Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘animal model’

February 12, 2021 · Leave a Comment

Body fat investigation provides insights for ‘obesity paradox’

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The Obesity Paradox Excerpted from a 2009 Mayo Clinic Proceedings article, The Obesity Paradox: Perception vs Knowledge. “Data from several epidemiological studies, including the Framingham Heart Study, have found a positive relationship between obesity and mortality, in particular cardiovascular mortality. However, several cross-sectional, retrospective database studies … have found an inverse correlation between body mass […]

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Tags: animal model, basic science, biomedical research, discovery research, gastroenterology, molecular biology, obesity, pancreatitis, Vijay Singh


January 27, 2021 · Leave a Comment

Mitochondria vs. Alzheimer’s

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Targeting mitochondria is a promising therapeutic strategy, study shows “Mitochondria are the powerhouses of the cell.” Many a young science student has heard that truism. “Mitochondria are extremely important because they ensure that we have energy supply for cells to conduct functions,” says Mayo Clinic researcher Eugenia Trushina, Ph.D. “Otherwise, we would all be dead […]

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Tags: Alzheimer's disease, animal model, basic science, clinical trials, discovery research, drug discovery, Eugenia Trushina, Kogod Center on Aging, Minnesota Partnership, mitochondria, National Cancer Institute, National Institutes of Health


December 1, 2020 · Leave a Comment

Could regenerative medicine provide a new approach to diabetes care?

By Susan Buckles Susan Buckles (@susanbuckles)

November is National Diabetes Month, a time to reflect on new ways to manage a chronic condition that affects young and old. Mayo Clinic is applying a regenerative lens to advancing diabetes care beyond routine blood checks and standard insulin therapy. Quinn Peterson, Ph.D.; Aleksey Matveyenko, Ph.D.; and Alexander Revzin, Ph.D., are collaborating on a […]

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Tags: Aleksey Matveyenko, Alexander Revzin, animal model, cell replacement therapy, Center for Regenerative Medicine, Centers for Disease Control and Prevention, diabetes, Quinn Peterson, stem cells


November 9, 2020 · Leave a Comment

Mayo Clinic Research in the news — 11/9/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

As SARS-CoV-2 spreads throughout the world, COVID-19 has become the subject of almost every conversation. Not surprisingly, the media are actively following developments in research on symptoms, testing, treatment and vaccines. In addition to some of these stories, you’ll find Mayo Clinic research and researchers highlighted across a wide range of topics. We are also […]

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Tags: ALS, Alzheimer's disease, amyotrophic lateral sclerosis, animal model, ASTRO, bone disease, cancer screening, cardiovascular medicine, clinical research, colorectal cancer, COVID-19, David Ahlquist


August 26, 2020 · Leave a Comment

Mayo Clinic Research in the news — 8/26/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Although it hasn’t even been a week, many news outlets have featured Mayo Clinic Research and our research experts in articles across a broad range of topics. In order not to overload – it really is shaping up to be an interesting week – we’ll save COVID-related news for another day. Read on to hear […]

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Tags: Allisa Song, Alzheimer's disease, animal model, Clifford Jack Jr., dogs, fibromyalgia, hypertension, liver disease, Mayo Clinic Alix School of Medicine, Mayo Clinic Proceedings, medical research education, menopause


August 6, 2020 · Leave a Comment

Calcium Signaling in Microglia: Implications for Brain Diseases?

By Sara Tiner Sara Tiner (@saratiner)

Calcium helps nerves and muscles “fire,” signaling cells to do something like contract a muscle or release a neurotransmitter in the brain. But in one type of brain cell, microglia, this calcium signaling seemed absent. Researchers have long wondered why microglia don’t seem to rely on calcium signaling and now, with a recent publication in […]

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Tags: animal model, Anthony Umpierre, basic science, calcium, cell signaling, discovery research, Gregory Worrell, Long-Jun Wu, neurology, neurosciences, Yanlu Ying


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