Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

republished

September 17, 2020

Could regenerative medicine hold a key to understanding Alzheimer’s disease?

By Susan Buckles Susan Buckles

September is World Alzheimer’s Month, a time to raise awareness of research to unlock scientific mysteries around a disease that robs people of their memory, independence and ultimately their ability to think and reason. Focused on disease causes and cures, the Center for Regenerative Medicine is driving innovation as a collaborative partner in Mayo Clinic’s […]

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Tags: Alzheimer's disease, basic science, Center for Regenerative Medicine, dementia, discovery research, Guojun Bu, Melissa Murray, neurology, neurosciences, stem cells


September 16, 2020

Mayo Clinic research advances diagnostics to lead COVID-19 pandemic response

By Susan Murphy Susan Murphy

When COVID-19 spread across the U.S. in early March, Mayo Clinic’s Advanced Diagnostic Laboratory (ADL) urgently responded. Lab spaces were transitioned, staff reassigned and funding approvals were fast-tracked. Its goals were to accelerate research, development, translation and implementation of novel tests in order to discover life-saving treatments and diagnostics. “ADL houses a lab structure for […]

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Tags: Ann Moyer, antibodies, Benjamin Kipp, Bobbie Pritt, Center for Individualized Medicine, COVID-19, Department of Laboratory Medicine and Pathology, Dietrich Matern, Elitza Theel, genetics, genomics, John Mills


September 15, 2020

A regenerative alternative to hip replacement

By Susan Buckles Susan Buckles

Mikaili Robertson has a passion for playing college sports, so the second baseman was devastated when at age 18 he learned he needed a hip replacement. Worried his playing days might be over, he turned to Mayo Clinic and a surgery that — along with a cadaver tissue transplant — would tap the body’s power […]

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Tags: Aaron Krych, Center for Regenerative Medicine, hip replacement, osteonecrosis, Rafael Sierra, sickle cell disease


September 8, 2020

Stem cell research to improve hemodialysis

By Susan Buckles Susan Buckles

Stem cell therapy after angioplasty helps keep arteriovenous fistula blood vessels open, Mayo Clinic discovered in animal studies. An arteriovenous fistula is a passageway between an artery and a vein. This research, supported in part by the Mayo Clinic Center for Regenerative Medicine, provides a foundation on which someday patients with end stage renal disease, who […]

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Tags: Center for Regenerative Medicine, dialysis, hemodialysis, kidney disease, medical research, nephrology, Sanjay Misra, stem cell research


August 25, 2020

Rock star baby hitting all milestones after fetal surgery

By Susan Buckles Susan Buckles

The first peek at her baby during the 20 week ultrasound turned from excitement to concern for Hetty Mollert. “It was taking longer than I expected. I thought they were just being super in-depth about everything,” said Mollert, a first time mother-to-be from Madison, Wis. “Then we learned the devastating news. The ultrasound showed our […]

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Tags: Center for Regenerative Medicine, Chiari malformation, Edward Ahn, fetal surgery, hydrocephalus, maternal and fetal medicine, Mayo Clinic Proceedings, neurology, pediatric neurosurgery, Rodrigo Ruano, spina bifida


August 20, 2020

Could population genetic screening improve public health?

By Colette Gallagher Colette Gallagher

Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]

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Tags: breast cancer, cancer genomics, Center for Individualized Medicine, genetic testing, genetics, hereditary cancer, hereditary diseases, Lynch syndrome, Matthew Ferber, ovarian cancer, population health


August 18, 2020

Spotlighting 2020 graduates of Mayo Clinic College of Medicine and Science

By Susan Buckles Susan Buckles

Integrating new discoveries into patient care requires a workforce equipped to deliver the latest innovations. That’s why training the workforce of the future is a key objective of Mayo Clinic Education. Every year, Mayo Clinic’s College of Medicine and Science advances new graduates to their next levels of research and/or medical practice to address the […]

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Tags: Andre Terzic, Atta Behfar, CAR-T, Center for Regenerative Medicine, Karen Hedin, Mayo Clinic Alix School of Medicine, Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Medical Scientist Training Program, Rosalie Sterner, Saad Kenderian, Sinibaldo Romero Arocha


August 11, 2020

Expanding CAR T-cell therapy, welcoming Dr. Qin

By Susan Buckles Susan Buckles

The first time Hong Qin, M.D., Ph.D., saw images of how chimeric antigen receptor (CAR) T-cell therapy obliterated a tumor, he was captivated and inspired by this revolutionary treatment. As the new director of Regenerative Immunotherapies at Mayo Clinic in Florida, Dr. Qin and his team will play a pivotal role in accelerating the latest […]

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Tags: blood cancer, CAR T-cell therapy, CAR-T, Center for Regenerative Medicine, Hong Qin, immunotherapy, leukemia, Mayo Clinic Cancer Center, regenerative medicine


August 5, 2020

Regenerative patient consult service seeks to educate patients

By Susan Buckles Susan Buckles

Article by Charlene Martin-Lillie and Susan Buckles Advances in Regenerative Medicine hold promise for many patients as the therapeutic paradigm shifts from treating disease to restoring health. As this evolving field of medicine matures, information becomes increasingly available to the general public through multiple venues, mostly online. Terms such as “stem cells”, “exosomes”, and “regenerative […]

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Tags: bioethics, Center for Bioethics, Center for Regenerative Medicine, Shane Shapiro, Zubin Master


August 4, 2020

Phage therapy shows potential for treating prosthetic joint infections

By Susan Murphy Susan Murphy

Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research. The findings suggest phage therapy could provide a potential treatment for managing such infections, including those involving antibiotic-resistant microbes. The research is published in the July 23 issue of Clinical Infectious Diseases (CID). “The treatment for […]

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Tags: antibacterial resistance, bacteriophages, Center for Clinical and Translational Science, Center for Individualized Medicine, collaboration, Gina Suh, infectious disease, phage, prosthesis, research, Robin Patel


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