Items Tagged ‘cancer research’
September 27, 2022
Physician-scientist investigates dual CAR-T cell therapy for multiple myeloma cancer
By Susan Murphy 
Leo Sakemura, M.D., Ph.D., a physician-scientist in Mayo Clinic’s Division of Hematology, is working to advance immunotherapy efficacy in multiple myeloma by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment. Dr. Sakemura’s previous […]
Tags: cancer genomics, cancer research, CAR-T cell therapy, Center for Individualized Medicine, hematology, immunotherapy, Leo Sakemura, metabolomics, multiple myeloma
September 1, 2022
Meet Yan Bi, M.D., Ph.D. — Physician and Scholar
By Advancing the Science contributor
Originally from China, Yan Bi, M.D., Ph.D., now lives in Florida. She holds a clinical appointment in Gastroenterology and Hepatology at Mayo Clinic in Jacksonville, where she treats patients with a variety of gastrointestinal disorders. As one might surmise from her doctoral degrees, Dr. Bi is a lifelong learner. Today she seeks to apply her […]
Tags: artificial intelligence, cancer research, cancer screening, Center for the Science of Health Care Delivery, Che Ngufor, clinical research, collaboration, data science, gastroenterology, Kern Health Care Delivery Scholars, Michael Wallace, pancreatic cancer
January 19, 2022
By Susan Murphy
Immunotherapy has given some patients a better outcome with mesothelioma, an aggressive cancer in the lining around the lungs that has been linked to asbestos exposure. The individualized therapy can stimulate the body’s immune system to attack cancer cells and prolong life. But it doesn’t always work, and some patients experience significant side effects. Now, Mayo Clinic Center for Individualized Medicine researchers may […]
Tags: Aaron Mansfield, cancer genomics, cancer research, Center for Individualized Medicine, genomics, mesothelioma
January 12, 2022
10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021
By Susan Murphy
It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physicians have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, […]
Tags: artificial intelligence, cancer research, Center for Individualized Medicine, genetic testing, genomics, rare disease
October 26, 2021
By Susan Murphy
When Michelle Ewy, 38, received an opportunity at Mayo Clinic to get her DNA tested for genetic mutations related to breast and ovarian cancers, and other cancers and diseases, she jumped at the chance. “I wasn’t thinking much of what the outcome would be because there has not been a prevalence of breast or ovarian […]
Tags: BRCA2, breast cancer, cancer research, Center for Individualized Medicine, genetic counseling, genetic testing, genome, hereditary cancer, Konstantinos Lazaridis, Lynch syndrome, ovarian cancer
June 2, 2021
Researchers develop new technique to study ‘microcancers’ and screen cancer-fighting drugs
By Advancing the Science contributor
A team from the University of Illinois Urbana-Champaign’s Grainger College of Engineering and Mayo Clinic have developed a new technique for creating “microcancer” cell cultures. It allows researchers to form hundreds of microcancers in a high-throughput format using a small, microfabricated chip, enabling direct measurement of cell health or response to drugs. It also allows […]
Tags: cancer research, Farhad Kosari, genomics, George Vasmatzis, Panos Anastasiadis, University of Illinois Urbana-Champaign
May 25, 2021
Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients
By Susan Murphy
A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next. In the study, published in Clinical Gastroenterology and Hepatology, researchers within the Mayo Clinic Center for Individualized Medicine found 1 in 6 patients with colorectal cancer had an inherited cancer-related gene […]
Tags: cancer research, colon cancer, genetic testing, hereditary cancer, Niloy "Jewel" Samadder
January 4, 2021
Research News Roundup – Q4 2020
The year 2020 was a time during which medical and many other researchers around the world focused much of their attention and effort on a single topic – the SARS-CoV-2 virus and related COVID-19 viral infection. However, other research continued, findings were published, and evidence built for improvements in health outcomes and delivery of health […]
Tags: antibiotic, artificial intelligence, brain, cancer research, cardiology, cardiovascular medicine, Center for Individualized Medicine, Center for the Science of Health Care Delivery, clinical research, clinical trials, collaboration, coronary artery disease
November 19, 2020
Breast cancer accurately staged with fewer lymph nodes
When a person is diagnosed with breast cancer, surgery can be their first treatment. Other times, their clinician will prescribe chemotherapy before surgery, called neoadjuvant chemotherapy. In both cases, for patients with clinically negative nodes at presentation, surgeons will determine at the time of surgery how far the cancer has spread by removing and examining […]
Tags: breast cancer, Brittany Murphy, cancer research, Center for the Science of Health Care Delivery, chemotherapy, Judy Boughey, lymphatic system, lymphedema, Mayo Clinic College of Medicine and Science, oncology, residency program
October 19, 2020
Mayo Clinic Research in the news — 10/19/2020
The news media recently highlighted a range of interesting topics, featuring Mayo Clinic Research and researchers on a new way to hunt down and capture deadly brain cancer cells, MSG in food, Angelman syndrome, the connection between screen time and life expectancy, COVID-19 (of course), and much more. Read on for brief excerpts and links […]
Tags: acute myeloid leukemia, aging, Angelman syndrome, artificial intelligence, biomarkers, brain cancer, cancer, cancer research, Center for Digital Health, clinical trials, collaboration, COVID-19