Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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Sep 16, 2019

Research breathes new air into donor lungs

By Advancing the Science contributor @advancingthescience
By Sara Nick Four hundred: That’s the number of U.S. patients who die each year awaiting a lung transplant, or are removed from the wait list when they become too ill. Now, cutting-edge research underway on Mayo Clinic’s Florida campus aims to save as many of those lives as possible. “We’re [...]
Research breathes new air into donor lungs
Sep 13, 2019

REAL WORLD EVIDENCE in health care improvement

By Elizabeth Zimmermann @elizabethzimmermann
In late 2012 Optum and Mayo Clinic came together to form OptumLabs, an open, collaborative research and innovation center, dedicated to improving patient care and patient value through data-driven health care research, leading-edge data science and strong partner collaboration.  Since that time, approximately 150 collaborative projects have led to peer-reviewed publication, [...]
REAL WORLD EVIDENCE in health care improvement
Sep 12, 2019

Behind the scenes--Mayo Clinic Research

By Elizabeth Zimmermann @elizabethzimmermann
Everything health care has to offer for patients is the result of research and education related to that research. At Mayo Clinic, research drives everything we do, resulting in evidence-based treatments and continuous improvements in the way patients, caregivers and others experience health care. At Mayo Clinic we share information about [...]
Behind the scenes--Mayo Clinic Research
Sep 11, 2019

Targeting therapy to each patient's unique cancer

By Advancing the Science contributor @advancingthescience
Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision [...]
Targeting therapy to each patient's unique cancer
Sep 10, 2019

Mayo fellow already an internationally recognized expert on celiac disease

By Advancing the Science contributor @advancingthescience
Alberto Rubio Tapia, M.D., was a fellowship-trained gastroenterologist in Mexico. He came to Mayo Clinic in 2006 to gain research experience. “My institution in Mexico City, National Institute of Medical Sciences and Nutrition (Salvador Zubiran), has a long tradition in clinical and research training collaboration with Mayo Clinic, so I [...]
Mayo fellow already an internationally recognized expert on celiac disease
Sep 9, 2019

Mayo Clinic Cancer Center Renews National Cancer Institute Research Funding

By Nicole Brudos Ferrara @nicoleferrara
Mayo Clinic Cancer Center has once again successfully renewed its National Cancer Institute (NCI) Cancer Center Support Grant. The grant award provides roughly $28.7 million in funding over five years through 2024, which will mark Mayo Clinic’s 49th year of NCI funding. Mayo Clinic Cancer Center’s NCI designation as a comprehensive [...]
Mayo Clinic Cancer Center Renews National Cancer Institute Research Funding
Sep 5, 2019

If it isn't broken, why fix it? Advancements in multiple myeloma diagnosis.

By Advancing the Science contributor @advancingthescience
The standard laboratory test to diagnose multiple myeloma dates back to the Eisenhower administration. Research at Mayo Clinic spearheaded by David Murray, M.D., Ph.D., and fueled by his experience as an industrial chemist has led to a new assay to screen and diagnose the disease. Lacking in speed and specificity [...]
If it isn't broken, why fix it? Advancements in multiple myeloma  diagnosis.
Sep 4, 2019

Mayo experts provide insights into how genes affect medication response

By Advancing the Science contributor @advancingthescience
By Sharon Rosen Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that [...]
Mayo experts provide insights into how genes affect medication response
Sep 3, 2019

Research News Roundup--August 2019

By Elizabeth Zimmermann @elizabethzimmermann
Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. Read on for recent findings of Mayo Clinic Research: Genetically manipulating protein level in colon [...]
Research News Roundup--August 2019
Aug 28, 2019

Grant supplement opens doors for future cancer researchers in Native American communities

By Advancing the Science contributor @advancingthescience
By Lydia Hansen, Public Affairs undergraduate intern In the summer of 2014, Corinna Sabaque moved over 1,000 miles from her home in the Four Corners area in New Mexico to Rochester, Minn. to complete a 10-week internship in breast cancer research at Mayo Clinic. “Coming to Minnesota was hard,” Sabaque says. “I didn’t know anybody. [...]
Grant supplement opens doors for future cancer researchers in Native American communities
Aug 27, 2019

Community voices guide use of biobank samples in research

By Caitlin Doran @caityrosey
Mayo Clinic supports biobanks—large collections of patient biological samples—near each of its three campuses in Arizona, Florida, and Minnesota, with the goal of supporting research to broaden the understanding of health and disease.  Paired with each biobank, Mayo fields a community advisory board (CAB), whose members are recruited from the [...]
Community voices guide use of biobank samples in research
Aug 26, 2019

Hospice research aims to understand process of dying, help loved ones with end-of-life care

By Advancing the Science contributor @advancingthescience
While death is inevitable, for patients at Mayo Clinic Health System in Mankato's Hospice Program, the process of dying is becoming more bearable as a result of several research studies aimed at better understanding. Death, ultimately, is inevitable. It happens to everyone. But for patients at Mayo Clinic Health System in Mankato's [...]
Hospice research aims to understand process of dying, help loved ones with end-of-life care
Aug 22, 2019

At Mayo Clinic, one Statistics and Data Management Center oversees hundreds of cancer clinical trials

By Advancing the Science contributor @advancingthescience
By Lydia Hansen, undergraduate public affairs intern The Mayo Clinic Cancer Center’s Statistics and Data Management Center is one of the largest and most highly rated statistics and data management centers working with cancer research in the world. The group has an overall portfolio of 361 cancer-related clinical trials and information on more than 185,000 [...]
At Mayo Clinic, one Statistics and Data Management Center oversees hundreds of cancer clinical trials
Aug 21, 2019

