Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘animal model’

April 4, 2022

Research News Roundup — March 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

March news reports are often focused on college basketball, daylight savings time and Mardi Gras. This year, Ukraine and the its people are top of mind for many, providing a sobering counterpoint. Behind the scenes, research has continued at Mayo Clinic, and several findings were released in March that help build the evidence and point […]

View full entry

Tags: aging, Alzheimer's disease, animal model, artificial intelligence, biomarkers, chemotherapy, collaboration, COVID-19, depression, discovery research, drug discovery, genomics


March 28, 2022

Regenerative Medicine Minnesota awards 5 research grants to Mayo Clinic

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative Medicine Minnesota, a statewide bipartisan initiative, has awarded five grants to Mayo Clinic investigators to advance new therapeutic options for osteoarthritis, liver disease, rotator cuff injuries and neurological birth defects. People in Minnesota and beyond struggle with chronic diseases such as heart disease, arthritis and diabetes, and standard care doesn’t always ease the symptoms. […]

View full entry

Tags: Aaron Krych, animal model, cartilage, cellular therapy, Center for Regenerative Medicine, Chunfeng Zhao, clinical trials, Jennifer Westendorf, liver failure, mesenchymal stem cells, minimally invasive procedure, molecular biology


March 2, 2022

Research News Roundup — January, February 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

At Mayo Clinic, researchers work across the spectrum of health care and disease, from basic discovery science to transformations in patient care. They translate early findings into therapeutic or preventive interventions via clinical research and innovative pilot projects. Mayo Clinic researchers publish thousands of articles in peer-reviewed journals each year. A fraction of those findings […]

View full entry

Tags: A. Noelle Larson, Andrew Bentall, animal model, anticoagulant, biomedical engineering, bone regeneration, cardiovascular disease, chemotherapy, cirrhosis, COVID-19, gastrointestinal cancer, health disparities


July 19, 2021

Mayo Clinic Research in the news — 7/19/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Mayo research and faculty expertise were cited on topics such as the health benefits of a pet, narcolepsy, the benefits of second opinions for patient outcomes, hiccups, COVID-19 modeling and a variety of other healthcare concerns. Star Tribune, Competing models at start of pandemic hurt public’s trust … Mayo leaders in spring 2020 reached out […]

View full entry

Tags: Abinash Virk, aging, Alzheimer's disease, Andrew Badley, Andrew Jagim, anemia, animal model, antiplatelet, anxiety, artificial intelligence, bioethics, biomedical ethics


June 21, 2021

Mayo Clinic Research in the news — 6/21/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Mayo Clinic research and faculty experts were in the news this week on managing life after COVID-19 and vaccine-related questions, as well as migraine, hiccups, the state of HIV research and more. Nervous about resuming activities? How to manage ‘COVID transition anxiety’  Star Tribune, 6/17/2021 We asked Reese Druckenmiller, a therapist with Mayo Clinic Health […]

View full entry

Tags: Andrew Badley, animal model, arthritis, artificial intelligence, Ashima Makol, breast cancer, cancer, cardiology, cost of care, COVID-19, David Dodick, David Nestler


June 17, 2021

Regenerative pipeline for spinal cord repair

By Sara Tiner Sara Tiner (@saratiner)

Mayo Clinic researchers are learning how stem cell therapy can treat neurodegenerative diseases. Mayo is among the first to study whether stem cell therapy might trigger healing for spinal cord injury. Research is ongoing in preclinical models, but it also has advanced from discovery science to early clinical trials. It’s a complex question, because different […]

View full entry

Tags: animal model, Ansh Goyal, Anthony Windebank, Bingkun Chen, Center for Regenerative Medicine, clinical trials, F. M. Moinuddin, medical research, mesenchymal stem cells, Mohamad Bydon, Mohammed Ali Alvi, spinal cord injury


June 14, 2021

Mayo Clinic Research in the news — 6/14/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Read on for news of the week that includes Mayo Clinic Research and research experts. Topics include a new Alzheimer’s medication, COVID-19, and various regenerative medicine innovations. US approves first new Alzheimer’s drug in 20 years  BBC, 6/8/2021 A controversial drug to treat Alzheimer’s disease has been approved by the Food and Drug Administration in […]

View full entry

Tags: aging, Alzheimer's disease, Andre Terzic, animal model, biomedical ethics, brain, BRCA1, breast cancer, cancer, Center for Regenerative Medicine, Cheryl Willman, concussion


February 12, 2021

Body fat investigation provides insights for ‘obesity paradox’

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The Obesity Paradox Excerpted from a 2009 Mayo Clinic Proceedings article, The Obesity Paradox: Perception vs Knowledge. “Data from several epidemiological studies, including the Framingham Heart Study, have found a positive relationship between obesity and mortality, in particular cardiovascular mortality. However, several cross-sectional, retrospective database studies … have found an inverse correlation between body mass […]

View full entry

Tags: animal model, basic science, biomedical research, discovery research, gastroenterology, molecular biology, obesity, pancreatitis, Vijay Singh, visceral fat


January 27, 2021

Mitochondria vs. Alzheimer’s

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Targeting mitochondria is a promising therapeutic strategy, study shows “Mitochondria are the powerhouses of the cell.” Many a young science student has heard that truism. “Mitochondria are extremely important because they ensure that we have energy supply for cells to conduct functions,” says Mayo Clinic researcher Eugenia Trushina, Ph.D. “Otherwise, we would all be dead […]

View full entry

Tags: Alzheimer's disease, animal model, basic science, clinical trials, discovery research, drug discovery, Eugenia Trushina, Kogod Center on Aging, Minnesota Partnership, mitochondria, National Cancer Institute, National Institutes of Health


December 1, 2020

Could regenerative medicine provide a new approach to diabetes care?

By Susan Buckles Susan Buckles (@susanbuckles)

November is National Diabetes Month, a time to reflect on new ways to manage a chronic condition that affects young and old. Mayo Clinic is applying a regenerative lens to advancing diabetes care beyond routine blood checks and standard insulin therapy. Quinn Peterson, Ph.D.; Aleksey Matveyenko, Ph.D.; and Alexander Revzin, Ph.D., are collaborating on a […]

View full entry

Tags: Aleksey Matveyenko, Alexander Revzin, animal model, cell replacement therapy, Center for Regenerative Medicine, Centers for Disease Control and Prevention, diabetes, Quinn Peterson, stem cells


Contact Us · Privacy Policy