Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Feb 20, 2020

Restoring function with larynx transplantation

By Jennifer Schutz @jenniferschutz
Mayo Clinic has launched a first of its kind regenerative transplant program aimed at restoring function for people who need their larynx, or voice box, removed. In the United States about 60,000 people are living without a larynx, due to disease or trauma. The larynx is a segment of the respiratory [...]
Restoring function with larynx transplantation
Feb 19, 2020

Researchers identify 7 best practices for physicians working with dementia caregivers

By Adam Harringa @harringaadam
People with Alzheimer’s disease and other forms of dementia often rely on family caregivers to plan or assist with their medical care. But caregivers are not usually fully integrated in their family members’ clinical appointments or care plan. To identify gaps in care and communication, Mayo Clinic researchers have identified seven best practices for health care providers [...]
Researchers identify 7 best practices for physicians working with dementia caregivers
Feb 18, 2020

Mayo researchers studying 'promising' new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy @susanmurphy
A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of [...]
Mayo researchers studying 'promising' new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time
Feb 17, 2020

AI system helps individualize treatment people diagnosed with depression

By Advancing the Science contributor @advancingthescience
When searching for an exact diagnosis through a myriad of complex and serious factors spread across millions of data points, it helps to have a powerful magnifying glass — and another expert point of view. Enter Arjun Athreya, Ph.D., an engineer by trade who has a knack for bringing together data [...]
AI system helps individualize treatment people diagnosed with depression
Feb 14, 2020

Filling hearts instead of test tubes

By Advancing the Science contributor @advancingthescience
Editor's note: This story is not about Mayo Clinic research, but rather about a part of a researcher's life that builds hope in little hearts, and gives him joy. It's 10 a.m. on a Thursday, and Merrick Ducharme is up to his elbows (OK, his wrists) in slime. The gooey, gluey [...]
Filling hearts instead of test tubes
Feb 13, 2020

Embracing clinical research with 'both feet and hands'

By Caitlin Doran @caityrosey
Adrian Vella, M.D., says medical careers run like a hereditary condition in his family. “My father is a physician, my brother is a surgeon, and there are lots of medical people on my mother’s side as well.” So it was almost inevitable that, from an early age, he thought about [...]
Embracing clinical research with 'both feet and hands'
Feb 11, 2020

Clinical Decision Support: Making It Easy to Do the Right Thing

By Advancing the Science contributor @advancingthescience
According to the Office of the National Coordinator for Health Information Technology, clinical decision support provides clinicians, staff, patients or other individuals with knowledge and person-specific information, intelligently filtered or presented at appropriate times, to enhance health and health care. At Mayo Clinic there are a range of activities surrounding [...]
Clinical Decision Support: Making It Easy to Do the Right Thing
Feb 10, 2020

Regenerative product could provide new option for women with mesh exposure following pelvic reconstructive surgery

By Jennifer Schutz @jenniferschutz
Research is advancing a regenerative solution for a quality of life-limiting complication of mesh-based surgical repairs for stress urinary incontinence and pelvic organ prolapse in women. While mesh-based surgical treatments are durable and provide symptom relief for a great number of patients, there is a risk of mesh complications following [...]
Regenerative product could provide new option for women with mesh exposure following pelvic reconstructive surgery
Feb 7, 2020

Toxic Protein, Linked to Alzheimer's and Other Neurodegenerative Diseases, Exposed in New Detail

By Advancing the Science contributor @advancingthescience
By Zuckerman Institute Communications Staff The protein tau has long been implicated in Alzheimer’s and a host of other debilitating brain diseases. But scientists have struggled to understand exactly how tau converts from its normal, functional form into a misfolded, harmful one. Now, researchers at Columbia University’s Zuckerman Institute and Mayo [...]
Toxic Protein, Linked to Alzheimer's and Other Neurodegenerative Diseases, Exposed in New Detail
Feb 6, 2020

Improving the quality of life for the aging population in Rochester and beyond

By Advancing the Science contributor @advancingthescience
By Adolfo Espitia Jr., public affairs intern Diagnosed with pulmonary hypertension some years ago, Elizabeth, now 65, was left with a debilitating condition that prevented her from even light activities. She had to rely on her husband to take care of their home. Finally, the medications she had taken for 10 years stopped working, forcing [...]
Improving the quality of life for the aging population in Rochester and beyond
Feb 5, 2020

"I Just Didn't Understand": On a Mission to Cure ALS

By Advancing the Science contributor @advancingthescience
By Barbara J. Toman For Veronique Belzil, Ph.D., the fight against amyotrophic lateral sclerosis (ALS) is personal. In 2000, while working as a psychologist in Canada, she watched her husband's uncle succumb to the disease. "The progression was so fast and his condition was so sad," she says. "I just [...]
Feb 4, 2020

Research News Roundup--January 2020

By Elizabeth Zimmermann @elizabethzimmermann
If you're interested in genetics, diabetes, transplant or robotics, January was a good month. The Mayo Clinic Research News Roundup includes brief summaries and links to these and a tidy sum of other recent research-related news releases from Mayo Clinic. You also might find some other handy resources. Read on for more information [...]
Research News Roundup--January 2020
Feb 3, 2020

