Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Jan 17, 2019

RIGHT 10K: Blazing a trail to health care's future

By Susan Buckles @susanbuckles
Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic's Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn't involve running shoes but nevertheless is paving the way to [...]
RIGHT 10K: Blazing a trail to health care's future
Jan 15, 2019

A hard look at a devastating heart disease

By Kate Ledger @k8ledger
Though rare, cardiac sarcoidosis is a condition that can wreak havoc on the heart. It can be triggered by environmental or infectious agents and is characterized by an overactive immune response, involving clusters of white blood cells that aggregate in heart tissue. Those clusters can result in the need for [...]
A hard look at a devastating heart disease
Jan 14, 2019

New algorithms help predict diabetes treatment failure

By Advancing the Science contributor @advancingthescience
Metformin is the recommended first line treatment for type 2 diabetes, and is often used to prevent progression of prediabetes to diabetes. Unfortunately, it will not work for over one third of patients who take it, a condition called “therapeutic failure.” Historically there has been little way of knowing whether [...]
New algorithms help predict diabetes treatment failure
Jan 10, 2019

Gene therapy: potential and pitfalls

By Susan Buckles @susanbuckles
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food [...]
Gene therapy: potential and pitfalls
Jan 9, 2019

Why doctors might need to go back to 6th grade

By Elizabeth Zimmermann @elizabethzimmermann
When you leave the hospital, following an injury, stroke, surgery or other event, you are loaded down with paper. You receive instructions on how to take care of your body. They tell you how to prepare your home and your family. Other pages include directions on what medication to take, [...]
Why doctors might need to go back to 6th grade
Jan 8, 2019

Research News Roundup-December 2018

By Elizabeth Zimmermann @elizabethzimmermann
Each month, we publish Mayo Clinic's Research News Roundup. This post includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. December's news releases highlight some of the wide variety of research being [...]
Research News Roundup-December 2018
Jan 7, 2019

One more gift for you in the new year

By Elizabeth Zimmermann @elizabethzimmermann
Were you good last year? If so (or even if not - we don't judge) you might enjoy these little gifts of new knowledge, ideas, technology, and more from Mayo Clinic Research. Read on to learn about some of our newest research programs. Explore some of our shiniest websites (so [...]
One more gift for you in the new year
Jan 3, 2019

A vaccine to prevent breast cancer? It's worth a shot

By Advancing the Science contributor @advancingthescience
Each fall, millions of Americans roll up their sleeves for a flu shot, grateful for the quick pinch that may save them from the misery the flu can bring. In the not-too-distant future, there may be a poke with a much bigger payout. Scientists at Mayo Clinic and elsewhere are [...]
A vaccine to prevent breast cancer? It's worth a shot
Jan 2, 2019

Toward clinical trials for one type of ALS

By Kate Ledger @k8ledger
When a team of Mayo Clinic researchers discovered in 2011 the genetic repeat mutation known as c9orf72, the finding shed new light on amyotrophic lateral sclerosis (ALS). The mutation, which occurs as a short sequence of code repeated hundreds to thousands of times in the gene, is now known to [...]
Toward clinical trials for one type of ALS
Dec 27, 2018

Be the life [science] of the party

By Caitlin Doran @caityrosey
Looking for a scientific conversation starter for New Year's Eve? Advancing the Science has you covered with this top-10 recap of our hottest medical research stories from 2018. With this list in your back pocket, you'll never run out of interesting cocktail banter. And we guarantee you'll wow your friends [...]
Be the life [science] of the party
Dec 24, 2018

Our gift to you this holiday season

By Sara Tiner @saratiner
Your holiday gift list may include model planes or model rockets, but I hope it also includes the Mayo Model of Research. Haven’t you heard of it? It isn’t new but it is pretty amazing. It’s based around Mayo’s core value, the needs of the patient come first, as that [...]
Our gift to you this holiday season
Dec 21, 2018

MOG antibody-associated spinal cord inflammation can mimic acute flaccid myelitis

By Advancing the Science contributor @advancingthescience
Mayo Clinic researchers report that spinal cord inflammation associated with an antibody to myelin oligodendrocyte glycoprotein can mimic acute flaccid myelitis, a rare but serious disease linked to certain viruses that particularly affects children and can result in paralysis. The researchers show that detecting the MOG antibody has important treatment [...]
MOG antibody-associated spinal cord inflammation can mimic acute flaccid myelitis
Dec 20, 2018

Discovery advances potential individualized treatment for mesothelioma

By Susan Buckles @susanbuckles
This article originally ran on the Center for Individualized Medicine blog on November 26, 2018 Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in [...]
Discovery advances potential individualized treatment for mesothelioma
Dec 19, 2018

