Innovations
Exciting new things. Not a catch-all for all research.
March 21, 2019
Colon cancer: a new era in cancer screening and detection
March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]
Tags: Cancer genomics, Center for Individualized Medicine, colon cancer, Dr. Niloy "Jewel" Samadder, Hereditary cancer, Inherited cancer, Lynch syndrome, Mayo Clinic Arizona, precision medicine
March 13, 2019
Business innovation with an eye on improving vision
If eyes are the window to the world, Timothy W. Olsen, M.D. is building high performance window frames. With a passion for restoring vision, the ophthalmologist set sights on developing and bringing to market a first-of-its-kind device for treating age-related macular degeneration. The synergies around the Destination Medical Center economic initiative and Mayo Clinic’s research […]
Tags: age-related macular degeneration, Destination Medical Center, life sciences discovery, medical innovation, ophthalmology, Timothy W. Olsen
March 7, 2019
What do Yellowstone rocks teach us about kidney stones
This article originally appeared on the Center for Individualized Medicine blog. Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized […]
Tags: Center for Individualized Medicine, kidney stones, medical research, microbiome, Nicholas Chia
February 11, 2019
By Kate Ledger 
Gastroenterologists agree that removing a colorectal polyp is an important step in preventing colon cancer, but one challenge has been excising polyps that are large, particularly those that are flat and more than an inch in diameter. A recently introduced minimally-invasive approach, called endoscopic mucosal resection, or EMR, facilitates the removal of large polyps without […]
Tags: cancer prevention, colon cancer, colon polyp, gastroenterology, Mayo Clinic Cancer Center, Michael Wallace
January 22, 2019
Pharmacogenomics: finding the right drug, dose for cancer therapy
By Advancing the Science contributor
By Sharon Rosen Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can […]
Tags: cancer, Center for Individualized Medicine, individualized medicine, Mayo Clinic Cancer Center, personalized medicine, pharmacogenomics, Robert Diasio
January 17, 2019
RIGHT 10K: Blazing a trail to health care’s future
Article by Barbara Toman This article originally appeared on the Center for Individualized Medicine blog Mayo Clinic’s Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn’t involve running shoes but nevertheless is paving the way to prescribing medications matched to a […]
Tags: Center for Individualized Medicine, Eric Matey, genetics, Jessica Wright, pharmacogenomics, RIGHT 10K study
January 10, 2019
Gene therapy: potential and pitfalls
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]
Tags: Center for Individualized Medicine, David Deyle, gene mutation, gene therapy, Saad Kenderian
January 3, 2019
A vaccine to prevent breast cancer? It’s worth a shot
By Advancing the Science contributor
Each fall, millions of Americans roll up their sleeves for a flu shot, grateful for the quick pinch that may save them from the misery the flu can bring. In the not-too-distant future, there may be a poke with a much bigger payout. Scientists at Mayo Clinic and elsewhere are working on vaccines that could […]
Tags: breast cancer, immunotherapy, Keith Knutson, Mayo Clinic Cancer Center, ovarian cancer
December 20, 2018
Discovery advances potential individualized treatment for mesothelioma
This article originally ran on the Center for Individualized Medicine blog on November 26, 2018 Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. […]
Tags: Aaron Mansfield, cancer, Center for Individualized Medicine, George Vasmatzis, mesothelioma
December 18, 2018
Study shows better outcomes for women treated for uterine fibroids with UAE
By Advancing the Science contributor
A multicenter study led by Mayo Clinic researchers shows that women who undergo uterine artery embolization (UAE) for symptomatic uterine fibroids are less likely to need a second procedure compared to women who were treated by magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS). The results are published online in the American Journal of Obstetrics and […]
Tags: collaboration, gynecology, Shannon Laughlin-Tommaso, women's health