Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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Aug 16, 2018

Investigating gene therapy strategies for obesity: Ping Chen, Ph.D.

By Jennifer Schutz @jenniferschutz
The major challenge in treating obesity is not just losing weight, but preventing weight from coming back. With a research grant form Regenerative Medicine Minnesota, Ping (Vicky) Chen, Ph.D., Mayo Clinic research associate,  is studying a new treatment strategy using gene transfer therapy to safely target brain mechanisms that control [...]
Investigating gene therapy strategies for obesity: Ping Chen, Ph.D.
Aug 14, 2018

Research suggests genetics are key in treating night sweats

By Advancing the Science contributor @advancingthescience
This post originally was published on the Center for Individualized Medicine blog on June 25, 2018 Article by Heather Carlson Women going through menopause know all too well the discomfort associated with night sweats. Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen [...]
Research suggests genetics are key in treating night sweats
Aug 9, 2018

Using CSI-type technology to unravel the source of bacteria

By Susan Buckles @susanbuckles
This article originally appeared on the Center for Individualized Medicine blog on May 28, 2018. Mayo Clinic laboratory workers have a new tool to perform high tech genetic sleuthing for the source of stubborn, sometimes life-threatening bacteria. Bacterial whole genome sequencing can trace individual isolates of bacteria such as Staphylococcus [...]
Using CSI-type technology to unravel the source of bacteria
Aug 8, 2018

New pathway in prostate cancer cells suggests possible therapy

By Sara Tiner @saratiner
Expanding on previous findings, a group of Mayo researchers continue using discovery research in cells to find options for treating cancers. In their most recent paper, published in Molecular Cell, the team's research suggest that a drug used for breast cancer may be helpful in some types of prostate cancers. [...]
New pathway in prostate cancer cells suggests possible therapy
Aug 7, 2018

Senescent cells and aging: Following up on the unexpected pays off

By Advancing the Science contributor @advancingthescience
Starting at age 8, Jan van Deursen, Ph.D., helped his carpenter father on the weekends when he built custom staircases, windows and doors for people in their village in the Netherlands. “My father had a fast pace, and I had to keep up with him,” says Dr. van Deursen. “I didn’t [...]
Senescent cells and aging:  Following up on	the unexpected pays off
Aug 6, 2018

Regenerative medicine in novel fetal therapy program

By Jennifer Schutz @jenniferschutz
A life-saving procedure improves fetal lung health and reduces post-natal complications Specialists at Mayo Clinic are pioneering a life-saving procedure as part of a clinical trial for babies with congenital diaphragmatic hernia (CDH). When a baby’s lungs are not adequately developed at birth, severe complications and even death can result. Waiting [...]
Regenerative medicine in novel fetal therapy program
Aug 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann @elizabethzimmermann
The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In [...]
Research News Roundup-July 2018
Aug 1, 2018

Mentorship program makes research aspirations a reality

By Caitlin Doran @caityrosey
Mrinal Patnaik, M.B.B.S., is a physician in the Department of Hematology at Mayo Clinic with a keen interest in the clinical management of blood cancers. In recent years, however, Dr. Patnaik realized he wanted to develop a deeper understanding of the disease biology of these cancers and the ways that [...]
Mentorship program makes research aspirations a reality
Jul 31, 2018

Banking on improved health

By Advancing the Science contributor @advancingthescience
This article originally appeared on the Center for Individualized Medicine blog on June 4, 2018. Article by Barbara Toman Just as money in the bank boosts your financial well-being, biobanks have the power to impact your health. Think of biobank samples as assets that researchers can draw upon to improve [...]
Banking on improved health
Jul 30, 2018

What's new on the web?

By Elizabeth Zimmermann @elizabethzimmermann
At Mayo Clinic, research is integral to everything we do. We would be unable to offer the highest possible levels of care and continually improve the practice of medicine without research, and the education programs and processes that underpin our care. Our research web is actually just a section of Mayo Clinic's internet presence, [...]
What's new on the web?
Jul 26, 2018

Submit abstracts for 2018 Symposium on Regenerative Medicine and Surgery

By Jennifer Schutz @jenniferschutz
Abstracts are now being accepted for the Mayo Clinic Symposium on Regenerative Medicine and Surgery. The symposium will be held Nov. 29-Dec. 1, 2018 at the Westin Kierland Resort & Spa in Scottsdale, Arizona. Interested physicians, researchers, medical students, post-doctoral and pre-doctoral students, as well as allied health staff, are invited [...]
Submit abstracts for 2018 Symposium on Regenerative Medicine and Surgery
Jul 25, 2018

Advances in lung cancer immunotherapy and management of immune-mediated adverse events

By Advancing the Science contributor @advancingthescience
Over the last few years, immunotherapy using immune checkpoint inhibitors targeting programmed cell death receptor 1 (PD-1) or programmed cell death receptor ligand 1 (PD-L1) has revolutionized the therapeutic approach to advanced-stage non-small cell lung cancer and numerous other malignancies. Monotherapy, using the anti-PD-1 antibody pembrolizumab, is now Food and [...]
Advances in lung cancer immunotherapy and management of immune-mediated adverse events
Jul 24, 2018

Mayo scientists presenting at Alzheimer's Association conference

By Adam Harringa @harringaadam
About 30 Mayo Clinic scientists are presenting at this week’s Alzheimer’s Association International Conference in Chicago, and another roughly two dozen researchers are contributing authors. They’re among more than 5,600 scientists from 65 countries. The schedule and abstracts are available on the Alzheimer’s Association conference website. All the research has one [...]
Mayo scientists presenting at Alzheimer's Association conference
Jul 19, 2018

