Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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Jul 24, 2018

Mayo scientists presenting at Alzheimer's Association conference

By Adam Harringa @harringaadam
About 30 Mayo Clinic scientists are presenting at this week’s Alzheimer’s Association International Conference in Chicago, and another roughly two dozen researchers are contributing authors. They’re among more than 5,600 scientists from 65 countries. The schedule and abstracts are available on the Alzheimer’s Association conference website. All the research has one [...]
Mayo scientists presenting at Alzheimer's Association conference
Jul 19, 2018

A clearer picture: new imaging technologies advance diagnosis, individualized care

By Susan Buckles @susanbuckles
New imaging technologies are advancing diagnosis and individualizing care. Imaging tests – such as a CT scan or MRI – are essential tools that health care providers use to answer complex and challenging questions. Gabriel Krestin, M.D., Ph.D., a radiologist and researcher, is at the forefront of new efforts to [...]
A clearer picture: new imaging technologies advance diagnosis, individualized care
Jul 18, 2018

Popular films spark community dialogue about biomedical ethics

By Caitlin Doran @caityrosey
When was the last time a movie really made you think, changed how you viewed the world or helped you understand an important topic? Bioethics at the Cinema, organized by the Mayo Clinic Biomedical Ethics Program and the Rochester Public Library, wants to do just that. The goal is to use [...]
Popular films spark community dialogue about biomedical ethics
Jul 17, 2018

Researching gene therapy for liver diseases: Joseph Lillegard, M.D., Ph.D.

By Jennifer Schutz @jenniferschutz
Joseph Lillegard, M.D., Ph.D., is a Regenerative Medicine Minnesota research grant recipient. He is researching gene therapy to fight inborn errors of metabolism of the liver, primarily Hereditary Tyrosinemia Type 1 (HT1), a metabolic disorder caused by an enzyme deficiency. HT1 is a genetic disorder that can lead to liver and kidney [...]
Researching gene therapy for liver diseases: Joseph Lillegard, M.D., Ph.D.
Jul 12, 2018

Arresting melanoma's molecular drivers

By Susan Buckles @susanbuckles
This post originally appeared on the Center for Individualized Medicine blog on May 15, 2018. Article by Barbara Toman Melanoma, the skin cancer often associated with sun exposure, is on the rise and has no reliable cure. Mayo Clinic is at the forefront of efforts aimed at increasing early detection and treatment [...]
Arresting melanoma's molecular drivers
Jul 11, 2018

Mayo Clinic-led Study Finds Breast Cancer Survivors Aren't Getting Recommended Number of Mammograms Post-Surgery

By Nicole Brudos Ferrara @nicoleferrara
Breast cancer survivors are not getting the recommended level of post-surgery screening, according to a study published in the May 2018 issue of the Journal of the National Comprehensive Cancer Network (JNCCN).  Contrary to screening recommendations, mammography rates decline over time as women get further out from their breast cancer [...]
Mayo Clinic-led Study Finds Breast Cancer Survivors Aren't Getting Recommended Number of Mammograms Post-Surgery
Jul 10, 2018

Using biological particles from milk to target liver cancer

By Kate Ledger @k8ledger
Among cancers, liver tumors have been particularly hard for doctors to treat. The cancer cells tend to be hardy from the beginning and even undergo changes that make them more resistant to chemotherapies. What’s clear is that an effective treatment needs to reach the cancer cells, and not affect or [...]
Using biological particles from milk to target liver cancer
Jul 9, 2018

Offering underserved groups access to cutting-edge research

By Kris Schanilec @kschanilec
For many patients, clinical trials offer a chance to benefit from promising new treatments that are not available in the doctor’s office. Yet not all people have the same access to these opportunities. Groups such as racial minorities, older individuals, and those with low income are less likely than others [...]
Offering underserved groups access to cutting-edge research
Jul 5, 2018

Research News Roundup-June 2018

By Elizabeth Zimmermann @elizabethzimmermann
Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month's Roundup includes a number of findings related pancreatic cancer and [...]
Research News Roundup-June 2018
Jul 2, 2018

A revolution in pancreatic cancer treatment

By Advancing the Science contributor @advancingthescience
Mark Truty, M.D., has dedicated his career to giving patients with pancreatic cancer more quality time with their loved ones. Much more time. The mission is personal for him. His own father, Kazimierz Truty, a Polish immigrant and mechanic at a meatpacking plant near Chicago, died 20 years ago from pancreatic [...]
A revolution in pancreatic cancer treatment
Jun 29, 2018

New molecular test employs sponge on a string to detect esophageal cancer

By Advancing the Science contributor @advancingthescience
Researchers at Mayo Clinic have developed a new, minimally invasive method to detect and help prevent esophageal cancer in patients at risk for Barrett's esophagus and esophageal cancer. Their study documenting the discovery and validation of novel methylated markers along with results of a pilot study have been published and [...]
New molecular test employs sponge on a string to detect esophageal cancer
Jun 28, 2018

Let's talk about it: Death

By Meghan Knoedler @meghanknoedler
Death. Dying. End of life care. Comfort care. Hospice. In the face of losing someone that we love whether they are young or old; hearing these words uttered and the paralyzing finality and irrevocability of it all compounds the already difficult circumstances. These words conjure up an even more poignant [...]
Let's talk about it: Death
Jun 26, 2018

Register for Transform 2018 today! Discounted rates end June 30

By Advancing the Science contributor @advancingthescience
Accelerating Health Innovation. Focusing on People. It’s by Design. Hosted by Mayo Clinic, Transform has been the preeminent health care conference to proactively confront critical issues, share meaningful insights, and catalyze actionable change for more than a decade. Join us at the Mayo Civic Center, Sept. 26-27, as we explore [...]
Register for Transform 2018 today! Discounted rates end June 30
Jun 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Brudos Ferrara @nicoleferrara
Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, [...]
Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors
Jun 22, 2018

