Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

April 30, 2013

Crohn's Disease Activity Index (CDAI) & Patients with Irritable Bowel Syndrome (IBS) – IBD in the News


Edward Loftus Jr., M.D., a gastroenterologist at Mayo Clinic specializing in the care and evaluation of patients with IBD, discusses the implications of recent article published in Alimentary Pharmacology & Therapeutics that found a group of patients with IBS to have higher CDAI scores than patients with Crohn’s disease.

Specifically, Dr. Loftus mentions:

- Because signs of Crohn’s disease are neither sensitive nor specific, clinicians can’t rely on symptoms alone to make treatment decisions.

- It is important to support the CDAI score with endoscopic measures, CRP levels, or measure of inflammation in the stool.

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Tags: Crohn's disease, Edward Loftus, Findings, gastroenterology, IBD, inflammatory bowel disease, ulcerative colitis

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