Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘clinical trials’

May 3, 2022

Research News Roundup — April 2022

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

At Mayo Clinic, biomedical, clinical and health care delivery research are ongoing. The evidence gathered by Mayo researchers, and other scientists, is used to ensure that patients receive the highest quality of care and achieve the best possible outcomes. Advancing the Science’s Research News Roundup excerpts research-related news releases published in the last month. Read […]

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Tags: biomarkers, brain, cancer, cancer prevention, CAR-T cell therapy, Center for Individualized Medicine, clinical trials, colorectal cancer, dementia, diversity, health equity, kidney transplant


April 11, 2022

Unleashing the body’s ability to heal

By Susan Buckles Susan Buckles (@susanbuckles)

“We are the patient’s last, best hope,” has been the motto of the Immune, Progenitor and Cell Therapeutics lab, also known as the IMPACT lab, at Mayo Clinic. This lab specializes in clinical and investigative use of cells as living drugs within the body to fight disease and initiate healing when standard therapies don’t work. […]

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Tags: Allan Dietz, CAR-T cell therapy, cellular therapy, Center for Regenerative Medicine, clinical trials, Dennis Gastineau, Franklyn Prendergast, mesenchymal stem cells, perianal fistula, Stanimar Vuk-Pavlovic


April 5, 2022

Mayo Clinic at the Society of Behavioral Medicine #SBM2022 — the urgency of adaptation

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

The 43rd Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine is April 6-9, in Baltimore. With the meeting theme “The Urgency of Adaptation,” the 2022 conference seeks to showcase opportunities for behavioral medicine to increase its effect on the climate crisis, systemic racism, and the COVID-19 pandemic. Embedded in the clinical practice, […]

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Tags: Ahmed (Shafii) Mohamed, Amelia Barwise, Arizona State University, Bridget Biggs, cancer, cardiovascular disease, Center for Health Equity and Community Engagement Research, Center for the Science of Health Care Delivery, clinical trials, community engagement, COVID-19, diabetes


March 28, 2022

Regenerative Medicine Minnesota awards 5 research grants to Mayo Clinic

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative Medicine Minnesota, a statewide bipartisan initiative, has awarded five grants to Mayo Clinic investigators to advance new therapeutic options for osteoarthritis, liver disease, rotator cuff injuries and neurological birth defects. People in Minnesota and beyond struggle with chronic diseases such as heart disease, arthritis and diabetes, and standard care doesn’t always ease the symptoms. […]

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Tags: Aaron Krych, animal model, cartilage, cellular therapy, Center for Regenerative Medicine, Chunfeng Zhao, clinical trials, Jennifer Westendorf, liver failure, mesenchymal stem cells, minimally invasive procedure, molecular biology


February 28, 2022

Preparing to deliver next-generation therapeutics

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic is among the academic medical centers on the cusp of biomanufacturing next-generation cell and gene therapies that offer hope of new cures for rare and complex diseases. Biomanufacturing this new era of biologic medicines is much different than manufacturing pharmaceuticals from complex molecules. It requires highly specialized lab infrastructure, new processes and new […]

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Tags: Allan Dietz, biomedical engineering, CAR-T cell therapy, Center for Regenerative Medicine, clinical trials, Michael Gustafson, personalized medicine


February 10, 2022

Advanced Care at Home — Evidence-based practice transformation                                        

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Before the pandemic, Mayo Clinic was exploring ways to help patients get home sooner or avoid hospital admission all together. This work has continued, and one of Mayo’s key initiatives in this arena is the Advanced Care at Home program, currently available in Mayo Clinic Health System in Eau Claire, Wisconsin; and at Mayo Clinic […]

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Tags: Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, clinical trials, Elizabeth Habermann, Mayo Clinic Cancer Center, Mayo Clinic Health System, Mayo Clinic Platform, Michael Maniaci, practice improvement, pragmatic trials, Sean Dowdy, Xiaoxi Yao


December 30, 2021

Research News Roundup — 2021 Q4

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

2021 has been another whirlwind year of COVID-19 related advances, so you might have missed all the other medical and health care delivery findings that have emerged. It would take more time than we both have to recap all the non-COVID-19 news from 2021, but if you read further, you’ll learn about some of Mayo […]

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Tags: arthritis, artificial intelligence, cancer, cancer screening, cardiology, cardiovascular medicine, clinical research, clinical trials, colorectal cancer, diabetes, dialysis, EKG


December 13, 2021

Mayo Clinic furthers health care delivery science and best practices at AcademyHealth’s 14th Annual Conference on the Science of Dissemination and Implementation in Health

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

AcademyHealth and the National Institutes of Health sponsor an annual conference dedicated to bridging the gap between research, practice and policy. Investigators in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, and others at Mayo Clinic, participate in this, and other AcademyHealth scientific conferences each year. […]

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Tags: Aaron Leppin, AcademyHealth, Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, clinical informatics, clinical trials, Jennifer Ridgeway, Jessica Austen, mammogram, Mayo Clinic Cancer Center, patient reported outcomes, Sarah Redmond


December 1, 2021

Boosting access for next-generation biotherapies

By Susan Buckles Susan Buckles (@susanbuckles)

Enhanced access to regenerative treatments is needed so new healing solutions become broadly available in clinical care, according to Mayo Clinic research. Achieving validity, utility and mass customization would help realize the regenerative biotherapeutics potential, a Mayo Clinic study reports in the International Journal of Molecular Sciences. “Emerging individualized biotherapies call for on-demand solutions tailored […]

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Tags: Andre Terzic, cardiopoietic cells, Center for Regenerative Medicine, clinical trials, heart failure, Satsuki Yamada


October 12, 2021

What’s the best treatment for this condition? The Knowledge Synthesis team can help.

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Knowledge synthesis is a key component  of health care delivery research in which all available evidence on a particular topic is summarized through comprehensive literature searches and analyzed using advanced qualitative and quantitative synthesis methods. The Knowledge Synthesis Program in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health […]

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Tags: artificial intelligence, big data, Center for the Science of Health Care Delivery, clinical trials, Evidence-based Practice Center, health technology, Irbaz Riaz, kidney cancer, knowledge synthesis, liver disease, M. Hassan Murad, medical innovation


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