Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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Jun 26, 2018

Register for Transform 2018 today! Discounted rates end June 30

By Advancing the Science contributor @advancingthescience
Accelerating Health Innovation. Focusing on People. It’s by Design. Hosted by Mayo Clinic, Transform has been the preeminent health care conference to proactively confront critical issues, share meaningful insights, and catalyze actionable change for more than a decade. Join us at the Mayo Civic Center, Sept. 26-27, as we explore [...]
Register for Transform 2018 today! Discounted rates end June 30
Jun 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Brudos Ferrara @nicoleferrara
Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, [...]
Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors
Jun 22, 2018

Be the early bird! Register now for the 2018 Individualizing Medicine Conference

By Susan Buckles @susanbuckles
Mayo Clinic Center for Individualized Medicine  is hosting the Individualizing Medicine Conference (#CIMCON18), Sept. 12-13, 2018, in Rochester, Minnesota. #CIMCON18 brings together experts from Mayo Clinic and around the world to discuss how the latest discoveries in precision medicine can be applied to improve patient care. Register today for the conference and [...]
Be the early bird! Register now for the 2018 Individualizing Medicine Conference
Jun 21, 2018

Cell therapy for cartilage defects: Aaron Krych, M.D.

By Jennifer Schutz @jenniferschutz
Aaron Krych, M.D., Mayo Clinic orthopedic surgeon and recipient of a 2018 Regenerative Medicine Research Grant, is researching the initial safety and feasibility of RECLAIM, a single stage cartilage repair technique using the patient’s own cartilage cells and allogeneic mesenchymal stem cells.  The study will assess the patient’s improvement in pain [...]
Cell therapy for cartilage defects: Aaron Krych, M.D.
Jun 19, 2018

'Extraordinary Ability'-Fetal surgery program elevates maternal-fetal medicine

By Advancing the Science contributor @advancingthescience
Imagine being deemed so critical to a health care organization that the state legislature acts immediately to allow you to practice there. That’s how Rodrigo Ruano, M.D., Ph.D., chair of the Division of Maternal Fetal Medicine in the Department of Obstetrics & Gynecology, came to Mayo Clinic in Rochester. Calling [...]
'Extraordinary Ability'-Fetal surgery program elevates maternal-fetal medicine
Jun 18, 2018

On the road to AcademyHealth's Annual Research Meeting

By Elizabeth Zimmermann @elizabethzimmermann
If your calendar is blocked for travel the last week of June, you just might be heading to AcademyHealth’s Annual Research Meeting in Seattle, June 24-26. If so, you should stop by the Mayo Clinic booth #309 for a visit with some of our researchers. Even if you’re not going [...]
On the road to AcademyHealth's Annual Research Meeting
Jun 14, 2018

Bridging the gap: Introducing the health care of tomorrow

By Jennifer Schutz @jenniferschutz
Forward-thinking leadership, unparalleled expertise and a commitment to solving unmet patient needs allow Mayo Clinic to bridge the gap between the delivery of traditional health care today and the rapid advancement of revolutionary care in the near future. Increasing Translational Capabilities Traditionally, it could take years for physician-scientists to develop [...]
Bridging the gap: Introducing the health care of tomorrow
Jun 13, 2018

Following grant renewal, CCaTS abuzz with activity

By Caitlin Doran @caityrosey
In October 2017, the National Institutes of Health (NIH) renewed Mayo Clinic’s Clinical and Translational Science Award from the National Center for Advancing Translational Sciences—an award totaling $48.8 million over five years. This renewal allows Mayo Clinic to continue pursuing its long-term goals in clinical and translational science, while also [...]
Following grant renewal, CCaTS abuzz with activity
Jun 12, 2018

