News
Mayo Clinic research and research education news
October 4, 2022
AI enables early identification, intervention in debilitating lung disease
In a new study published in Nature Medicine, Mayo Clinic and several research collaborators from across the U.S., describe a successful new artificial intelligence, or AI, -enabled tool to identify idiopathic pulmonary fibrosis, also called IPF, before patients have recognizable symptoms. This tool could alert a patient’s primary care team of a probable IPF diagnosis […]
Tags: artificial intelligence, big data, Center for the Science of Health Care Delivery, clinical informatics, collaboration, idiopathic pulmonary fibrosis, patient reported outcomes, pulmonary and critical care medicine, shared decision making, team science
September 29, 2022
Mayo Clinic study indicates rural US counties have higher diabetes-related deaths
In a new study, Mayo Clinic researchers identified substantial health disparities in rural versus urban areas in diabetes-related deaths, with other disparities based on gender. Using nationwide data from the Centers for Disease Control and Prevention, the researchers examined rates and trends from 1999 to 2018, in diabetes-related deaths among adults based on county urbanization, […]
Tags: Adrian Vella, diabetes, endocrinology, epidemiology, health disparities, heart health, multiple chronic conditions, rural health care, Sagar Dugani
September 27, 2022
Physician-scientist investigates dual CAR-T cell therapy for multiple myeloma cancer
By Susan Murphy 
Leo Sakemura, M.D., Ph.D., a physician-scientist in Mayo Clinic’s Division of Hematology, is working to advance immunotherapy efficacy in multiple myeloma by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment. Dr. Sakemura’s previous […]
Tags: cancer genomics, cancer research, CAR-T cell therapy, Center for Individualized Medicine, hematology, immunotherapy, Leo Sakemura, metabolomics, multiple myeloma
September 26, 2022
Meet Khushboo Gala, M.B.B.S. — Finding fulfillment in helping others
By Advancing the Science contributor
Khushboo S. Gala, M.B.B.S. is a gastroenterology fellow in the Mayo Clinic School of Graduate Medical Education. She cares for patients and conducts clinical research at Mayo Clinic in Rochester, Minnesota. Dr. Gala recently became a Kern Health Care Delivery Scholar, commencing a mentored training and research program within the Mayo Clinic Robert D. and […]
Tags: Andres Acosta, Center for the Science of Health Care Delivery, Juan Brito Campana, Kern Health Care Delivery Scholars, Khushboo Gala, Mayo Clinic School of Graduate Medical Education, obesity, Victor Montori
September 22, 2022
A preclinical step toward treating chronic dry mouth
Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]
Tags: basic science, Center for Regenerative Medicine, discovery research, dry mouth, head and neck cancer, Jeffrey Janus, medical research, Nagarajan Kannan, otolaryngology, quality of life, radiation therapy, salivary glands
September 21, 2022
Maintaining quality care for patients with ALS — Lessons from the pandemic
By Advancing the Science contributor
By Susan Barber Lindquist The efficiency and effectiveness of telemedicine exploded during the COVID-19 pandemic. For patients with Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis or ALS, telemedicine always has been an important piece of their medical care. A recent study in Neurology by Mayo Clinic researchers offers one more proof point. Tests […]
Tags: ALS, amyotrophic lateral sclerosis, clinical trials, COVID-19, Lou Gehrig's disease, Nathan Staff, neurology, remote patient monitoring, telehealth, telemedicine
September 20, 2022
Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care
Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic yield in people with […]
Tags: Center for Individualized Medicine, genomics, kidney disease
September 15, 2022
Meet Gustavo Cortes Puentes, M.D. — Compassionate Clinician Scientist
By Advancing the Science contributor
Gustavo Cortes Puentes, M.D. (@DrivingPressure), is a pulmonary and critical care specialist at Mayo Clinic in Rochester, Minnesota. Originally from Colombia, he came to Mayo by way of an internal medical residency with the University of Minnesota Medical School in Minneapolis, following a research scholar appointment during which he studied pulmonary mechanics and acute respiratory […]
Tags: Caroline Davidge-Pitts, Cassie Kennedy, Center for Health Equity and Community Engagement Research, Center for the Science of Health Care Delivery, Cesar Gonzalez, diversity, Gustavo Cortes Puentes, health disparities, Kaiser Lim, Kern Health Care Delivery Scholars, pulmonary and critical care medicine, Sean Phelan
September 13, 2022
Mayo Clinic study reveals aging speeds genomic mutations in brain
Somatic mutations naturally occur in cells throughout human development and during aging. However, it has yet to be determined whether the frequency of somatic mutations in the population are a contributing factor to the cause of neuropsychiatric disorders, cancers, and various diseases. Alexej Abyzov, Ph.D., a Mayo Clinic genomics researcher, seeks to gain a better […]
Tags: brain, Center for Individualized Medicine, genomics, neurology
September 8, 2022
A new name for Center for Regenerative Medicine
Mayo Clinic’s Center for Regenerative Medicine has been renamed the Center for Regenerative Biotherapeutics. The name change reflects Mayo’s new strategic focus: manufacturing next-generation biotherapeutics for patients. The new name emphasizes how regenerative medicine at Mayo Clinic has evolved to advance groundbreaking discoveries toward curative products — biotherapeutics — for patients. The Center for Regenerative […]
Tags: Cell therapy, Center for Regenerative Biotherapeutics, gene therapy, Julie Allickson