Advancing the Science

Mayo Clinic Medical Science Blog

Progress Updates

June 27th, 2017

Personalized care for aggressive breast cancers: 4 steps forward from the BEAUTY study

By susanbuckles susanbuckles

Article by Sharon Rosen Chemotherapy substantially reduces the chance that certain types of breast cancer will return or spread to other parts of the body and improves survival. Chemotherapy before surgery is a standard approach to treat women with aggressive breast cancer. However, chemotherapy does not shrink tumors in all women. Mayo Clinic researchers are […]

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Tags: Agressive breast cancer, BEAUTY study, breast cancer research, breast cancer treatment, Center for Individualized Medicine, Dr. Judy Boughey, Dr. Matthew Goetz, Mayo Clinic Cancer Center, Xeongrafts


June 1st, 2017

Rochester Epidemiology Project: Taking a bite out of poor health

By Elizabeth Zimmermann Young elizabethzimmermann

The Rochester Epidemiology Project has added dental records to its database of linked medical records, making it more valuable as a medical research resource. The Rochester Epidemiology Project is a collaboration of medical and dental care providers in Minnesota and Wisconsin. With patient agreement, the organizations link medical, dental, surgical procedures, prescriptions, and other health […]

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Tags: Alan Carr, Daniel DeSimone, dental, dentist, Kern Center, Mayo Clinic Proceedings, Olm, Olmsted Medical Center, oral health, population health, public health, REP


May 25th, 2017

Her Way Back

By Elizabeth Zimmermann Young elizabethzimmermann

HER WAY BACK North Dakota woman on leading edge of epilepsy research with implanted device For the 50 million children and adults worldwide who live with epilepsy, the brain’s electrical circuitry shorts out spontaneously. As many as one-third of patients, 1 million in the U.S. alone, find no relief with existing medications and must explore […]

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Tags: clinical trial, epilepsy, Gregory Worrell, medical device, medical research, neurology, North Dakota, research, seizure, Sheri Finstad


February 16th, 2017

Yale and Mayo Clinic collaborate to further regulatory science

By Adam Harringa harringaadam

Author Kevin Lin, Yale Daily News staff Funded by a United States Food and Drug Administration grant of up to $6.7 million over two years, Yale and Mayo Clinic are establishing a Center of Excellence in Regulatory Science and Innovation to advance regulatory science by developing tools to measure the safety and efficacy of FDA-regulated […]

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Tags: cersi, health care delivery, regulatory science, yale


January 31st, 2017

Contrast Dye in Kidney Disease Patients: Reducing the Risk of an Important Diagnostic Tool

By Elizabeth Zimmermann Young elizabethzimmermann

Building the evidence base for best practice Medical research has resulted in many amazing diagnostic and treatment methods, tools and drugs. Today a physician can look inside her patient’s body through the aid of radiation and iodine-based dyes in the blood stream – both of which could be deadly in another time or place. This […]

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Tags: Clinical Imaging, contrast dye, Florida, kidney disease, nephropathy


January 26th, 2017

National health research treasure marks 50 years

By Elizabeth Zimmermann Young elizabethzimmermann

In 2002, Giancarlo Logroscino, M.D., Ph.D., then a research scientist at the Sergievsky Center at Columbia University in New York City, published the only paper on the long-term prognosis of status epilepticus (SE) along with research collaborators from Columbia and Mayo Clinic. They established for the first time,  in a rigorous investigation of SE in […]

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Tags: Dr. Giancarlo Logroscino, Dr. Jenny St. Sauver, Dr. Walter Rocca, Dr. Wenjun Zhong, Mayo Clinic Alumni Magazine, population health, REP, Rochester Epidemiology Project, Science of health care delivery


January 9th, 2017

Single Allele Mutation Heightens Risk of Early-Onset Parkinson’s

By Bob Nellis bobnellis

A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic’s campus in Florida, found that a mutation in only one allele of a Parkinson’s gene, known as PINK1, increases the risk of early-onset disease. The finding, published recently in the journal Brain, addresses a longstanding debate about whether individuals need to […]

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Tags: Mayo Clinic research, neurology, neurosciences, Parkinson's, Wolfdieter Springer


December 15th, 2016

Combination therapy improves survival in adults with glioma

By Nicole Brudos Ferrara nicoleferrara

Radiation plus three-drug combo boosts progression-free survival and overall survival. Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than did patients who received radiation therapy alone. These are the results of […]

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Tags: brain cancer, cancer reseach, glioma, Jan Buckner, lomustine, PCV, procarbazine, radiation therapy, vincristine


December 13th, 2016

Nipple-sparing mastectomy may be a good option

By Elizabeth Zimmermann Young elizabethzimmermann

Technique offers a safe way to reduce breast cancer risk in carriers of the BRCA mutation. Mastectomies that preserve the nipple and surrounding skin prevent breast cancer as effectively as do more-invasive surgeries for women with a genetic mutation called BRCA, a multi-institution study led by Mayo Clinic Cancer Center found. The study findings were presented […]

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Tags: BRCA, breast cancer, Forefront, James Jakub, mastectomy, Mayo Clinic Cancer Center, nipple-sparing


December 6th, 2016

New strategies could make laryngectomies a thing of the past

By Elizabeth Zimmermann Young elizabethzimmermann

About 60,000 Americans have had their larynx removed due to disease or trauma. These people are missing out on many of life’s little pleasures because the procedure’s resultant hole left them without a voice and created an opening directly into their lungs. A simple shower is dangerous as even the slightest amount of water in […]

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Tags: Arizona, Center for Regenerative Medicine, David Lott, laryngectomy, medical research, regenerative medicine, stem cells


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