin oligodendrocyte glycoprotein can mimic acute flaccid myelitis, a rare but serious disease linked to certain viruses that particularly affects children and can result in paralysis. The researchers show that detecting the MOG antibody has important treatment [...]