Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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Oct 4, 2019

Chemo first for better outcomes in bile duct cancer, says new research

By Elizabeth Zimmermann @elizabethzimmermann
Oncology care teams frequently use chemotherapy along with surgery to treat cholangiocarcinoma, or bile duct cancer. However, until now, little evidence existed regarding if and when receiving chemotherapy was likely to have the best effect. Recently Mayo Clinic researchers found that patients who received chemotherapy before surgery to remove their bile duct [...]
Chemo first for better outcomes in bile duct cancer, says new research
Oct 2, 2019

Research News Roundup--September 2019

By Elizabeth Zimmermann @elizabethzimmermann
The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Medications underused in treating opioid addiction, Mayo Clinic expert says Though research shows that [...]
Research News Roundup--September 2019
Oct 1, 2019

Mayo researcher's work focuses on health care safety and quality

By Advancing the Science contributor @advancingthescience
From a young age, Mohamed Seisa, M.D., had a passion to study biology. His uncle was a pediatrician and his father was a physicist in Egypt, so Dr. Seisa grew up around science. In medical school, he worked in a lab and enjoyed research. But while Dr. Seisa was a [...]
Mayo researcher's work focuses on health care safety and quality
Sep 30, 2019

People with kidney disease should be cautious with supplements, Mayo researchers say

By Adam Harringa @harringaadam
More than one-third of the 15.7 million Americans with moderate or advanced chronic kidney disease use dietary or herbal supplements, reports new research from Mayo Clinic. Many Americans decide to take supplements on their own, not because of a doctor’s recommendation, the researchers found, most often with the goal of [...]
People with kidney disease should be cautious with supplements, Mayo researchers say
Sep 27, 2019

Read the Latest Research News from Mayo Clinic Cancer Center

By Nicole Ferrara @nicoleferrara
Forefront is the complimentary magazine of the Mayo Clinic Cancer Center. Published in email and online newsletter editions quarterly, Forefront highlights Mayo Clinic’s cutting-edge cancer research and the latest Cancer Center news. The September 2019 issue features: Director’s message: Recognition for a job well doneAfter a rigorous review, NCI has renewed Mayo [...]
Read the Latest Research News from Mayo Clinic Cancer Center
Sep 26, 2019

Bioartificial liver: Bridge to liver regeneration

By Jennifer Schutz @jenniferschutz
The liver has the greatest regenerative capacity of any organ in the body. However, when the liver is injured beyond its ability to regenerate itself, and a transplant is not readily available, there are few options for patients. Led by Scott Nyberg, M.D., Ph.D., researchers are refining their own version of a bioartificial liver, known [...]
Bioartificial liver: Bridge to liver regeneration
Sep 24, 2019

Research for infants with HLHS moves forward

By Jennifer Schutz @jenniferschutz
Hypoplastic left heart syndrome (HLHS) is a complex and rare heart defect present at birth in which the left side of a child's heart is severely underdeveloped. At Mayo Clinic, physicians and researchers in the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome are looking for ways to delay or even prevent heart failure for [...]
Research for infants with HLHS moves forward
Sep 23, 2019

Meet Mukesh Pandey, Ph.D. - developing a new drug to detect prostate cancer in its earliest stages

By Advancing the Science contributor @advancingthescience
By Sharon Rosen With a background in organic chemistry, Mukesh Pandey, Ph.D., initially planned to work in the pharmaceutical industry developing medications. But after completing a post-doctoral research fellowship in radiology at Harvard Medical School, he chose to focus his skills on improving imaging technologies to better detect the first signs [...]
Meet Mukesh Pandey, Ph.D. - developing a new drug to detect prostate cancer in its earliest stages
Sep 20, 2019

Good news about the effectiveness of antifibrotics for IPF

By Elizabeth Zimmermann @elizabethzimmermann
In a recent study published in the American Journal of Respiratory and Critical Care, a research team led by Andrew Limper, M.D., a pulmonology and critical care physician at Mayo Clinic, evaluated the effectiveness of pirfenidone and nintedanib for patients with idiopathic pulmonary fibrosis. The researchers reported "the medications had [...]
Good news about the effectiveness of antifibrotics for IPF
Sep 19, 2019

Biostatistician keeps Mayo research ship-shape

By Caitlin Doran @caityrosey
I met Rickey Carter, Ph.D., in his glass-walled office on the Mayo Clinic Florida campus in June. From his desk, he can look out over the Health Sciences Research Department: desks and cubicles in orderly rows, like boats in a marina and humming with activity—activity he helps promote as vice [...]
Biostatistician keeps Mayo research ship-shape
Sep 18, 2019

Genomics and computer science intersect to improve patient care

By Advancing the Science contributor @advancingthescience
By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual [...]
Genomics and computer science intersect to improve patient care
Sep 17, 2019

Mayo Clinic Startup Earns World Economic Forum Award

By Susan Buckles @susanbuckles
With the promise of potential lifesaving treatments like chimeric antigen receptor (CAR) T-Cell therapy comes complex challenges. For instance: how can we be sure the right cells are going to the right patient? How can we communicate problems with manufacturing that would affect a patient’s treatment schedule? To address those concerns, Mayo Clinic startup [...]
Mayo Clinic Startup Earns World Economic Forum Award
Sep 16, 2019

