republished
January 31, 2023
Training scientists to rebuild health
By Advancing the Science contributor 
Experts predict that regenerative medicine will transform clinical practice. A conservative estimate is that 20% of future medical and surgical solutions will involve regenerative solutions. Regenerative medicine shifts the focus of medicine from fighting disease to rebuilding health. Regenerative medicine could improve human health span — the number of disease-free years — so a person’s […]
Tags: Andre Terzic, Armin Garmany, Center for Regenerative Medicine, Douglas Brownfield, Isobel Scarisbrick, Mayo Clinic Graduate School of Biomedical Sciences, medical research education, Nathaniel Blackwell, research education, Shan Gao, Stijn De Langhe
January 12, 2023
Studies show resiliency training may help kids’ well-being, decision-making skills, more
By Advancing the Science contributor
Mayo Clinic students and researchers are studying whether resiliency training can help children and adults live healthier, more productive lives.
Tags: anxiety, Catherine (Kit) Knier, Center for Clinical and Translational Science, Chris Pierret, depression, education, health equity, Lisa Schimmenti, Mayo Clinic Graduate School of Biomedical Sciences, medical research education, Medical Scientist Training Program, mental health
November 24, 2022
The future will be personalized: Accelerating microbiome research
By Advancing the Science contributor
We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings to […]
Tags: arthritis, C. diff, cancer, Center for Individualized Medicine, colitis, colorectal cancer, diabetes, endometrial cancer, Francis Farraye, gastroenterology, gut health, gynecology
November 18, 2022
CDC releases updated guideline for prescribing opioids for pain
On Nov. 4, the Centers for Disease Control and Prevention (CDC) released updated and expanded recommendations for clinicians providing pain care for adult outpatients with short- and long-term pain. These clinical recommendations, published in the CDC Clinical Practice Guideline for Prescribing Opioids for Pain, will help clinicians work with their patients to ensure the safest and […]
Tags: Center for the Science of Health Care Delivery, Centers for Disease Control and Prevention, Elizabeth Habermann, Halena Gazelka, opioids, pain management, practice improvement
November 17, 2022
Focus on community practice: Real-world research fuels better outcomes
By Advancing the Science contributor
It’s a Catch-22. You can’t improve community practice without evidence-based research, but it’s challenging to incorporate research into a busy primary care practice. And there’s a paucity of researchers devoted to primary care. “We’re busy seeing patients and trying to deliver the best care possible. It’s hard to find time to pause, step back and […]
Tags: Center for Clinical and Translational Science, Center for Health Equity and Community Engagement Research, community engagement, emergency medicine, geriatrics, health disparities, multiple chronic conditions, palliative care, pragmatic trials, Prathibha Varkey, primary care, Rozalina McCoy
October 11, 2022
Meet Surbhi Shah, M.B.B.S., M.D. – Driven to learn, incorporating learning to improve care
By Advancing the Science contributor
Surbhi Shah, M.B.B.S., M.D., is a hematologist at Mayo Clinic in Arizona., whose focus is on treating patients with non-cancerous blood disorders. In addition to her clinical duties, Dr. Shah dedicates time both to learning, and to sharing what she learns – through teaching, mentoring, presentation and publication. To expand her own understanding and increase Mayo’s […]
Tags: anticoagulant, blood disease, Center for the Science of Health Care Delivery, clinical research, Fadi Shamoun, hematology, hemophilia, Jennifer Ridgeway, Kern Health Care Delivery Scholars, learning health system, medical innovation, mentorship
September 27, 2022
Physician-scientist investigates dual CAR-T cell therapy for multiple myeloma cancer
By Susan Murphy
Leo Sakemura, M.D., Ph.D., a physician-scientist in Mayo Clinic’s Division of Hematology, is working to advance immunotherapy efficacy in multiple myeloma by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment. Dr. Sakemura’s previous […]
Tags: cancer genomics, cancer research, CAR-T cell therapy, Center for Individualized Medicine, hematology, immunotherapy, Leo Sakemura, metabolomics, multiple myeloma
September 26, 2022
Meet Khushboo Gala, M.B.B.S. — Finding fulfillment in helping others
By Advancing the Science contributor
Khushboo S. Gala, M.B.B.S. is a gastroenterology fellow in the Mayo Clinic School of Graduate Medical Education. She cares for patients and conducts clinical research at Mayo Clinic in Rochester, Minnesota. Dr. Gala recently became a Kern Health Care Delivery Scholar, commencing a mentored training and research program within the Mayo Clinic Robert D. and […]
Tags: Andres Acosta, Center for the Science of Health Care Delivery, Juan Brito Campana, Kern Health Care Delivery Scholars, Khushboo Gala, Mayo Clinic School of Graduate Medical Education, obesity, Victor Montori
September 22, 2022
A preclinical step toward treating chronic dry mouth
Mayo Clinic researchers replicated chronic dry mouth from radiation damage in preclinical models, laying the foundation for stem cell research to regenerate salivary tissue after cancer. This discovery uses targeted X-radiation to mimic human injury and establish a lab model for testing cellular therapies for dry mouth. The study is published in Radiation Research. “The […]
Tags: basic science, Center for Regenerative Medicine, discovery research, dry mouth, head and neck cancer, Jeffrey Janus, medical research, Nagarajan Kannan, otolaryngology, quality of life, radiation therapy, salivary glands
September 15, 2022
Meet Gustavo Cortes Puentes, M.D. — Compassionate Clinician Scientist
By Advancing the Science contributor
Gustavo Cortes Puentes, M.D. (@DrivingPressure), is a pulmonary and critical care specialist at Mayo Clinic in Rochester, Minnesota. Originally from Colombia, he came to Mayo by way of an internal medical residency with the University of Minnesota Medical School in Minneapolis, following a research scholar appointment during which he studied pulmonary mechanics and acute respiratory […]
Tags: Caroline Davidge-Pitts, Cassie Kennedy, Center for Health Equity and Community Engagement Research, Center for the Science of Health Care Delivery, Cesar Gonzalez, diversity, Gustavo Cortes Puentes, health disparities, Kaiser Lim, Kern Health Care Delivery Scholars, pulmonary and critical care medicine, Sean Phelan