Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

March 22, 2021

Mayo Clinic Research in the news — 3/22/2021

By Elizabeth Zimmermann

News including Mayo Clinic research and research expertise this week covered a wide range of topics, including genetic testing to inform prescribing blood thinners and therapies for bile duct and gall bladder cancers. A number of women's health related articles highlighted Mayo Clinic research, there were some arguments for naps, and the ever present COVID-19 content.

Genetic Testing Could Help Clinicians Prescribe Blood Thinners

Health IT Analytics, 3/19/2021

Genetic testing can help providers identify the appropriate anti-platelet drugs for patients, leading to enhanced efficacy and fewer side effects, according to a study published in JACC: Cardiovascular Interventions.

NOTE: Read article for more on the study findings, and comments from Naveen Pereira, M.D., Mayo Clinic cardiologist and study first author, as well as Richard Weinshilboum, M.D., director, Mayo Clinic's Center for Individualized Medicine.

Genomic Testing Offers New Therapy Options for Hepatobiliary Cancers

CURE, 3/17/2021

NOTE: This patient-centered story relays current science and genome-informed therapies for gall bladder and bile duct cancers. It includes comment from Lewis Roberts, M.B., Ch.B., Ph.D., a Mayo Clinic gastroenterologist

The Options for Managing Menopause

Medical Daily, 3/18/2021

For those women who have yet to experience the joys of menopause, a few remarks on what you might expect. Some women drench their sheets from sweat on a regular basis; others have difficulty controlling emotions; and then there are others who initiate divorce during the menopause years.

… Menopause can last a long time. According to Stephanie Faubion, MD, medical director of The North American Menopause Society and director of the Center for Women's Health at the Mayo Clinic, it can last up to 10 years. “We now know that the mean duration of symptoms is seven to nine years,” and for a third of women, hot flashes can endure for up to a decade, she said.

NOTE: Read the article for more on menopause and from Dr. Faubion.

Contrast-enhanced mammography for breast cancer in women with augmented breasts

Science CODEX, 3/18/2021

According to ARRS' American Journal of Roentgenology (AJR), contrast-enhanced mammography (CEM) showed concordance with MRI in women with newly diagnosed breast cancer and breast augmentation.

Noting that CEM has not been investigated in women with breast augmentation, Molly Carnahan and her Mayo Clinic team in Phoenix, AZ, concluded, "the findings suggest a possible role of CEM for staging in women with breast augmentation and contraindication or limited access to MRI."

NOTE: Read the article for more from Dr. Carnahan's study.

Hypertension Symptoms Often Mistaken for Menopause in Middle-Aged Women

Everyday Health, 3/15/2021

One in 2 women may develop hypertension, or high blood pressure, before age 60. But a group of European doctors warn that many of these women may miss out on needed treatment to help prevent events like heart attacks and strokes because their hypertension symptoms are chalked up to menopause. 

NOTE: The article includes expert commentary from Stephanie Faubion, M.D., director, Mayo Clinic Center for Women's Health.

Clinical practice and research yields valuable data for management of uterine fibroids

Contemporary OB/GYN, 3/15/2021

“New studies are showing significantly increased risks of cardiovascular disease, weight gain and mood disorders, even with bilateral ovarian conservation,” Elizabeth A. Stewart, MD, told Contemporary OB/GYN.

There have been many valuable lessons learned from clinical practice and research on uterine fibroids (UFs), according to a presenter at the 2021 Fibroid Summit.

For example, although hysterectomy is the most common gynecologic procedure, “many clinicians are not aware of data linking hysterectomy to long-term health risks, even when both ovaries are conserved,” said Elizabeth A. Stewart, MD, a professor of ob/gyn and surgery at Mayo Clinic and Mayo Clinic Alix College of Medicine in Rochester, Minnesota. …

NOTE: Read article for more from Dr. Stewart's presentation.

Amrika Ramjewan shares lessons on healthcare at US-based Mayo Clinic

Trinidad and Tobago Newsday, 3/18/2021

NOTE: This article is an interview with Amrika Ramjewan, a senior health systems engineer at Mayo Clinic.

Weight loss leads to worse outcomes in women with HER2+ early-stage breast cancer

Contemporary OB/GYN, 3/18/2021

A team of international researchers partnered with the National Cancer Institute and Mayo Clinic to conduct a research opportunity that led to unexpected findings.

… Published last month in the Journal of the National Comprehensive Cancer Network, the study concluded that weight loss of 5% or greater over 2 years negatively impacted clinical outcomes. Weight gain during that same time did not affect survival rates.…

Adherence to asthma biologic therapy higher than inhaled corticosteroids

Healio News, 3/19/2021

In a new study, adherence to asthma biologic therapy was higher than adherence to inhaled corticosteroids among adults with asthma. Researchers reported that adherence to asthma biologics was weakly associated with prior adherence to inhaled corticosteroids.

NOTE: Read article for more on the study, which used the OptumLabs Data Warehouse, as well as comments from first author Jacob Maddux, M.D., a Mayo Clinic resident fellow in Allergy and Immunology.

A Biological Explanation for How Napping Enhances Learning and Memory

Neurology Today, 3/18/2021

New research found an increase in left hippocampal activity following daytime naps, which correlated with increased sleep spindles and improved memory encoding performance.

… Diego Z. Carvalho, MD, a sleep physician, and researcher at the Mayo Clinic in Rochester, MN, added that good sleep quality is associated with memory consolidation and protects against cognitive decline.

NOTE: Read the article for more on the research as well as commentary from Dr. Carvalho.

Mayo Clinic expertise shines light on COVID-19


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Tags: antiplatelet, asthma, bile duct cancer, breast cancer, COVID-19, Diego Zaquera Carvalho, Elizabeth Stewart, Findings, gall bladder cancer, gastroenterology, genetic testing, genetics, genomics, hypertension, Jacob Maddux, Lewis Roberts, mammogram, menopause, Molly Carnahan, National Comprehensive Cancer Network, Naveen Pereira, News, News of the Week, OptumLabs, People, Progress Updates, Richard Weinshilboum, sleep medicine, Stephanie Faubion, steroids, uterine fibroids, weight loss, women's health

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