The major challenge in treating obesity is not just losing weight, but preventing weight from coming back. With a research grant form Regenerative Medicine Minnesota, Ping (Vicky) Chen, Ph.D., Mayo Clinic research associate,  is studying a new treatment strategy using gene transfer therapy to safely target brain mechanisms that control [...]

This post originally was published on the Center for Individualized Medicine blog on June 25, 2018 Article by Heather Carlson Women going through menopause know all too well the discomfort associated with night sweats. Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen [...]

By Julie Sokoloski Research developments in aging, including research done here at Mayo Clinic, will be highlighted throughout late August in a PBS special, “Incredible Aging: Adding Life to Your Years." Hosted by 14-time Emmy Award-winner, executive producer, and anchor Meredith Vieira, the program provides a blueprint for healthy aging. [...]

This article originally appeared on the Center for Individualized Medicine blog on May 28, 2018. Mayo Clinic laboratory workers have a new tool to perform high tech genetic sleuthing for the source of stubborn, sometimes life-threatening bacteria. Bacterial whole genome sequencing can trace individual isolates of bacteria such as Staphylococcus [...]

Expanding on previous findings, a group of Mayo researchers continue using discovery research in cells to find options for treating cancers. In their most recent paper, published in Molecular Cell, the team's research suggest that a drug used for breast cancer may be helpful in some types of prostate cancers. [...]

Starting at age 8, Jan van Deursen, Ph.D., helped his carpenter father on the weekends when he built custom staircases, windows and doors for people in their village in the Netherlands. “My father had a fast pace, and I had to keep up with him,” says Dr. van Deursen. “I didn’t [...]

A life-saving procedure improves fetal lung health and reduces post-natal complications Specialists at Mayo Clinic are pioneering a life-saving procedure as part of a clinical trial for babies with congenital diaphragmatic hernia (CDH). When a baby’s lungs are not adequately developed at birth, severe complications and even death can result. Waiting [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In [...]

Mrinal Patnaik, M.B.B.S., is a physician in the Department of Hematology at Mayo Clinic with a keen interest in the clinical management of blood cancers. In recent years, however, Dr. Patnaik realized he wanted to develop a deeper understanding of the disease biology of these cancers and the ways that [...]

This article originally appeared on the Center for Individualized Medicine blog on June 4, 2018. Article by Barbara Toman Just as money in the bank boosts your financial well-being, biobanks have the power to impact your health. Think of biobank samples as assets that researchers can draw upon to improve [...]

At Mayo Clinic, research is integral to everything we do. We would be unable to offer the highest possible levels of care and continually improve the practice of medicine without research, and the education programs and processes that underpin our care. Our research web is actually just a section of Mayo Clinic's internet presence, [...]

Abstracts are now being accepted for the Mayo Clinic Symposium on Regenerative Medicine and Surgery. The symposium will be held Nov. 29-Dec. 1, 2018 at the Westin Kierland Resort & Spa in Scottsdale, Arizona. Interested physicians, researchers, medical students, post-doctoral and pre-doctoral students, as well as allied health staff, are invited [...]

Over the last few years, immunotherapy using immune checkpoint inhibitors targeting programmed cell death receptor 1 (PD-1) or programmed cell death receptor ligand 1 (PD-L1) has revolutionized the therapeutic approach to advanced-stage non-small cell lung cancer and numerous other malignancies. Monotherapy, using the anti-PD-1 antibody pembrolizumab, is now Food and [...]

About 30 Mayo Clinic scientists are presenting at this week’s Alzheimer’s Association International Conference in Chicago, and another roughly two dozen researchers are contributing authors. They’re among more than 5,600 scientists from 65 countries. The schedule and abstracts are available on the Alzheimer’s Association conference website. All the research has one [...]

New imaging technologies are advancing diagnosis and individualizing care. Imaging tests – such as a CT scan or MRI – are essential tools that health care providers use to answer complex and challenging questions. Gabriel Krestin, M.D., Ph.D., a radiologist and researcher, is at the forefront of new efforts to [...]

When was the last time a movie really made you think, changed how you viewed the world or helped you understand an important topic? Bioethics at the Cinema, organized by the Mayo Clinic Biomedical Ethics Program and the Rochester Public Library, wants to do just that. The goal is to use [...]

Joseph Lillegard, M.D., Ph.D., is a Regenerative Medicine Minnesota research grant recipient. He is researching gene therapy to fight inborn errors of metabolism of the liver, primarily Hereditary Tyrosinemia Type 1 (HT1), a metabolic disorder caused by an enzyme deficiency. HT1 is a genetic disorder that can lead to liver and kidney [...]

This post originally appeared on the Center for Individualized Medicine blog on May 15, 2018. Article by Barbara Toman Melanoma, the skin cancer often associated with sun exposure, is on the rise and has no reliable cure. Mayo Clinic is at the forefront of efforts aimed at increasing early detection and treatment [...]

Breast cancer survivors are not getting the recommended level of post-surgery screening, according to a study published in the May 2018 issue of the Journal of the National Comprehensive Cancer Network (JNCCN).  Contrary to screening recommendations, mammography rates decline over time as women get further out from their breast cancer [...]

Among cancers, liver tumors have been particularly hard for doctors to treat. The cancer cells tend to be hardy from the beginning and even undergo changes that make them more resistant to chemotherapies. What’s clear is that an effective treatment needs to reach the cancer cells, and not affect or [...]

For many patients, clinical trials offer a chance to benefit from promising new treatments that are not available in the doctor’s office. Yet not all people have the same access to these opportunities. Groups such as racial minorities, older individuals, and those with low income are less likely than others [...]

Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month's Roundup includes a number of findings related pancreatic cancer and [...]

Mark Truty, M.D., has dedicated his career to giving patients with pancreatic cancer more quality time with their loved ones. Much more time. The mission is personal for him. His own father, Kazimierz Truty, a Polish immigrant and mechanic at a meatpacking plant near Chicago, died 20 years ago from pancreatic [...]

Researchers at Mayo Clinic have developed a new, minimally invasive method to detect and help prevent esophageal cancer in patients at risk for Barrett's esophagus and esophageal cancer. Their study documenting the discovery and validation of novel methylated markers along with results of a pilot study have been published and [...]

Death. Dying. End of life care. Comfort care. Hospice. In the face of losing someone that we love whether they are young or old; hearing these words uttered and the paralyzing finality and irrevocability of it all compounds the already difficult circumstances. These words conjure up an even more poignant [...]