July 19, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: Andre Terzic, cardiac regeneration, Center for Regenerative Medicine, heart disease, Kent Arrell, Marriott Family Comprehensive Cardiac Regenerative Program, multiomics, Satsuki Yamada
December 21, 2021
A young father’s regenerative bridge to transplant
Mayo Clinic is pioneering and refining regenerative procedures that are a bridge to transplant. These procedures are providing new options for strengthening and rebuilding health while patients await the gift of life. Organ transplantation is one of the most serious and complex surgeries, but it also can dramatically restore a patient’s health and quality of […]
Tags: Atta Behfar, cardiac regeneration, cardiovascular medicine, Center for Regenerative Medicine, heart transplant, lung regeneration, Steven Graham, Sudhir Kushwaha, transplant, Van Cleve Cardiac Regenerative Medicine Program
August 23, 2021
The importance of individualized regenerative medicine
Individualized screening, guided by artificial intelligence (AI) and biomarkers, can optimize the transformative potential of regenerative medicine, according to a Mayo Clinic study. The paper, published in Biomarkers in Medicine, maintains that using new scientific tools to match the right biotherapeutics to the right patient ushers in the era of achieving tailored regenerative care. Conversely, […]
Tags: Andre Terzic, cardiac regeneration, cardiopoietic stem cells, Center for Regenerative Medicine, Satsuki Yamada, Van Cleve Cardiac Regenerative Medicine Program
February 17, 2021
Advancing cell-based regenerative therapy for heart failure
February is American Heart Month, a time to highlight innovative research that seeks to advance cellular therapy as a new option for restoring heart health. One of the latest discoveries in the Center for Regenerative Medicine and Mayo Clinic Van Cleve Cardiac Regenerative Medicine Program established a way to engineer stem cells that activate regenerative […]
Tags: Andre Terzic, Atta Behfar, biomedical engineering, cardiac regeneration, cardiopoietic stem cells, Center for Regenerative Medicine, clinical trials, heart failure, Mark Li, Mayo Clinic Alix School of Medicine, Mayo Clinic Graduate School of Biomedical Sciences, tissue engineering
April 16, 2020
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells zero in on damaged proteins to reverse […]
Tags: Andre Terzic, basic science, cardiac regeneration, cardiovascular disease, Center for Regenerative Medicine, discovery research, heart attack, heart failure, Kent Arrell, mesenchymal stem cells, stem cells
February 27, 2020
Evolution of cardiac regeneration
By Jen Schutz
February is American Heart Month, a time to acknowledge advancements in a new generation of care. This year focus is placed on repairing damaged heart tissue and restoring heart function after a heart attack. The Mayo Clinic Center for Regenerative Medicine is leading research into cardiac regeneration. Accounting for nearly 20 million of all deaths, heart […]
Tags: Atta Behfar, biomedical research, cardiac regeneration, cardiology, cardiovascular disease, Center for Regenerative Medicine, discovery research, heart attack, heart disease, Michael Sabbah