Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.
Being patient, 1/8/2021
Carolee Lee of WHAM! (Women’s Health Access Matters) and Michelle M. Mielke at the Specialized Center for Research Excellence on Sex Differences at Mayo Clinic examine the consequences of ignoring gender and biology in Alzheimer’s research — and the pivotal importance of broad lifespan research.
NOTE: More information is also available about Dr. Mielke and the Mayo Clinic Specialized Center of Research Excellence (SCORE) on Sex Differences.
Health Imaging, 1/8/2021
Patient health data has become a valuable commodity, helping researchers develop artificial intelligence tools, identify and prevent diseases, and discover novel treatments. The proliferation of such data, however, has made it clear that current patient consent approaches are inadequate.
That’s according to a group of radiologists from top institutions across the U.S., who recently argued that trust between patients and providers is key to truly realizing the power of patient health information. They called on their field to help develop a new patient-centered approach for data consent, in a Jan. 1 opinion piece published in JACR.
“As radiologists, we should acknowledge that we must become more sophisticated about both the technology and business models of sharing imaging data,” Amy L. Kotsenas, MD, chair of clinical digital imaging at the Mayo Clinic’s Department of Radiology, and colleagues wrote. …
Yanyan Lou, MD, PhD, highlighted the role of atezolizumab, durvalumab, pembrolizumab, and nivolumab and how they have demonstrated improved survival in combination with etoposide and platinum in untreated extensive-stage small cell lung cancer, cementing checkpoint inhibition plus chemotherapy as a frontline standard.
Yujie Zhao, MD, PhD, highlights molecular testing and how it's a critical component of the treatment selection process in lung cancer, as a host of effective drugs have since been developed to target alterations such as ALK, ROS1, and RET.
NOTE: Dr. Zhao is an internist oncologist at Mayo Clinic.
American Journal of Managed Care – podcast, 1/6/2021
Pain is a subjective response with multiple features and components, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.
NOTE: You can watch the video on the site, or read the transcript of Dr. Porreca's interview.
Healio News, 1/4/2021
Use of palliative care services among inpatients with pulmonary arterial hypertension in the United States increased from 2001 to 2017, with a significant rise in the past decade, researchers reported in Chest.
“Experts recommend incorporation of palliative care services into disease management, but there is little data regarding the utilization of palliative care services among patients with PAH,” Hilary M. DuBrock, MD, from the division of pulmonary and critical care medicine at the Mayo Clinic in Rochester, Minnesota, told Healio. “Our study is important as it provides insight into the current state of palliative care utilization in patients with PAH and also highlights specific disparities that exist regarding use of palliative care services across the country.” …
Cancer Network, 1/6/2021
In addition to a concerning trend of increased rates of esophageal adenocarcinoma noted over the last 4 decades, this study also found that the proportion of those with advanced disease at presentation continues to rise for patients younger than age 50.
… “Patients who present with late-stage esophageal cancer typically have poorer outcomes than those with early-stage disease. As such, it is important to understand the epidemiology of esophageal cancer to target our screening strategies,” corresponding author, Prasad G. Iyer, MD, MSc, professor of medicine in the Barrett’s Esophagus Unit in the Division of Gastroenterology and Hepatology at the Mayo Clinic in Rochester, Minnesota, said in a press release.…
Ahram Online, 1/5/2021
… Researchers at the Mayo Clinic concluded that religious involvement and faith are associated with better health, longevity, coping skills, anxiety, and depression.
Religious people have higher self-esteem and better psychological adjustment. …
NOTE: Read one of the related research papers in Mayo Clinic Proceedings
All patients with advanced lung cancer should undergo genetic testing, both in the tissue and in the blood, to identify targetable mutations, according to Rami Manochakian, MD. Although this is understood to be best practice, several barriers still need to be overcome to ensure this testing is done and the results can be used to inform the optimal approach for each individual patient. …
NOTE: Read Dr. Manochakian's full interview online.
Tags: Alzheimer's disease, Amy Kotsenas, artificial intelligence, Barrett's esophagus, consent, COVID-19, data science, esophageal cancer, Findings, Frank Porreca, gene mutation, genetic testing, Hilary DuBrock, lung cancer, Mayo Clinic Proceedings, Michelle Mielke, migraine, molecular testing, News, News of the Week, palliative care, patient experience, patient safety, Prasad Iyer, Progress Updates, pulmonary and critical care medicine, radiology, Rami Manochakian, women's health, Yanyan Lou, Yujie Zhao
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