Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Innovations

Exciting new things. Not a catch-all for all research.

January 17, 2023

‘Walleye Tank’ competition reels in entrepreneurs and innovators

By Caitlin Doran Caitlin Doran (@caityrosey)

The recent “Walleye Tank: Ice Fishing Edition” brought together innovators and entrepreneurs from across Minnesota to pitch their ideas to win prizes to fund the continuing development of their projects. Innovators from Mayo Clinic and across Minnesota gathered on Dec. 2 to compete in “Walleye Tank: Ice Fishing Edition,” pitching their ideas to a panel […]

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Tags: artificial intelligence, cancer, Center for Clinical and Translational Science, Diogo Moniz Garcia, entrepreneurship, Mayo Clinic Platform, Office of Entrepreneurship, Rena Hale


January 3, 2023

Measuring resiliency in hospital quality performance during the pandemic era

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Hospital quality rankings and ratings, including the U.S. News & World Report’s Best Hospitals and Centers for Medicare & Medicaid Services (CMS) Overall Hospital Star Ratings have faced an unusual challenge in recent years:  To what extent should hospitals be held accountable for traditional quality measure performance, given the unknown effects of the COVID-19 pandemic […]

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Tags: Ben Pollock, Center for the Science of Health Care Delivery, Centers for Medicare & Medicaid Services, COVID-19, health sciences research, quality improvement, resiliency


December 29, 2022

Top 10 (ish) posts of 2022

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

As we count down to 2023, the time is right to recap some of the hot topics of the last year. Spots 9 and 10 were occupied by three stories, so we went with the top 11. If you’re short on time as well as conversation starters, these articles could provide just the thing you […]

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Tags: artificial intelligence, big data, biomedical research, Center for Individualized Medicine, Center for the Science of Health Care Delivery, COVID-19, diagnostic odyssey, DNA, environment, epidemiology, genetic testing, gut health


November 24, 2022

The future will be personalized: Accelerating microbiome research

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings to […]

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Tags: arthritis, C. diff, cancer, Center for Individualized Medicine, colitis, colorectal cancer, diabetes, endometrial cancer, Francis Farraye, gastroenterology, gut health, gynecology


November 17, 2022

Focus on community practice: Real-world research fuels better outcomes

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

It’s a Catch-22. You can’t improve community practice without evidence-based research, but it’s challenging to incorporate research into a busy primary care practice. And there’s a paucity of researchers devoted to primary care. “We’re busy seeing patients and trying to deliver the best care possible. It’s hard to find time to pause, step back and […]

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Tags: Center for Clinical and Translational Science, Center for Health Equity and Community Engagement Research, community engagement, emergency medicine, geriatrics, health disparities, multiple chronic conditions, palliative care, pragmatic trials, Prathibha Varkey, primary care, Rozalina McCoy


October 4, 2022

AI enables early identification, intervention in debilitating lung disease

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

In a new study published in Nature Medicine, Mayo Clinic and several research collaborators from across the U.S., describe a successful new artificial intelligence, or AI, -enabled tool to identify idiopathic pulmonary fibrosis, also called IPF, before patients have recognizable symptoms. This tool could alert a patient’s primary care team of a probable IPF diagnosis […]

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Tags: artificial intelligence, big data, Center for the Science of Health Care Delivery, clinical informatics, collaboration, idiopathic pulmonary fibrosis, patient reported outcomes, pulmonary and critical care medicine, shared decision making, team science


August 30, 2022

Biomanufacturing 101: Understanding a new era of therapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Advancing discoveries such as cellular therapies from clinical trials to commercial therapy is a cornerstone of Mayo Clinic’s strategic emphasis on biomanufacturing. The long-term vision is to provide new cures for patients with unmet needs. “Biomanufacturing is a type of manufacturing that utilizes sources from the human body — cells, blood, enzymes, tissues, genes or […]

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Tags: biologics, biomanufacturing, CAR-T cell therapy, Center for Regenerative Medicine, Julie Allickson, regnerative biotherapeutics


August 2, 2022

Addressing the challenges of chimeric antigen receptor-T cell therapy

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]

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Tags: cancer therapy, CAR-T cell therapy, Center for Regenerative Medicine, Hong Qin, regenerative immunotherapy, Saad Kenderian


July 28, 2022

Bringing regenerative technology of the future to patients today

By Susan Buckles Susan Buckles (@susanbuckles)

“The sky’s the limit,” “possibility” and “potential cure for disease” are aspirational ways Mayo Clinic physicians and scientists described regenerative medicine in a recent virtual presentation at the World Stem Cell Summit 2022. Mayo’s panel discussion showcased how it is advancing regenerative medicine through industry collaborations that accelerate scientific discoveries to early stage clinical trials. […]

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Tags: 3D printing, Abba Zubair, biomanufacturing, Center for Regenerative Medicine, David Lott, Julie Allickson, Saranya Wyles, tissue engineering, World Stem Cell Summit


June 15, 2022

Research News Roundup — May 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In May, researchers from Mayo Clinic reported gains in understanding of the benefit of AI-enabled ECGs, including from wearable devices. They made strides towards more effective treatment of non-Hodgkin lymphoma and nonmetastatic gastroesophageal cancer. And in news many people can use, investigators report on the results of a survey linked to the Mayo Clinic Diet. […]

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Tags: AFib, artificial intelligence, atrial fibrillation, CAR-T cell therapy, Center for the Science of Health Care Delivery, clinical trials, cognitive impairment, EKG, electrocardiogram, esophageal cancer, gastric cancer, gastroesophageal cancer


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