Forefront is the complimentary magazine of the Mayo Clinic Cancer Center. Published in email and online newsletter editions quarterly, Forefront highlights Mayo Clinic’s cutting-edge cancer research and the latest Cancer Center news. The June 2019 issue features: Director’s message: Prioritizing cancer researchFederal cancer research funding is vital to meet growing [...]

Mayo Clinic Alix School of Medicine launched a Wilderness and Austere Medicine selective to teach students how to provide care for individuals injured in resource-limited and diverse environmental conditions. A unique component of the medical school’s individualized learning is the 25 weeks of “selective” time protected within the first two [...]

Peter Grahn, Ph.D., a senior engineer in the Department of Neurologic Surgery and alumnus of Mayo Clinic Graduate School of Biomedical Sciences In 2010 Peter Grahn, Ph.D., attended an annual research symposium in Minneapolis hosted by the Morton Cure Paralysis Fund. Among the leading spinal cord injury researchers speaking was [...]

By Maria Ly Early diagnosis will ultimately be essential in the management and treatment of Alzheimer’s disease. Examination of Alzheimer’s biomarkers can improve the prediction of short-term memory decline in middle-age and elderly individuals, according to new researchfrom Mayo Clinic. A new diagnostic framework developed in collaboration with the National [...]

Kenton Kaufman, Ph.D. Kenton Kaufman, Ph.D., departments of Orthopedic Surgery and Physiology and Biomedical Engineering at Mayo Clinic in Rochester, is a veteran investigator of limb amputation and prostheses with more than 25 years of experience. He’s on the Medical Advisory Board of Prosthetics 2020, an initiative of the American [...]

Mayo Clinic will host the 6th Annual Metastatic Breast Cancer Conference at the Omni Scottsdale Resort and Spa at Montelucia in Scottsdale, Arizona, Sept. 19–20. This program is a joint effort among Mayo Clinic, Baylor College of Medicine, and Theresa's Research Foundation. The Metastatic Breast Cancer Conference was established as an annual [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Study finds value in physician-patient outcome assessment process Sometimes a physician thinks the outcome of a patient's [...]

Lately the news has contained many stories of illness or death that could have been prevented by vaccination. Although in 2019 the stories have mostly been about measles, in 2016 it was pertussis, or whooping cough, as it was in 2012, and 2004-2005. The Centers for Disease Control estimates 24.1 [...]

Stephen Crooke, Ph.D., is a postdoctoral research fellow in the Vaccine Research Group within the Mayo Clinic Department of General Internal Medicine.   Stephen Crooke, Ph.D., retrieves samples to test as part of Mayo Research Group’s Zika peptide vaccine study. As a postdoctoral research fellow in the Mayo Clinic Vaccine [...]

By Jay Furst Low vitamin B12 levels can worsen some symptoms of Parkinson's disease, especially postural instability and cognitive impairment, which can lead to falls and injuries, researchers say. Lower vitamin B12 levels also are associated with higher Hoehn-Yahr stage, the tool for assessing disease severity, and neuropathy in Parkinson's [...]

Regenerative medicine is redefining clinical care—going beyond disease symptom management to addressing the underlying cause of disease to restore health. Regenerative care is expected to represent 10% of all health care in the next decade. Yet, education in regenerative medicine lags behind scientific and clinical advances. This threatens to leave physicians-in-training ill-equipped [...]

By Jay Furst Computed tomography (CT), which uses specialized X-rays to create images of areas inside the body, has revolutionized medicine in the nearly 50 years since it became commonly available. From kidney stones to cancer, CT has become an indispensable diagnostic tool. In 1980, an estimated 3 million CT [...]

T-cells are having a moment. Well maybe not like Game of Thrones is having a moment, but as stars of the cancer treatment, immunotherapy, T-cells are definitely cool. But what is a T-cell? And how can you get one? Good news! Your body makes T-cells for you, a lot of [...]

Bithika Thompson, M.D., an endocrinologist at Mayo Clinic in Phoenix, and M. Adela Grando, PhD., a biomedical informaticist at Arizona State University, recently teamed up on a health care research project that could transform the way individuals manage their diabetes. Type 1 diabetes is a chronic disease that affects more [...]

Mayo Clinic Ventures commercializes technologies to benefit patients while generating revenue to support clinical practice, research and education. Thanks in part to licensing and partnership efforts, 2018 was a banner year for Mayo Clinic Ventures' financial performance. By Kate Stober Mayo Clinic has a long and storied history of firsts [...]

According to the International Osteoporosis Foundation, more than 200 million people worldwide suffer from osteoporosis, or insufficient regeneration of bone tissue and fragile bones. At least 40% of postmenopausal women and 15-30% of older men will sustain one or more fractures due to fragility. Osteopenia, a lesser form of bone [...]

Left: Peter Grahn, Ph.D., and Megan Gill, D.P.T.. Right: Megan Gill, D.P.T., (seated) assists Jered Chinnock as part of a clinical trial to determine if spinal cord circuitry can be modulated with electrical stimulation and rehabilitation to restore function lost to paralysis. Mayo Clinic has challenged its researchers to transform [...]

Drs. Tatum (left) and Quinones-Hinojosa using brain mapping during a procedure. Surgeons in the operating room must achieve a delicate balance when removing a brain tumor: eradicate as much of the cancer as possible, and avoid injury to parts of the brain responsible for motor control, speech, and more. For [...]

2019 Regenerative Medicine and Surgery Selective Bringing regenerative medicine to more patients requires highly skilled medical providers. During a recent weeklong educational course, 42 medical and graduate students were immersed in regenerative medicine at Mayo Clinic. The Regenerative Medicine and Surgery Selective introduces students to regenerative medicine and surgery by [...]

Mayo Clinic’s CT Clinical Innovation Center recently released the first-ever quantitative Stone Analysis Software (qSAS) for characterizing renal stones from CT images. The product is available at no charge for research use through a software sharing agreement. Cynthia McCollough, Ph.D., Division of Medical Physics, Department of Radiology at Mayo Clinic [...]

Every year the American Society of Clinical Oncology (ASCO) hosts a gathering of cancer researchers and clinicians from around the world to teach and learn from each other, sharing their research and innovations in patient care. ASCO's mission is "conquering cancer through research education, and promotion of the highest quality [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research- and research education-related news releases from the past month. It also connects readers to additional resources of relevance. Read on for more information from Mayo Clinic Research. Mayo experts to present findings at Digestive Disease Week 2019 [...]

Amyloidosis is a rare disease that occurs when a substance called amyloid builds up in your organs. Amyloid is an abnormal protein that is produced in your bone marrow and can be deposited in any tissue or organ. Hereditary amyloidosis (familial amyloidosis) is an inherited disorder that often affects the [...]

AcademyHealth's Annual Research Meeting, June 2-4, 2019, in Washington, D.C., showcases "Today's research driving tomorrow's outcomes." It is an ideal venue to share research findings from across the continuum of health care delivery. The Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery [...]

Regenerative science has advanced next-generation technologies from the research bench to potential clinical care options. But in the rigorous development of patient therapies, it is critical to validate the safety and efficacy of regenerative solutions. Shane Shapiro, M.D. Shane Shapiro, M.D., medical director of the Regenerative Medicine Therapeutics Suites on [...]