Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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July 22, 2021 · Leave a Comment

Dr. Fischer wants to improve the health of children everywhere

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Philip (Phil) Fischer, M.D., says he’s always been interested in improving the health of children everywhere. He earned a diploma in tropical medicine and hygiene from the Liverpool School of Tropical Medicine in England to enhance his ability to do so. He worked at a medical center in what is now the Democratic Republic of […]

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Tags: gastroenterology, Mark Topazian, pediatric gastroenterology, pediatric research, Philip Fischer, Sheikh Shakhbout Medical Center


July 21, 2021 · Leave a Comment

Mayo researchers develop algorithm to predict rheumatoid arthritis disease activity

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine and Division of Rheumatology have developed a first-of-its-kind machine learning algorithm that can predict rheumatoid arthritis disease activity in a patient. The algorithm analyzes biochemical metabolites ― the product of the body’s metabolism ― in blood. “Having fast, reliable and scalable measures for predicting the clinical course of disease […]

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Tags: arthritis, artificial intelligence, autoimmune disorder, biomarkers, Center for Individualized Medicine, clinical research, genomics, Jaeyun Sung, John Davis III, metabolism, metabolomics, rheumatology


June 25, 2021 · Leave a Comment

Could regenerative medicine relieve neck, back pain?

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is looking to regenerative medicine as a potential long-term solution for degenerative disk disease that has for years eluded medical science. Millions of people in the U.S. are afflicted with chronic neck and back pain that often comes after years of wear and tear on the spine. Current treatments provide only temporary relief […]

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Tags: Center for Regenerative Medicine, degenerative disease, inflammation, mesenchymal stem cells, pain management, platelet rich plasma, Wenchun Qu


June 17, 2021 · Leave a Comment

Regenerative pipeline for spinal cord repair

By Sara Tiner Sara Tiner (@saratiner)

Mayo Clinic researchers are learning how stem cell therapy can treat neurodegenerative diseases. Mayo is among the first to study whether stem cell therapy might trigger healing for spinal cord injury. Research is ongoing in preclinical models, but it also has advanced from discovery science to early clinical trials. It’s a complex question, because different […]

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Tags: animal model, Anshit Goyal, Anthony Windebank, Bingkun Chen, Center for Regenerative Medicine, clinical trials, F. M. Moinuddin, medical research, mesenchymal stem cells, Mohamad Bydon, Mohammed Ali Alvi, spinal cord injury


June 8, 2021 · Leave a Comment

Mayo researchers articulate implications of Omic-Medicine Era – What needs to happen with each stakeholder?

By Colette Gallagher Colette Gallagher (@colettegallagher)

In the near future, genome sequencing, among other biological measures, will be as routine as X-rays and cholesterol testing. The challenge, though, will be accurately interpreting the vast amount of data and effectively using it to guide decisions about health care. In a position statement published in Hepatology, Mayo Clinic researchers layout perspectives of various stakeholders […]

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Tags: Arjun Athreya, artificial intelligence, big data, bioethics, Center for Individualized Medicine, data science, genetic testing, genetics, genomics, Konstantinos Lazaridis, patient experience, population health


June 2, 2021 · Leave a Comment

Researchers develop new technique to study ‘microcancers’ and screen cancer-fighting drugs

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

A team from the University of Illinois Urbana-Champaign’s Grainger College of Engineering and Mayo Clinic have developed a new technique for creating “microcancer” cell cultures. It allows researchers to form hundreds of microcancers in a high-throughput format using a small, microfabricated chip, enabling direct measurement of cell health or response to drugs. It also allows […]

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Tags: cancer research, Farhad Kosari, genomics, George Vasmatzis, Panos Anastasiadis, University of Illinois Urbana-Champaign


June 1, 2021 · Leave a Comment

On the shoulders of giants

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

When Essa Mohamed, Ph.D., heard Lewis Roberts, M.B., Ch.B., Ph.D., Mayo Clinic Division of Gastroenterology and Hepatology and the Peter and Frances Georgeson Professor of Gastroenterology Cancer Research, speak about liver cancer and hepatitis in the Somali population at a community meeting in 2011, he wanted to work with him. Three of Dr. Mohamed’s grandparents […]

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Tags: cardiovascular medicine, Center for Clinical and Translational Science, Essa Mohamed, gastroenterology, health disparities, Lewis Roberts, Mayo Clinic Graduate School of Biomedical Sciences, mentorship


May 24, 2021 · Leave a Comment

How regenerative medicine is advancing ALS research

By Susan Buckles Susan Buckles (@susanbuckles)

May is ALS Awareness Month, a time to reflect on the role of regenerative medicine research in advancing understanding and treatment of  amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease. This neurodegenerative disorder causes nerve cells in the brain and spinal cord to die, blocking signals to the muscles. That results in paralysis that robs […]

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Tags: ALS, amyotrophic lateral sclerosis, Anthony Windebank, Center for Regenerative Medicine, Lou Gehrig's disease, medical research, Nathan Staff


May 12, 2021 · Leave a Comment

Researchers explore health care disparities among people in minority communities

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In recognition of National Minority Health Month in April, a number of Mayo Clinic researchers participated in a virtual media briefing to discuss health care disparities that affect people who are members racial and ethnic minority populations in the United States. The experts addressed health education, early detection and control of disease complications. These are some of the […]

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Tags: Center for Clinical and Translational Science, Center for Health Equity and Community Engagement Research, Chyke Doubeni, community engagement, Edith Perez, health disparities, health equity, Michele Halyard, minority health, Sharonne Hayes


May 5, 2021 · Leave a Comment

Advancing regenerative medicine through a shared vocabulary

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine is defining an entirely new area of health care, spawning innovative advances across research, education and clinical practice. Like any emerging field, regenerative medicine is generating a plethora of new terms to learn. Mayo Clinic, a global leader in advancing this new field of medicine, contributed in establishing a standardized regenerative medicine lexicon. […]

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Tags: Andre Terzic, Center for Regenerative Medicine, medical education, research education, Zubin Master


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