Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

republished

January 31, 2023

Training scientists to rebuild health

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Experts predict that regenerative medicine will transform clinical practice. A conservative estimate is that 20% of future medical and surgical solutions will involve regenerative solutions. Regenerative medicine shifts the focus of medicine from fighting disease to rebuilding health. Regenerative medicine could improve human health span — the number of disease-free years — so a person’s […]

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Tags: Andre Terzic, Armin Garmany, Center for Regenerative Medicine, Douglas Brownfield, Isobel Scarisbrick, Mayo Clinic Graduate School of Biomedical Sciences, medical research education, Nathaniel Blackwell, research education, Shan Gao, Stijn De Langhe


January 12, 2023

Studies show resiliency training may help kids’ well-being, decision-making skills, more

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Mayo Clinic students and researchers are studying whether resiliency training can help children and adults live healthier, more productive lives.

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Tags: anxiety, Catherine (Kit) Knier, Center for Clinical and Translational Science, Chris Pierret, depression, education, health equity, Lisa Schimmenti, Mayo Clinic Graduate School of Biomedical Sciences, medical research education, Medical Scientist Training Program, mental health


November 24, 2022

The future will be personalized: Accelerating microbiome research

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings to […]

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Tags: arthritis, C. diff, cancer, Center for Individualized Medicine, colitis, colorectal cancer, diabetes, endometrial cancer, Francis Farraye, gastroenterology, gut health, gynecology


November 18, 2022

CDC releases updated guideline for prescribing opioids for pain

By Colette Gallagher Colette Gallagher (@colettegallagher)

On Nov. 4, the Centers for Disease Control and Prevention (CDC) released updated and expanded recommendations for clinicians providing pain care for adult outpatients with short- and long-term pain. These clinical recommendations, published in the CDC Clinical Practice Guideline for Prescribing Opioids for Pain, will help clinicians work with their patients to ensure the safest and […]

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Tags: Center for the Science of Health Care Delivery, Centers for Disease Control and Prevention, Elizabeth Habermann, Halena Gazelka, opioids, pain management, practice improvement


November 17, 2022

Focus on community practice: Real-world research fuels better outcomes

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

It’s a Catch-22. You can’t improve community practice without evidence-based research, but it’s challenging to incorporate research into a busy primary care practice. And there’s a paucity of researchers devoted to primary care. “We’re busy seeing patients and trying to deliver the best care possible. It’s hard to find time to pause, step back and […]

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Tags: Center for Clinical and Translational Science, Center for Health Equity and Community Engagement Research, community engagement, emergency medicine, geriatrics, health disparities, multiple chronic conditions, palliative care, pragmatic trials, Prathibha Varkey, primary care, Rozalina McCoy


October 11, 2022

Meet Surbhi Shah, M.B.B.S., M.D. – Driven to learn, incorporating learning to improve care

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Surbhi Shah, M.B.B.S., M.D., is a hematologist at Mayo Clinic in Arizona., whose focus is on treating patients with non-cancerous blood disorders. In addition to her clinical duties, Dr. Shah dedicates time both to learning, and to sharing what she learns – through teaching, mentoring, presentation and publication. To expand her own understanding and increase Mayo’s […]

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Tags: anticoagulant, blood disease, Center for the Science of Health Care Delivery, clinical research, Fadi Shamoun, hematology, hemophilia, Jennifer Ridgeway, Kern Health Care Delivery Scholars, learning health system, medical innovation, mentorship


September 27, 2022

Physician-scientist investigates dual CAR-T cell therapy for multiple myeloma cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Leo Sakemura, M.D., Ph.D., a physician-scientist in Mayo Clinic’s Division of Hematology, is working to advance immunotherapy efficacy in multiple myeloma by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment.  Dr. Sakemura’s previous […]

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Tags: cancer genomics, cancer research, CAR-T cell therapy, Center for Individualized Medicine, hematology, immunotherapy, Leo Sakemura, metabolomics, multiple myeloma


September 26, 2022

Meet Khushboo Gala, M.B.B.S. — Finding fulfillment in helping others

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Khushboo S. Gala, M.B.B.S. is a gastroenterology fellow in the Mayo Clinic School of Graduate Medical Education. She cares for patients and conducts clinical research at Mayo Clinic in Rochester, Minnesota. Dr. Gala recently became a Kern Health Care Delivery Scholar, commencing a mentored training and research program within the Mayo Clinic Robert D. and […]

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Tags: Andres Acosta, Center for the Science of Health Care Delivery, Juan Brito Campana, Kern Health Care Delivery Scholars, Khushboo Gala, Mayo Clinic School of Graduate Medical Education, obesity, Victor Montori


September 22, 2022

A preclinical step toward treating chronic dry mouth

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]

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Tags: basic science, Center for Regenerative Medicine, discovery research, dry mouth, head and neck cancer, Jeffrey Janus, medical research, Nagarajan Kannan, otolaryngology, quality of life, radiation therapy, salivary glands


September 15, 2022

Meet Gustavo Cortes Puentes, M.D. — Compassionate Clinician Scientist

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Gustavo Cortes Puentes, M.D. (@DrivingPressure), is a pulmonary and critical care specialist at Mayo Clinic in Rochester, Minnesota. Originally from Colombia, he came to Mayo by way of an internal medical residency with the University of Minnesota Medical School in Minneapolis, following a research scholar appointment during which he studied pulmonary mechanics and acute respiratory […]

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Tags: Caroline Davidge-Pitts, Cassie Kennedy, Center for Health Equity and Community Engagement Research, Center for the Science of Health Care Delivery, Cesar Gonzalez, diversity, Gustavo Cortes Puentes, health disparities, Kaiser Lim, Kern Health Care Delivery Scholars, pulmonary and critical care medicine, Sean Phelan


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