By Jay Furst McArdle's sign, a distinctive muscle weakness that affects patients with spinal cord disease, was first noted more than 30 years ago. The namesake of the "sign," M.J. McArdle, was a professor of neurology in London, and one of his patients with advanced multiple sclerosis needed to extend his neck and tip his head [...]

— Yale University Office of Public Affairs & Communications Yale University and Mayo Clinic have been awarded a grant for up to $5.3 million over two years by the U.S. Food and Drug Administration (FDA) to study patients’ experiences with pain and use of opioids prescribed for acute pain. This project is part of the Center of Excellence in Regulatory [...]

Hypoplastic Left Heart Syndrome (HLHS) is a rare disease that affects approximately 1 of every 4,300 babies every year.  HLHS is a congenital heart defect in which the left side of the heart is underdeveloped. It occurs during fetal growth when the baby's heart is developing. Without immediate intervention after birth, [...]

By Barbara J. Toman By definition, personalized medicine requires diversity. One-size-fits-all doesn't work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic's Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo's medical research. Sangre [...]

By Nicole Sisk Artificial intelligence will play a key role in Mayo Clinic's future and that of health care worldwide. The Department of Cardiovascular Medicine is combining artificial intelligence with standard tests to improve patient care. Each year at Mayo Clinic, 250,000 patients have an electrocardiogram, or ECG. It's a common, [...]

From the earliest days, physicians and scientists have flocked to Mayo Clinic from all over the world to learn: Foreign-born physicians in the early days at Mayo Clinic included Donald Balfour, M.D., of Canada, arriving in 1907; Gordon New, M.D., of Canada, 1910; Frank Smithies, M.D., from England in 1910; [...]

Marina Walther-Antonio, Ph.D., has a full plate. An associate consultant in surgical research in the departments of Surgery and Obstetrics and Gynecology at Mayo Clinic in Rochester, she studies the microbiome role in human health and disease, particularly endometrial and ovarian cancer. She also develops technology in her lab, including [...]

Stroke is the leading cause of permanent disability in the U.S., striking nearly 800,000 people each year, according to the Centers for Disease Control and Prevention. In the last decade, there has been preclinical research that led to a small number of early phase clinical trials using mesenchymal stem cells (MSCs) as [...]

Gastrointestinal bleeding is a common side effect for many blood-thinning medications. But new Mayo Clinic research finds that risk is amplified when patients receive more than one blood thinner – especially if they’re 75 or older. The study, published in Clinical Gastroenterology and Hepatology, found patients receiving an anticoagulant drug and [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Racism influences medical students’ decision on practicing in minority or underserved communities, study [...]

By Sharon Rosen Do you have family members who have been diagnosed with gastrointestinal, breast or ovarian cancer? According to a recent Mayo Clinic study, nearly 5% to 10% of these cancers can be hereditary. That’s why it is important to share your family medical history with your physician, who [...]

By Jon Holten Just as aspiring physicians pledge to uphold medical ethics in the Hippocratic Oath, incoming Ph.D. students at Mayo Clinic Graduate School of Biomedical Sciences for the first time recently pledged to uphold biomedical ethics. As part of orientation, 52 students pursuing a doctoral degree in biomedical science started their research [...]

By Adolfo Espitia, Jr., undergraduate public affairs intern Hurricanes Irma and Maria struck back-to-back in Puerto Rico on Sept. 6 and 20, 2017, destroying pharmaceutical manufacturing plants that long supplied Mayo Clinic. Puerto Rico-based factories were the clinic’s single source of an amino acid solution required for preparation of liquid nutrition [...]

Advancements in the field of medical research don't always follow a straight line. Obstacles, challenges and questions arise. When researchers reach an impasse, what can they do? They can start with a new question. If everyone in the room is saying, "Yes, but ...," then it may be time to find someone [...]

By Sharon Rosen Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment [...]

Forefront is the complimentary magazine of the Mayo Clinic Cancer Center. Published in email and online newsletter editions quarterly, Forefront highlights Mayo Clinic’s cutting-edge cancer research and the latest Cancer Center news. The June 2019 issue features: Director’s message: Prioritizing cancer researchFederal cancer research funding is vital to meet growing challenges as the population ages. Predicting [...]

Mayo Clinic Alix School of Medicine launched a Wilderness and Austere Medicine selective to teach students how to provide care for individuals injured in resource-limited and diverse environmental conditions. A unique component of the medical school’s individualized learning is the 25 weeks of “selective” time protected within the first two [...]

In 2010 Peter Grahn, Ph.D., attended an annual research symposium in Minneapolis hosted by the Morton Cure Paralysis Fund. Among the leading spinal cord injury researchers speaking was Mayo Clinic neurologist Anthony Windebank, M.D., the Judith and Jean Pape Adams Charitable Foundation Professor in Neuroscience, who discussed his laboratory’s [...]

By Maria Ly, undergraduate public affairs intern Early diagnosis will ultimately be essential in the management and treatment of Alzheimer’s disease. Examination of Alzheimer’s biomarkers can improve the prediction of short-term memory decline in middle-age and elderly individuals, according to new researchfrom Mayo Clinic. A new diagnostic framework developed in collaboration with [...]

Kenton Kaufman, Ph.D., departments of Orthopedic Surgery and Physiology and Biomedical Engineering at Mayo Clinic in Rochester, is a veteran investigator of limb amputation and prostheses with more than 25 years of experience. He’s on the Medical Advisory Board of Prosthetics 2020, an initiative of the American Orthotic Prosthetic Association. [...]

Mayo Clinic will host the 6th Annual Metastatic Breast Cancer Conference at the Omni Scottsdale Resort and Spa at Montelucia in Scottsdale, Arizona, Sept. 19–20. This program is a joint effort among Mayo Clinic, Baylor College of Medicine, and Theresa's Research Foundation. The Metastatic Breast Cancer Conference was established as an annual medical [...]

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Study finds value in physician-patient outcome assessment process Sometimes a physician thinks the outcome of a [...]

Lately the news has contained many stories of illness or death that could have been prevented by vaccination. Although in 2019 the stories have mostly been about measles, in 2016 it was pertussis, or whooping cough, as it was in 2012, and 2004-2005. The Centers for Disease Control estimates 24.1 million cases of whooping [...]

Stephen Crooke, Ph.D., is a postdoctoral research fellow in the Vaccine Research Group within the Mayo Clinic Department of General Internal Medicine.   As a postdoctoral research fellow in the Mayo Clinic Vaccine Research Group, my research is centered primarily around the use of systems biology approaches to develop a more [...]

By Jay Furst Low vitamin B12 levels can worsen some symptoms of Parkinson's disease, especially postural instability and cognitive impairment, which can lead to falls and injuries, researchers say. Lower vitamin B12 levels also are associated with higher Hoehn-Yahr stage, the tool for assessing disease severity, and neuropathy in Parkinson's patients. While [...]