New collaboration to develop and test decisions for AFib patients

By Elizabeth Zimmermann @elizabethzimmermann
The Patient-Centered Outcomes Research Institute (PCORI) and American Heart Association (AHA) announced today that it is establishing  AHA-PCORI Decision-making and Choices to Inform Dialogue and Empower AFib patients (DECIDE) Center. The DECIDE Center will be a collaboration between the University of Utah (where it will be based) and Mayo Clinic. The [...]
New collaboration to develop and test decisions for AFib patients
Jun 12, 2018

Genetic testing to enhance multiple myeloma treatment

By Susan Buckles @susanbuckles
This article originally appeared on the Center for Individualized Medicine blog on March 6, 2018 Article by Barbara Toman Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action [...]
Genetic testing to enhance multiple myeloma treatment
Jun 11, 2018

Bioartificial liver: Potential to avoid transplant

By Nicole Brudos Ferrara @nicoleferrara
Mayo Clinic researchers are planning clinical trials of a bioartificial  liver that might eventually provide an alternative to transplantation for patients with liver failure. Known as the Mayo Spheroid Reservoir Bioartificial Liver (SRBAL), the novel device has been shown to reduce the severity of liver disease and improve survival in [...]
Bioartificial liver: Potential to avoid transplant
Jun 8, 2018

Researchers find link between childhood trauma, recent abuse and more severe menopause symptoms

By Advancing the Science contributor @advancingthescience
By Heather Carlson Kehren Women who have experienced childhood trauma may suffer from more severe hot flashes and night sweats during menopause, according to new Mayo Clinic research presented during the 16th World Congress on Menopause this week. Researchers found an association between women who experienced adverse childhood events (ACEs) [...]
Researchers find link between childhood trauma, recent abuse and more severe menopause symptoms
Jun 7, 2018

Meet Population Health Scholar--Kathy MacLaughlin, M.D.

By Advancing the Science contributor @advancingthescience
The research of Kathy L. MacLaughlin, M.D., focuses on developing and implementing a clinical decision support system to improve clinician compliance with evidence-based guidelines for cervical cancer screening and test result management. Dr. MacLaughlin grew up in Rochester, Minnesota, and graduated from Luther College in Decorah, Iowa. She received her [...]
Meet Population Health Scholar--Kathy MacLaughlin, M.D.
Jun 6, 2018

Researchers seeking to identify families at risk for cancer

By Susan Buckles @susanbuckles
This article originally appeared on the Center for Individualized Medicine blog on March 13, 2018  Physician-researchers within Mayo Clinic’s Hereditary Cancer Clinic are seeking to usher in a new era of identification and prevention for those with inherited risk of cancer. With support from the Center for Individualized Medicine, they [...]
Researchers seeking to identify families at risk for cancer
Jun 5, 2018

Research News Roundup--May 2018

By Elizabeth Zimmermann @elizabethzimmermann
The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. News flash about hot flashes: They can last longer than you think Mayo Clinic study finds women [...]
Research News Roundup--May 2018
May 31, 2018

Researching Regenerative Strategies to Optimize Neurological Function

By Jennifer Schutz @jenniferschutz
Mayo Clinic neurosurgeon and recipient of a 2018 Regenerative Medicine Minnesota research grant, Terry Burns, M.D., Ph.D., is developing regenerative strategies to optimize neurological function and quality of life for patients with brain tumors, neurological injuries, and neurodegenerative diseases. The decline of memory and thinking processes seen in aging, neurodegenerative [...]
Researching Regenerative Strategies to Optimize Neurological Function
May 30, 2018

Florida symposium on Alzheimer's disease features Mayo Clinic researchers and state-based research findings

By Lynda de Widt @ldewidt
June is national Alzheimer’s and Brain Health Awareness Month—and in Florida—research investigators from around the state will gather in Orlando to highlight basic science advances for this devastating disease. The Florida Health Alzheimer’s Disease Awareness & Research Symposium, June 7-8, features presentations by several Mayo Clinic researchers from Florida and is [...]
Florida symposium on Alzheimer's disease features Mayo Clinic researchers and state-based research findings
May 29, 2018

