Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Progress Updates

September 21, 2022

Maintaining quality care for patients with ALS — Lessons from the pandemic

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Susan Barber Lindquist The efficiency and effectiveness of telemedicine exploded during the COVID-19 pandemic. For patients with Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis or ALS, telemedicine always has been an important piece of their medical care. A recent study in Neurology by Mayo Clinic researchers offers one more proof point. Tests […]

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Tags: ALS, amyotrophic lateral sclerosis, clinical trials, COVID-19, Lou Gehrig's disease, Nathan Staff, neurology, remote patient monitoring, telehealth, telemedicine


August 2, 2022

Addressing the challenges of chimeric antigen receptor-T cell therapy

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T […]

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Tags: cancer therapy, CAR-T cell therapy, Center for Regenerative Medicine, Hong Qin, regenerative immunotherapy, Saad Kenderian


June 30, 2022

Lupus rates increasing, communities of color especially vulnerable

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

New research led by Mayo Clinic shows that more people are being diagnosed with lupus than in the past, while risks of severity and death remain the same. The study is published in BMJ Annals of the Rheumatologic Diseases. Lupus is a chronic autoimmune disorder that causes inflammation and pain throughout the body. Most common in […]

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Tags: Alain Sanchez Rodriguez, Ali Duarte Garcia, autoimmune disorder, Center for the Science of Health Care Delivery, Centers for Disease Control and Prevention, Cindy Crowson, epidemiology, health disparities, Jesse Dabit, Kern Health Care Delivery Scholars, lupus, rheumatology


June 15, 2022

Research News Roundup — May 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In May, researchers from Mayo Clinic reported gains in understanding of the benefit of AI-enabled ECGs, including from wearable devices. They made strides towards more effective treatment of non-Hodgkin lymphoma and nonmetastatic gastroesophageal cancer. And in news many people can use, investigators report on the results of a survey linked to the Mayo Clinic Diet. […]

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Tags: AFib, artificial intelligence, atrial fibrillation, CAR-T cell therapy, Center for the Science of Health Care Delivery, clinical trials, cognitive impairment, EKG, electrocardiogram, esophageal cancer, gastric cancer, gastroesophageal cancer


May 31, 2022

Mayo research using DNA to catch cancer, other medical conditions earlier

By Adam Harringa Adam Harringa (@harringaadam)

What would happen if a certain percentage of serious medical conditions, including cancer diagnoses, were found significantly earlier by studying the entire genome of patients’ DNA? How would their quality of life improve, and how many fewer cancer deaths would there be each year? That’s what a group of Mayo Clinic scientists and clinicians aim […]

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Tags: Bijan Borah, breast cancer, Center for Individualized Medicine, Center for the Science of Health Care Delivery, Centers for Disease Control and Prevention, DNA, genome, genomics, health disparities, hereditary cancer, hereditary diseases, hypercholesterolemia


March 30, 2022

Young girl with rare disease gets life-changing diagnosis and targeted therapy at Mayo Clinic

By Susan Murphy Susan Murphy (@susanmurphy)

Araeya Sell, 13, has spent much of her childhood visiting her health care team and in the hospital. She has endured countless blood draws, scans, procedures and a surgery ― all in the search for answers to her complex symptoms.  “It started in kindergarten when Araeya just kept getting bladder infections,” says her mother, Nicole […]

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Tags: Center for Individualized Medicine, Filippo Pinto e Vairo, genetic testing, genetics, genomics, individualized medicine, Konstantinos Lazaridis, rare disease, William Faubion Jr.


February 10, 2022

Advanced Care at Home — Evidence-based practice transformation                                        

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Before the pandemic, Mayo Clinic was exploring ways to help patients get home sooner or avoid hospital admission all together. This work has continued, and one of Mayo’s key initiatives in this arena is the Advanced Care at Home program, currently available in Mayo Clinic Health System in Eau Claire, Wisconsin; and at Mayo Clinic […]

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Tags: Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, clinical trials, Elizabeth Habermann, Mayo Clinic Cancer Center, Mayo Clinic Health System, Mayo Clinic Platform, Michael Maniaci, practice improvement, pragmatic trials, Sean Dowdy, Xiaoxi Yao


February 3, 2022

Instead of health care, how about “well care”?

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Recent Mayo Clinic research showed that it is possible to electronically connect community health and wellness program information with people’s medical records in a reliable and secure manner. The combined data can help patients and their doctors identify promising programs that may help patients reach their health and wellness goals. The linkage can also provide […]

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Tags: Aaron Leppin, Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, community engagement, general internal medicine, health equity, learning health system, Paul Takahashi, population health, quality improvement, Rochester Epidemiology Project, Sarah Redmond


January 20, 2022

Modeling takes a whole new twist with omicron

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Since shortly after COVID-19 started popping up in the U.S., Mayo Clinic’s Predictive Analytics Task Force has been tracking it. A collaboration between Mayo Clinic Quality and the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, the task force’s primary responsibility is to build and maintain a […]

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Tags: biostatistics, Center for the Science of Health Care Delivery, COVID-19, Curt Storlie, data science, epidemiology, Katherine Noe, quality improvement, Shannon Dunlay


January 6, 2022

Big data helps in understanding asthma biologic use, outcomes

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

According to the Centers for Disease Control and Prevention, about 25 million Americans have asthma, and that number is increasing every year. In the last 10 years, a number of new medications have become available. Collectively referred to as ‘biologics,’ these therapies are made to target very specific parts of the body and its immune […]

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Tags: asthma, big data, Che Ngufor, inflammation, Jacob Maddux, Matthew Rank, Molly Jeffery, Nilay Shah, OptumLabs


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