Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

September 24, 2019

Research for infants with HLHS moves forward

By Jennifer Schutz

Hypoplastic left heart syndrome (HLHS) is a complex and rare heart defect present at birth in which the left side of a child's heart is severely underdeveloped. At Mayo Clinic, physicians and researchers in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome are looking for ways to delay or even prevent heart failure for people with HLHS.

The program has launched clinical trials using a patient's own stem cells with the goal of strengthening the heart. One of the clinical trials uses stem cells collected from a baby's own umbilical cord blood banked with the program. The stem cells are injected into the baby's heart during the second of three surgeries.

The phase I clinical trial is the first research monitored by the Food and Drug Administration that demonstrates the potential of regenerative therapy for HLHS through collecting, processing and injecting an infant's own stem cells directly into the heart at the time of surgery.

Stem cell therapy for HLHS is one of several approaches the Center for Regenerative Medicine is studying that goes beyond disease management to search for and discover therapies that support the body in repairing, regenerating and restoring itself to a state of well-being.

Read the full news release on the Mayo Clinic News Network.

This story was originally published on the Center for Regenerative Medicine blog.

###

STAY CONNECTED — Advancing the Science

  • If you enjoyed this article, you might want to subscribe for regular updates.
  • If you want to share this story with friends, social media links are at the top of the article.
  • And if you want to see other recent stories on the blog, the index page is a great place to start.

Tags: Center for Regenerative Medicine, clinical trials, HLHS, hypoplastic left heart syndrome, pediatric cardiology, Progress Updates, stem cells

Please login or register to post a reply.
Contact Us · Privacy Policy