Items Tagged ‘Center for Regenerative Biotherapeutics’
February 21, 2023
Expanding regenerative biotherapeutics to new practice areas
As a physician at the forefront of new cancer therapies, Yi Lin, M.D., Ph.D., understands the highs and lows that patients experience. Will the latest technologies slow or stop disease? If not, is this the last, best option? Dr. Lin, a hematologist, sees the need for a new class of drugs that provides different treatment […]
Tags: biologics, cancer immunotherapy, CAR-T cell therapy, Center for Regenerative Biotherapeutics, Yi Lin
February 7, 2023
Reprogramming stem cells to heal disease
At one point, Shinya Yamanaka, M.D., Ph.D., was so down and discouraged that he almost gave up his research into embryonic cells and their powerful potential to replace diseased cells. He was finding little interest among colleagues; funding was hard to come by; and research journals rejected his studies. Then, discovery of human embryonic cell […]
Tags: Center for Regenerative Biotherapeutics, induced pluripotent stem cells, Mayo Clinic Symposium on Regenerative Medicine & Surgery, reprogramming cells, Shinya Yamanaka
January 26, 2023
Aspiring to deliver new cures for complex conditions
Mayo Clinic is building toward a future when biologics can cure cancer, kidney disease and diabetes. Mayo marks 2022 as a year of significant strides in accelerating science to make and deliver regenerative biotherapeutics. The goal is to offer new options, based on rigorous research in cell and gene therapies, for disorders with few available […]
Tags: 3D bioprinting, biologics, biomanufacturing, CAR-T cell therapy, Center for Regenerative Biotherapeutics, Julie Allickson, purified exosome product, stromal vascular fraction cells, tissue engineering
January 24, 2023
Florida Research growth and advancements in 2022
By Advancing the Science contributor 
Highlights of Research activities at Mayo Clinic in Florida were included in a Mayo Clinic government relations report to the State of Florida last month. Florida Research continues to grow at a rapid pace. New programs in cancer and biotherapeutics; additional space on campus; significant scientific discoveries in cancer and the neurosciences; and a new […]
Tags: Alfredo Quinones-Hinojosa, Brain Tumor Stem Cell Laboratory, cancer, CAR-T cell therapy, Center for Regenerative Biotherapeutics, chimeric antigen receptor therapy, Hong Qin, Keith Knutson, Mayo Clinic Cancer Center, Mayo Clinic Comprehensive Cancer Center, neurosurgery, Tushar Patel
January 10, 2023
Mayo Clinic opens a second Regenerative Medicine Therapeutic Suites
Mayo Clinic has opened the Regenerative Medicine Therapeutic Suites in Arizona for patients seeking enhanced care when standard procedures don’t meet their needs. The suites are an intersection of clinical practice, research and lab space where patients can have their cells processed on-site for immediate application to their condition. “It’s a whole new level of […]
Tags: bone marrow aspirate concentrate, Center for Regenerative Biotherapeutics, David Lott, platelet rich plasma, Regenerative Medicine Therapeutic Suites, stromal vascular fraction cells, tissue engineering
December 27, 2022
Engineering tissue to strengthen underdeveloped hearts
Could cells taken from a small patch of skin become heart muscle and repair a rare congenital heart defect? It’s a scientific question that Timothy Nelson, M.D., Ph.D., and collaborators hope to answer for those born with an underdeveloped left heart chamber — a rare, complex condition known as hypoplastic left heart syndrome (HLHS). Discovering […]
Tags: cardiomyocytes, Center for Regenerative Biotherapeutics, congenital heart disease, hypoplastic left heart syndrome, induced pluripotent stem cells, Timothy Nelson
December 20, 2022
Registration opens for Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023
Learn the latest in regenerative biotherapeutics, biomanufacturing, regenerative medicine and application to clinical care at the Mayo Clinic Symposium on Regenerative Medicine & Surgery 2023. Registration is now open for the event that will be held April 3–5 at the Westin Kierland Resort and Spa in Scottsdale, Arizona. Regenerative biotherapeutics is an emerging field in […]
Tags: Bruce Levine, Center for Regenerative Biotherapeutics, Harold Ott, Mayo Clinic Symposium on Regenerative Medicine & Surgery, Peter Marks, Raghu Kalluri, Richard Hayden, Shinya Yamanaka
December 13, 2022
Real-world evidence study of regenerative medicine and shoulder surgery
Applying regenerative medicine to a common shoulder surgery could have an impact on the need for follow-up revision surgery in some patients, according to a Mayo Clinic study of real-world evidence. Mayo Clinic researchers analyzed the largest set of data available to determine if adding bone marrow aspirate concentrate to repaired tissue after standard rotator […]
Tags: bone marrow aspirate concentrate, Bradley Schoch, Center for Regenerative Biotherapeutics, Christopher Camp, platelet rich plasma, real world evidence, regenerative medicine, Shane Shapiro, shoulder surgery
November 14, 2022
A step toward a cell-free solution for stress urinary incontinence
Skeletal muscle regenerated and symptoms of stress urinary incontinence improved in preclinical models after use of a cell-free product discovered at Mayo Clinic. In one of the first studies of its kind, Mayo Clinic researchers learned this noncellular approach can restore muscle function and bladder control in preclinical models. The teams of Atta Behfar, M.D., […]
Tags: Atta Behfar, Center for Regenerative Biotherapeutics, Emanuel Trabuco, purified exosome product, stress urinary incontinence
October 31, 2022
LaTonya Hickson, M.D.: Seeking a cellular therapy for chronic kidney disease
Every year, more than 130,000 people in the U.S. are diagnosed with end-stage kidney disease, with most cases caused by diabetes. Newer therapies show promise to slow kidney failure rates, but none stop progression to end-stage kidney failure. The research goal of LaTonya Hickson, M.D., is to develop a cell-based therapy that slows — or […]
Tags: Center for Regenerative Biotherapeutics, chronic kidney disease, diabetic kidney disease, end-stage kidney disease, LaTonya Hickson, nephrology, stem cell research