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July 17, 2018

Researching gene therapy for liver diseases: Joseph Lillegard, M.D., Ph.D.

By Jennifer Schutz

Joseph Lillegard, M.D., Ph.D., is a Regenerative Medicine Minnesota research grant recipient. He is researching gene therapy to fight inborn errors of metabolism of the liver, primarily Hereditary Tyrosinemia Type 1 (HT1), a metabolic disorder caused by an enzyme deficiency. HT1 is a genetic disorder that can lead to liver and kidney failure, and is fatal without treatment. There is no cure. This project aims to develop a lentivirus-mediated gene therapy to treat multiple inborn errors of liver metabolism, with the research in HT1 serving as a model for future studies of other rare liver diseases.

Dr. Lillegard is a supplemental consultant at Mayo Clinic and a pediatric general and thoracic surgeon at Children's Minnesota.

Learn more about Dr. Lillegard’s research in the video below:

 

Visit the Center for Regenerative Medicine Blog for more information on regenerative medicine at Mayo Clinic.

Tags: Awards, Center for Regenerative Medicine, Joseph Lillegard, People, regenerative medicine, Regenerative Medicine Minnesota, stem cells

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