Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Innovations

Exciting new things. Not a catch-all for all research.

April 23, 2019

Testing the bugs within to maintain health, detect and treat disease

By Susan Buckles susanbuckles

Article by Sharon Rosen The use of microbiome testing – which analyzes the trillions of bacteria in and on the body – is on the move. It’s going from the research lab into the clinic to help guide patient care. DNA testing technologies have revolutionized researchers’ ability to identify individual bacterial strains driving disease. Now […]

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Tags: Center for Individualized Medicine, colorectal cancer, digestive diseases, DNA testing, gastroenterology, gut health, microbiome, Purna Kashyap


April 15, 2019

Culturally relevant health app shows positive impact

By Advancing the Science contributor advancingthescience

By Jay Furst Mobile apps are popular sources of fast and easily digested consumer health information. But can they actually help in measurable ways to make you more healthy? According to a pilot study by Mayo Clinic researchers, they can if the content is presented in a culturally relevant, targeted and engaging way — and […]

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Tags: artificial intelligence, cardiology, Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, diversity, health disparities, LaPrincess Brewer, Office of Health Disparities Research, women's health


April 10, 2019

Genetic testing reveals risk, steps to prevent aortic dissection

By Susan Buckles susanbuckles

Article by Sharon Rosen Stephanie Van Doren never realized that taking 30 mile bike rides in the Florida heat was putting her life at risk. But, care for digestive problems also uncovered that she was at risk for an aortic dissection, a potentially fatal condition that could occur with intense exercise. Her care team at […]

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Tags: Center for Individualized Medicine, genetic counseling, genetic testing, hereditary diseases, Timothy Woodward


March 21, 2019

Colon cancer: a new era in cancer screening and detection

By Susan Buckles susanbuckles

March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]

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Tags: cancer genomics, Center for Individualized Medicine, colon cancer, hereditary cancer, Lynch syndrome, Niloy "Jewel" Samadder, precision medicine


March 13, 2019

Business innovation with an eye on improving vision

By Susan Buckles susanbuckles

If eyes are the window to the world, Timothy W. Olsen, M.D. is building high performance window frames. With a passion for restoring vision, the ophthalmologist set sights on developing and bringing to market a first-of-its-kind device for treating age-related macular degeneration. The synergies around the Destination Medical Center economic initiative and Mayo Clinic’s research […]

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Tags: age-related macular degeneration, Destination Medical Center, life sciences discovery, medical innovation, ophthalmology, Timothy W. Olsen


March 7, 2019

What do Yellowstone rocks teach us about kidney stones

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog. Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized […]

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Tags: Center for Individualized Medicine, kidney stones, medical research, microbiome, Nicholas Chia


February 11, 2019

Zooming in on Colon Polyps

By Kate Ledger k8ledger

Gastroenterologists agree that removing a colorectal polyp is an important step in preventing colon cancer, but one challenge has been excising polyps that are large, particularly those that are flat and more than an inch in diameter. A recently introduced minimally-invasive approach, called endoscopic mucosal resection, or EMR, facilitates the removal of large polyps without […]

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Tags: cancer prevention, colon cancer, colon polyp, gastroenterology, Mayo Clinic Cancer Center, Michael Wallace, minimally invasive surgery


January 22, 2019

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Advancing the Science contributor advancingthescience

By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can […]

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Tags: cancer, Center for Individualized Medicine, individualized medicine, Mayo Clinic Cancer Center, personalized medicine, pharmacogenomics, Robert Diasio


January 17, 2019

RIGHT 10K: Blazing a trail to health care’s future

By Susan Buckles susanbuckles

Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a […]

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Tags: Center for Individualized Medicine, Eric Matey, genetics, Jessica Wright, pharmacogenomics, RIGHT 10K study


January 10, 2019

Gene therapy: potential and pitfalls

By Susan Buckles susanbuckles

Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]

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Tags: Center for Individualized Medicine, David Deyle, gene mutation, gene therapy, Saad Kenderian


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