Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Innovations

Exciting new things. Not a catch-all for all research.

February 20, 2020

Restoring function with larynx transplantation

By Jennifer Schutz Jennifer Schutz

Mayo Clinic has launched a first of its kind regenerative transplant program aimed at restoring function for people who need their larynx, or voice box, removed. In the United States about 60,000 people are living without a larynx, due to disease or trauma. The larynx is a segment of the respiratory tract located in the […]

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Tags: Center for Regenerative Medicine, D. Eric Steidley, David Lott, larynx transplant, regenerative medicine, transplant


February 18, 2020

Mayo researchers studying ‘promising’ new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy Susan Murphy

A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]

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Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine


February 17, 2020

AI system helps individualize treatment people diagnosed with depression

By Advancing the Science contributor Advancing the Science contributor

When searching for an exact diagnosis through a myriad of complex and serious factors spread across millions of data points, it helps to have a powerful magnifying glass — and another expert point of view. Enter Arjun Athreya, Ph.D., an engineer by trade who has a knack for bringing together data science algorithms and computing […]

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Tags: Arjun Athreya, artificial intelligence, collaboration, data science, depression, individualized medicine, pharmacology, precision medicine, team science, University of Illinois Urbana-Champaign, William Bobo


January 30, 2020

A breakthrough in distinguishing benign adrenal tumors from cancerous ones

By Advancing the Science contributor Advancing the Science contributor

By Christoph Bahn Approximately 80 million CT scans are performed in the United States every year. Adrenal tumors are found incidentally in about 5% of these scans. Most of these tumors will turn out to be benign, but a small fraction will be adrenal cortical carcinoma, a type of cancer with high mortality and frequent recurrence; even for […]

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Tags: adrenal tumors, biomarkers, biopsy, cancer, clinical research, CT, endocrine cancer, endocrinology, epidemiology, hormones, Irina Bancos, Mayo Clinic Laboratories


January 13, 2020

Top ways regenerative medicine is advancing the health care of tomorrow for patients today

By Susan Buckles Susan Buckles

Regenerative medicine accelerated from the bench into the practice in new ways in 2019, ushering in an era of care focused on the body’s amazing ability to heal itself. Bolstered by robust research, Mayo Clinic is at the forefront of delivering new therapies that restore form and function to diseased cells, tissues, or organs — […]

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Tags: Andre Terzic, cancer, CAR-T, Center for Regenerative Medicine, clinical trials, immunotherapy, larynx transplant, maternal and fetal medicine, Regenerative Medicine Minnesota, spinal cord injury, transplant


December 23, 2019

Teaching a computer to read a kidney biopsy

By Advancing the Science contributor Advancing the Science contributor

Mayo researchers say patients will benefit from faster, more accurate reads By Jay Furst Artificial intelligence may never replace human insight, expertise and judgment. Then again, no one’s complaining about how it can help, especially when it comes to analyzing kidney biopsies, a laborious process that’s an intricate mix of art and science. Accurate and […]

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Tags: Aleksandar Denic, artificial intelligence, Byron Smith, collaboration, kidney disease, kidney transplant, Mariam Priya Alexander, Mark Stegall, nephrology, pathology, team science, transplant


December 17, 2019

Mayo Clinic innovator inspired by patients, surgical experience to improve medical devices

By Advancing the Science contributor Advancing the Science contributor

By Sandy Shortridge Like so many Mayo Clinic staff members, Kenneth Dye has been inspired by Mayo Clinic patients throughout his career. In Dye’s case, conversations with two prolific inventors — while they were patients at Mayo Clinic — sparked his interest in finding ways to improve medical devices. The inventors encouraged Dye to pursue his interest […]

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Tags: anesthesiology, artificial heart, biotechnology, cardiology, Kenneth Dye, medical innovation, Neil Feinglass, patient safety, surgery, surgical outcomes


November 27, 2019

Pediatric Advisory Board gives kids a voice in research that affects them

By Advancing the Science contributor Advancing the Science contributor

A group of young people make up Mayo Clinic’s unique Pediatric Advisory Board, offering ideas about recruiting and communicating with research participants.

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Tags: Center for Clinical and Translational Science, community engagement, Megan Allyse, Miguel Valdez Soto, Pediatric Advisory Board


November 14, 2019

Late relapse for breast cancer patients: Scientists work to predict risk

By Advancing the Science contributor Advancing the Science contributor

By Sara Nick Many breast cancer patients develop recurrence years after the original diagnosis, despite following a long-term medication protocol after initial treatment. Mayo Clinic scientists are taking a closer look at which factors contribute to risk of recurrence, including the subtype of cancer patients have. “Understanding which patients are still at risk of late […]

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Tags: breast cancer, E. Aubrey Thompson, genomics, Mayo Clinic Cancer Center, Saranya Chumsri


November 12, 2019

Gerstner Regenerative Medicine Initiative: Tracking outcomes and supporting clinical trials

By Jennifer Schutz Jennifer Schutz

One of the challenges of integrating regenerative medicine into daily patient care is that it is so new, there is not a lot of available data to consider when determining best practices. A recent grant will help track information on how patient do after clinical trials. The Gerstner Regenerative Medicine Initiative, funded through a grant from […]

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Tags: Center for Regenerative Medicine, Gerstner Regenerative Medicine Initiative, osteoarthritis, regenerative medicine, stem cells


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