Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

July 19, 2018

A clearer picture: new imaging technologies advance diagnosis, individualized care

By Susan Buckles

New imaging technologies are advancing diagnosis and individualizing care. Imaging tests – such as a CT scan or MRI – are essential tools that health care providers use to answer complex and challenging questions.

Gabriel Krestin, M.D., Ph.D.

Gabriel Krestin, M.D., Ph.D., a radiologist and researcher, is at the forefront of new efforts to apply cutting edge imaging technologies that can detect subtle biological and molecular changes to more accurately diagnose and treat disease. At this year’s Individualizing Medicine Conference: Advancing Care through Genomics, Dr. Krestin will discuss his work on integrating new imaging methods to identify objective, quantitative, and standardized features available in digital images – called imaging biomarkers – that can be important to predict complex diseases, their outcome and monitor treatment. The conference will be held September 12 and 13 at the Mayo Civic Center.

New techniques offer a better view of disease

Historically, imaging has been used by physicians to visualize anatomy without even picking up a scalpel. Within the past several decades new imaging methods are providing a better look at the size, location and biological characteristics of normal and disease processes within the body.

“New imaging techniques offer important information about the physiology, organ function, and biological and molecular functions, allowing us to predict disease long before symptoms appear,” explains Dr. Krestin.


Sponsored by the Brandt Family Scholars Fund, the Early Career Investigators in Precision Medicine Scholarship Program is looking for early-career investigators with an interest in individualized medicine. Awardees will present their research-based or challenging case as a poster and/or concurrent platform presentation at the Individualizing Medicine Conference.

Deadline to apply is July 30 at Abstract Scorecard.

The Brandt Family Scholars Fund seeks to encourage and support early career investigators in precision medicine discovery or translation. See the Individualized Medicine Blog for past awardee information.

These imaging biomarkers are playing a key role in precision medicine research and practice, helping to reveal subtle differences that can indicate the best individualized approach for choosing the right therapy.

“This “deep imaging phenotyping” is at the basis of the emerging field of radiomics, allowing us to play an increasing role in prediction of disease, of outcomes and of therapy response. Using aartificial intelligence and computational methods, we can integrate imaging data with genomic, clinical and environmental information to provide new knowledge to guide patient care. The key to the success of this new ‘data driven medicine’ approach is collaboration among multiple specialists to interpret these results and then develop individualized treatment plans for patients,” says Dr. Krestin.

An opportunity to learn from a leader

Kiaran McGee, Ph.D., director of the Center for Individualized Medicine Imaging Biomarker Discovery Program, notes that Dr. Krestin’s research has focused on imaging of abdominal organs and cardio-vascular diseases, molecular imaging and population imaging.

Kiaran McGee, Ph.D.

“Dr. Krestin has worked at many leading academic medical institutions and serves on many advisory boards, allowing him to have his finger on the pulse of advances in radiological imaging and how these new techniques can be applied to improve personalized patient care,” says Dr. McGee.

Dr. Krestin is a professor of Radiology and Chairman of the Department of Radiology and Nuclear Medicine at Erasmus MC, University Medical Center Rotterdam, in the Netherlands. In 2017, he was elected to the National Academy of Science, Engineering and Medicine (US). He has authored more than 400 publications and over 70 book chapters.


Register now for the Individualizing Medicine Conference, Sept. 12-13, 2018, in Rochester, Minnesota.

Tags: biomarkers, Center for Individualized Medicine, Education, Events, individualized medicine, Individualizing Medicine Conference, Innovations, Kiaran McGee, People, radiology, republished

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