A passion for serving underserved communities

By Advancing the Science contributor @advancingthescience
By LaPrincess Brewer, M.D  I don't have the classic story, where as a child, I dreamed of being a physician and went around wearing a toy stethoscope and carrying a doctor's bag. I discovered my love of patient care and medicine after my freshman year at Howard University in Washington, [...]
A passion for serving underserved communities
Dec 18, 2018

Study shows better outcomes for women treated for uterine fibroids with UAE

By Advancing the Science contributor @advancingthescience
A multicenter study led by Mayo Clinic researchers shows that women who undergo uterine artery embolization (UAE) for symptomatic uterine fibroids are less likely to need a second procedure compared to women who were treated by magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS). The results are published online in the [...]
Study shows better outcomes for women treated for uterine fibroids with UAE
Dec 17, 2018

Reflections of a student: Spinal cord stimulation research, results of intraoperative electrode techniques

By Advancing the Science contributor @advancingthescience
As a predoctoral student in the Mayo Clinic Graduate School of Biomedical Sciences, I’ve had the opportunity to work on a project investigating the use of epidural electrical stimulation and intense physical therapy to help people with chronic paralysis regain movement following spinal cord injury. In a recent article in [...]
Reflections of a student: Spinal cord stimulation research, results of intraoperative electrode techniques
Dec 13, 2018

The sky's the limit

By Advancing the Science contributor @advancingthescience
In 2011, Jared Ausnehmer left his local hospital carrying the weight of an oxygen tank and the worry of what might come next. At age 21, he’d already defied the odds for those born with hypoplastic left heart syndrome, a birth defect in which the left side of the heart [...]
The sky's the limit
Dec 12, 2018

Father's battle with kidney disease fuels researcher's determination to find cure

By Advancing the Science contributor @advancingthescience
Fouad Chebib, M.D., grew up in a small town in Lebanon. After finishing medical school in Beirut, Dr. Chebib chased his dream across the world to Mayo Clinic. That dream was finding a cure for polycystic kidney disease, or PKD, a genetic defect or mutation that results in the formation of [...]
Father's battle with kidney disease fuels researcher's determination to find cure
Dec 11, 2018

New Mayo research focused on how women's hormones affect aging

By Advancing the Science contributor @advancingthescience
By Heather Carlson Kehren Mayo Clinic researchers are taking a closer look at differences in how women age and the role hormones may play in the process. To do that, they will focus on premenopausal women who have had both of their ovaries removed. Investigators will be looking to see [...]
New Mayo research focused on how women's hormones affect aging
Dec 10, 2018

Novel data-driven approach for precision medicine

By Colette Gallagher @colettegallagher
Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report [...]
Novel data-driven approach for precision medicine
Dec 5, 2018

Two minutes to win it

By Lynda de Widt @ldewidt
Nine teams of Mayo Clinic employees pitched their ideas for health care innovations at the second annual Alligator Tank competition at the Mayo Clinic Florida campus on November 14, 2018.  Each team was given 120 seconds to explain their solution to a problem in the medical field before a live [...]
Two minutes to win it
Dec 4, 2018

Research News Roundup -- November 2018

By Elizabeth Zimmermann @elizabethzimmermann
The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. How viruses hijack part of your immune system and use it against you An enzyme intended to [...]
Research News Roundup -- November 2018
Nov 29, 2018

The right diet for you... or for your gut microbes?

By Sara Tiner @saratiner
This article originally appeared on the Center for Individualized Medicine blog on Oct. 10, 2018. The right diet, obesity and gut health are topics patients, clinicians and scientists wrestle with every day. We want to eat a good diet and lose weight or avoid weight gain, so our health span [...]
The right diet for you... or for your gut microbes?
Nov 28, 2018

Stem cells and chronic kidney disease

By Jennifer Schutz @jenniferschutz
Millions of Americans have chronic kidney disease. Hundreds of thousands will progress to end stage kidney disease requiring either dialysis or kidney transplant. But research is underway to keep people from reaching that point. “Our goal is to take a look at how we can repair the diabetic kidney in terms [...]
Stem cells and chronic kidney disease
Nov 27, 2018

A mother's milestone

By Advancing the Science contributor @advancingthescience
This last summer, Stacy Erholtz celebrated another blessed event with her family. The oldest of her three children was married. "I never, never in my wildest dreams, thought I would be able to participate in that beautiful, joyful event," Stacy says as she wipes away tears that come easily whenever [...]
A mother's milestone
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