Research breathes new air into donor lungs

By Advancing the Science contributor @advancingthescience
By Sara Nick Four hundred: That’s the number of U.S. patients who die each year awaiting a lung transplant, or are removed from the wait list when they become too ill. Now, cutting-edge research underway on Mayo Clinic’s Florida campus aims to save as many of those lives as possible. “We’re [...]
Research breathes new air into donor lungs
Sep 13, 2019

REAL WORLD EVIDENCE in health care improvement

By Elizabeth Zimmermann @elizabethzimmermann
In late 2012 Optum and Mayo Clinic came together to form OptumLabs, an open, collaborative research and innovation center, dedicated to improving patient care and patient value through data-driven health care research, leading-edge data science and strong partner collaboration.  Since that time, approximately 150 collaborative projects have led to peer-reviewed publication, [...]
REAL WORLD EVIDENCE in health care improvement
Sep 12, 2019

Behind the scenes--Mayo Clinic Research

By Elizabeth Zimmermann @elizabethzimmermann
Everything health care has to offer for patients is the result of research and education related to that research. At Mayo Clinic, research drives everything we do, resulting in evidence-based treatments and continuous improvements in the way patients, caregivers and others experience health care. At Mayo Clinic we share information about [...]
Behind the scenes--Mayo Clinic Research
Sep 11, 2019

Targeting therapy to each patient's unique cancer

By Advancing the Science contributor @advancingthescience
Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center, will speak on Decision [...]
Targeting therapy to each patient's unique cancer
Sep 10, 2019

Mayo fellow already an internationally recognized expert on celiac disease

By Advancing the Science contributor @advancingthescience
Alberto Rubio Tapia, M.D., was a fellowship-trained gastroenterologist in Mexico. He came to Mayo Clinic in 2006 to gain research experience. “My institution in Mexico City, National Institute of Medical Sciences and Nutrition (Salvador Zubiran), has a long tradition in clinical and research training collaboration with Mayo Clinic, so I [...]
Mayo fellow already an internationally recognized expert on celiac disease
Sep 9, 2019

Mayo Clinic Cancer Center Renews National Cancer Institute Research Funding

By Nicole Ferrara @nicoleferrara
Mayo Clinic Cancer Center has once again successfully renewed its National Cancer Institute (NCI) Cancer Center Support Grant. The grant award provides roughly $28.7 million in funding over five years through 2024, which will mark Mayo Clinic’s 49th year of NCI funding. Mayo Clinic Cancer Center’s NCI designation as a comprehensive [...]
Mayo Clinic Cancer Center Renews National Cancer Institute Research Funding
Sep 5, 2019

If it isn't broken, why fix it? Advancements in multiple myeloma diagnosis.

By Advancing the Science contributor @advancingthescience
The standard laboratory test to diagnose multiple myeloma dates back to the Eisenhower administration. Research at Mayo Clinic spearheaded by David Murray, M.D., Ph.D., and fueled by his experience as an industrial chemist has led to a new assay to screen and diagnose the disease. Lacking in speed and specificity [...]
If it isn't broken, why fix it? Advancements in multiple myeloma  diagnosis.
Sep 4, 2019

Mayo experts provide insights into how genes affect medication response

By Advancing the Science contributor @advancingthescience
By Sharon Rosen Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that [...]
Mayo experts provide insights into how genes affect medication response
Sep 3, 2019

Research News Roundup--August 2019

By Elizabeth Zimmermann @elizabethzimmermann
Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. Read on for recent findings of Mayo Clinic Research: Genetically manipulating protein level in colon [...]
Research News Roundup--August 2019
Aug 28, 2019

Grant supplement opens doors for future cancer researchers in Native American communities

By Advancing the Science contributor @advancingthescience
By Lydia Hansen, Public Affairs undergraduate intern In the summer of 2014, Corinna Sabaque moved over 1,000 miles from her home in the Four Corners area in New Mexico to Rochester, Minn. to complete a 10-week internship in breast cancer research at Mayo Clinic. “Coming to Minnesota was hard,” Sabaque says. “I didn’t know anybody. [...]
Grant supplement opens doors for future cancer researchers in Native American communities
Aug 27, 2019

Community voices guide use of biobank samples in research

By Caitlin Doran @caityrosey
Mayo Clinic supports biobanks—large collections of patient biological samples—near each of its three campuses in Arizona, Florida, and Minnesota, with the goal of supporting research to broaden the understanding of health and disease.  Paired with each biobank, Mayo fields a community advisory board (CAB), whose members are recruited from the [...]
Community voices guide use of biobank samples in research
Aug 26, 2019

Hospice research aims to understand process of dying, help loved ones with end-of-life care

By Advancing the Science contributor @advancingthescience
While death is inevitable, for patients at Mayo Clinic Health System in Mankato's Hospice Program, the process of dying is becoming more bearable as a result of several research studies aimed at better understanding. Death, ultimately, is inevitable. It happens to everyone. But for patients at Mayo Clinic Health System in Mankato's [...]
Hospice research aims to understand process of dying, help loved ones with end-of-life care
Aug 22, 2019

At Mayo Clinic, one Statistics and Data Management Center oversees hundreds of cancer clinical trials

By Advancing the Science contributor @advancingthescience
By Lydia Hansen, undergraduate public affairs intern The Mayo Clinic Cancer Center’s Statistics and Data Management Center is one of the largest and most highly rated statistics and data management centers working with cancer research in the world. The group has an overall portfolio of 361 cancer-related clinical trials and information on more than 185,000 [...]
At Mayo Clinic, one Statistics and Data Management Center oversees hundreds of cancer clinical trials
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