Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘basic science’

February 26, 2019

Bone Marrow Stem Cells Stall Out in Chronic Lymphocytic Leukemia

By Sara Tiner saratiner

For patients who have chronic lymphocytic leukemia, fighting off a serious infection can be difficult and often is just not possible. And a team of Mayo researchers is starting to find out why in a paper published recently in the journal Leukemia. What is Chronic Lymphocytic Leukemia? This disease is cancer of an immune cell […]

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Tags: basic science, blood cancer, cancer, Center for Biomedical Discovery, chronic lymphocytic leukemia, immunology, Kay Medina, leukemia, Mayo Clinic Cancer Center, Neil Kay, Wei Ding


February 12, 2019

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles susanbuckles

Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]

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Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma


February 7, 2019

Eva Galanis, M.D.-Bitten by the virotherapy bug

By Advancing the Science contributor advancingthescience

Every day more than 1,600 Americans die from cancer. Most of them have cancer that can’t be cured with traditional methods — surgery, radiation and chemotherapy. The father of Evanthia Galanis, M.D., was one of them. He died in the late 1990s from melanoma when his daughter was a junior faculty member at Mayo Clinic. “My father would have […]

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Tags: basic science, cancer, clinical trials, Eva Galanis, gene therapy, hematology, immunotherapy, Mayo Clinic Cancer Center, measles virus, oncology, SPORE, virotherapy


February 5, 2019

Research News Roundup-January 2019

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Minnesota Partnership awards 5 collaborative research grants Diabetes, stress-induced aging and Alzheimer’s disease, immigration-related obesity, and implantable drug […]

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Tags: artificial intelligence, basic science, biomarkers, cancer, cervical cancer, clinical trials, concussion, heart failure, hockey, James Kirkland, Kathy MacLaughlin, Kogod Center on Aging


January 7, 2019

One more gift for you in the new year

By Elizabeth Zimmermann elizabethzimmermann

Were you good last year? If so (or even if not – we don’t judge) you might enjoy these little gifts of new knowledge, ideas, technology, and more from Mayo Clinic Research. Read on to learn about some of our newest research programs. Explore some of our shiniest websites (so new the dust hasn’t had […]

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Tags: basic science, biomedical research, cancer, Center for Biomedical Discovery, E. Aubrey Thompson, Ian Lanza, Jan van Deursen, Jian Yuan, Kathleen Yost, Kay Medina, Kenton Kaufman, liver cancer


December 4, 2018

Research News Roundup — November 2018

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. How viruses hijack part of your immune system and use it against you An enzyme intended to prevent autoimmune disease can be […]

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Tags: augmented human intelligence, basic science, Bradley Erickson, brain tumor, cancer, Geoffrey Johnson, Mayo Clinic Alix School of Medicine, Mayo Clinic Nicotine Dependence Center, Mayo Clinic School of Medicine, neurology, prostate cancer, radiology


November 15, 2018

Meet Lisa Schimmenti: Searching for drug therapies to treat hearing loss

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog on Oct. 4, 2018 Article by Sharon Rosen   Lisa Schimmenti, M.D. has always been fascinated with Helen Keller and all she accomplished, in spite of being blind and deaf from a very young age. As the newly appointed chair of Mayo Clinic’s Department of […]

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Tags: basic science, Center for Individualized Medicine, genetics, Lisa Schimmenti, zebrafish


October 1, 2018

How Bread Yeast and Book Damage Help Clarify Epigenetics

By Sara Tiner saratiner

Genes don’t change, but how they are used by the body can.  That shift in use (which is called epigenetics) can mean the difference between illness and health. To better understand how that happens Mayo researchers are examining how genes are activated (used) and copied. With a recent publication in the journal Science, a team […]

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Tags: basic science, Center for Individualized Medicine, Chuanhe Yu, DNA, epigenetics


August 21, 2018

‘Gut touch?’ Mayo Clinic researchers discover important trigger for serotonin release

By Advancing the Science contributor advancingthescience

Researchers at Mayo Clinic have discovered an important mechanical trigger in the gut for releasing serotonin in the body. Serotonin is an important hormone and neurotransmitter in the human body, believed to help regulate digestion, appetite, mood, social behavior, sleep and other important functions. The researchers’ findings were published this week in the Proceedings of the National […]

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Tags: Arthur Beyder, basic science, gastroenterology, gut health, Mayo Clinic Proceedings


August 8, 2018

New pathway in prostate cancer cells suggests possible therapy

By Sara Tiner saratiner

Expanding on previous findings, a group of Mayo researchers continue using discovery research in cells to find options for treating cancers. In their most recent paper, published in Molecular Cell, the team’s research suggest that a drug used for breast cancer may be helpful in some types of prostate cancers. “In the current study we […]

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Tags: basic science, biomedical research, gene mutation, Haojie Huang, Mayo Clinic Cancer Center, prostate cancer


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