Clinical trial investigates stem cell therapies for spinal cord injuries

By Jennifer Schutz @jenniferschutz
Mayo Clinic neurosurgeon, Mohamad Bydon, M.D., is a research grant recipient from Regenerative Medicine Minnesota. His clinical trial investigates whether adipose-derived (fat tissue-derived) mesenchymal stem cells can be safely administered into the cerebrospinal fluid of patients with traumatic spinal cord injury and what the effects this may have on functional improvement, [...]
Clinical trial investigates stem cell therapies for spinal cord injuries
May 28, 2018

Registration ends June 7 for workshop to teach application of video research method in medical practice

By Adam Harringa @harringaadam
Register now for Video Reflexive Ethnography course – June 28-30 Video reflexive ethnography (VRE) is an established, collaborative methodology that uses video to capture the complexities of health care and to identify – with participants – ways to improve the delivery of health care from the “bottom up.” Clinicians and [...]
May 24, 2018

Mayo's RIGHT 10K - moving pharmacogenomics into everyday clinical practice

By Susan Buckles @susanbuckles
This article originally appeared on the Center for Individualized Medicine blog on March 20, 2018. By Sharon Rosen After nearly half a century of research, Mayo Clinic is a leader in moving pharmacogenomics into clinical practice. This year pharmacogenomics test results for 10,000 Mayo Clinic patients, all participants in the RIGHT [...]
Mayo's RIGHT 10K - moving pharmacogenomics into everyday clinical practice
May 22, 2018

3-Minute Champion

By Matthew Brenden @matthewjb
The winning institution in the 2018 Midwestern Association of Graduate Schools (MAGS) Three-Minute Thesis (3-MT) competition on April 6 was Mayo Clinic Graduate School of Biomedical Sciences, represented by Gabriel Martínez-Gálvez, a fourth-year Ph.D. candidate at Mayo Clinic Graduate School of Biomedical Sciences. 3-MT presentations describe Ph.D. thesis work with [...]
3-Minute Champion
May 17, 2018

Researching cartilage regeneration for osteoarthritis: Jennifer Westendorf, Ph.D.

By Jennifer Schutz @jenniferschutz
Mayo Clinic investigator, Jennifer Westendorf, Ph.D., is a recipient of a 2018 Regenerative Medicine Minnesota research grant. Her project will help determine how proteins, called Girk2 and Girk3, contribute to cartilage formation and repair in the setting of osteoarthritis. Researchers believe that osteoarthritis may be prevented if these proteins are absent [...]
Researching cartilage regeneration for osteoarthritis: Jennifer Westendorf, Ph.D.
May 16, 2018

Using Big Data to Reduce Waste and Improve Care For Colorectal Cancer Patients

By Meghan Knoedler @meghanknoedler
Colorectal cancer is the third cause of cancer deaths in the United States for both men and women. Not only is colon cancer a common cancer, a significant proportion of these patients undergo treatment. The treatment is complicated and may involve inpatient and outpatient settings as well as multiple specialists. [...]
Using Big Data to Reduce Waste and Improve Care For Colorectal Cancer Patients
May 10, 2018

Imagine the future

By Jennifer Schutz @jenniferschutz
Imagine the Future Imagine a world without organ failure, oxygen tanks and osteoarthritis — a place where insulin is a treatment of the past and “incurable” is no longer in the lexicon of health care professionals. Imagine if you could become the cure to your condition, able to empower the previously untapped [...]
Imagine the future
May 8, 2018

Doctor, are you feeling okay?

By Elizabeth Zimmermann @elizabethzimmermann
For physicians, the practice of medicine comes with a cost beyond medical school bills. In many cases, our doctors pay in health and wellness. And Americans pays, too. Mayo Clinic researchers and collaborators have estimated that the annual cost of physicians leaving the medical profession or making an error due [...]
Doctor, are you feeling okay?
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