Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

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February 12, 2021 · Leave a Comment

Body fat investigation provides insights for ‘obesity paradox’

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The Obesity Paradox Excerpted from a 2009 Mayo Clinic Proceedings article, The Obesity Paradox: Perception vs Knowledge. “Data from several epidemiological studies, including the Framingham Heart Study, have found a positive relationship between obesity and mortality, in particular cardiovascular mortality. However, several cross-sectional, retrospective database studies … have found an inverse correlation between body mass […]

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Tags: animal model, basic science, biomedical research, discovery research, gastroenterology, molecular biology, obesity, pancreatitis, Vijay Singh


February 2, 2021 · Leave a Comment

Diabetes treatment disparities widespread, room for improvement

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

More than 34 million people in the U.S. have diabetes, reports the Centers for Disease Control and Prevention. Of these, the vast majority have type 2, or a reduced ability of their bodies to effectively process sugar in foods into energy for life. Most people with type 2 diabetes have multiple considerations – including heart […]

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Tags: Centers for Disease Control and Prevention, diabetes, health care value, health disparities, health equity, heart disease, hypoglycemia, kidney disease, medication management, OptumLabs, pharmacy, Rozalina McCoy


January 28, 2021 · Leave a Comment

Regenerating the larynx: A second chance at speech

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is leveraging advances in regenerative medicine to restore function for people whose lives have been drastically changed by a laryngectomy — surgery to remove the voice box. People without a voice box can neither speak with their natural voices nor breathe through their noses. Simple pleasures like smelling a bouquet of flowers or […]

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Tags: 3D printing, cancer, Center for Regenerative Medicine, clinical research, clinical trials, David Lott, laryngeal cancer, laryngectomy, larynx transplant, Richard Hayden, stem cell research, stem cells


January 27, 2021 · Leave a Comment

Mitochondria vs. Alzheimer’s

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Targeting mitochondria is a promising therapeutic strategy, study shows “Mitochondria are the powerhouses of the cell.” Many a young science student has heard that truism. “Mitochondria are extremely important because they ensure that we have energy supply for cells to conduct functions,” says Mayo Clinic researcher Eugenia Trushina, Ph.D. “Otherwise, we would all be dead […]

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Tags: Alzheimer's disease, animal model, basic science, clinical trials, discovery research, drug discovery, Eugenia Trushina, Kogod Center on Aging, Minnesota Partnership, mitochondria, National Cancer Institute, National Institutes of Health


January 25, 2021 · Leave a Comment

Mayo Clinic Research in the news — 1/25/2021

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

From acupuncture, breast cancer, diabetes, euthyroid … all the way to Zika, Mayo Clinic research and experts are featured in the news. Also find COVID-19 observations, advice and findings. Acupuncture Cancer Pain Results – Florida, Minnesota, Arizona HealthCMI, 1/22/2021 Florida, Minnesota, and Arizona Mayo Clinic researchers find systematic review evidence indicating that acupuncture is safe […]

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Tags: acupuncture, acute flaccid myelitis, ADHD, Alzheimer's disease, amyloidosis, artificial intelligence, biomarkers, breast cancer, Brent Bauer, cancer, cancer genomics, CBD


January 11, 2021 · Leave a Comment

Mayo Clinic Research in the news — 1/11/2021

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

In the news you’ll find Mayo Clinic research and faculty cited on a variety of topics including women’s health, patient consent, migraine, palliative care and of course COVID-19. Radiologists assert new data consent agreements are needed before patient trust is gone Health Imaging, 1/8/2021 Patient health data has become a valuable commodity, helping researchers develop […]

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Tags: Alzheimer's disease, Amy Kotsenas, artificial intelligence, Barrett's esophagus, consent, COVID-19, data science, esophageal cancer, Frank Porreca, gene mutation, genetic testing, Hilary DuBrock


January 6, 2021 · Leave a Comment

Diverse ways regenerative medicine is advancing health care

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative medicine has contributed to patient care in 2020 more than ever before, bolstered by synergies in research, practice and education. Mayo Clinic’s Center for Regenerative Medicine is at the forefront of a biotherapy revolution in which health care advances from treating disease to restoring health. “The centrality of the body to regenerate itself is […]

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Tags: 3D printing, Andre Terzic, artificial intelligence, Atta Behfar, autoimmune disorder, biomedical engineering, CAR T-cell therapy, Center for Regenerative Medicine, clinical research, clinical trials, data science, fetal surgery


January 5, 2021 · Leave a Comment

Looking back on 2020: A successful year of research at Mayo Clinic in Florida

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

At Mayo Clinic, Research and Education provide the basis for all we are able to do for patients today. Furthermore, they enable practice transformation as we seek to meet future patient needs. From new capabilities in cell therapy and immunotherapy, to advances in neurodegenerative diseases and studies of the virus that causes COVID-19, research at Mayo Clinic continued […]

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Tags: Alzheimer's disease, Ben Pollock, biomanufacturing, biomarkers, biostatistics, brain, cancer, CAR-T, carbon ion therapy, Center for Regenerative Medicine, chemotherapy, clinical research


November 19, 2020 · Leave a Comment

Breast cancer accurately staged with fewer lymph nodes

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

When a person is diagnosed with breast cancer, surgery can be their first treatment. Other times, their clinician will prescribe chemotherapy before surgery, called neoadjuvant chemotherapy. In both cases, for patients with clinically negative nodes at presentation, surgeons will determine at the time of surgery how far the cancer has spread by removing and examining […]

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Tags: breast cancer, Brittany Murphy, cancer research, Center for the Science of Health Care Delivery, chemotherapy, Judy Boughey, lymphatic system, lymphedema, Mayo Clinic College of Medicine and Science, oncology, residency program


November 9, 2020 · Leave a Comment

Mayo Clinic Research in the news — 11/9/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

As SARS-CoV-2 spreads throughout the world, COVID-19 has become the subject of almost every conversation. Not surprisingly, the media are actively following developments in research on symptoms, testing, treatment and vaccines. In addition to some of these stories, you’ll find Mayo Clinic research and researchers highlighted across a wide range of topics. We are also […]

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Tags: ALS, Alzheimer's disease, amyotrophic lateral sclerosis, animal model, ASTRO, bone disease, cancer screening, cardiovascular medicine, clinical research, colorectal cancer, COVID-19, David Ahlquist


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