Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Findings

If the article talks about a research paper, use this category

October 4, 2022

AI enables early identification, intervention in debilitating lung disease

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

In a new study published in Nature Medicine, Mayo Clinic and several research collaborators from across the U.S., describe a successful new artificial intelligence, or AI, -enabled tool to identify idiopathic pulmonary fibrosis, also called IPF, before patients have recognizable symptoms. This tool could alert a patient’s primary care team of a probable IPF diagnosis […]

View full entry

Tags: artificial intelligence, big data, Center for the Science of Health Care Delivery, clinical informatics, collaboration, idiopathic pulmonary fibrosis, patient reported outcomes, pulmonary and critical care medicine, shared decision making, team science


September 29, 2022

Mayo Clinic study indicates rural US counties have higher diabetes-related deaths

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study, Mayo Clinic researchers identified substantial health disparities in rural versus urban areas in diabetes-related deaths, with other disparities based on gender. Using nationwide data from the Centers for Disease Control and Prevention, the researchers examined rates and trends from 1999 to 2018, in diabetes-related deaths among adults based on county urbanization, […]

View full entry

Tags: Adrian Vella, diabetes, endocrinology, epidemiology, health disparities, heart health, multiple chronic conditions, rural health care, Sagar Dugani


September 22, 2022

A preclinical step toward treating chronic dry mouth

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]

View full entry

Tags: basic science, Center for Regenerative Medicine, discovery research, dry mouth, head and neck cancer, Jeffrey Janus, medical research, Nagarajan Kannan, otolaryngology, quality of life, radiation therapy, salivary glands


September 21, 2022

Maintaining quality care for patients with ALS — Lessons from the pandemic

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Susan Barber Lindquist The efficiency and effectiveness of telemedicine exploded during the COVID-19 pandemic. For patients with Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis or ALS, telemedicine always has been an important piece of their medical care. A recent study in Neurology by Mayo Clinic researchers offers one more proof point. Tests […]

View full entry

Tags: ALS, amyotrophic lateral sclerosis, clinical trials, COVID-19, Lou Gehrig's disease, Nathan Staff, neurology, remote patient monitoring, telehealth, telemedicine


July 27, 2022

Big data dive confirms early intervention nets better outcomes for people with new onset AFib

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Recent research led by Mayo Clinic showed the findings of the international clinical trial — Early Treatment of Atrial Fibrillation for Stroke Prevention Trial, or EAST‐AFNET 4 — are generalizable to routine clinical practice. The new findings are published online in the Journal of the American Heart Association. The original clinical trial included 2,789 patients […]

View full entry

Tags: AFib, atrial fibrillation, big data, cardiovascular medicine, Center for the Science of Health Care Delivery, clinical trials, collaboration, Douglas Packer, EKG, electrocardiogram, health sciences research, Kern Health Care Delivery Scholars


July 19, 2022

Molecular mapping of the heart to predict disease susceptibility

By Susan Buckles Susan Buckles (@susanbuckles)

Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]

View full entry

Tags: Andre Terzic, cardiac regeneration, Center for Regenerative Medicine, heart disease, Kent Arrell, Marriott Family Comprehensive Cardiac Regenerative Program, multiomics, Satsuki Yamada


July 7, 2022

Researchers validate threshold for determining effectiveness of antidepressant treatment

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Lynda De Widt Over one-third of people diagnosed with major depressive disorder don’t respond sufficiently to specific antidepressant treatments. As a result, often patients need to try different options until they find one that is effective. There are validated definitions of good treatment effects. But the definition of ineffective treatment has been less clear, […]

View full entry

Tags: depression, medication management, patient reported outcomes, pharmacology, psychiatry, William Bobo


June 30, 2022

Lupus rates increasing, communities of color especially vulnerable

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

New research led by Mayo Clinic shows that more people are being diagnosed with lupus than in the past, while risks of severity and death remain the same. The study is published in BMJ Annals of the Rheumatologic Diseases. Lupus is a chronic autoimmune disorder that causes inflammation and pain throughout the body. Most common in […]

View full entry

Tags: Alain Sanchez Rodriguez, Ali Duarte Garcia, autoimmune disorder, Center for the Science of Health Care Delivery, Centers for Disease Control and Prevention, Cindy Crowson, epidemiology, health disparities, Jesse Dabit, Kern Health Care Delivery Scholars, lupus, rheumatology


June 21, 2022

What’s behind patient requests for stem cells?

By Susan Buckles Susan Buckles (@susanbuckles)

In one of the first studies of its kind, Mayo Clinic analyzed a large group of patients to understand their motivations for seeking stem cell therapies and whether expectations are grounded in science. The findings could help health care professionals cut through misleading claims and better counsel patients. This research by Jennifer Arthurs; Zubin Master, […]

View full entry

Tags: biomedical ethics, Center for Regenerative Medicine, clinical research, Jennifer Arthurs, orthopedics, Shane Shapiro, stem cells, Zubin Master


June 15, 2022

Research News Roundup — May 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In May, researchers from Mayo Clinic reported gains in understanding of the benefit of AI-enabled ECGs, including from wearable devices. They made strides towards more effective treatment of non-Hodgkin lymphoma and nonmetastatic gastroesophageal cancer. And in news many people can use, investigators report on the results of a survey linked to the Mayo Clinic Diet. […]

View full entry

Tags: AFib, artificial intelligence, atrial fibrillation, CAR-T cell therapy, Center for the Science of Health Care Delivery, clinical trials, cognitive impairment, EKG, electrocardiogram, esophageal cancer, gastric cancer, gastroesophageal cancer


Contact Us · Privacy Policy