Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘clinical trials’

December 13, 2021

Mayo Clinic furthers health care delivery science and best practices at AcademyHealth’s 14th Annual Conference on the Science of Dissemination and Implementation in Health

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

AcademyHealth and the National Institutes of Health sponsor an annual conference dedicated to bridging the gap between research, practice and policy. Investigators in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, and others at Mayo Clinic, participate in this, and other AcademyHealth scientific conferences each year. […]

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Tags: Aaron Leppin, AcademyHealth, Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, clinical informatics, clinical trials, Jennifer Ridgeway, Jessica Austen, mammogram, Mayo Clinic Cancer Center, patient reported outcomes, Sarah Redmond


December 1, 2021

Boosting access for next-generation biotherapies

By Susan Buckles Susan Buckles (@susanbuckles)

Enhanced access to regenerative treatments is needed so new healing solutions become broadly available in clinical care, according to Mayo Clinic research. Achieving validity, utility and mass customization would help realize the regenerative biotherapeutics potential, a Mayo Clinic study reports in the International Journal of Molecular Sciences. “Emerging individualized biotherapies call for on-demand solutions tailored […]

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Tags: Andre Terzic, cardiopoietic cells, Center for Regenerative Medicine, clinical trials, heart failure, Satsuki Yamada


October 12, 2021

What’s the best treatment for this condition? The Knowledge Synthesis team can help.

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Knowledge synthesis is a key component  of health care delivery research in which all available evidence on a particular topic is summarized through comprehensive literature searches and analyzed using advanced qualitative and quantitative synthesis methods. The Knowledge Synthesis Program in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health […]

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Tags: artificial intelligence, big data, Center for the Science of Health Care Delivery, clinical trials, Evidence-based Practice Center, health technology, Irbaz Riaz, kidney cancer, knowledge synthesis, liver disease, M. Hassan Murad, medical innovation


September 28, 2021

Q&A with Dr. Limper, the outgoing Robert D. and Patricia E. Kern Associate Dean of Practice Transformation

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Andrew Limper, M.D., was the first named associate dean of Practice Transformation, in the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery. During his tenure with the center, and through his leadership, Mayo Clinic streamlined practice transformative research and discovery efforts across the institution into a single, […]

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Tags: Andrew Limper, artificial intelligence, basic science, Ben Pollock, biostatistics, cardiology, Center for Clinical and Translational Science, Center for the Science of Health Care Delivery, clinical trials, Curt Storlie, discovery research, electrocardiogram


September 2, 2021

Understanding the inner workings of CAR-T therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: CAR-T cell therapy, Center for Individualized Medicine, Center for Regenerative Medicine, chimeric antigen receptor therapy, clinical research, clinical trials, hematology, immunotherapy, Kah Whye Peng, Reona Sakemura, Saad Kenderian, Stephen Russell


August 23, 2021

Mayo Clinic Research in the news — 8/23/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

In the last 15 days or so, COVID-19 related news continues to dominate the headlines on the research front. However, Mayo Clinic’s expertise also was evident on topics from inclusivity in clinical trials, a geological connection in kidney stones, life extending therapies and better understanding of contributors to dementia, stroke and death. Read on for […]

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Tags: brain, clinical trials, cognitive impairment, COVID-19, dementia, diversity, health disparities, hypertension, idiopathic pulmonary fibrosis, immune system, kidney stones, knee replacement


August 16, 2021

The dawning of regenerative neurosurgery

By Susan Buckles Susan Buckles (@susanbuckles)

Regenerative neurosurgery is poised to transform care of neurological disorders that previously had little hope for improvement, according to a Mayo Clinic review published in The BMJ. Healing diseases of the central nervous system remains a highly coveted but formidable challenge, Terry Burns, M.D., Ph.D., a neurosurgeon scientist at Mayo Clinic, writes in a synopsis […]

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Tags: amyotrophic lateral sclerosis, Center for Regenerative Medicine, clinical research, clinical trials, neurosurgery, spinal cord injury, Terrence Burns


July 19, 2021

Mayo Clinic Research in the news — 7/19/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Mayo research and faculty expertise were cited on topics such as the health benefits of a pet, narcolepsy, the benefits of second opinions for patient outcomes, hiccups, COVID-19 modeling and a variety of other healthcare concerns. Star Tribune, Competing models at start of pandemic hurt public’s trust … Mayo leaders in spring 2020 reached out […]

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Tags: Abinash Virk, aging, Alzheimer's disease, Andrew Badley, Andrew Jagim, anemia, animal model, antiplatelet, anxiety, artificial intelligence, bioethics, biomedical ethics


July 14, 2021

Mayo Clinic research in the news — 7/12/2021

By Advancing the Science contributor Advancing the Science contributor (@advancingthescience)

Research and expertise from Mayo Clinic have been in the news on topics from marijuana, sleep, disparities, dementia and doses of vaccine. Read more. New York Times, Can Marijuana Make You a Better Athlete?  … “If you look at any test of physical performance, there’s either no data, it’s a wash, or marijuana makes it worse,” […]

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Tags: addiction research, alcoholism, Alejandro Rabinstein, Alyx Porter, Alzheimer's disease, artificial intelligence, autoimmune disorder, Bhanu Kolla, breast cancer, cancer vaccine, cardiology, Center for Individualized Medicine


June 17, 2021

Regenerative pipeline for spinal cord repair

By Sara Tiner Sara Tiner (@saratiner)

Mayo Clinic researchers are learning how stem cell therapy can treat neurodegenerative diseases. Mayo is among the first to study whether stem cell therapy might trigger healing for spinal cord injury. Research is ongoing in preclinical models, but it also has advanced from discovery science to early clinical trials. It’s a complex question, because different […]

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Tags: animal model, Ansh Goyal, Anthony Windebank, Bingkun Chen, Center for Regenerative Medicine, clinical trials, F. M. Moinuddin, medical research, mesenchymal stem cells, Mohamad Bydon, Mohammed Ali Alvi, spinal cord injury


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