Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Progress Updates

July 10, 2018

Using biological particles from milk to target liver cancer

By Kate Ledger k8ledger

Among cancers, liver tumors have been particularly hard for doctors to treat. The cancer cells tend to be hardy from the beginning and even undergo changes that make them more resistant to chemotherapies. What’s clear is that an effective treatment needs to reach the cancer cells, and not affect or damage the normal liver. The […]

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Tags: basic science, Center for Regenerative Medicine, liver cancer, Mayo Clinic Cancer Center, Tushar Patel


June 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Brudos Ferrara nicoleferrara

Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, M.D., M.B., B.Ch., a specialist […]

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Tags: basic science, Center for Individualized Medicine, DNA, Ferga Gleeson, gastroenterology, individualized medicine, pancreatic cancer, precision medicine


June 13, 2018

Following grant renewal, CCaTS abuzz with activity

By Caitlin Doran caityrosey

In October 2017, the National Institutes of Health (NIH) renewed Mayo Clinic’s Clinical and Translational Science Award from the National Center for Advancing Translational Sciences—an award totaling $48.8 million over five years. This renewal allows Mayo Clinic to continue pursuing its long-term goals in clinical and translational science, while also setting new short term objectives. […]

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Tags: Adil Bharucha, Amanda Leightner, Andrew Badley, Center for Clinical and Translational Science, clinical trials, David Warner, education, Stephen Ekker, Sundeep Khosla, zebrafish


June 5, 2018

Research News Roundup-May 2018

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. News flash about hot flashes: They can last longer than you think Mayo Clinic study finds women are experiencing hot flashes, night […]

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Tags: All of Us, atrial fibrillation, Center for Individualized Medicine, Center for the Science of Health Care Delivery, Eva Galanis, Gianrico Farrugia, HLHS, hypoplastic left heart syndrome, Judy Boughey, lung cancer, Matthew Goetz, Mayo Clinic Cancer Center


May 24, 2018

Mayo’s RIGHT 10K – moving pharmacogenomics into everyday clinical practice

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog on March 20, 2018. By Sharon Rosen After nearly half a century of research, Mayo Clinic is a leader in moving pharmacogenomics into clinical practice. This year pharmacogenomics test results for 10,000 Mayo Clinic patients, all participants in the RIGHT 10K study, are being added […]

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Tags: biobank, Center for Individualized Medicine, DNA testing, genetics, Paul Takahashi, pharmacogenomics, Richard Weinshilboum


May 8, 2018

Doctor, are you feeling okay?

By Elizabeth Zimmermann elizabethzimmermann

For physicians, the practice of medicine comes with a cost beyond medical school bills. In many cases, our doctors pay in health and wellness. And Americans pays, too. Mayo Clinic researchers and collaborators have estimated that the annual cost of physicians leaving the medical profession or making an error due to burnout could be $3.4 […]

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Tags: Colin West, Lotte Dyrbye, physician burnout


May 2, 2018

Research News Roundup-April 2018

By Elizabeth Zimmermann elizabethzimmermann

Each month, we publish Mayo Clinic’s Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month’s Roundup includes some exciting news from Mayo Clinic Health System, and we expect we’ll be […]

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Tags: clinical trials, integrative medicine, Mayo Clinic Cancer Center, Mayo Clinic Health System, Mayo Clinic Proceedings, opioids, Research News Roundup, Timothy Nelson


March 27, 2018

Regenerative sports medicine

By Jennifer Schutz jenniferschutz

Stem cells are, perhaps, the most widely known component of regenerative therapy, but they are not the only one, and each has its own application: Stem cells can be used to grow new tissue of any type in the body if injected at the site of injured or damaged tissues and activated. Growth factors is a term for […]

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Tags: Center for Regenerative Medicine, Jonathan Finnoff, regenerative medicine, sports medicine, stem cells


March 13, 2018

Regenerative medicine therapies program at Mayo Clinic in Florida

By Jennifer Schutz jenniferschutz

Shane Shapiro, M.D., is dedicated to advancing the science of orthopedics and regenerative medicine through research. He is assistant professor of orthopedic surgery and program director for the Regenerative Medicine Therapeutic Suites, Mayo Center for Regenerative Medicine. In the video below, Dr. Shapiro discusses the results of his randomized controlled trial of bone marrow aspiration […]

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Tags: Center for Regenerative Medicine, clinical trials, orthopedics, osteoarthritis, Shane Shapiro, stem cells


February 20, 2018

Researching stem cell therapy for lung transplant patients

By Jennifer Schutz jenniferschutz

In a recent study in Stem Cells Translational Medicine, a team of researchers at Mayo Clinic looked at the safety and feasibility of using stem cells to treat a condition that can devastate lung transplant patients. The disease itself is called bronchiolitis obliterans syndrome, or BOS, and involves inflammation and scarring in the smallest branches of […]

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Tags: Center for Regenerative Medicine, Cesar Kellar, clinical trials, regenerative medicine, stem cells, transplant


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