Be the early bird! Register now for the 2018 Individualizing Medicine Conference

By Susan Buckles @susanbuckles
Mayo Clinic Center for Individualized Medicine  is hosting the Individualizing Medicine Conference (#CIMCON18), Sept. 12-13, 2018, in Rochester, Minnesota. #CIMCON18 brings together experts from Mayo Clinic and around the world to discuss how the latest discoveries in precision medicine can be applied to improve patient care. Register today for the conference and [...]
Be the early bird! Register now for the 2018 Individualizing Medicine Conference
Jun 21, 2018

Cell therapy for cartilage defects: Aaron Krych, M.D.

By Jennifer Schutz @jenniferschutz
Aaron Krych, M.D., Mayo Clinic orthopedic surgeon and recipient of a 2018 Regenerative Medicine Research Grant, is researching the initial safety and feasibility of RECLAIM, a single stage cartilage repair technique using the patient’s own cartilage cells and allogeneic mesenchymal stem cells.  The study will assess the patient’s improvement in pain [...]
Cell therapy for cartilage defects: Aaron Krych, M.D.
Jun 19, 2018

'Extraordinary Ability'-Fetal surgery program elevates maternal-fetal medicine

By Advancing the Science contributor @advancingthescience
Imagine being deemed so critical to a health care organization that the state legislature acts immediately to allow you to practice there. That’s how Rodrigo Ruano, M.D., Ph.D., chair of the Division of Maternal Fetal Medicine in the Department of Obstetrics & Gynecology, came to Mayo Clinic in Rochester. Calling [...]
'Extraordinary Ability'-Fetal surgery program elevates maternal-fetal medicine
Jun 18, 2018

On the road to AcademyHealth's Annual Research Meeting

By Elizabeth Zimmermann @elizabethzimmermann
If your calendar is blocked for travel the last week of June, you just might be heading to AcademyHealth’s Annual Research Meeting in Seattle, June 24-26. If so, you should stop by the Mayo Clinic booth #309 for a visit with some of our researchers. Even if you’re not going [...]
On the road to AcademyHealth's Annual Research Meeting
Jun 14, 2018

Bridging the gap: Introducing the health care of tomorrow

By Jennifer Schutz @jenniferschutz
Forward-thinking leadership, unparalleled expertise and a commitment to solving unmet patient needs allow Mayo Clinic to bridge the gap between the delivery of traditional health care today and the rapid advancement of revolutionary care in the near future. Increasing Translational Capabilities Traditionally, it could take years for physician-scientists to develop [...]
Bridging the gap: Introducing the health care of tomorrow
Jun 13, 2018

Following grant renewal, CCaTS abuzz with activity

By Caitlin Doran @caityrosey
In October 2017, the National Institutes of Health (NIH) renewed Mayo Clinic’s Clinical and Translational Science Award from the National Center for Advancing Translational Sciences—an award totaling $48.8 million over five years. This renewal allows Mayo Clinic to continue pursuing its long-term goals in clinical and translational science, while also [...]
Following grant renewal, CCaTS abuzz with activity
Jun 12, 2018

New collaboration to develop and test decisions for AFib patients

By Elizabeth Zimmermann @elizabethzimmermann
The Patient-Centered Outcomes Research Institute (PCORI) and American Heart Association (AHA) announced today that it is establishing  AHA-PCORI Decision-making and Choices to Inform Dialogue and Empower AFib patients (DECIDE) Center. The DECIDE Center will be a collaboration between the University of Utah (where it will be based) and Mayo Clinic. The [...]
New collaboration to develop and test decisions for AFib patients
Jun 12, 2018

Genetic testing to enhance multiple myeloma treatment

By Susan Buckles @susanbuckles
This article originally appeared on the Center for Individualized Medicine blog on March 6, 2018 Article by Barbara Toman Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action [...]
Genetic testing to enhance multiple myeloma treatment
Jun 11, 2018

Bioartificial liver: Potential to avoid transplant

By Nicole Brudos Ferrara @nicoleferrara
Mayo Clinic researchers are planning clinical trials of a bioartificial  liver that might eventually provide an alternative to transplantation for patients with liver failure. Known as the Mayo Spheroid Reservoir Bioartificial Liver (SRBAL), the novel device has been shown to reduce the severity of liver disease and improve survival in [...]
Bioartificial liver: Potential to avoid transplant
Jun 8, 2018

Researchers find link between childhood trauma, recent abuse and more severe menopause symptoms

By Advancing the Science contributor @advancingthescience
By Heather Carlson Kehren Women who have experienced childhood trauma may suffer from more severe hot flashes and night sweats during menopause, according to new Mayo Clinic research presented during the 16th World Congress on Menopause this week. Researchers found an association between women who experienced adverse childhood events (ACEs) [...]
Researchers find link between childhood trauma, recent abuse and more severe menopause symptoms
Jun 7, 2018

Meet Population Health Scholar--Kathy MacLaughlin, M.D.

By Advancing the Science contributor @advancingthescience
The research of Kathy L. MacLaughlin, M.D., focuses on developing and implementing a clinical decision support system to improve clinician compliance with evidence-based guidelines for cervical cancer screening and test result management. Dr. MacLaughlin grew up in Rochester, Minnesota, and graduated from Luther College in Decorah, Iowa. She received her [...]
Meet Population Health Scholar--Kathy MacLaughlin, M.D.
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