Items Tagged ‘basic science’
April 23, 2020
Antimalarials, COVID-19, cardiac arrest
Over the last few weeks, chloroquine and hydroxychloroquine have become household words. These antiparasitic drugs normally prescribed for malaria were introduced early in the rush to find potential treatments for COVID-19. As time goes on, the public discussion has centered on who should get these particular drugs and when. Meanwhile many doctors and medical researchers […]
Tags: basic science, COVID-19, discovery research, Michael Ackerman
April 20, 2020
Mayo Clinic Research in the news: Week in review 4/20/2020
Many of us have passed another week of “stay at home” but others are on the front lines of patient care and COVID-19 research. How does it spread? Why do some people contract more serious cases, or develop more antibodies? How many people have been exposed? These are just a few of the questions Mayo […]
Tags: Andrew Badley, antibodies, basic science, biomedical research, cardiology, Colin West, COVID-19, Department of Laboratory Medicine and Pathology, Elitza Theel, Gregory Poland, immune system, immunity
April 16, 2020
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins to reverse […]
Tags: Andre Terzic, basic science, cardiac regeneration, cardiovascular disease, Center for Regenerative Medicine, discovery research, heart attack, heart failure, Kent Arrell, mesenchymal stem cells, stem cells
March 17, 2020
Regenerating missing bacteria for healthier lungs
Connection to COVID-19 People with COPD are at a greater risk of contracting COVID-19, and likely to experience much worse cases than people with healthy lungs. To help alleviate concerns, the COPD Foundation has set up a continuous blog with expert answers to questions related to COPD. In addition, the Centers for Disease Control and […]
Tags: basic science, Center for Regenerative Medicine, COPD, COVID-19, discovery research, lung disease, Regenerative Medicine Minnesota, Veena Taneja
February 3, 2020
Merging minds to accelerate research discovery
By Advancing the Science contributor 
Mayo Clinic and Arizona State University formed the Mayo Clinic and Arizona State University Alliance for Health Care in 2010 to merge minds and accelerate research discoveries, improve patient care through innovation and transform medical education to enhance health outcomes. Highlights of two of the joint research efforts follow. Identifying a blood-based biomarker for early-stage […]
Tags: Alzheimer's disease, Arizona State University, basic science, biomarkers, Charles Adler, infectious disease, Michael Sierks, MRSA, Parkinson's disease, Robin Patel
January 23, 2020
Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders
A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research in animal models could advance an already approved Food and Drug Administration therapy and also could lead to new strategies for treating diseases of the central nervous […]
Tags: Alzheimer's disease, autoimmune disorder, basic science, Center for Regenerative Medicine, demyelination, discovery research, Isobel Scarisbrick, multiple sclerosis, neurology, schizophrenia, spinal cord injury
January 22, 2020
What’s Next for The Research of the Future
By Sara Tiner 
Breakthroughs in medical science rarely burst on the scene. Behind every advance is years of work by dogged researchers who nurtured the seed of idea until it flowered, bore fruit and materialized into a better treatment, device or therapy for patients. Here is where those seeds start: More than a dozen projects related to cancer, […]
Tags: Anthony Windebank, basic science, cancer, cancer genomics, Center for Biomedical Discovery, Christopher Evans, Christopher Groen, Daniel Billadeau, Daniel Tschumperlin, discovery research, Eva Morava-Kozicz, fibrosis
January 9, 2020
In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test
By Susan Murphy
For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]
Tags: antibacterial resistance, basic science, biomedical engineering, Center for Individualized Medicine, deep space medicine, genomics, Heidi Nelson, infectious disease, Marina Walther-Antonio, Nicholas Chia, Robin Patel, sepsis
January 8, 2020
Mentoring, science fair ignite SPARK in high school students
By Advancing the Science contributor
Growing up, Rishi Misra watched his grandmother add fragrant Indian spices to family meals. In ninth grade, Misra came across a study showing that these spices have antibacterial properties. This piqued his interest in science – a curiosity being nurtured by Mayo Clinic’s research mentoring program known as SPARK. SPARK stands for Science Program for the Advancement […]
Tags: basic science, Dev Mukhopadhyay, John Copland III, Keith Knutson, Panos Anastasiadis, research, research education, Ruifeng Lu, Tushar Patel, Vijay Madamsetty
November 21, 2019
Getting to the heart of cancer treatment side effects
By Advancing the Science contributor
By Sara Nick Cancer care has come a long way in recent decades, with some types achieving survival rates of 90% or more. But longer survival times have introduced new consequences: namely, common cancer treatments can lead to an increased risk of serious heart problems later on. “Chemotherapy and radiation are lifesaving, but we’re playing […]
Tags: basic science, biobank, cardiology, Carolyn Landolfo, collaboration, DeLisa Fairweather, discovery research, genetic testing, genetics, Jordan Ray, Mayo Clinic Cancer Center, Nadine Norton