Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

republished

June 28, 2022

Mayo Clinic patient grateful after genetic test leads to unexpected, early detection of colon cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Alejandro Mirazo, 56, never imagined his genetic test results would reveal a hereditary link to cancer, or that his findings would potentially save his life. He had participated in a preemptive DNA research sequencing study for Mayo Clinic’s Center for Individualized Medicine in fall 2021 solely to contribute to medical research. As a Mexican American, he also […]

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Tags: Center for Individualized Medicine, colon cancer, genetic testing, genomics, Konstantinos Lazaridis, Niloy "Jewel" Samadder


June 22, 2022

Study indicates gut microbiome, host gene affect gastrointestinal disorders

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Nature Microbiology, researchers demonstrated the power of integrating the microbiome and host gene expression data to provide insights into their combined role in gastrointestinal diseases. The microbiome consists of all microbes in the gut including bacteria, fungi, and viruses. This study focused on bacteria. “We identified a common set of […]

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Tags: Center for Individualized Medicine, gastroenterology


June 21, 2022

What’s behind patient requests for stem cells?

By Susan Buckles Susan Buckles (@susanbuckles)

In one of the first studies of its kind, Mayo Clinic analyzed a large group of patients to understand their motivations for seeking stem cell therapies and whether expectations are grounded in science. The findings could help health care professionals cut through misleading claims and better counsel patients. This research by Jennifer Arthurs; Zubin Master, […]

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Tags: biomedical ethics, Center for Regenerative Medicine, clinical research, Jennifer Arthurs, orthopedics, Shane Shapiro, stem cells, Zubin Master


June 16, 2022

Native American’s genetic test results at Mayo Clinic reveal surprise lineage to ancient tribe   

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic working to advance health equity among Native Americans, Alaska Natives Schyler Martin, a member of the Munsee Band of Mohicans in Minnesota, was surprised and excited when his recent Mayo Clinic genetic test results revealed he has distinctive DNA lineage to an ancient group of Native Americans known as the Beringians. According to […]

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Tags: Center for Individualized Medicine, DNA, genetic testing, genomics


June 14, 2022

Dawn’s journey: Overcoming a near-zero survival rate

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Dawn Botsford was sitting in a chair at the hair salon in the fall of 2011 when her hairdresser commented on a spot on the top of her head. It was bug season in North Dakota, so Dawn didn’t think much of it. “When I told my hairdresser that, she said, ‘I really think you […]

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Tags: cancer, clinical trials, dermatology, Eric Moore, immunotherapy, Mayo Clinic Cancer Center, melanoma, oncology, Robert McWilliams, skin cancer, Stephen Cassivi, Svetomir Markovic


June 9, 2022

Biomedical innovators pitch ideas at Roadrunner Sprint competition

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Mayo Clinic innovations and innovators were highlighted during the second annual Roadrunner Sprint, which was held May 5 at the Arizona State University Health Futures Center Auditorium. The Roadrunner Sprint is organized and sponsored by the Mayo Clinic Office of Entrepreneurship. In this “Shark Tank”-like event, 10 teams of Mayo staff entrepreneurs pitched their solutions to […]

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Tags: Ami Shah, Anu Sreedhar, Center for Clinical and Translational Science, Dharmendra Patel, entrepreneurship, Office of Entrepreneurship, Richard Gray


May 31, 2022

Mayo research using DNA to catch cancer, other medical conditions earlier

By Adam Harringa Adam Harringa (@harringaadam)

What would happen if a certain percentage of serious medical conditions, including cancer diagnoses, were found significantly earlier by studying the entire genome of patients’ DNA? How would their quality of life improve, and how many fewer cancer deaths would there be each year? That’s what a group of Mayo Clinic scientists and clinicians aim […]

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Tags: Bijan Borah, breast cancer, Center for Individualized Medicine, Center for the Science of Health Care Delivery, Centers for Disease Control and Prevention, DNA, genome, genomics, health disparities, hereditary cancer, hereditary diseases, hypercholesterolemia


May 26, 2022

Neuroscience research mentors pay it forward

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

As a medical student in Mexico, Paola Suarez-Meade, M.D., was confident she wanted a career that included research along with clinical work. But among her teachers, the most common career paths involved making a choice: either treat patients or study disease. A fascination with stem cells prompted her to seek out a research stint in the […]

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Tags: Alfredo Quinones-Hinojosa, Brain Tumor Stem Cell Laboratory, Emily Norton, glioblastoma, Hugo Guerrero-Cazares, Kaisorn Chaichana, Mayo Clinic Graduate School of Biomedical Sciences, mentorship, neurologic surgery, neurology, Paola Suarez-Meade, Paula Valentina Schiapparelli


May 23, 2022

Saranya Wyles: Regenerating damaged skin

By Susan Buckles Susan Buckles (@susanbuckles)

When she was just 8 years old, Saranya Wyles, M.D., Ph.D., would recite the stages of wound healing in Latin terms — rubor, tumor, calor, dolor and functio laesa— to her father at the dinner table. Decades later, that ingrained knowledge would be a cornerstone of her regenerative medicine research, education and practice at Mayo […]

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Tags: Center for Regenerative Medicine, dermatology, education, Saranya Wyles, senescent cells, skin regeneration, wound healing, zombie cells


May 19, 2022

How Mayo Clinic is finding new ways to care for more people with cancer

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Cheryl Willman, M.D., executive director, Mayo Clinic Cancer Programs, and director, Mayo Clinic Cancer Center. This story was originally published on the Mayo Clinic Cancer Center blog. As I reflect on my first months as executive director of Mayo Clinic Cancer Programs and director of Mayo Clinic Cancer Center, I am thrilled to lead one […]

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Tags: cancer, carbon ion therapy, Cheryl Willman, Mayo Clinic Cancer Center, messenger RNA, proton beam therapy, radiation therapy, virtual health care


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