Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Innovations

Exciting new things. Not a catch-all for all research.

March 21, 2019

Colon cancer: a new era in cancer screening and detection

By Susan Buckles susanbuckles

March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]

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Tags: Cancer genomics, Center for Individualized Medicine, colon cancer, Dr. Niloy "Jewel" Samadder, Hereditary cancer, Inherited cancer, Lynch syndrome, Mayo Clinic Arizona, precision medicine


March 13, 2019

Business innovation with an eye on improving vision

By Susan Buckles susanbuckles

If eyes are the window to the world, Timothy W. Olsen, M.D. is building high performance window frames. With a passion for restoring vision, the ophthalmologist set sights on developing and bringing to market a first-of-its-kind device for treating age-related macular degeneration. The synergies around the Destination Medical Center economic initiative and Mayo Clinic’s research […]

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Tags: age-related macular degeneration, Destination Medical Center, life sciences discovery, medical innovation, ophthalmology, Timothy W. Olsen


March 7, 2019

What do Yellowstone rocks teach us about kidney stones

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog. Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized […]

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Tags: Center for Individualized Medicine, kidney stones, medical research, microbiome, Nicholas Chia


February 11, 2019

Zooming in on Colon Polyps

By Kate Ledger k8ledger

Gastroenterologists agree that removing a colorectal polyp is an important step in preventing colon cancer, but one challenge has been excising polyps that are large, particularly those that are flat and more than an inch in diameter. A recently introduced minimally-invasive approach, called endoscopic mucosal resection, or EMR, facilitates the removal of large polyps without […]

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Tags: cancer prevention, colon cancer, colon polyp, gastroenterology, Mayo Clinic Cancer Center, Michael Wallace


January 22, 2019

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Advancing the Science contributor advancingthescience

By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can […]

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Tags: cancer, Center for Individualized Medicine, individualized medicine, Mayo Clinic Cancer Center, personalized medicine, pharmacogenomics, Robert Diasio


January 17, 2019

RIGHT 10K: Blazing a trail to health care’s future

By Susan Buckles susanbuckles

Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a […]

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Tags: Center for Individualized Medicine, Eric Matey, genetics, Jessica Wright, pharmacogenomics, RIGHT 10K study


January 10, 2019

Gene therapy: potential and pitfalls

By Susan Buckles susanbuckles

Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]

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Tags: Center for Individualized Medicine, David Deyle, gene mutation, gene therapy, Saad Kenderian


January 3, 2019

A vaccine to prevent breast cancer? It’s worth a shot

By Advancing the Science contributor advancingthescience

Each fall, millions of Americans roll up their sleeves for a flu shot, grateful for the quick pinch that may save them from the misery the flu can bring. In the not-too-distant future, there may be a poke with a much bigger payout. Scientists at Mayo Clinic and elsewhere are working on vaccines that could […]

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Tags: breast cancer, immunotherapy, Keith Knutson, Mayo Clinic Cancer Center, ovarian cancer


December 20, 2018

Discovery advances potential individualized treatment for mesothelioma

By Susan Buckles susanbuckles

This article originally ran on the Center for Individualized Medicine blog on November 26, 2018 Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. […]

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Tags: Aaron Mansfield, cancer, Center for Individualized Medicine, George Vasmatzis, mesothelioma


December 18, 2018

Study shows better outcomes for women treated for uterine fibroids with UAE

By Advancing the Science contributor advancingthescience

A multicenter study led by Mayo Clinic researchers shows that women who undergo uterine artery embolization (UAE) for symptomatic uterine fibroids are less likely to need a second procedure compared to women who were treated by magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS). The results are published online in the American Journal of Obstetrics and […]

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Tags: collaboration, gynecology, Shannon Laughlin-Tommaso, women's health


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