Items Tagged ‘basic science’
May 20, 2021 · Leave a Comment
Diagnostic test — Matthew Binnicker, Ph.D., reflects on a lab in a pressure cooker
By Advancing the Science contributor 
Matthew Binnicker, Ph.D., director of the Clinical Virology Laboratory in the Division of Clinical Microbiology at Mayo Clinic in Rochester, has been involved in his fair share of viral outbreaks. He led a team that worked to develop a test for the Zika virus outbreak in 2016. He was involved in planning for patients during […]
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Tags: basic science, biomedical research, collaboration, COVID-19, Department of Laboratory Medicine and Pathology, discovery research, Matthew Binnicker, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic Laboratories, virology
March 1, 2021 · Leave a Comment
Mayo Clinic Research in the news — 3/1/2021
Media coverage of Mayo Clinic research and expertise covered home cancer screening tests, youth vaping, several advancements in women’s health, COVID-19 and many other topics. Read on for excerpts and links to the articles. Putting Faith Into Heart Health Minnesota Women’s Press, 2/25/2021 Dr. LaPrincess Brewer, a cardiologist at Mayo Clinic in Rochester, grew up […]
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Tags: addiction research, Alzheimer's disease, Aminah Jatoi, anaphylaxis, arthritis, basic science, bladder cancer, BRCA1, BRCA2, cancer screening, clinical research, cognitive impairment
February 12, 2021 · Leave a Comment
Body fat investigation provides insights for ‘obesity paradox’
The Obesity Paradox Excerpted from a 2009 Mayo Clinic Proceedings article, The Obesity Paradox: Perception vs Knowledge. “Data from several epidemiological studies, including the Framingham Heart Study, have found a positive relationship between obesity and mortality, in particular cardiovascular mortality. However, several cross-sectional, retrospective database studies … have found an inverse correlation between body mass […]
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Tags: animal model, basic science, biomedical research, discovery research, gastroenterology, molecular biology, obesity, pancreatitis, Vijay Singh
January 27, 2021 · Leave a Comment
By Advancing the Science contributor
Targeting mitochondria is a promising therapeutic strategy, study shows “Mitochondria are the powerhouses of the cell.” Many a young science student has heard that truism. “Mitochondria are extremely important because they ensure that we have energy supply for cells to conduct functions,” says Mayo Clinic researcher Eugenia Trushina, Ph.D. “Otherwise, we would all be dead […]
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Tags: Alzheimer's disease, animal model, basic science, clinical trials, discovery research, drug discovery, Eugenia Trushina, Kogod Center on Aging, Minnesota Partnership, mitochondria, National Cancer Institute, National Institutes of Health
September 17, 2020 · Leave a Comment
Could regenerative medicine hold a key to understanding Alzheimer’s disease?
September is World Alzheimer’s Month, a time to raise awareness of research to unlock scientific mysteries around a disease that robs people of their memory, independence and ultimately their ability to think and reason. Focused on disease causes and cures, the Center for Regenerative Medicine is driving innovation as a collaborative partner in Mayo Clinic’s […]
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Tags: Alzheimer's disease, basic science, Center for Regenerative Medicine, dementia, discovery research, Guojun Bu, Melissa Murray, neurology, neurosciences, stem cells
August 7, 2020 · Leave a Comment
Research News Roundup — July 2020
It sometimes seems that summer has flown by without any significant achievements, and only incremental evidence building in the topic of the moment. COVID-19 has had a major dampening effect on social interaction, one doesn’t need to be a researcher to figure that out. However, biomedical and health care delivery research have not paused for […]
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Tags: antibodies, bacteriophages, basic science, blood clots, CAR-T, COVID-19, discovery research, immunity, non-Hodgkin lymphoma, phage, prosthesis, Research News Roundup
August 6, 2020 · Leave a Comment
Calcium Signaling in Microglia: Implications for Brain Diseases?
By Sara Tiner 
Calcium helps nerves and muscles “fire,” signaling cells to do something like contract a muscle or release a neurotransmitter in the brain. But in one type of brain cell, microglia, this calcium signaling seemed absent. Researchers have long wondered why microglia don’t seem to rely on calcium signaling and now, with a recent publication in […]
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Tags: animal model, Anthony Umpierre, basic science, cell signaling, discovery research, Gregory Worrell, Long-Jun Wu, neurology, neurosciences, Yanlu Ying
April 23, 2020 · Leave a Comment
Antimalarials, COVID-19, cardiac arrest
Over the last few weeks, chloroquine and hydroxychloroquine have become household words. These antiparasitic drugs normally prescribed for malaria were introduced early in the rush to find potential treatments for COVID-19. As time goes on, the public discussion has centered on who should get these particular drugs and when. Meanwhile many doctors and medical researchers […]
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Tags: basic science, COVID-19, discovery research, Michael Ackerman
April 20, 2020 · Leave a Comment
Mayo Clinic Research in the news: Week in review 4/20/2020
Many of us have passed another week of “stay at home” but others are on the front lines of patient care and COVID-19 research. How does it spread? Why do some people contract more serious cases, or develop more antibodies? How many people have been exposed? These are just a few of the questions Mayo […]
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Tags: Andrew Badley, antibodies, basic science, biomedical research, cardiology, Colin West, COVID-19, Department of Laboratory Medicine and Pathology, Elitza Theel, Gregory Poland, immune system, immunity
April 16, 2020 · Leave a Comment
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins to reverse […]
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Tags: Andre Terzic, basic science, cardiac regeneration, cardiovascular disease, Center for Regenerative Medicine, discovery research, heart attack, heart failure, Kent Arrell, mesenchymal stem cells, stem cells