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August 7, 2012

Do you have Barrett's Esophagus? Volunteers sought for Research Study.


This is a picture of many people on exercise bikes.The Cancer Prevention Network (CPN) is inviting people, 18 years and older, who have been diagnosed with Barrett’s esophagus to take part in a study to learn if and how metformin affects you and your esophagus. Specifically, they are trying to learn if this medication may have an effect on your risk for getting cancer of the esophagus.

What is metformin?

Metformin is approved by the Food and Drug Administration (FDA) for the management of Type 2 diabetes. It has not been approved for the treatment of Barrett’s esophagus or the prevention of esophageal cancer. Therefore, the use of metformin in this study is considered investigational.

What does this study involve?

If you decide to participate, you will have three study visits. You will have a physical exam, give blood samples, and have two esophagogastroduodenoscopy (EGD) procedures. The EGD helps us look at the inside of your esophagus and stomach. You will be in this study for a total of five months.

Are there any risks involved?

If you choose to participate, you will be at risk for side effects from the medication and EGD procedures. Some of the common side effects are headache or muscle pain, weakness, nausea, abdominal pain and stomach upset. More possible side effects will be discussed with you before you decide to participate.

Will I get any benefit from being in the study?

If you agree to be in this study, there may or may not be any direct medical benefit to you. We hope what we learn from this study will benefit others at risk for esophageal cancer in the future.

If you finish this study, you will be compensated for your time.

Who can I contact for more information?

If you have any questions, please call (507) 284-1602.


This study is funded by the National Cancer Institute and conducted by the Cancer Prevention Network (CPN).  CPN has over 35 sites throughout the United States and Canada. Our goal is to learn how to prevent cancer before it starts.

There may be a CPN site close to you so call now and become involved in a clinical research study today!

For more information about CPN, check out our website at

Tags: cancer, Cancer Prevention Network, EGD, esophagus, Mayo Clinic, Paul Limberg, research, study, Uncategorized


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