Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘clinical research’

September 2, 2021

Understanding the inner workings of CAR-T therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: CAR-T, Center for Individualized Medicine, Center for Regenerative Medicine, chimeric antigen receptor therapy, clinical research, clinical trials, hematology, immunotherapy, Kah Whye Peng, Reona Sakemura, Saad Kenderian, Stephen Russell


August 16, 2021

The dawning of regenerative neurosurgery

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative neurosurgery is poised to transform care of neurological disorders that previously had little hope for improvement, according to a Mayo Clinic review published in The BMJ. Healing diseases of the central nervous system remains a highly coveted but formidable challenge, Terry Burns, M.D., Ph.D., a neurosurgeon scientist at Mayo Clinic, writes in a synopsis […]

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Tags: amyotrophic lateral sclerosis, Center for Regenerative Medicine, clinical research, clinical trials, neurosurgery, spinal cord injury, Terrence Burns, The BMJ


August 3, 2021

Study shows an integrated clinical pharmacist helped reduce provider burnout

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Already a concern before the COVID-19 pandemic, reduced resiliency and burnout among health care providers has become its own crisis. At Mayo Clinic, a number of multidisciplinary teams are looking at ways to reduce burnout and create opportunities to retain and renew resiliency. One recent study, published in the Journal of the American Board of […]

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Tags: burnout, Center for the Science of Health Care Delivery, clinical research, integrated specialty care, Jay Mitchell, Mayo Clinic Health System, patient experience, pharmacy, physician burnout, primary care


July 21, 2021

Mayo researchers develop algorithm to predict rheumatoid arthritis disease activity

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine and Division of Rheumatology have developed a first-of-its-kind machine learning algorithm that can predict rheumatoid arthritis disease activity in a patient. The algorithm analyzes biochemical metabolites ― the product of the body’s metabolism ― in blood. “Having fast, reliable and scalable measures for predicting the clinical course of disease […]

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Tags: arthritis, artificial intelligence, autoimmune disorder, biomarkers, Center for Individualized Medicine, clinical research, genomics, Jaeyun Sung, John Davis III, metabolism, metabolomics, rheumatology


July 14, 2021

Mayo Clinic research in the news — 7/12/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Research and expertise from Mayo Clinic have been in the news on topics from marijuana, sleep, disparities, dementia and doses of vaccine. Read more. New York Times, Can Marijuana Make You a Better Athlete?  … “If you look at any test of physical performance, there’s either no data, it’s a wash, or marijuana makes it worse,” […]

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Tags: addiction research, alcoholism, Alejandro Rabinstein, Alyx Porter, Alzheimer's disease, artificial intelligence, autoimmune disorder, Bhanu Kolla, breast cancer, cancer vaccine, cardiology, Center for Individualized Medicine


June 7, 2021

Mayo Clinic Research in the news — 6/7/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Mayo Clinic research and faculty experts are cited by media outlets on a range of topics this week including the newly-approved Alzheimer’s drug (Monday, 6/7/2021), a new treatment for multiple myeloma and another for precocious puberty, as well as remote patient monitoring and other timely topics. Alzheimer’s Drug Poses a Dilemma for the F.D.A.  The […]

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Tags: Alzheimer's disease, autonomic nervous system, cardiovascular medicine, Chia-Chun Chiang, clinical informatics, clinical research, clinical trials, COVID-19, Cris Ross, David Knopman, DeLisa Fairweather, FDA


April 16, 2021

Stewardship in action: Collaborating to conserve energy

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Amanda Holloway, Office of Sustainability, and Brandon Hill, Supply Chain Management At Mayo Clinic, research drives everything we do for patients. Discovery and innovation are at the root of every new treatment and each expansion of our understanding of disease. Better experiences within the health care system for patients, care givers, and health care […]

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Tags: biomedical research, clinical research, clinical trials, collaboration, community engagement, Department of Laboratory Medicine and Pathology, environment, Mayo Clinic Laboratories


March 3, 2021

Mayo Clinic investigators pursue every clue to solve patients’ rare diseases

By Susan Murphy Susan Murphy (@susanmurphy)

When patients’ illnesses are a mystery and their symptoms have defied a diagnosis, they often turn to Mayo Clinic. There a team of genomic-oriented clinicians and researchers within the Center for Individualized Medicine pursue every possible clue to solve these complex cases.  As many as 30 million Americans have a rare disease. Many patients search […]

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Tags: biobank, biomarkers, Center for Individualized Medicine, clinical research, DNA, Filippo Pinto e Vairo, gene mutation, genetic counseling, genetic testing, genomics, Konstantinos Lazaridis, rare disease


March 1, 2021

Mayo Clinic Research in the news — 3/1/2021

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Media coverage of Mayo Clinic research and expertise covered home cancer screening tests, youth vaping, several advancements in women’s health, COVID-19 and many other topics. Read on for excerpts and links to the articles. Health officials: “Youth vaping a serious issue”  KAAL, 2/25/2021 New findings show youth vaping in Minnesota is worse than many had […]

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Tags: addiction research, Alzheimer's disease, Aminah Jatoi, anaphylaxis, arthritis, basic science, bladder cancer, BRCA1, BRCA2, cancer screening, clinical research, cognitive impairment


February 18, 2021

Advances in sports medicine emerging from Mayo Clinic Health System and collaborators

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The year 2020 offered more research challenges than normal. Many researchers shifted their focus almost entirely to SARS-CoV-2 and COVID-19 – looking for ways to detect, treat and prevent infection, while some projects were forced to take a backseat until conditions improved. Others found the time they needed to move their non COVID-related studies along, […]

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Tags: Andrew Jagim, clinical research, IBD, inflammatory bowel disease, integrative medicine, Jacob Erickson, Joseph Behn, Mayo Clinic Health System, medical research, medical research education, physiology, research


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