Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘basic science’

August 8, 2018

New pathway in prostate cancer cells suggests possible therapy

By Sara Tiner saratiner

Expanding on previous findings, a group of Mayo researchers continue using discovery research in cells to find options for treating cancers. In their most recent paper, published in Molecular Cell, the team’s research suggest that a drug used for breast cancer may be helpful in some types of prostate cancers. “In the current study we […]

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Tags: basic science, biomedical research, gene mutation, Haojie Huang, Mayo Clinic Cancer Center, prostate cancer


August 7, 2018

Senescent cells and aging: Following up on the unexpected pays off

By Advancing the Science contributor advancingthescience

Starting at age 8, Jan van Deursen, Ph.D., helped his carpenter father on the weekends when he built custom staircases, windows and doors for people in their village in the Netherlands. “My father had a fast pace, and I had to keep up with him,” says Dr. van Deursen. “I didn’t realize it at the time, […]

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Tags: aging, basic science, cancer, Jan van Deursen, Nature, senescent cells


August 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In adults over 70, exposure to general […]

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Tags: aging, Alzheimer's disease, basic science, DNA, genomics, Mayo Clinic Proceedings, Mayo Clinic Study of Aging, neurology, ovarian cancer, precision medicine, Research News Roundup


July 30, 2018

What’s new on the web?

By Elizabeth Zimmermann elizabethzimmermann

At Mayo Clinic, research is integral to everything we do. We would be unable to offer the highest possible levels of care and continually improve the practice of medicine without research, and the education programs and processes that underpin our care. Our research web is actually just a section of Mayo Clinic’s internet presence, but today we’re sharing some […]

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Tags: basic science, Center for Clinical and Translational Science, HLHS, hypoplastic left heart syndrome, Kristin Zhao


July 10, 2018

Using biological particles from milk to target liver cancer

By Kate Ledger k8ledger

Among cancers, liver tumors have been particularly hard for doctors to treat. The cancer cells tend to be hardy from the beginning and even undergo changes that make them more resistant to chemotherapies. What’s clear is that an effective treatment needs to reach the cancer cells, and not affect or damage the normal liver. The […]

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Tags: basic science, Center for Regenerative Medicine, liver cancer, Mayo Clinic Cancer Center, Tushar Patel


July 5, 2018

Research News Roundup-June 2018

By Elizabeth Zimmermann elizabethzimmermann

Each month, we publish Mayo Clinic’s Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month’s Roundup includes a number of findings related pancreatic cancer and other gastrointestinal disorders, as well […]

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Tags: basic science, cancer, Center for Individualized Medicine, constipation, diabetes, DNA, DNA testing, gastroenterology, gene mutation, genetic testing, liver cancer, pancreatic cancer


June 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Brudos Ferrara nicoleferrara

Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, M.D., M.B., B.Ch., a specialist […]

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Tags: basic science, Center for Individualized Medicine, DNA, Ferga Gleeson, gastroenterology, individualized medicine, pancreatic cancer, precision medicine


April 24, 2018

Why mentor? One researcher’s story

By Elizabeth Zimmermann elizabethzimmermann

In medical research at Mayo Clinic, as in all other fields here, diversity is welcome. Each person brings unique perspectives, experiences and knowledge. However, while there are known benefits for an organization that has diverse teams, individual team members sometimes find their greatest satisfaction and professional success comes from having mentors with like backgrounds. Research […]

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Tags: basic science, Joy Wolfram, medical research education, research education


April 17, 2018

Plasma ceramides-A promising new diagnostic tool for cardiology

By gmchiri gmchiri

Low-density lipoprotein (LDL) cholesterol is the primary measure of atherosclerotic risk and thus a therapeutic target in clinical practice. The focus on LDL cholesterol and its control by diet, lifestyle, and pharmaceuticals has contributed to a significant and sustained reduction in blood concentrations of total and LDL cholesterol among U.S. adults since 1988. Despite population-wide […]

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Tags: basic science, cardiology, heart disease, Jeffrey Meeusen, Mayo Clinic Laboratories


April 9, 2018

Sara Busatto – A different kind of Florida visitor

By Elizabeth Zimmermann elizabethzimmermann

Not there to check out the beaches or fantasy amusement parks, Sara Busatto has a different reason from many to be in Florida. She is a visiting student at the Mayo Clinic Graduate School of Biomedical Sciences, in Jacksonville, Florida. Currently in the final year of her Ph.D. in health care technology at the University […]

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Tags: basic science, Joy Wolfram, nanomedicine, research education


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