Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

republished

April 2, 2020

From Mayo Clinic patient to first regenerative sciences graduate

By Jennifer Schutz Jennifer Schutz

When Chris Paradise graduates from the Mayo Clinic Graduate School of Biomedical Sciences in May, it will be yet another important milestone in his lifelong relationship with Mayo Clinic. The one time Mayo patient and child of a Mayo Clinic nurse will be the first student to graduate from the doctoral research training program known as the […]

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Tags: Chris Paradise, Dr. Andre van Wijnen, Mayo Clinic Center for Regenerative Medicine, regenerative medicine, Regenerative Sciences Training Program, RSTP


March 24, 2020

Individualized care for psychiatric disorders — Mayo Clinic Biobank + genetic testing could pave the way

By Susan Murphy Susan Murphy

By Sharon Rosen Patients suffering from depression, anxiety and substance use disorders often search for years to find treatment. Studies have shown that during this time gap, patients’ symptoms worsen, increasing their risk for other chronic illnesses, shortened lifespan and poor quality of life. Mayo Clinic statistical geneticist Joanna Biernacka, Ph.D. and her colleagues are working to […]

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Tags: anxiety, biobank, Center for Individualized Medicine, depression, genetic testing, genetics, Joanna Biernacka, Mark Frye, psychiatry, substance abuse disorder


March 23, 2020

Collaboration brings innovative regenerative therapies to babies with rare heart defect

By Jennifer Schutz Jennifer Schutz

A collaboration bringing together regional centers and advocacy groups to accelerate innovation and discovery is expanding, bringing clinical trials and expertise to more patients with Hypoplastic Left Heart Syndrome (HLHS) across the country. Led by Mayo Clinic’s Todd and Karen Wanek Family Program for HLHS, the collaboration began in 2017 and now has 10 members. Nine […]

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Tags: Center for Regenerative Medicine, clinical trials, congenital heart disease, HLHS, hypoplastic left heart syndrome, pediatric cardiology, Tim Nelson


March 20, 2020

Mayo Researchers Develop Unique Tool, Lab to Study Vaping

By Advancing the Science contributor Advancing the Science contributor

Jon Ebbert, M.D., is sympathetic to the plight of the patients he sees who are struggling with addiction. “I saw a lot of addiction growing up,” he tells Rochester Magazine’s Steve Lange. “I know the damage it can do.” Dr. Ebbert, a Community Internal Medicine physician and researcher in Mayo Clinic’s Nicotine Dependence Center, also understands why […]

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Tags: Alexandra Ward, COVID-19, Jon Ebbert, lung disease, medical research, Nicotine Dependence Center, vaping


March 17, 2020

Regenerating missing bacteria for healthier lungs

By Jennifer Schutz Jennifer Schutz

Connection to COVID-19 People with COPD are at a greater risk of contracting COVID-19, and likely to experience much worse cases than people with healthy lungs. To help alleviate concerns, the COPD Foundation has set up a continuous blog with expert answers to questions related to COPD. In addition, the Centers for Disease Control and […]

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Tags: basic science, Center for Regenerative Medicine, COPD, COVID-19, discovery research, lung disease, Regenerative Medicine Minnesota, Veena Taneja


March 12, 2020

How a childhood goal of advocating for the sick led to medical school and beyond

By Advancing the Science contributor Advancing the Science contributor

Unrealistic. Selfish. Impossible. The words were lobbed at Waleed Gibreel, M.B.B.S., who has lived in the margins of two powerful forces that shaped him — his dream of becoming a top-flight surgeon and his reality of growing up in war-torn Sudan. “I knew as a child that my ultimate goal was to be a doctor, no […]

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Tags: Abdalla Zarroug, diversity, Mayo Clinic School of Graduate Medical Education, Michael Sarr, pediatric surgery, plastic surgery, research, research education, surgery, team science, Waleed Gibreel


March 11, 2020

Virus beware: cells can defend themselves

By Sara Tiner Sara Tiner

According to a new paper in Nature Communications, a protein known to help cells defend against infection also helps their mitochondria. The protein, one in a group called myxovirus-resistance (Mx) protein, helps cells without calling in white blood cells.  But now, the researchers report it also helps cells by preventing a virus from hijacking mitochondria. […]

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Tags: biomedical research, Hong Cao, infection, Mark McNiven, mitochondria


March 10, 2020

Patient’s premature aging symptoms tied to shorter DNA strands

By Colette Gallagher Colette Gallagher

At only 27-years-old, Morgan Cook recalls the days when she had an abundant amount of energy. “I would lift weights. I would do cardio. I would – you name it, I would do it. I was a lot more active,” says Cook. “I felt like I was able to do more things with friends. I […]

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Tags: Center for Individualized Medicine, DNA, genetic counseling, genetic testing, genetics, Mrinal Patnaik, rare disease, short telomere syndrome


March 6, 2020

Off the shelf vessels: A regenerative approach for coronary artery bypass

By Jennifer Schutz Jennifer Schutz

Growing blood vessels in a lab for human use may sound like a futuristic dream. However, Mayo Clinic researchers are seeking to do just that to advance a regenerative approach to coronary bypass graft surgery. Through a Regenerative Medicine Minnesota grant, a Mayo research team is developing tissue that could grow into a blood vessel […]

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Tags: biomedical engineering, blood vessels, Center for Regenerative Medicine, coronary artery disease, heart disease, Leigh Griffiths, Regenerative Medicine Minnesota, tissue engineering


March 2, 2020

Stem cells in space: A new frontier in regenerative medicine training

By Jennifer Schutz Jennifer Schutz

A Mayo Clinic graduate student is looking to the stars as a new way to advance regenerative therapies for cancer. Rawan Al-Kharboosh, a Ph.D. candidate at Mayo Clinic’s Florida campus, is investigating how stromal vascular fraction stem (SVF) cells react in microgravity and if that may be applied to fight the most deadly type of […]

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Tags: brain cancer, Center for Regenerative Medicine, Rawan Al-Kharboosh, regenerative medicine, stem cells


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