republished
February 20, 2020
Restoring function with larynx transplantation
Mayo Clinic has launched a first of its kind regenerative transplant program aimed at restoring function for people who need their larynx, or voice box, removed. In the United States about 60,000 people are living without a larynx, due to disease or trauma. The larynx is a segment of the respiratory tract located in the […]
Tags: Center for Regenerative Medicine, D. Eric Steidley, David Lott, larynx transplant, regenerative medicine, transplant
February 18, 2020
By Susan Murphy 
A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]
Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine
February 17, 2020
AI system helps individualize treatment people diagnosed with depression
By Advancing the Science contributor
When searching for an exact diagnosis through a myriad of complex and serious factors spread across millions of data points, it helps to have a powerful magnifying glass — and another expert point of view. Enter Arjun Athreya, Ph.D., an engineer by trade who has a knack for bringing together data science algorithms and computing […]
Tags: Arjun Athreya, artificial intelligence, collaboration, data science, depression, individualized medicine, pharmacology, precision medicine, team science, University of Illinois Urbana-Champaign, William Bobo
February 14, 2020
Filling hearts instead of test tubes
By Advancing the Science contributor
Editor’s note: This story is not about Mayo Clinic research, but rather about a part of a researcher’s life that builds hope in little hearts, and gives him joy. It’s 10 a.m. on a Thursday, and Merrick Ducharme is up to his elbows (OK, his wrists) in slime. The gooey, gluey mixture is not one […]
February 10, 2020
Research is advancing a regenerative solution for a quality of life-limiting complication of mesh-based surgical repairs for stress urinary incontinence and pelvic organ prolapse in women. While mesh-based surgical treatments are durable and provide symptom relief for a great number of patients, there is a risk of mesh complications following surgery, such as mesh exposure. […]
Tags: Cassandra Kisby, Center for Regenerative Medicine, John Occhino, regenerative medicine, urinary incontinence, vaginal prolapse, women's health
February 5, 2020
“I Just Didn’t Understand”: On a Mission to Cure ALS
By Advancing the Science contributor
By Barbara J. Toman For Veronique Belzil, Ph.D., the fight against amyotrophic lateral sclerosis (ALS) is personal. In 2000, while working as a psychologist in Canada, she watched her husband’s uncle succumb to the disease. “The progression was so fast and his condition was so sad,” she says. “I just didn’t understand how this could […]
Tags: ALS, amyotrophic lateral sclerosis, Center for Individualized Medicine, DNA, epigenetics, Lou Gehrig's disease, Veronique Belzil
January 31, 2020
How a love for learning inspired an investment in physicians of the future
By Advancing the Science contributor
Jay Alix grew up surrounded by an unlikely team of experts. That, and a supportive community, gave him a push that turned him into a world-class business leader. Now a member of the Mayo Clinic Board of Trustees, he’s sharing his legendary business acumen to help Mayo Clinic educate the next generation of physician-scientists and […]
Tags: Gianrico Farrugia, John Noseworthy, Mayo Clinic Alix School of Medicine, Mayo Clinic Model of Research, medical innovation, research, research education
January 30, 2020
A breakthrough in distinguishing benign adrenal tumors from cancerous ones
By Advancing the Science contributor
By Christoph Bahn Approximately 80 million CT scans are performed in the United States every year. Adrenal tumors are found incidentally in about 5% of these scans. Most of these tumors will turn out to be benign, but a small fraction will be adrenal cortical carcinoma, a type of cancer with high mortality and frequent recurrence; even for […]
Tags: adrenal tumors, biomarkers, biopsy, cancer, clinical research, CT, endocrine cancer, endocrinology, epidemiology, hormones, Irina Bancos, Mayo Clinic Laboratories
January 27, 2020
Neuro regeneration for chemo brain: Mi-Hyeon Jang, Ph.D.
Cognitive dysfunction, sometimes called “chemo brain,” stemming from chemotherapy is a major adverse condition affecting approximately 14 million cancer patients and survivors in the United States. Although chemo brain has been widely reported by patients and clinicians, the cause of concentration and memory problems in cancer patients is not well understood. Mayo Clinic researchers are […]
Tags: cancer, Center for Regenerative Medicine, chemo brain, chemotherapy, Mayo Clinic Cancer Center, Mi-Hyeon Jang, neuroregeneration, regenerative medicine, Regenerative Medicine Minnesota, stem cells
January 23, 2020
Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also could lead to new strategies for treating diseases of the central nervous […]
Tags: Alzheimer's disease, autoimmune disorder, basic science, Center for Regenerative Medicine, demyelination, discovery research, Isobel Scarisbrick, multiple sclerosis, neurology, schizophrenia, spinal cord injury