Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘cancer genomics’

December 2, 2020

Conquering cancer by targeting its genetic abnormalities

By Susan Murphy Susan Murphy

Joanne Garnett has harrowing memories of that life-changing day back in 1981. She was a 39-year-old land use planner living in Wyoming when she received a call from her doctor confirming she had uterine cancer.  “I was shocked, and it was strange because I didn’t fit any profile for uterine cancer,” Garnett recalls. “I got a […]

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Tags: BRCA2, breast cancer, cancer genomics, Center for Individualized Medicine, clinical research, DNA, gene mutation, genetic testing, hereditary cancer, Lynch syndrome, Mayo Clinic Cancer Center, Niloy "Jewel" Samadder


November 18, 2020

Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations

By Susan Murphy Susan Murphy

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. In a new study published in JAMA Oncology, scientists with Mayo Clinic’s Center for Individualized Medicine conducted genetic testing in more than 3,000 patients who were diagnosed with cancer at Mayo Clinic Cancer Center locations […]

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Tags: cancer genomics, genetic testing


October 29, 2020

Developing solutions for early detection of pancreatic cancer

By Advancing the Science contributor Advancing the Science contributor

By Lisa Newkirk Pancreatic cancer is one of the deadliest forms of cancer, but patients who are diagnosed at an early stage can survive five years or longer. A team at Mayo Clinic is developing patient-centered solutions for early detection of pancreatic cancer using artificial intelligence and biomarkers. This year, over 57,000 Americans will be […]

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Tags: artificial intelligence, biomarkers, cancer genomics, cancer screening, collaboration, CT, DNA, Gloria Petersen, Mayo Clinic Cancer Center, pancreatic cancer, patient experience, Shounak Majumder


August 20, 2020

Could population genetic screening improve public health?

By Colette Gallagher Colette Gallagher

Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]

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Tags: breast cancer, cancer genomics, Center for Individualized Medicine, genetic testing, genetics, hereditary cancer, hereditary diseases, Lynch syndrome, Matthew Ferber, ovarian cancer, population health


May 1, 2020

Non-COVID research in the news, 5/1/2020

By Advancing the Science contributor Advancing the Science contributor

Although the week’s coverage has largely consisted of COVID-19 news, closer inspection finds it peppered with Mayo Clinic research on some other topics. We’ve collected a few of the news clips for ease of review. Read on for findings in cancer, deep vein thrombosis and Alzheimer’s disease: cfDNA Assay Shows Predictive Value in Detecting Cancer, […]

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Tags: Alzheimer's disease, cancer, cancer genomics, David Thiel, deep vein thrombosis, DNA, Guojun Bu, Rosa Rademakers


February 18, 2020

Mayo researchers studying ‘promising’ new approach to treating advanced cancer, 1 patient at a time, 1 tumor at a time

By Susan Murphy Susan Murphy

A collaborative team of Mayo Clinic scientists is studying an innovative strategy for treating advanced cancer, using genomics and human tumor samples as their guide. The novel approach, called Ex Vivo, creates a miniature cancer replica for testing therapies outside a patient’s body, combined with a comprehensive genomic analysis of a patient’s cancer cells. “We […]

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Tags: biomarkers, cancer, cancer genomics, Center for Individualized Medicine, genomics, George Vasmatzis, individualized medicine, Mayo Clinic Cancer Center, Minetta Liu, Panos Anastasiadis, personalized medicine


January 22, 2020

What’s Next for The Research of the Future

By Sara Tiner Sara Tiner

Breakthroughs in medical science rarely burst on the scene. Behind every advance is years of work by dogged researchers who nurtured the seed of idea until it flowered, bore fruit and materialized into a better treatment, device or therapy for patients. Here is where those seeds start: More than a dozen projects related to cancer, […]

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Tags: Anthony Windebank, basic science, cancer, cancer genomics, Center for Biomedical Discovery, Christopher Evans, Christopher Groen, Daniel Billadeau, Daniel Tschumperlin, discovery research, Eva Morava-Kozicz, fibrosis


January 7, 2020

Research News Roundup–December 2019

By Elizabeth Zimmermann Elizabeth Zimmermann

December’s Research News Roundup highlights a number of advancements in understanding and treating different cancers, including blood, breast and gastrointestinal; in addition to other research news from Mayo Clinic. The Roundup also connects readers to related resources. Read on for more information from Mayo Clinic Research. Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal […]

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Tags: breast cancer, cancer, cancer genomics, CAR-T, cardiovascular medicine, chemotherapy, chronic lymphocytic leukemia, colorectal cancer, endometrial cancer, gastrointestinal cancer, hematology, Mayo Clinic Cancer Center


September 4, 2019

Mayo experts provide insights into how genes affect medication response

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response […]

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Tags: breast cancer, cancer, cancer genomics, Center for Individualized Medicine, Eric Matey, Lauren Cornell, mental health, Michael Shuh, neurology, opioids, pharmacogenomics, pharmacy


March 21, 2019

Colon cancer: a new era in cancer screening and detection

By Susan Buckles Susan Buckles

March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]

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Tags: cancer genomics, Center for Individualized Medicine, colon cancer, hereditary cancer, Lynch syndrome, Niloy "Jewel" Samadder, precision medicine


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