Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

republished

September 28, 2021

An inside look at the state-of-the-art supports enabling invention

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Throughout Mayo Clinic, innovation is the thread that weaves through countless initiatives aimed at improving patient care. While Mayo’s most cutting-edge discoveries are often widely known, the vast majority of innovative endeavors occur behind the scenes. One of the more low-profile assets in Mayo Clinic Laboratories’ innovation arsenal is the media kitchen, where specialized media […]

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Tags: biomedical engineering, Mayo Clinic Laboratories


September 27, 2021

A robotic GPS for targeting, delivering regenerative biotherapies

By Susan Buckles Susan Buckles (@susanbuckles)

A remote-controlled bronchoscope that acts like a GPS system hunts down hard to find lung masses and accurately biopsies them, according to a Mayo Clinic collaborative study. This multisite research, which is published in Annals of Thoracic Surgery, lays the foundation for precisely finding early stage cancer and targeting it with regenerative biotherapeutics needed to […]

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Tags: biotherapeutics, Center for Regenerative Medicine, early stage lung cancer, Janani Reisenauer, Julie Allickson, robotic bronchoscope


September 20, 2021

A regenerative refresh to cosmetic procedures

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has launched a regenerative cosmetic service for patients aimed at resetting the body’s clock to a time of more youthful function and appearance. The Multidisciplinary Cosmetic Center at Mayo Clinic in Arizona pairs general and facial plastic surgery with dermatologists, gynecologists, vascular surgery, urologists and aestheticists to deliver services grounded in scientific evidence […]

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Tags: Brittany Howard, Center for Regenerative Medicine, fat grafting, laser therapy, Michael Hinni, Multidisciolinary Cosmetic Center, platelet rich plasma, rhinoplasty


September 16, 2021

A fountain of youth for aging muscles

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine could hold the keys to rejuvenating older muscles, and research supporting that will be featured at the Mayo Clinic Symposium on Regenerative Medicine and Surgery. Preclinical research by Helen Blau, Ph.D., Stanford University School of Medicine, discovered a protein that triggers muscle loss and a way to block it to restore youthful muscle […]

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Tags: aging, Center for Regenerative Medicine, Helen Blau, Julie Allickson, Mayo Clinic Symposium on Regenerative Medicine & Surgery, Richard Hayden, sarcopenia


September 9, 2021

Q&A with outgoing director, Center for Regenerative Medicine

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine pioneer Andre Terzic, M.D., Ph.D., was named inaugural director of Mayo Clinic’s Center for Regenerative Medicine on Jan. 4, 2011. Dr. Terzic built out regenerative medicine across Research, Practice and Education, integrating this emerging field into all medical and surgical specialties, laboratory medicine and radiology. Under his leadership, Mayo Clinic built a reputation […]

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Tags: Andre Terzic, Center for Regenerative Medicine


September 8, 2021

Genetic variants influence migraine treatment response, according to new Mayo study

By Susan Murphy Susan Murphy (@susanmurphy)

Migraines affect nearly 40 million people in the U.S. Yet pinpointing an effective prophylactic medication ― the most commonly prescribed drugs for people diagnosed with migraines ― remains a long and complex process. Patients often cycle through medications for weeks or months until achieving a therapeutic response.  Now after years of slow progress in migraine therapies […]

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Tags: Center for Individualized Medicine, Fred Cutrer, genetics, migraine, neurology, personalized medicine, pharmacogenomics, Richard Weinshilboum


September 2, 2021

Understanding the inner workings of CAR-T therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: CAR-T, Center for Individualized Medicine, Center for Regenerative Medicine, chimeric antigen receptor therapy, clinical research, clinical trials, hematology, immunotherapy, Kah Whye Peng, Reona Sakemura, Saad Kenderian, Stephen Russell


September 1, 2021

Uterine microbe found to have disease-causing behavior in endometrial cancer

By Susan Murphy Susan Murphy (@susanmurphy)

A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study.  “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is stimulated […]

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Tags: Center for Individualized Medicine, endometrial cancer, Marina Walther-Antonio, microbiome, women's health


August 30, 2021

Regenerating the rotator cuff

By Susan Buckles Susan Buckles (@susanbuckles)

Preclinical studies discovered a cell-free bioactive material developed at Mayo Clinic triggered healing of one of the most common shoulder injuries. This Mayo Clinic research, published in Biomaterials, documented that purified exosome product —  also known as PEP — promoted repair of rotator cuff injuries faster and more effectively than surgery alone. The rotator cuff […]

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Tags: Center for Regenerative Medicine, Chungfeng Zhao, extracellular vesicles


August 25, 2021

Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]

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Tags: Center for Individualized Medicine, DNA, gastroenterology, genomics, gut health, IBS, irritable bowel syndrome, microbiome, Purna Kashyap


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