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Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

August 16, 2018

Investigating gene therapy strategies for obesity: Ping Chen, Ph.D.

By Jen Schutz

The major challenge in treating obesity is not just losing weight, but preventing weight from coming back. With a research grant form Regenerative Medicine Minnesota, Ping (Vicky) Chen, Ph.D., Mayo Clinic research associate,  is studying a new treatment strategy using gene transfer therapy to safely target brain mechanisms that control hunger and energy output.

Dr. Chen’s previous research in mice found that gene transfer of a well-tolerated liver enzyme could revolutionize clinical treatment of obesity, making it easier for obese patients to lose weight safely and minimize later weight gain. Her research on the mechanism behind weight control will further determine if this approach might succeed in humans. Researchers expect the effects to correlate positively with reduction in ailments such as diabetes, metabolic syndrome and fatty liver disease.

Learn more about Dr. Chen’s research:

Visit the Center for Regenerative Medicine Blog for more information on regenerative medicine at Mayo Clinic.

Tags: Awards, Center for Regenerative Medicine, medical research, obesity, People, Ping Chen, regenerative medicine, Regenerative Medicine Minnesota, republished, research

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