Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Center for Individualized Medicine’

July 18, 2018

Popular films spark community dialogue about biomedical ethics

By Caitlin Doran caityrosey

When was the last time a movie really made you think, changed how you viewed the world or helped you understand an important topic? Bioethics at the Cinema, organized by the Mayo Clinic Biomedical Ethics Program and the Rochester Public Library, wants to do just that. The goal is to use popular films to create community […]

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Tags: biomedical ethics, biomedical research, Center for Clinical and Translational Science, Center for Individualized Medicine


June 12, 2018

Genetic testing to enhance multiple myeloma treatment

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog on March 6, 2018 Article by Barbara Toman Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month — a time to […]

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Tags: Center for Individualized Medicine, DNA testing, genetic testing, individualized medicine, Keith Stewart, multiple myeloma, precision medicine


May 24, 2018

Mayo’s RIGHT 10K – moving pharmacogenomics into everyday clinical practice

By Susan Buckles susanbuckles

This article originally appeared on the Center for Individualized Medicine blog on March 20, 2018. By Sharon Rosen After nearly half a century of research, Mayo Clinic is a leader in moving pharmacogenomics into clinical practice. This year pharmacogenomics test results for 10,000 Mayo Clinic patients, all participants in the RIGHT 10K study, are being added […]

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Tags: Center for Individualized Medicine, DNA testing, genetics, pharmacogenomics, Richard Weinshilboum


April 10, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher colettegallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. CYP2D6 […]

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Tags: breast cancer, Center for Individualized Medicine, genetic testing, Matthew Goetz, precision medicine


March 15, 2018

Pharmacogenomics testing helps children with acid reflux disease find relief

By Susan Buckles susanbuckles

Article by Sharon Rosen This article originally appeared on the Center for Individualized Medicine blog. Many people have occasional acid reflux or heartburn after eating a heavy or spicy meal. But for children and adults with acid reflux disease, also known as gastroesophageal reflux disease (GERD), the symptoms are more frequent and severe. These patients […]

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Tags: Center for Individualized Medicine, genetic testing, pharmacogenomics


February 22, 2018

Three strikes, then a home run: Paige’s path to a diagnosis

By Susan Buckles susanbuckles

This post originally was published on the Center for Individualized Medicine blog on Dec. 18, 2017. Paige Whorton’s zeal for life is infectious. “I like parasailing, exploring, and zip lining — daredevil stuff,” she says with a giggle. However, pain in her joints, building for years, was slowing her down. “My bones and joints would […]

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Tags: Center for Individualized Medicine, genetic testing


February 13, 2018

4 key things to know about the possibilities, pitfalls of gene editing

By Susan Buckles susanbuckles

ROCHESTER, Minn. — Gene editing has captivated scientists and medical providers with tantalizing visions of wiping out debilitating inherited diseases. Could conditions like Huntington’s disease, for example, be cured by using a tool that acts as a “molecular scissors” to remove and replace disease-causing DNA? Or, would gene editing tempt some to engineer designer babies […]

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Tags: biomedical ethics, Center for Individualized Medicine


January 30, 2018

How does a genomic tumor board impact patient care?

By Colette Gallagher colettegallagher

The outcomes from a Mayo Clinic study published in Oncotarget found value in having an established genomic tumor board, and using genomics for certain patients. The experience of the Genomic Tumor Board has promoted an evolution in the practice according to Alan Bryce, M.D., a Mayo Clinic oncologist, and co-first author on the study. “There is an emerging […]

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Tags: Center for Individualized Medicine, genomics


January 23, 2018

Study evaluates effectiveness of deep genomic profiling in clinical setting

By Colette Gallagher colettegallagher

Genomic profiling is used today for patients with advanced cancers to help develop new ways to diagnose and treat their disease and offer an individualized treatment plan. While gene panel testing is relatively commonplace, there are many barriers to using new and more sophisticated DNA technologies. According to Mitesh Borad, M.D., an oncologist at the Mayo […]

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Tags: Center for Individualized Medicine


January 16, 2018

Genetic tests + coordinated care + research = hope for patients with a genetic neurological disease

By Susan Buckles susanbuckles

  Life with an inherited disease sometimes brings unexpected twists and turns. Five-year-old Gus Erickson has navigated the gyrations with the help of Mayo Clinic’s Neurofibromatosis Clinic. Neurofibromatosis (NF) is a genetic disorder that causes tumors to form on nerve tissue. Those tumors can develop anywhere in the nervous system, including the brain, spinal cord […]

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Tags: Center for Individualized Medicine


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