Merging minds to accelerate research discovery

By Advancing the Science contributor @advancingthescience
Mayo Clinic and Arizona State University formed the Mayo Clinic-Arizona State University Alliance for Health Care in 2010 to merge minds and accelerate research discoveries, improve patient care through innovation and transform medical education to enhance health outcomes. Highlights of two of the joint research efforts follow. Identifying a blood-based [...]
Merging minds to accelerate research discovery
Jan 31, 2020

How a love for learning inspired an investment in physicians of the future

By Advancing the Science contributor @advancingthescience
Jay Alix grew up surrounded by an unlikely team of experts. That, and a supportive community, gave him a push that turned him into a world-class business leader. Now a member of the Mayo Clinic Board of Trustees, he’s sharing his legendary business acumen to help Mayo Clinic educate the [...]
How a love for learning inspired an investment in physicians of the future
Jan 30, 2020

A breakthrough in distinguishing benign adrenal tumors from cancerous ones

By Advancing the Science contributor @advancingthescience
By Christoph Bahn Approximately 80 million CT scans are performed in the United States every year. Adrenal tumors are found incidentally in about 5% of these scans. Most of these tumors will turn out to be benign, but a small fraction will be adrenal cortical carcinoma, a type of cancer with high mortality [...]
A breakthrough in distinguishing benign adrenal tumors from cancerous ones
Jan 29, 2020

A case for public health initiatives

By Elizabeth Zimmermann @elizabethzimmermann
COPD is a chronic lung disease that makes it difficult to breath. According to the American Lung Association, COPD is the third leading cause of death in the U.S., with more than 15 million people currently living with the disease. It also increases the likelihood that people will develop heart disease, lung cancer [...]
A case for public health initiatives
Jan 28, 2020

A look into the RAD Labs: Vascular and interventional radiology translational research

By Advancing the Science contributor @advancingthescience
By Maria Ly, undergraduate public affairs intern Sanjay Misra, M.D., an interventional radiologist, in 2010 launched a lab focused on improving existing therapies and creating new treatments to help patients with renal disease. Funded by grants from the National Institutes of Health, American Heart Association, and Mayo Clinic, the [...]
A look into the RAD Labs: Vascular and interventional radiology translational research
Jan 27, 2020

Neuro regeneration for chemo brain: Mi-Hyeon Jang, Ph.D.

By Jennifer Schutz @jenniferschutz
Cognitive dysfunction, sometimes called "chemo brain," stemming from chemotherapy is a major adverse condition affecting approximately 14 million cancer patients and survivors in the United States. Although chemo brain has been widely reported by patients and clinicians, the cause of concentration and memory problems in cancer patients is not well [...]
Neuro regeneration for chemo brain: Mi-Hyeon Jang, Ph.D.
Jan 24, 2020

The Compass offers direction on biomedical issues

By Advancing the Science contributor @advancingthescience
By Jay Furst A compass, whether the old-fashioned kind in a brass case or the hands-free version on your dashboard, provides direction and helps you to find your way. The word's Latin origin, though, is about more than navigation. It's the root of the word "compassion," which implies feeling, connectedness and [...]
The Compass offers direction on biomedical issues
Jan 23, 2020

Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders

By Susan Buckles @susanbuckles
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also could lead to new strategies for treating [...]
Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders
Jan 22, 2020

What's Next for The Research of the Future

By Sara Tiner @saratiner
Breakthroughs in medical science rarely burst on the scene. Behind every advance is years of work by dogged researchers who nurtured the seed of idea until it flowered, bore fruit and materialized into a better treatment, device or therapy for patients. Here is where those seeds start: More than a [...]
What's Next for The Research of the Future
Jan 20, 2020

Platelet rich plasma found to be effective in regrowing hair

By Jennifer Schutz @jenniferschutz
Platelets spun from a person’s own blood may be a new option for treating baldness in women, according to research at Mayo Clinic’s Florida campus. A pilot study found platelet rich plasma (PRP), a regenerative therapy associated with natural growth factors and tissue healing, regrows hair as well as other treatments on [...]
Platelet rich plasma found to be effective in regrowing hair
Jan 17, 2020

Did you know? Mayo Clinic publishes two peer-reviewed journals

By Elizabeth Zimmermann @elizabethzimmermann
Continuously published since 1926, Mayo Clinic Proceedings is a peer-reviewed journal, ranked among the top 10% of the 160 clinical journals in the Medicine, General and Internal category. The journal has a distribution of approximately 127,000. Articles published in peer-reviewed journals have been reviewed by experts in the relevant field to [...]
Did you know? Mayo Clinic publishes two peer-reviewed journals
Jan 16, 2020

Patient-centered research originates across health care

By Advancing the Science contributor @advancingthescience
Patient-centered research. It's this kind of research that leads to practice transformation - improving outcomes, costs and overall experience with health and health care. And patients are the reason Kirsten Holbrook, a supervisor in the Respiratory Care Department, Mayo Clinic Health System Eau Claire, Wisconsin, decided to conduct a research project. Holbrook [...]
Patient-centered research originates across health care
Jan 15, 2020

My Mouth Is Not Watering: The Perplexing World of Salivary Gland Pathology

By Advancing the Science contributor @advancingthescience
So in mid-January, the holiday season is still fresh in your mind. Quite likely it was a time when you made full use of your senses of smell and taste. Mmmm. Just thinking about cookies baking in the kitchen is enough to get your mouth watering. So what happens if your [...]
My Mouth Is Not Watering: The Perplexing World of Salivary Gland Pathology
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