Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘antibacterial resistance’

May 18, 2022

Mayo patient with life-threatening multidrug-resistant infection treated with experimental phage therapy combined with surgery  

By Susan Murphy Susan Murphy (@susanmurphy)

Mark Pearce, 61, was facing a possible limb amputation, even death, when a multidrug-resistant bacterial infection within his prosthetic hip replacement device started raging in his bloodstream. With his fever soaring to more than 105 degrees, Mark was taken by ambulance, that day in spring of 2020, to Mayo Clinic Hospital in Rochester, Minnesota.  “My […]

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Tags: antibacterial resistance, bacteriophages, Center for Individualized Medicine, infection, phage


March 23, 2022

Nanopore sequencing method rapidly detects, identifies antibiotic-resistant microbes, Mayo Clinic research shows 

By Susan Murphy Susan Murphy (@susanmurphy)

A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections.  In response, a team of researchers from Mayo Clinic’s Center for Individualized Medicine has developed a sequencing technology to […]

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Tags: antibacterial resistance, antibiotic, Center for Individualized Medicine, DNA, Emma Whittle, genomics, gut health, infection, infectious disease, microbiome, RNA


August 4, 2020

Phage therapy shows potential for treating prosthetic joint infections

By Susan Murphy Susan Murphy (@susanmurphy)

Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research. The findings suggest phage therapy could provide a potential treatment for managing such infections, including those involving antibiotic-resistant microbes. The research is published in the July 23 issue of Clinical Infectious Diseases (CID). “The treatment for […]

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Tags: antibacterial resistance, bacteriophages, Center for Clinical and Translational Science, Center for Individualized Medicine, collaboration, Gina Suh, infectious disease, phage, prosthesis, research, Robin Patel


May 18, 2020

Mayo Clinic Research in the News — Week in Review 5/18/2020

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Mayo Clinic researchers continue to share both their expertise and their research findings in regional, national and international news. Collected here are links and snippets from some of the stories from around the world. They connect Mayo Clinic research and international efforts to understand and reduce the devastating effects of the SARS-CoV-2 virus and COVID-19. Data […]

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Tags: antibacterial resistance, antibodies, artificial intelligence, cardiology, cardiovascular medicine, clinical trials, COVID-19, Gianrico Farrugia, heart failure, infectious disease, Mayo Clinic Health System, Michael Joyner


January 9, 2020

In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test

By Susan Murphy Susan Murphy (@susanmurphy)

For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]

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Tags: antibacterial resistance, basic science, biomedical engineering, Center for Individualized Medicine, deep space medicine, genomics, Heidi Nelson, infectious disease, Marina Walther-Antonio, Nicholas Chia, Robin Patel, sepsis


December 5, 2017

MASTERMIND: A Smarter Search for Microbial Diagnostics

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Barbara J. Toman In the war against microbes, human beings are vastly outnumbered—and losing the weapons race. The introduction of antibiotics into clinical practice in the 1940s spurred hope that infectious diseases might be defeated as a public health problem. But bacterial microbes are cunning foes, adept at acquiring resistance to antibiotics faster than […]

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Tags: antibacterial resistance, clinical trials, infectious disease, Robin Patel


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