Catch up on some of the news about Mayo Clinic's research and faculty experts. Among the topics covered are artificial intelligence, women's sexual health, genetic implications for several conditions, and COVID-19.
… Specifically, the algorithm, created by physicians at Mayo Clinic, found Maercklein had an 81.49% probability of experiencing A-fib, a quivering or irregular heartbeat that can lead to heart failure and stroke. Just days later, after Maercklein agreed to participate in a research study, a wearable Holter monitor recorded an episode of A-fib while he was walking on a treadmill.
Healio News, 4/22/2021
“Although several colorectal cancer screening methods have been shown to reduce colorectal cancer, nearly one-third of eligible adults in the United States have never completed colorectal cancer screening and colorectal cancer screening continues to be underutilized," Xuan Zhu, PhD, senior health services analyst at the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, and colleagues wrote. "Recommended colorectal cancer screening modalities vary with respect to safety, efficacy and cost. Better understanding of the factors that influence patient preference is, therefore, critical for improving population adherence to colorectal cancer screening." …
Healio News, 4/24/2021
Lamassu Pharma announced the development of its lead therapeutic compound, RABI-767, may fulfill the unmet clinical need for the treatment of patients with pancreatitis, according to a press release.
RABI-767 is a novel small molecule lipase inhibitor that is injected directly into the pancreas; in preclinical studies, it decreased the breakdown or release of unsaturated fats and saturated fats during acute pancreatitis attacks. The value of this therapeutic was underscored by recent Mayo Clinic research that found the rapid breakdown of unsaturated fat can worsen the course of severe acute pancreatitis leading to increased toxicity, organ failure and death.
… “Wildfires cause particulate matter to circulate in the air which could settle on the skin, similarly to other airborne irritants,” Dr. Dawn Marie Davis, a professor of dermatology and pediatrics at the Mayo Clinic, said in an email. “The skin may be negatively impacted by exposure to wildfire smoke.”
… Burnout was rearing its ugly head long before we were hit by the COVID shitstorm. The pandemic was merely an accelerant. A 2018 study in the journal Mayo Clinic Proceedings found that the rate of "overall burnout” among the general U.S. workforce was 28%.
IFL Science, 4/21/2021
… A new study suggests that poor quality sleep may lead to problems in the bedroom, namely in regards to female sexual dysfunction.
Scientists at the Mayo Clinic asked over 3,400 women in the US about their sleep patterns and sexual behavior through the Female Sexual Function Index, a 19-point self-report that investigates things such as sexual desire, arousal, lubrication, orgasm, satisfaction, and pain during sex. The study was published in the journal Menopause this week.
Related article: You'll Have More Sex If You Do This for an Extra Hour a Day
… Charanjit Rihal, MD (Mayo Clinic, Rochester, MN), who co-authored another meta-analysis of genetics-guided antiplatelet therapy published last month, told TCTMD there is now enough evidence to support changing the guidelines. All of the data “confirms that a smart approach to antiplatelet therapy may be the best thing for the community to gravitate toward,” he said. “It’s not the be all and end all, but it is an important determinant of outcomes. . . . I believe that all the evidence is converging, [and] that we as clinicians should begin to pay attention.”
Becker's Spine Review, 4/19/2021
A Rochester, Minn.-based Mayo Clinic study led by Kade McQuivey, MD, found that 97 percent of orthopedic surgery residents experience procedural-related musculoskeletal pain. Six notes …
Reuters Fact Check, 4/21/2021
… Dr. Matthew Sztajnkrycer, Emergency Medicine Physician at the non-profit academic medical center — the Mayo Clinic agreed, telling Reuters via email, “A major role of skin is to protect the body from infection […] Burns are very prone to infection and salmonella infection may be catastrophic.” Sztajnkrycer went on to explain how a recent medical study in Iran did find that patients whose burns were treated with an egg white-based ointment healed slightly faster, however he says this is “very different than simply placing raw egg white on a fresh burn” as this was a “very controlled study” where many patients were “excluded due to risk factors” and it was “performed by specially trained surgeons at a regional burn center.”
Becker's Hospital Review, 4/20/2021
Family genes play a significant role in the development of colon cancer, according to a study recently published in Clinical Gastroenterology and Hepatology.
Researchers from Rochester, Minn.-based Mayo Clinic used a sequencing panel that included more than 80 cancer-causing or predisposing genes to test 361 colorectal cancer patients who received care at Mayo Clinic cancer centers between April 1, 2018, and March 31, 2020. Standard sequencing panels for colorectal cancer include a maximum of just 20 genes, researchers note.
Monthly intravenous (IV) infusions of PRX004 were generally safe and well tolerated at all dose levels tested, with 233 separate infusions given in total and each patient receiving between 3 and 17 infusions throughout the study. …
Commenting on the study for Medscape Medical News, Morie Gertz, MD, professor of medicine at Mayo Clinic, Rochester, Minnesota, who was not involved in the current work, said this was a completely new approach to treatment. "PRX0004 represents a monoclonal antibody that binds to the amyloid fibrils and stimulates phagocytosis dissolving existing amyloid deposits," he explained. "This phase 1 trial was primarily designed for toxicity; however, patients showed improvement in neurological impairment and the echocardiogram also improved in 7 patients," he noted.
Common wisdom is that a calorie is a calorie—for example, 500 calories worth of vegetables is the same as 500 calories worth of ice cream, they just have very different nutrient profiles. But a new study is challenging that assumption when it comes to almonds.
Research published in Mayo Clinic Proceedings looked at 22 men and women with high cholesterol who undertook a series of dietary interventions over a three-month period. …
NOTE: Read the article to for the findings.
If your morning routine involves tossing down a handful of dietary supplements in vague hopes of boosting your energy or warding off illness this week or disease down the line, you might want to dial back and rethink your approach—especially if you’re of the mindset that you don’t need to discuss your supplements regimen with your doctor.
Here’s why: Although dietary supplements can play a role in remedying a vitamin deficiency or nutritional imbalance, they’re generally unnecessary for people who have a well-rounded diet, and supplements might even pose health risks, Donald Hensrud, M.D., MPH, director of the Mayo Clinic Center Healthy Living Program, tells SELF. …
NOTE: Read the article for more from Dr. Hensrud.
The Mayo Clinic College of Medicine and Science includes five schools:
Tags: About, AFib, amyloidosis, antiplatelet, artificial intelligence, atrial fibrillation, Center for the Science of Health Care Delivery, Charanjit Rihal, colorectal cancer, COVID-19, Dawn Marie Davis, dermatology, Donald Hensrud, emergency medicine, Findings, genetics, heart failure, hereditary cancer, Innovations, integrative medicine, Kade McQuivey, Matthew Sztajnkrycer, Mayo Clinic College of Medicine and Science, Mayo Clinic Proceedings, Morie Gertz, News, News of the Week, orthopedic surgery, orthopedics, pancreatitis, physician burnout, Progress Updates, sleep medicine, Stephanie Faubion, stroke, supplements, wearable technology, women's health, Xuan Zhu