Items Tagged ‘DNA’
August 25, 2021
Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome
Mayo Clinic researchers published a comprehensive analysis of the gut virome in Gastroenterology, showing how disease, diet and genomics interact with the gut virome in irritable bowel syndrome. This common disorder affects the intestine and manifests as abdominal pain associated with constipation, diarrhea or both. The gut virome is one component of the microbiome (bacteria, fungi, viruses). […]
Tags: Center for Individualized Medicine, DNA, gastroenterology, genomics, gut health, IBS, irritable bowel syndrome, microbiome, Purna Kashyap
March 10, 2021
Mayo Clinic physician cracks patient’s mysterious illness with epigenetics technology
By Susan Murphy 
Kenneth Hobby assumed his fever, fatigue and aching pains on that day in May 2018 were from another bout of malaria. He was visiting Zambia in southern Africa — the stomping grounds of his childhood and a place where the mosquito-borne parasite is common. He had returned to the vast safari lands, as he often […]
Tags: blood disease, Center for Individualized Medicine, DNA, epigenetics, genomics, hematology, Mrinal Patnaik, rare disease
March 3, 2021
Mayo Clinic investigators pursue every clue to solve patients’ rare diseases
By Susan Murphy
When patients’ illnesses are a mystery and their symptoms have defied a diagnosis, they often turn to Mayo Clinic. There a team of genomic-oriented clinicians and researchers within the Center for Individualized Medicine pursue every possible clue to solve these complex cases. As many as 30 million Americans have a rare disease. Many patients search […]
Tags: biobank, biomarkers, Center for Individualized Medicine, clinical research, DNA, Filippo Pinto e Vairo, gene mutation, genetic counseling, genetic testing, genomics, Konstantinos Lazaridis, rare disease
December 9, 2020
Diversifying genomic medicine beyond genes
The work to improve health and health care is ongoing and ever-evolving. It takes many shapes, from streamlining delivery to improving care and pursuing inclusive medical research to help develop precision medicine for all populations. This was a key element of the Arizona Return of Actionable Variants Empirical, or RAVE, study, which brought genomic medicine to […]
Tags: biomedical ethics, Center for Individualized Medicine, clinical trials, diversity, DNA, genetics, genomics, health disparities, Iftikhar Kullo, Richard Sharp
December 2, 2020
Conquering cancer by targeting its genetic abnormalities
By Susan Murphy
Joanne Garnett has harrowing memories of that life-changing day back in 1981. She was a 39-year-old land use planner living in Wyoming when she received a call from her doctor confirming she had uterine cancer. “I was shocked, and it was strange because I didn’t fit any profile for uterine cancer,” Garnett recalls. “I got a […]
Tags: BRCA2, breast cancer, cancer genomics, Center for Individualized Medicine, clinical research, DNA, gene mutation, genetic testing, hereditary cancer, Lynch syndrome, Mayo Clinic Cancer Center, Niloy "Jewel" Samadder
November 23, 2020
Mayo Clinic Research in the news — 11/23/2020
There were all sorts of different things in the news this week, but perhaps the most heartening was the news from Dr. Anthony Fauci and our own Gregory Poland, M.D., that Santa Claus and the elves are practicing safe behaviors and COVID-19 won’t stop Christmas from arriving. Read on for excerpts from this and other […]
Tags: Amir Lerman, Andrew Badley, Anna Subramaniam, antibiotic, antibodies, anxiety, autism, cardiovascular medicine, clinical research, COVID-19, depression, DNA
November 9, 2020
Mayo Clinic Research in the news — 11/9/2020
As SARS-CoV-2 spreads throughout the world, COVID-19 has become the subject of almost every conversation. Not surprisingly, the media are actively following developments in research on symptoms, testing, treatment and vaccines. In addition to some of these stories, you’ll find Mayo Clinic research and researchers highlighted across a wide range of topics. We are also […]
Tags: ALS, Alzheimer's disease, amyotrophic lateral sclerosis, animal model, bone disease, cancer screening, cardiovascular medicine, clinical research, colorectal cancer, COVID-19, David Ahlquist, dementia
October 29, 2020
Developing solutions for early detection of pancreatic cancer
By Advancing the Science contributor
By Lisa Newkirk Pancreatic cancer is one of the deadliest forms of cancer, but patients who are diagnosed at an early stage can survive five years or longer. A team at Mayo Clinic is developing patient-centered solutions for early detection of pancreatic cancer using artificial intelligence and biomarkers. This year, over 57,000 Americans will be […]
Tags: artificial intelligence, biomarkers, cancer genomics, cancer screening, collaboration, CT, DNA, Gloria Petersen, Mayo Clinic Cancer Center, pancreatic cancer, patient experience, Shounak Majumder
October 15, 2020
The latest on testicular cancer-associated KLHL11 encephalitis
By Advancing the Science contributor
Divyanshu (Div) Dubey, M.B.B.S., a Mayo Clinic physician and researcher, who holds a dual appointment in neurology, and laboratory medicine and pathology, recently led a multi-institutional research study to advance understanding of KLHL11 encephalitis or testicular cancer-associated paraneoplastic encephalitis. Published in JAMA Neurology, the paper builds on the work Dr. Dubey and other members of […]
Tags: antibodies, brain, collaboration, Department of Laboratory Medicine and Pathology, Divyanshu Dubey, DNA, encephalitis, neurology, testicular cancer
May 1, 2020
Non-COVID research in the news, 5/1/2020
By Advancing the Science contributor
Although the week’s coverage has largely consisted of COVID-19 news, closer inspection finds it peppered with Mayo Clinic research on some other topics. We’ve collected a few of the news clips for ease of review. Read on for findings in cancer, deep vein thrombosis and Alzheimer’s disease: cfDNA Assay Shows Predictive Value in Detecting Cancer, […]
Tags: Alzheimer's disease, cancer, cancer genomics, David Thiel, deep vein thrombosis, DNA, Guojun Bu, News of the Week, Rosa Rademakers