Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

December 31, 2020

Mayo Clinic Research in the news — 12/31/2020

By Elizabeth Zimmermann
graphic art newspaper laptop

Following are headlines and story excerpts highlighting Mayo Clinic Research and research faculty the last part of December 2020. Read on for advancements and information on esophageal cancer, antibiotic risks for babies and toddlers, a Mayo inductee into the Fellows of the National Academy of Inventors, and several other stories, including a slew of COVID-19 related articles.

NOTE: The next summary post will be Monday, Jan. 11, 2021. Happy New Year!


Are high-protein diets heathy? Here's what you need to know

Today, 12/30/2020

Can you eat too much protein? While the macronutrient is an essential part of any diet, dietitians say quality is just as important as quantity.

A high-protein diet is one where you’re eating a higher amount of protein each day than is recommended by dietary guidelines, Katherine Zeratsky, a registered dietitian at the Mayo Clinic in Rochester, Minnesota, told TODAY.

According to the Institute of Medicine’s dietary reference intake recommendations, adults should consume 0.8 grams of protein daily per kilogram of body weight. In a balanced diet, that means protein should account for anywhere between 10 and 35% of all calories consumed.

For an adult who weighs 150 pounds that comes out to just over 54 grams of protein a day to meet that recommended intake. Getting more protein than that per day would be considered a higher-protein diet, Zeratsky explained. “It’s dependent on the individual and their body size.” …


Incidence of Esophageal Adenocarcinoma is Increasing in Younger Adults

American Association for Cancer Research (news release), 12/16/2020

Esophageal adenocarcinoma is occurring more frequently in adults under age 50, and these younger adults are more likely to be diagnosed at advanced stages, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. …

“Patients who present with late-stage esophageal cancer typically have poorer outcomes than those with early-stage disease. As such, it is important to understand the epidemiology of esophageal cancer to target our screening strategies,” said the study’s corresponding author, Prasad G. Iyer, MD, MSc, professor of medicine in the Barrett’s Esophagus Unit, Division of Gastroenterology and Hepatology at the Mayo Clinic in Rochester, Minnesota. …


Antibiotics before age 2 tied to range of health problems

BabyCenter, 12/21/2020

Children given antibiotics before age 2 are at higher risk for developing a range of long-lasting health conditions, a Mayo Clinic study found. The research doesn't prove that antibiotics cause the health problems. Antibiotics can be critical in treating certain infections in children, but parents should not demand pediatricians to prescribe them unnecessarily.


New leader kicks off next phase of Destination Medical Center Initiative

MinneInno (sponsored content), 12/22/2020

The largest public-private economic development partnership in Minnesota history marks a significant milestone on Jan. 4, when Patrick Seeb officially steps into the role of executive director of the Destination Medical Center Economic Development Agency, following the retirement of Lisa Clarke.

Clarke led the $5.6 billion effort, known as DMC, for its formative first five years. Her charge was ambitious: leverage the strength of Mayo Clinic to harness private development and public infrastructure funding in a coordinated effort that would transform the city of Rochester and bolster the surrounding Olmsted County and the state. …

The initiative spans eight core areas: arts, culture and entertainment; livable city; hospitality and convention; research and technology; sports, recreation and nature; learning environment; health and wellness; and transportation. There are multiple projects within each area, all of which are guided by a 700-page, 20-year development plan.


Numerous Indian American Researchers Named 2020 Fellows of National Academy of Inventors

India West, 12/21/2020

The National Academy of Inventors Dec. 8 announced its 175-person cohort of 2020 Fellows, including several Indian Americans and South Asian Americans among the group of global inventors.

Among the Fellows were Ananth Annapragada of the Baylor College of Medicine; Samuel of the Minnesota-based Mayo Clinic; Bir Bhanu of U.C. Riverside; Venkat Bhethanabotla of the University of South Florida; V. Chandrasekar of Colorado State University; Ramalingam Chellappa of Johns Hopkins University; Rajesh Dave of the New Jersey Institute of Technology; Anant Madabhushi of Case Western Reserve University; Mitzi Nagarkatti of the University of South Carolina; and Vijaykrishnan Narayanan of Pennsylvania State University.

NOTE: Read the article for more on the recognition, or visit Dr. Asirvatham's research profile to learn about his research.


New guidelines call for less use of surgery to treat heart valve disease

Petoskey News-Review (via American Heart Association), 12/22/2020

People with heart valve disease have a growing number of treatment options that could allow them to avoid surgery except in the most severe cases, according to new guidelines.

The recommendations, meant to advise health care providers and developed jointly by the American Heart Association and American College of Cardiology, call for the use of less invasive treatment for conditions that make it difficult for heart valves to open and close normally, disrupting heart blood flow. …

NOTE: Read article for more on the guidelines, including comments from guideline writing committee co-chair Rick Nishimura, M.D., a Mayo Clinic cardiologist. Also note another article from Cardiology Today: Valvular heart disease guideline addresses less-invasive options, shared decision-making.


ELAINE-2 Trial Could Establish the Actionability of ESR1 in HR+/HER2- Breast Cancer

OncLive, 12/21/2020

Matthew P. Goetz, MD, discusses ongoing research in the setting of ESR1-mutant, ER–positive, HER2-negative metastatic breast cancer.

NOTE: Read article for Dr. Goetz's interview on this research as well as other studies presented at the 2020 San Antonio Breast Cancer Symposium.


COVID-19 of course has its own substantial share of news coverage, and Mayo's research and faculty are well represented. Here is an abbreviated list of recent headlines and links to the associated stories.

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Tags: antibiotic, Barrett's esophagus, breast cancer, clinical trials, Destination Medical Center, epidemiology, esophageal cancer, heart disease, hereditary cancer, Innovations, Katherine Zeratsky, Matthew Goetz, News, News of the Week, pediatric research, People, Prasad Iyer

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