Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘clinical research’

January 12, 2021

Physicians have new guidelines for managing rare genetic, metabolic disorders

By Susan Murphy Susan Murphy

Physicians now have a blueprint for diagnosing and managing two specific rare inherited metabolic diseases within a group of nearly 150 congenital disorders of glycosylation. These diseases can cause serious and sometimes fatal malfunctions of several organs at or before birth, as well as chronic debilitating symptoms in adults.  The consensus guidelines were published in […]

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Tags: Center for Individualized Medicine, clinical research, Eva Morava-Kozicz, genetics, genomics, hereditary diseases, metabolomics, rare disease


January 6, 2021

Diverse ways regenerative medicine is advancing health care

By Susan Buckles Susan Buckles

Regenerative medicine has contributed to patient care in 2020 more than ever before, bolstered by synergies in research, practice and education. Mayo Clinic’s Center for Regenerative Medicine is at the forefront of a biotherapy revolution in which health care advances from treating disease to restoring health. “The centrality of the body to regenerate itself is […]

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Tags: 3D printing, Andre Terzic, artificial intelligence, Atta Behfar, autoimmune disorder, biomedical engineering, CAR T-cell therapy, Center for Regenerative Medicine, clinical research, clinical trials, data science, fetal surgery


January 5, 2021

Looking back on 2020: A successful year of research at Mayo Clinic in Florida

By Advancing the Science contributor Advancing the Science contributor

At Mayo Clinic, Research and Education provide the basis for all we are able to do for patients today. Furthermore, they enable practice transformation as we seek to meet future patient needs. From new capabilities in cell therapy and immunotherapy, to advances in neurodegenerative diseases and studies of the virus that causes COVID-19, research at Mayo Clinic continued […]

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Tags: Alzheimer's disease, Ben Pollock, biomanufacturing, biomarkers, biostatistics, brain, cancer, CAR-T, carbon ion therapy, Center for Regenerative Medicine, chemotherapy, clinical research


January 4, 2021

Research News Roundup – Q4 2020

By Elizabeth Zimmermann Elizabeth Zimmermann

The year 2020 was a time during which medical and many other researchers around the world focused much of their attention and effort on a single topic – the SARS-CoV-2 virus and related COVID-19 viral infection. However, other research continued, findings were published, and evidence built for improvements in health outcomes and delivery of health […]

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Tags: antibiotic, artificial intelligence, brain, cancer research, cardiology, cardiovascular medicine, Center for Individualized Medicine, Center for the Science of Health Care Delivery, clinical research, clinical trials, collaboration, coronary artery disease


December 23, 2020

Mayo study shows gene sequencing, translational research improves diagnosis rates

By Colette Gallagher Colette Gallagher

Many patients with unsolved medical mysteries often undergo genetic testing, but the tests do not always provide a conclusive diagnosis. The term “diagnostic odyssey” describes the series of clinical consultations and testing that patients with undiagnosed disorders often receive in search of a genetic diagnosis. To help these patients, Mayo Clinic researchers embarked on a […]

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Tags: Center for Individualized Medicine, clinical research, diagnostic odyssey, Eric Klee, genetic testing, genome, Konstantinos Lazaridis, rare disease


December 2, 2020

Conquering cancer by targeting its genetic abnormalities

By Susan Murphy Susan Murphy

Joanne Garnett has harrowing memories of that life-changing day back in 1981. She was a 39-year-old land use planner living in Wyoming when she received a call from her doctor confirming she had uterine cancer.  “I was shocked, and it was strange because I didn’t fit any profile for uterine cancer,” Garnett recalls. “I got a […]

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Tags: BRCA2, breast cancer, cancer genomics, Center for Individualized Medicine, clinical research, DNA, gene mutation, genetic testing, hereditary cancer, Lynch syndrome, Mayo Clinic Cancer Center, Niloy "Jewel" Samadder


November 23, 2020

Mayo Clinic Research in the news — 11/23/2020

By Elizabeth Zimmermann Elizabeth Zimmermann

There were all sorts of different things in the news this week, but perhaps the most heartening was the news from Dr. Anthony Fauci and our own Gregory Poland, M.D., that Santa Claus and the elves are practicing safe behaviors and COVID-19 won’t stop Christmas from arriving.  Read on for excerpts from this and other […]

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Tags: Amir Lerman, Andrew Badley, Anna Subramaniam, antibiotic, antibodies, anxiety, autism, cardiovascular medicine, clinical research, COVID-19, depression, DNA


November 12, 2020

New research shows markers in donor kidneys that could reduce risks

By Advancing the Science contributor Advancing the Science contributor

By Jay Furst The donation of a kidney to a person in need of a transplant is one of the most profound gifts a person can offer. The process for living kidney donors is safe, and, at Mayo Clinic, which has one of the largest living-donor kidney transplant programs in the U.S., the process is […]

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Tags: Andrew Rule, biopsy, Center for Clinical and Translational Science, clinical research, kidney disease, kidney transplant, living donor, Massini Merzkani, Mayo Clinic Proceedings, Naim Issa


November 9, 2020

Mayo Clinic Research in the news — 11/9/2020

By Elizabeth Zimmermann Elizabeth Zimmermann

As SARS-CoV-2 spreads throughout the world, COVID-19 has become the subject of almost every conversation. Not surprisingly, the media are actively following developments in research on symptoms, testing, treatment and vaccines. In addition to some of these stories, you’ll find Mayo Clinic research and researchers highlighted across a wide range of topics. We are also […]

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Tags: ALS, Alzheimer's disease, amyotrophic lateral sclerosis, animal model, ASTRO, bone disease, cancer screening, cardiovascular medicine, clinical research, colorectal cancer, COVID-19, David Ahlquist


November 6, 2020

Long-term safety, benefits of stem cell therapy for heart failure

By Susan Buckles Susan Buckles

The largest regenerative medicine clinical trial to date for heart failure finds stem cell therapy is safe over the long term and benefits patients with advanced left ventricular enlargement. This multinational research, co-led by Andre Terzic, M.D., Ph.D., director of Mayo Clinic’s Center for Regenerative Medicine, and published in ESC Heart Failure, offers guidance in […]

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Tags: Andre Terzic, cardiovascular disease, Center for Regenerative Medicine, clinical research, clinical trials, heart failure, stem cell research, stem cell therapy


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