Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Center for Regenerative Medicine’

May 9, 2022

Regenerating damaged vocal cords

By Susan Buckles Susan Buckles (@susanbuckles)

Cells from amniotic membrane show potential of repairing vocal cord injuries that don’t respond to standard care, Mayo Clinic discovered in preclinical research. The placental membrane provides a rich source of epithelial cells that could regenerate damaged tissue. Research by David Lott, M.D., a laryngeal surgeon in Arizona, found epithelial cells extracted after childbirth triggered […]

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Tags: Center for Regenerative Medicine, David Lott, vocal cord regeneration


April 25, 2022

The immune system and bone regeneration

By Susan Buckles Susan Buckles (@susanbuckles)

Growing up as a student athlete in Cincinnati, Joe Panos had more than his fair share of visits to the orthopedist for sports injuries. The care he received for conditions ranging from pitcher’s elbow to soccer sprains so impressed him that he vowed one day to be the physician instead of the patient. Now Panos, […]

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Tags: bone regeneration, Center for Regenerative Medicine, Christopher Evans, Joe Panos, Mayo Clinic Alix School of Medicine


April 21, 2022

Global spotlight on Mayo Clinic’s regenerative biotherapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic will showcase its work in discovering, manufacturing and delivering next-generation biotherapeutics with an international audience interested in advancing lifesaving cell and gene therapies. Mayo Clinic’s Center for Regenerative Medicine is sponsoring a roundtable discussion, “Mayo Clinic: Building the Ecosystem in Regenerative Biotherapeutics,” at the International Society for Cell & Gene Therapy’s ISCT 2022 […]

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Tags: Center for Regenerative Medicine, Claudia Lucchinetti, International Society for Cell and Gene Therapy, Julie Allickson, Manu Nair, Stephen Ekker, William Faubion Jr.


April 11, 2022

Unleashing the body’s ability to heal

By Susan Buckles Susan Buckles (@susanbuckles)

“We are the patient’s last, best hope,” has been the motto of the Immune, Progenitor and Cell Therapeutics lab, also known as the IMPACT lab, at Mayo Clinic. This lab specializes in clinical and investigative use of cells as living drugs within the body to fight disease and initiate healing when standard therapies don’t work. […]

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Tags: Allan Dietz, CAR-T cell therapy, cellular therapy, Center for Regenerative Medicine, clinical trials, Dennis Gastineau, Franklyn Prendergast, mesenchymal stem cells, perianal fistula, Stanimar Vuk-Pavlovic


March 28, 2022

Regenerative Medicine Minnesota awards 5 research grants to Mayo Clinic

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative Medicine Minnesota, a statewide bipartisan initiative, has awarded five grants to Mayo Clinic investigators to advance new therapeutic options for osteoarthritis, liver disease, rotator cuff injuries and neurological birth defects. People in Minnesota and beyond struggle with chronic diseases such as heart disease, arthritis and diabetes, and standard care doesn’t always ease the symptoms. […]

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Tags: Aaron Krych, animal model, cartilage, cellular therapy, Center for Regenerative Medicine, Chunfeng Zhao, clinical trials, Jennifer Westendorf, liver failure, mesenchymal stem cells, minimally invasive procedure, molecular biology


March 14, 2022

The regenerative operating room of the future

By Susan Buckles Susan Buckles (@susanbuckles)

Envisioning the future of regenerative medicine elicits images of an operating room that also is a manufacturing facility. Patients undergoing surgery could have immediate access to products biomanufactured within the operating room or even within their own bodies. Products such as tissue engineered for targeted healing or 3D-printed scaffolds that repair diseased organs, bones or […]

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Tags: 3D printing, biomanufacturing, Brittany Howard, Center for Regenerative Medicine, David Lott, Juergen Neubauer, laryngeal cancer, larynx transplant, Michael McPhail, Richard Hayden, tissue engineering


February 28, 2022

Preparing to deliver next-generation therapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is among the academic medical centers on the cusp of biomanufacturing next-generation cell and gene therapies that offer hope of new cures for rare and complex diseases. Biomanufacturing this new era of biologic medicines is much different than manufacturing pharmaceuticals from complex molecules. It requires highly specialized lab infrastructure, new processes and new […]

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Tags: Allan Dietz, biomedical engineering, CAR-T cell therapy, Center for Regenerative Medicine, clinical trials, Michael Gustafson, personalized medicine


February 15, 2022

Advancing a new era of regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

Allegorically speaking, if Mayo Clinic were a garden and regenerative technologies were fruits and vegetables, William Faubion Jr., M.D., sees himself as a gardener tending to the teams responsible for these new healing therapies. Dr. Faubion, who is the newly named associate medical director for Mayo Clinic’s Center for Regenerative Medicine, wants to advance discoveries […]

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Tags: Allan Dietz, biomedical engineering, CAR-T cell therapy, Center for Regenerative Medicine, Crohn's disease, Eric Dozois, gastroenterology, immune system, inflammatory bowel disease, perianal fistula, regenerative medicine research, surgery


February 1, 2022

Reimagining stem cell cultivation

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic has discovered how to microencapsulate pluripotent stem cells to potentially make them easier and less expensive to process and more effective for fighting disease. This research by Alexander Revzin, Ph.D., a Mayo Clinic biomedical engineer, is published in Bioactive Materials. “Human pluripotent stem cells hold considerable promise as a source of adult cellsfor […]

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Tags: Alexander Revzin, biomedical engineering, Center for Regenerative Medicine, Regenerative Medicine Minnesota, stem cell research, stem cells


January 18, 2022

Identifying best candidates with avascular necrosis for regenerative alternative to hip replacement

By Susan Buckles Susan Buckles (@susanbuckles)

A regenerative alternative to total hip replacement delayed the need for artificial implants by at least seven years for 35% of patients who had surgery to treat avascular necrosis. That condition occurs when blood flow to the hip joint known as the femoral head is constricted, causing bone cells to die. This Mayo Clinic research, […]

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Tags: biotherapeutics, Center for Regenerative Medicine, hip decompression surgery, hip replacement, orthopedics, Rafael Sierra, regenerative medicine research


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