A clearer picture: new imaging technologies advance diagnosis, individualized care

By Susan Buckles @susanbuckles
New imaging technologies are advancing diagnosis and individualizing care. Imaging tests – such as a CT scan or MRI – are essential tools that health care providers use to answer complex and challenging questions. Gabriel Krestin, M.D., Ph.D., a radiologist and researcher, is at the forefront of new efforts to [...]
A clearer picture: new imaging technologies advance diagnosis, individualized care
Jul 18, 2018

Popular films spark community dialogue about biomedical ethics

By Caitlin Doran @caityrosey
When was the last time a movie really made you think, changed how you viewed the world or helped you understand an important topic? Bioethics at the Cinema, organized by the Mayo Clinic Biomedical Ethics Program and the Rochester Public Library, wants to do just that. The goal is to use [...]
Popular films spark community dialogue about biomedical ethics
Jul 17, 2018

Researching gene therapy for liver diseases: Joseph Lillegard, M.D., Ph.D.

By Jennifer Schutz @jenniferschutz
Joseph Lillegard, M.D., Ph.D., is a Regenerative Medicine Minnesota research grant recipient. He is researching gene therapy to fight inborn errors of metabolism of the liver, primarily Hereditary Tyrosinemia Type 1 (HT1), a metabolic disorder caused by an enzyme deficiency. HT1 is a genetic disorder that can lead to liver and kidney [...]
Researching gene therapy for liver diseases: Joseph Lillegard, M.D., Ph.D.
Jul 12, 2018

Arresting melanoma's molecular drivers

By Susan Buckles @susanbuckles
This post originally appeared on the Center for Individualized Medicine blog on May 15, 2018. Article by Barbara Toman Melanoma, the skin cancer often associated with sun exposure, is on the rise and has no reliable cure. Mayo Clinic is at the forefront of efforts aimed at increasing early detection and treatment [...]
Arresting melanoma's molecular drivers
Jul 11, 2018

Mayo Clinic-led Study Finds Breast Cancer Survivors Aren't Getting Recommended Number of Mammograms Post-Surgery

By Nicole Brudos Ferrara @nicoleferrara
Breast cancer survivors are not getting the recommended level of post-surgery screening, according to a study published in the May 2018 issue of the Journal of the National Comprehensive Cancer Network (JNCCN).  Contrary to screening recommendations, mammography rates decline over time as women get further out from their breast cancer [...]
Mayo Clinic-led Study Finds Breast Cancer Survivors Aren't Getting Recommended Number of Mammograms Post-Surgery
Jul 10, 2018

Using biological particles from milk to target liver cancer

By Kate Ledger @k8ledger
Among cancers, liver tumors have been particularly hard for doctors to treat. The cancer cells tend to be hardy from the beginning and even undergo changes that make them more resistant to chemotherapies. What’s clear is that an effective treatment needs to reach the cancer cells, and not affect or [...]
Using biological particles from milk to target liver cancer
Jul 9, 2018

Offering underserved groups access to cutting-edge research

By Kris Schanilec @kschanilec
For many patients, clinical trials offer a chance to benefit from promising new treatments that are not available in the doctor’s office. Yet not all people have the same access to these opportunities. Groups such as racial minorities, older individuals, and those with low income are less likely than others [...]
Offering underserved groups access to cutting-edge research
Jul 5, 2018

Research News Roundup-June 2018

By Elizabeth Zimmermann @elizabethzimmermann
Each month, we publish Mayo Clinic's Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month's Roundup includes a number of findings related pancreatic cancer and [...]
Research News Roundup-June 2018
Jul 2, 2018

A revolution in pancreatic cancer treatment

By Advancing the Science contributor @advancingthescience
Mark Truty, M.D., has dedicated his career to giving patients with pancreatic cancer more quality time with their loved ones. Much more time. The mission is personal for him. His own father, Kazimierz Truty, a Polish immigrant and mechanic at a meatpacking plant near Chicago, died 20 years ago from pancreatic [...]
A revolution in pancreatic cancer treatment
Jun 29, 2018

New molecular test employs sponge on a string to detect esophageal cancer

By Advancing the Science contributor @advancingthescience
Researchers at Mayo Clinic have developed a new, minimally invasive method to detect and help prevent esophageal cancer in patients at risk for Barrett's esophagus and esophageal cancer. Their study documenting the discovery and validation of novel methylated markers along with results of a pilot study have been published and [...]
New molecular test employs sponge on a string to detect esophageal cancer
Jun 28, 2018

Let's talk about it: Death

By Meghan Knoedler @meghanknoedler
Death. Dying. End of life care. Comfort care. Hospice. In the face of losing someone that we love whether they are young or old; hearing these words uttered and the paralyzing finality and irrevocability of it all compounds the already difficult circumstances. These words conjure up an even more poignant [...]
Let's talk about it: Death
Jun 26, 2018

Register for Transform 2018 today! Discounted rates end June 30

By Advancing the Science contributor @advancingthescience
Accelerating Health Innovation. Focusing on People. It’s by Design. Hosted by Mayo Clinic, Transform has been the preeminent health care conference to proactively confront critical issues, share meaningful insights, and catalyze actionable change for more than a decade. Join us at the Mayo Civic Center, Sept. 26-27, as we explore [...]
Register for Transform 2018 today! Discounted rates end June 30
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