Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘clinical trials’

February 7, 2019

Eva Galanis, M.D.-Bitten by the virotherapy bug

By Advancing the Science contributor advancingthescience

Every day more than 1,600 Americans die from cancer. Most of them have cancer that can’t be cured with traditional methods — surgery, radiation and chemotherapy. The father of Evanthia Galanis, M.D., was one of them. He died in the late 1990s from melanoma when his daughter was a junior faculty member at Mayo Clinic. “My father would have […]

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Tags: basic science, cancer, clinical trials, Eva Galanis, gene therapy, hematology, immunotherapy, Mayo Clinic Cancer Center, measles virus, oncology, SPORE, virotherapy


February 5, 2019

Research News Roundup-January 2019

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from Mayo Clinic in the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Minnesota Partnership awards 5 collaborative research grants Diabetes, stress-induced aging and Alzheimer’s disease, immigration-related obesity, and implantable drug […]

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Tags: artificial intelligence, basic science, biomarkers, cancer, cervical cancer, clinical trials, concussion, heart failure, hockey, James Kirkland, Kathy MacLaughlin, Kogod Center on Aging


February 4, 2019

“Only” a medical student, already advancing the science

By Jon Holten jonholten

Rosalie Sterner is already impressive, concurrently pursuing her M.D. and Ph.D. degrees through Mayo Clinic College of Medicine and Science. However, recently she made additional waves, as the lone medical student to receive the 2018 Outstanding Abstract Achievement Award from the American Society of Hematology. Sterner received this award and presented her work on development […]

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Tags: CAR-T, clinical trials, hematology, immunology, Karen Hedin, lymphoma, Rosalie Sterner, Saad Kenderian


January 2, 2019

Toward clinical trials for one type of ALS

By Kate Ledger k8ledger

When a team of Mayo Clinic researchers discovered in 2011 the genetic repeat mutation known as c9orf72, the finding shed new light on amyotrophic lateral sclerosis (ALS). The mutation, which occurs as a short sequence of code repeated hundreds to thousands of times in the gene, is now known to appear in 40 percent of […]

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Tags: ALS, amyotrophic lateral sclerosis, Björn Oskarsson, clinical trials, Dennis Dickson, Kevin Boylan, Leonard Petrucelli, Lou Gehrig's disease, neurology, neurosciences, Rosa Rademakers, Tania Gendron


December 13, 2018

The sky’s the limit

By Advancing the Science contributor advancingthescience

In 2011, Jared Ausnehmer left his local hospital carrying the weight of an oxygen tank and the worry of what might come next. At age 21, he’d already defied the odds for those born with hypoplastic left heart syndrome, a birth defect in which the left side of the heart is underdeveloped or nonexistent. With […]

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Tags: Andre Terzic, cardiology, Center for Regenerative Medicine, clinical trials, HLHS, hypoplastic left heart syndrome


November 5, 2018

Early-phase Cancer Clinical Trials (Phase I) Available at Mayo Clinic

By Nicole Brudos Ferrara nicoleferrara

The Early Cancer Therapeutics Group at Mayo Clinic offers patients whose cancers haven’t responded to standard chemotherapy or other treatments the opportunity to join an early-phase clinical trial of a potential new treatment. Early-phase clinical trials (phase I) determine safe dosage levels and safe methods of treatment delivery. A phase I clinical trial might be […]

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Tags: cancer, clinical trials, Mayo Clinic Cancer Center


September 11, 2018

Meet Katrina Croghan, Clinical Research Coordinator

By Advancing the Science contributor advancingthescience

Katrina Croghan is clinical research coordinator for Mayo Clinic Cancer Center, assigned to the division of Hematology in Rochester, Minnesota. She began her career in ecology and animal science, but while en route to a related Ph.D., ended up as a supplemental research coordinator because of her knowledge of writing protocols and conducting research. She says: “For a short […]

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Tags: clinical trials, hematology, Katrina Croghan, Mayo Clinic Cancer Center


August 6, 2018

Regenerative medicine in novel fetal therapy program

By Jennifer Schutz jenniferschutz

A life-saving procedure improves fetal lung health and reduces post-natal complications Specialists at Mayo Clinic are pioneering a life-saving procedure as part of a clinical trial for babies with congenital diaphragmatic hernia (CDH). When a baby’s lungs are not adequately developed at birth, severe complications and even death can result. Waiting for the baby to be […]

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Tags: Center for Regenerative Medicine, clinical trials, Denise Klinker, maternal and fetal medicine, Mayo Clinic Proceedings, regenerative medicine, Regenerative Medicine Minnesota, Rodrigo Ruano


July 25, 2018

Advances in lung cancer immunotherapy and management of immune-mediated adverse events

By Advancing the Science contributor advancingthescience

Over the last few years, immunotherapy using immune checkpoint inhibitors targeting programmed cell death receptor 1 (PD-1) or programmed cell death receptor ligand 1 (PD-L1) has revolutionized the therapeutic approach to advanced-stage non-small cell lung cancer and numerous other malignancies. Monotherapy, using the anti-PD-1 antibody pembrolizumab, is now Food and Drug Administration (FDA) approved for […]

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Tags: clinical trials, immunotherapy, lung cancer, Mayo Clinic Cancer Center, measles virus


July 9, 2018

Offering underserved groups access to cutting-edge research

By Kris Schanilec kschanilec

For many patients, clinical trials offer a chance to benefit from promising new treatments that are not available in the doctor’s office. Yet not all people have the same access to these opportunities. Groups such as racial minorities, older individuals, and those with low income are less likely than others to participate in clinical trials, […]

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Tags: biobank, blood cancer, Carmen Radecki Breitkopf, clinical trials, community engagement, Gerardo Colon-Otero, health disparities, hematology, HPV, lymphoma, Mayo Clinic Cancer Center


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