By Jay Furst Low vitamin B12 levels can worsen some symptoms of Parkinson's disease, especially postural instability and cognitive impairment, which can lead to falls and injuries, researchers say. Lower vitamin B12 levels also are associated with higher Hoehn-Yahr stage, the tool for assessing disease severity, and neuropathy in Parkinson's [...]

Regenerative medicine is redefining clinical care—going beyond disease symptom management to addressing the underlying cause of disease to restore health. Regenerative care is expected to represent 10% of all health care in the next decade. Yet, education in regenerative medicine lags behind scientific and clinical advances. This threatens to leave physicians-in-training ill-equipped [...]

By Jay Furst Computed tomography (CT), which uses specialized X-rays to create images of areas inside the body, has revolutionized medicine in the nearly 50 years since it became commonly available. From kidney stones to cancer, CT has become an indispensable diagnostic tool. In 1980, an estimated 3 million CT [...]

T-cells are having a moment. Well maybe not like Game of Thrones is having a moment, but as stars of the cancer treatment, immunotherapy, T-cells are definitely cool. But what is a T-cell? And how can you get one? Good news! Your body makes T-cells for you, a lot of [...]

Bithika Thompson, M.D., an endocrinologist at Mayo Clinic in Phoenix, and M. Adela Grando, PhD., a biomedical informaticist at Arizona State University, recently teamed up on a health care research project that could transform the way individuals manage their diabetes. Type 1 diabetes is a chronic disease that affects more [...]

Mayo Clinic Ventures commercializes technologies to benefit patients while generating revenue to support clinical practice, research and education. Thanks in part to licensing and partnership efforts, 2018 was a banner year for Mayo Clinic Ventures' financial performance. By Kate Stober Mayo Clinic has a long and storied history of firsts [...]

According to the International Osteoporosis Foundation, more than 200 million people worldwide suffer from osteoporosis, or insufficient regeneration of bone tissue and fragile bones. At least 40% of postmenopausal women and 15-30% of older men will sustain one or more fractures due to fragility. Osteopenia, a lesser form of bone [...]

Left: Peter Grahn, Ph.D., and Megan Gill, D.P.T.. Right: Megan Gill, D.P.T., (seated) assists Jered Chinnock as part of a clinical trial to determine if spinal cord circuitry can be modulated with electrical stimulation and rehabilitation to restore function lost to paralysis. Mayo Clinic has challenged its researchers to transform [...]

Drs. Tatum (left) and Quinones-Hinojosa using brain mapping during a procedure. Surgeons in the operating room must achieve a delicate balance when removing a brain tumor: eradicate as much of the cancer as possible, and avoid injury to parts of the brain responsible for motor control, speech, and more. For [...]

2019 Regenerative Medicine and Surgery Selective Bringing regenerative medicine to more patients requires highly skilled medical providers. During a recent weeklong educational course, 42 medical and graduate students were immersed in regenerative medicine at Mayo Clinic. The Regenerative Medicine and Surgery Selective introduces students to regenerative medicine and surgery by [...]

Mayo Clinic’s CT Clinical Innovation Center recently released the first-ever quantitative Stone Analysis Software (qSAS) for characterizing renal stones from CT images. The product is available at no charge for research use through a software sharing agreement. Cynthia McCollough, Ph.D., Division of Medical Physics, Department of Radiology at Mayo Clinic [...]

Every year the American Society of Clinical Oncology (ASCO) hosts a gathering of cancer researchers and clinicians from around the world to teach and learn from each other, sharing their research and innovations in patient care. ASCO's mission is "conquering cancer through research education, and promotion of the highest quality [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research- and research education-related news releases from the past month. It also connects readers to additional resources of relevance. Read on for more information from Mayo Clinic Research. Mayo experts to present findings at Digestive Disease Week 2019 [...]

Amyloidosis is a rare disease that occurs when a substance called amyloid builds up in your organs. Amyloid is an abnormal protein that is produced in your bone marrow and can be deposited in any tissue or organ. Hereditary amyloidosis (familial amyloidosis) is an inherited disorder that often affects the [...]

AcademyHealth's Annual Research Meeting, June 2-4, 2019, in Washington, D.C., showcases "Today's research driving tomorrow's outcomes." It is an ideal venue to share research findings from across the continuum of health care delivery. The Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery [...]

Regenerative science has advanced next-generation technologies from the research bench to potential clinical care options. But in the rigorous development of patient therapies, it is critical to validate the safety and efficacy of regenerative solutions. Shane Shapiro, M.D. Shane Shapiro, M.D., medical director of the Regenerative Medicine Therapeutics Suites on [...]

The World Health Organization recognizes Friday, May, 31, as World No Tobacco Day – the perfect time to celebrate Mayo Clinic’s participation in the National Cancer Institute (NCI) Cancer Center Cessation Initiative.  Launched in 2017 as part of the NCI Cancer Moonshot program, the long-term goal of this initiative is to [...]

Article by Barbara Toman A young person's sudden death from cardiac arrest is doubly devastating. Just when family members are mourning the unexpected loss, they might also be wondering if tArhe cause was inherited heart disease — and if they too are at risk. Often there's no easy answer. Unlike [...]

A new study suggests that remotely delivering rehabilitation services to patients with late-stage cancer improves their physical function, pain and quality of life while allowing them to spend less time in hospitals and nursing homes. The results of a randomized clinical trial with 516 participants, led by Andrea Cheville, M.D., [...]

In many states, women can expect pregnancy to restrict their advance directives. Search online for what to do when getting ready for baby and you’ll find endless checklists of essentials every parent needs, from onesies and diapers to high tech strollers and baby monitors. The best lists also mention an [...]

Mayo shares neurological research and advancements at AAN meeting Among more than 15,000 attendees at the 2019 American Academy of Neurology (AAN) Annual Meeting in Philadelphia, May 4-10, Mayo Clinic had a strong presence. Mayo scientists and clinicians led 38 courses and gave 84 lectures at the world's largest gathering [...]

By Jay Furst Blood clots moving to the brain are a frequent -- and dangerous -- complication for patients with endocarditis. Endocarditis is an infection of the heart's inner lining that can damage heart valves and contribute to the formation of blood clots. As many as 80 percent of endocarditis [...]

SPARK students pose with their Mayo research mentors Lights…camera…action! Mayo Clinic and its successful research mentoring program, known as SPARK, took center stage at the St. Johns County School District Academy Awards on April 2. The awards recognize members of Florida’s business community for opportunities and resources they provide to [...]

In the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, every project is inspired by real-world challenges experienced by patients at Mayo Clinic and elsewhere. Together with Mayo Clinic's health care providers, center experts research ways to improve outcomes for patients across [...]

As many as 25 million Americans – about 1 in 13 people - suffer from a rare, undiagnosed condition.* April 29 was designated Undiagnosed Disease Day to raise awareness that collectively, rare diseases are relatively common. People with a rare disease often spend years visiting different medical providers and clinics [...]