Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘biomarkers’

February 18, 2020

Mayo researchers studying ‘promising’ new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy Susan Murphy

A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]

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Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine


February 3, 2020

Merging minds to accelerate research discovery

By Advancing the Science contributor Advancing the Science contributor

Mayo Clinic and Arizona State University formed the Mayo Clinic-Arizona State University Alliance for Health Care in 2010 to merge minds and accelerate research discoveries, improve patient care through innovation and transform medical education to enhance health outcomes. Highlights of two of the joint research efforts follow. Identifying a blood-based biomarker for early-stage Parkinson’s disease […]

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Tags: Alzheimer's disease, Arizona State University, basic science, biomarkers, Charles Adler, infectious disease, Michael Sierks, MRSA, Parkinson's disease, Robin Patel


January 30, 2020

A breakthrough in distinguishing benign adrenal tumors from cancerous ones

By Advancing the Science contributor Advancing the Science contributor

By Christoph Bahn Approximately 80 million CT scans are performed in the United States every year. Adrenal tumors are found incidentally in about 5% of these scans. Most of these tumors will turn out to be benign, but a small fraction will be adrenal cortical carcinoma, a type of cancer with high mortality and frequent recurrence; even for […]

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Tags: adrenal tumors, biomarkers, biopsy, cancer, clinical research, CT, endocrine cancer, endocrinology, epidemiology, hormones, Irina Bancos, Mayo Clinic Laboratories


July 10, 2019

Biomarkers could help early diagnosis of Alzheimer’s

By Advancing the Science contributor Advancing the Science contributor

Early diagnosis will ultimately be essential in the management and treatment of Alzheimer’s disease. Examination of Alzheimer’s biomarkers can improve the prediction of short-term memory decline in middle-age and elderly individuals, according to new research led by Mayo Clinic.

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Tags: Alzheimer's disease, biomarkers, Clifford Jack Jr, Mayo Clinic Study of Aging, Rochester Epidemiology Project


April 3, 2019

Research News Roundup-March 2019

By Elizabeth Zimmermann Elizabeth Zimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research news releases from the past month. It also connects readers to related resources. Read on for more information from Mayo Clinic Research. Removal of ‘zombie cells’ alleviates causes of diabetes in obese mice Mayo Clinic researchers and their collaborators have shown that when senescent […]

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Tags: AFib, aging, Alzheimer's disease, atrial fibrillation, biomarkers, cancer, Center for the Science of Health Care Delivery, clinical trials, diabetes, gastroenterology, hepatitis, JAMA


February 5, 2019

Research News Roundup-January 2019

By Elizabeth Zimmermann Elizabeth Zimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Minnesota Partnership awards 5 collaborative research grants Diabetes, stress-induced aging and Alzheimer’s disease, immigration-related obesity, and implantable drug […]

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Tags: artificial intelligence, basic science, biomarkers, cancer, cervical cancer, clinical trials, concussion, heart failure, James Kirkland, Kathy MacLaughlin, Kogod Center on Aging, Mayo Clinic Proceedings


November 8, 2018

MS or not MS? Mayo Clinic Neuroimmunology Lab answers the question

By Advancing the Science contributor Advancing the Science contributor

In 2017, Mayo Clinic launched a first-in-the-U.S. clinical test to help patients with some autoimmune disorders get the right diagnosis faster. The test defines a new form of inflammatory demyelinating disease, myelin oligodendrocyte glycoprotein (MOG) autoimmunity, which is distinct from multiple sclerosis (MS), with which it is commonly confused. The test uses live cells to […]

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Tags: acute flaccid myelitis, Andrew McKeon, biomarkers, Department of Laboratory Medicine and Pathology, MOG antibody, multiple sclerosis, neuroimmunology, neurology, Sean Pittock, transverse myelitis, Vanda Lennon


July 19, 2018

A clearer picture: new imaging technologies advance diagnosis, individualized care

By Susan Buckles Susan Buckles

New imaging technologies are advancing diagnosis and individualizing care. Imaging tests – such as a CT scan or MRI – are essential tools that health care providers use to answer complex and challenging questions. Gabriel Krestin, M.D., Ph.D., a radiologist and researcher, is at the forefront of new efforts to apply cutting edge imaging technologies […]

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Tags: biomarkers, Center for Individualized Medicine, individualized medicine, Individualizing Medicine Conference, Kiaran McGee, radiology


November 2, 2017

Targeting a Molecular Abnormality

By Nicole Ferrara Nicole Ferrara

Microsatellite instability (MSI) might sound like something a NASA engineer would study. But it’s actually a molecular abnormality found in 15 percent of colorectal cancers, explains Mayo Clinic medical oncologist and gastroenterologist Frank A. Sinicrope, M.D., who is testing an immunotherapy drug that could help patients with this subtype of colorectal cancer. Just recently, researchers […]

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Tags: biomarkers, clinical trials, Forefront, Mayo Clinic Cancer Center


March 15, 2016

New Treatment-Sequencing Based on Biomarker Elevation in Pancreatic Cancer

By Meghan Knoedler Meghan Knoedler

Pancreatic cancer is the fourth leading cause of death in men and women and is projected to increase to the second leading cause of death by 2020 if there are not significant treatment advances made. Our current understanding of pancreatic cancer suggests that it is a systemic disease in most patients, meaning, that by the time of […]

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Tags: biomarkers, Center for the Science of Health Care Delivery, Elizabeth Habermann, John (Jay) Bergquist, Mark Truty, pancreatic cancer, surgery, surgical outcomes


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