Although Mayo Clinic does not use genome editing as part of any treatment in the medical practice, genome editing has promise for treating and even curing previously intractable disorders, such as Duchenne muscular dystrophy. Genome editing, via methods like CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) can [...]

The Regenerative Medicine Therapeutic Suites has seen 1,000 patients since opening on Mayo Clinic’s Florida campus almost two years ago. The model, which integrated patient care with laboratory functions, is enabling the development and use of regenerative medicine products. The unique space serves both patients and clinicians, providing a place for multidisciplinary [...]

Mayo Clinic researchers have outlined diagnostic criteria for determining spinal cord strokes. One reviewer described their research, published in the Journal of the American Medical Association Neurology, as “a seminal paper” that will help diagnose spinal cord strokes, which oftentimes are misdiagnosed. “Spinal cord strokes can be confidently diagnosed by [...]

Michelle was the matriarch of a big Italian family. Her life revolved around taking care of others and her love language was food. When she was diagnosed with stage IV breast cancer, her life and family activities suddenly screeched to a halt. Her oncologist and health care team acted quickly [...]

On September 24, 2018, the National Institutes of Health  (NIH) awarded Mayo Clinic funding to serve as the new Metabolomics Research Core for the Undiagnosed Diseases Network. In this article, we explore the role of metabolomics in medicine at Mayo Clinic, both in research and in patient care. And we celebrate [...]

Often people with diabetes have brain changes that are hallmarks of both Alzheimer's disease and vascular dementia. Some researchers believe that each condition fuels the damage caused by the other. That link may occur as a result of the ways that type 2 diabetes affects the ability of the brain [...]

If you’re in California and see a dog outfitted in a snazzy vest with an electronic tablet, Spot, Fido or Lassie just might be participating in a Mayo Clinic epilepsy trial. Mayo Clinic and Medtronic are developing a next-generation epilepsy therapeutics platform that integrates brain implants with local and distributing computing [...]

The National Cancer Institute (NCI) has awarded Mayo Clinic an $11.5 million grant to fund  a Specialized Program of Research Excellence (SPORE) in hepatobiliary cancer through August 2023. Headed by principal investigators Mark A. McNiven, Ph.D., and Lewis R. Roberts, M.B., Ch.B., Ph.D., the goal of the Mayo Clinic Hepatobiliary [...]

Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. Read on for recent findings of Mayo Clinic Research: Mayo Clinic researchers receive [...]

Genes don't change, but how they are used by the body can.  That shift in use (which is called epigenetics) can mean the difference between illness and health. To better understand how that happens Mayo researchers are examining how genes are activated (used) and copied. With a recent publication in [...]

ICU use of PTZ/VAN combo therapy safe for kidneys Life threatening infections, or sepsis, are one of the most common reasons people end up in the intensive care unit or stay longer in the hospital than originally expected. To combat these infections, physicians can choose from several antibiotics, and often [...]

Article by Alex Generous Like stones formed in nature, kidney stones show signs of being partially dissolved and remade.  Implication: there may be a way to remove kidney stones without surgery or passing them in urine. An unlikely collaboration between a geologist at the University of Illinois Urbana-Champaign and researchers [...]

This article originally appeared on the Mayo Clinic Center for Individualized Medicine blog on August 27, 2018 Creating tools to detect cancer at an early stage and advancing research into the genetic links to Parkinson’s disease are focuses of the 2018 Gerstner Family Career Development Awards. This year’s winners are [...]

Recent practice advancements, scientific discoveries, product development and manufacturing are the topics featured at the 2018 Mayo Clinic Symposium on Regenerative Medicine and Surgery. Regenerative medicine leaders from around the globe will come together Nov. 29 – Dec. 1 at the Westin Kierland Resort in Scottsdale, AZ. This year’s symposium will emphasize clinical [...]

This article originally appeared on the Center for Individualized Medicine blog on Sept. 17, 2018. Article by Sharon Rosen Mining information deeper than genomics, understanding factors linked to disease, analyzing big data, and addressing the challenges of bringing all this information together to advance patient care – these were some [...]

Liver disease? Me? I don’t drink. I don’t smoke. Okay, so I don’t exercise that much, and where did all these candy bar wrappers come from? Anyway, I thought liver disease was just for alcoholics? These are question many Americans ask when diagnosed with nonalcoholic fatty liver disease. But as [...]

Katrina Croghan is clinical research coordinator for Mayo Clinic Cancer Center, assigned to the division of Hematology in Rochester, Minnesota. She began her career in ecology and animal science, but while en route to a related Ph.D., ended up as a supplemental research coordinator because of her knowledge of writing protocols and conducting [...]

Shoots to facilitate missions to Mars and improve health on Earth A full year before Alejandro Rabinstein, M.D., was born in Cordoba, Argentina, Apollo 11 made the first successful landing on the moon and U.S. astronaut Neil Armstrong became the first person to set foot on another planet. That was the summer of [...]

Graduates of Mayo Clinic Graduate School of Biomedical Sciences’ Ph.D. program in Clinical and Translational Science learn the skills to engage in research across the translational research spectrum, from laboratory-based, to patient-based, to population-based.  The goal is to give the next generation of clinical researchers the skills they need to [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Mayo Clinic researchers identify a potential new approach to treat HER2 positive breast cancer Researchers at Mayo [...]

When Burt Ramaker left the hospital following a successful hip replacement, he didn’t plan to go back any time soon. He and his wife Ardis imagined they would spend time at a skilled nursing facility to get him back on his feet, and then they’d be back at their waterfront [...]

On August 9, 2018, a community garden in Rochester, Minnesota hosted an unusual gathering: a cook-out and a community conversation on mental illness. At this meeting, more than a dozen members of the community assembled—grill tongs in hand—along with public health professionals and health researchers from Mayo Clinic, to talk [...]

Alexander Revzin, Ph.D., is a professor of biomedical engineering at Mayo Clinic and recipient of a 2018 Regenerative Medicine Minnesota Research Award. He is developing microcapsules that could be used as cell carriers during differentiation of stem cells into pancreatic islets. These same capsules may also be useful as vehicles [...]

This article originally appeared in the Center for Individualized Medicine blog on July 23, 2018 For as long as he can remember, Saad Kenderian, M.B., Ch.B., wanted to be a physician. Nothing could blunt his resolve –not even when improvised explosive devices, bombs and trappings of war put the medical [...]

Vitamin D, sometimes referred to as the ‘sunshine vitamin,’ comes up frequently in the clinical setting. Over the last few decades, we have learned that vitamin D may actually have a much broader role in human health than once thought. A deficiency in vitamin D is very common, mainly due [...]