Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘clinical trials’

September 21, 2022

Maintaining quality care for patients with ALS — Lessons from the pandemic

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

By Susan Barber Lindquist The efficiency and effectiveness of telemedicine exploded during the COVID-19 pandemic. For patients with Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis or ALS, telemedicine always has been an important piece of their medical care. A recent study in Neurology by Mayo Clinic researchers offers one more proof point. Tests […]

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Tags: ALS, amyotrophic lateral sclerosis, clinical trials, COVID-19, Lou Gehrig's disease, Nathan Staff, neurology, remote patient monitoring, telehealth, telemedicine


August 16, 2022

Addressing diversity barriers to regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

With the promise of regenerative medicine comes the risk of widening health care disparities. Sometimes the newest discoveries, such as regenerative interventions, are out of reach for people in diverse ethnic or socioeconomic groups — or they may not understand or trust new options for healing. Mayo Clinic is trying to overcome those barriers by […]

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Tags: biomedical ethics, Center for Regenerative Medicine, clinical trials, diversity, equity and inclusion, Jorge Mallea, Zubin Master


July 27, 2022

Big data dive confirms early intervention nets better outcomes for people with new onset AFib

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Recent research led by Mayo Clinic showed the findings of the international clinical trial — Early Treatment of Atrial Fibrillation for Stroke Prevention Trial, or EAST‐AFNET 4 — are generalizable to routine clinical practice. The new findings are published online in the Journal of the American Heart Association. The original clinical trial included 2,789 patients […]

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Tags: AFib, atrial fibrillation, big data, cardiovascular medicine, Center for the Science of Health Care Delivery, clinical trials, collaboration, Douglas Packer, EKG, electrocardiogram, health sciences research, Kern Health Care Delivery Scholars


June 15, 2022

Research News Roundup — May 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In May, researchers from Mayo Clinic reported gains in understanding of the benefit of AI-enabled ECGs, including from wearable devices. They made strides towards more effective treatment of non-Hodgkin lymphoma and nonmetastatic gastroesophageal cancer. And in news many people can use, investigators report on the results of a survey linked to the Mayo Clinic Diet. […]

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Tags: AFib, artificial intelligence, atrial fibrillation, CAR-T cell therapy, Center for the Science of Health Care Delivery, clinical trials, cognitive impairment, EKG, electrocardiogram, esophageal cancer, gastric cancer, gastroesophageal cancer


June 14, 2022

Dawn’s journey: Overcoming a near-zero survival rate

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Dawn Botsford was sitting in a chair at the hair salon in the fall of 2011 when her hairdresser commented on a spot on the top of her head. It was bug season in North Dakota, so Dawn didn’t think much of it. “When I told my hairdresser that, she said, ‘I really think you […]

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Tags: cancer, clinical trials, dermatology, Eric Moore, immunotherapy, Mayo Clinic Cancer Center, melanoma, oncology, Robert McWilliams, skin cancer, Stephen Cassivi, Svetomir Markovic


June 3, 2022

Mayo Clinic’s health care delivery scientific expertise exhibited at AcademyHealth’s Annual Research Meeting

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Mayo Clinic research will be on display at the AcademyHealth Annual Research Meeting, June 4 – 7, in Washington, D.C. For people attending the conference, you are invited to stop by the booth, staffed by the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery. In the double […]

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Tags: Aaron Spaulding, AcademyHealth, Ahmed (Shafii) Mohamed, Alanna Chamberlain, artificial intelligence, Ben Pollock, Bridget Biggs, burnout, cardiovascular medicine, Center for the Science of Health Care Delivery, clinical trials, community engagement


May 3, 2022

Research News Roundup — April 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

At Mayo Clinic, biomedical, clinical and health care delivery research are ongoing. The evidence gathered by Mayo researchers, and other scientists, is used to ensure that patients receive the highest quality of care and achieve the best possible outcomes. Advancing the Science’s Research News Roundup excerpts research-related news releases published in the last month. Read […]

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Tags: biomarkers, brain, cancer, cancer prevention, CAR-T cell therapy, Center for Individualized Medicine, clinical trials, colorectal cancer, dementia, diversity, health equity, kidney transplant


April 11, 2022

Unleashing the body’s ability to heal

By Susan Buckles Susan Buckles (@susanbuckles)

“We are the patient’s last, best hope,” has been the motto of the Immune, Progenitor and Cell Therapeutics lab, also known as the IMPACT lab, at Mayo Clinic. This lab specializes in clinical and investigative use of cells as living drugs within the body to fight disease and initiate healing when standard therapies don’t work. […]

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Tags: Allan Dietz, CAR-T cell therapy, cellular therapy, Center for Regenerative Medicine, clinical trials, Dennis Gastineau, Franklyn Prendergast, mesenchymal stem cells, perianal fistula, Stanimar Vuk-Pavlovic


April 5, 2022

Mayo Clinic at the Society of Behavioral Medicine #SBM2022 — the urgency of adaptation

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The 43rd Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine is April 6-9, in Baltimore. With the meeting theme “The Urgency of Adaptation,” the 2022 conference seeks to showcase opportunities for behavioral medicine to increase its effect on the climate crisis, systemic racism, and the COVID-19 pandemic. Embedded in the clinical practice, […]

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Tags: Ahmed (Shafii) Mohamed, Amelia Barwise, Arizona State University, Bridget Biggs, cancer, cardiovascular disease, Center for Health Equity and Community Engagement Research, Center for the Science of Health Care Delivery, clinical trials, community engagement, COVID-19, diabetes


March 28, 2022

Regenerative Medicine Minnesota awards 5 research grants to Mayo Clinic

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative Medicine Minnesota, a statewide bipartisan initiative, has awarded five grants to Mayo Clinic investigators to advance new therapeutic options for osteoarthritis, liver disease, rotator cuff injuries and neurological birth defects. People in Minnesota and beyond struggle with chronic diseases such as heart disease, arthritis and diabetes, and standard care doesn’t always ease the symptoms. […]

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Tags: Aaron Krych, animal model, cartilage, cellular therapy, Center for Regenerative Medicine, Chunfeng Zhao, clinical trials, Jennifer Westendorf, liver failure, mesenchymal stem cells, minimally invasive procedure, molecular biology


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