Regenerative Medicine Minnesota: Executing big hairy audacious goals

By Jennifer Schutz @jenniferschutz
The excitement at the 2019 Regenerative Medicine Minnesota meeting was palpable. Health care providers, scientists, educators, students, lawmakers and life sciences entrepreneurs mobilized to celebrate the BHAG—big hairy audacious goals in transforming health care. The BHAG challenge: develop new solutions and innovations that establish Minnesota as a world class leader and destination [...]
Regenerative Medicine Minnesota: Executing big hairy audacious goals
Aug 20, 2019

McArdle's sign, long overlooked, is an indicator of multiple sclerosis

By Advancing the Science contributor @advancingthescience
By Jay Furst McArdle's sign, a distinctive muscle weakness that affects patients with spinal cord disease, was first noted more than 30 years ago. The namesake of the "sign," M.J. McArdle, was a professor of neurology in London, and one of his patients with advanced multiple sclerosis needed to extend his neck and tip his head [...]
McArdle's sign, long overlooked, is an indicator of multiple sclerosis
Aug 19, 2019

Yale and Mayo Clinic awarded FDA grant to study opioid prescribing and use

By Advancing the Science contributor @advancingthescience
— Yale University Office of Public Affairs & Communications Yale University and Mayo Clinic have been awarded a grant for up to $5.3 million over two years by the U.S. Food and Drug Administration (FDA) to study patients’ experiences with pain and use of opioids prescribed for acute pain. This project is part of the Center of Excellence in Regulatory [...]
Yale and Mayo Clinic awarded FDA grant to study opioid prescribing and use
Aug 15, 2019

HLHS consortium gives hope to babies with rare congenital heart defect

By Jennifer Schutz @jenniferschutz
Hypoplastic Left Heart Syndrome (HLHS) is a rare disease that affects approximately 1 of every 4,300 babies every year.  HLHS is a congenital heart defect in which the left side of the heart is underdeveloped. It occurs during fetal growth when the baby's heart is developing. Without immediate intervention after birth, [...]
HLHS consortium gives hope to babies with rare congenital heart defect
Aug 14, 2019

Can BioBanks Help Close Gaps in Health Outcomes?

By Advancing the Science contributor @advancingthescience
By Barbara J. Toman By definition, personalized medicine requires diversity. One-size-fits-all doesn't work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic's Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo's medical research. Sangre [...]
Can BioBanks Help Close Gaps in Health Outcomes?
Aug 13, 2019

Inspired to innovate: Detecting heart disease earlier with the help of artificial intelligence

By Advancing the Science contributor @advancingthescience
By Nicole Sisk Artificial intelligence will play a key role in Mayo Clinic's future and that of health care worldwide. The Department of Cardiovascular Medicine is combining artificial intelligence with standard tests to improve patient care. Each year at Mayo Clinic, 250,000 patients have an electrocardiogram, or ECG. It's a common, [...]
Inspired to innovate: Detecting heart disease earlier with the help of artificial intelligence
Aug 8, 2019

We are the world

By Advancing the Science contributor @advancingthescience
From the earliest days, physicians and scientists have flocked to Mayo Clinic from all over the world to learn: Foreign-born physicians in the early days at Mayo Clinic included Donald Balfour, M.D., of Canada, arriving in 1907; Gordon New, M.D., of Canada, 1910; Frank Smithies, M.D., from England in 1910; [...]
We are the world
Aug 7, 2019

Researcher challenges her team to develop solution for DRC health crisis

By Advancing the Science contributor @advancingthescience
Marina Walther-Antonio, Ph.D., has a full plate. An associate consultant in surgical research in the departments of Surgery and Obstetrics and Gynecology at Mayo Clinic in Rochester, she studies the microbiome role in human health and disease, particularly endometrial and ovarian cancer. She also develops technology in her lab, including [...]
Researcher challenges her team to develop solution for DRC health crisis
Aug 6, 2019

Researching stem cell therapy for hemorrhagic stroke

By Jennifer Schutz @jenniferschutz
Stroke is the leading cause of permanent disability in the U.S., striking nearly 800,000 people each year, according to the Centers for Disease Control and Prevention. In the last decade, there has been preclinical research that led to a small number of early phase clinical trials using mesenchymal stem cells (MSCs) as [...]
Researching stem cell therapy for hemorrhagic stroke
Aug 5, 2019

Blood thinners in combination increase bleeding risk, Mayo study finds

By Adam Harringa @harringaadam
Gastrointestinal bleeding is a common side effect for many blood-thinning medications. But new Mayo Clinic research finds that risk is amplified when patients receive more than one blood thinner – especially if they’re 75 or older. The study, published in Clinical Gastroenterology and Hepatology, found patients receiving an anticoagulant drug and [...]
Blood thinners in combination increase bleeding risk, Mayo study finds
Aug 1, 2019

Research News Roundup--July 2019

By Elizabeth Zimmermann @elizabethzimmermann
The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Racism influences medical students’ decision on practicing in minority or underserved communities, study [...]
Research News Roundup--July 2019
Jul 31, 2019

Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment

By Advancing the Science contributor @advancingthescience
By Sharon Rosen Do you have family members who have been diagnosed with gastrointestinal, breast or ovarian cancer? According to a recent Mayo Clinic study, nearly 5% to 10% of these cancers can be hereditary. That’s why it is important to share your family medical history with your physician, who [...]
Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment
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