Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘DNA’

February 12, 2019

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles susanbuckles

Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]

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Tags: Aaron Mansfield, basic science, cancer, Center for Individualized Medicine, DNA, genomics, George Vasmatzis, immunology, Mayo Clinic Cancer Center, mesothelioma


October 1, 2018

How Bread Yeast and Book Damage Help Clarify Epigenetics

By Sara Tiner saratiner

Genes don’t change, but how they are used by the body can.  That shift in use (which is called epigenetics) can mean the difference between illness and health. To better understand how that happens Mayo researchers are examining how genes are activated (used) and copied. With a recent publication in the journal Science, a team […]

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Tags: basic science, Center for Individualized Medicine, Chuanhe Yu, DNA, epigenetics


August 2, 2018

Research News Roundup-July 2018

By Elizabeth Zimmermann elizabethzimmermann

The Mayo Clinic Research News Roundup includes brief summaries and links to research-related news releases from the past month. It also connects readers to associated resources. Read on for more information from Mayo Clinic Research. Anesthesia, surgery linked to subtle decline in memory and thinking in older adults, Mayo study finds In adults over 70, exposure to general […]

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Tags: aging, Alzheimer's disease, basic science, DNA, genomics, Mayo Clinic Proceedings, Mayo Clinic Study of Aging, neurology, ovarian cancer, precision medicine, Research News Roundup


July 5, 2018

Research News Roundup-June 2018

By Elizabeth Zimmermann elizabethzimmermann

Each month, we publish Mayo Clinic’s Research News Roundup. This article includes brief summaries and links to news releases from the preceding month that discuss some of our latest medical research. It also connects readers to related resources. This month’s Roundup includes a number of findings related pancreatic cancer and other gastrointestinal disorders, as well […]

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Tags: basic science, cancer, Center for Individualized Medicine, constipation, diabetes, DNA, DNA testing, gastroenterology, gene mutation, genetic testing, liver cancer, pancreatic cancer


June 25, 2018

Targeted DNA next-generation sequencing aids the molecular assessment of pancreatic neuroendocrine tumors

By Nicole Brudos Ferrara nicoleferrara

Pancreas neuroendocrine tumors (pNETs) are a collection of rare neoplasms distinct from pancreas ductal adenocarcinoma. Although the molecular profile of pNETs is somewhat unclear, advances in molecular tumor genotyping is one area of research that is advancing the understanding of this disease. In a 2017 article published in Oncotarget, Ferga Gleeson, M.D., M.B., B.Ch., a specialist […]

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Tags: basic science, Center for Individualized Medicine, DNA, Ferga Gleeson, gastroenterology, individualized medicine, pancreatic cancer, precision medicine


April 2, 2018

Mayo scientists discover missing link in DNA damage repair

By bobnellis bobnellis

For years, researchers have known that our genome is protected by a system of detection, evaluation and repair processes that activate any time DNA damage occurs. Upon detection, the damage is assessed, repaired in one way or another, or, if it can’t be repaired the cell is cued to self-destruct. Much of that effort is […]

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Tags: basic science, cancer, DNA, Mayo Clinic Cancer Center, Zhenkun Lou


March 22, 2018

Mayo researchers identify characteristics of colon polyps most likely to progress to cancer

By Nicole Brudos Ferrara nicoleferrara

Researchers at Mayo Clinic are closer to answering the question, why does one colon polyp transform to cancer while another seemingly identical polyp does not? A colon polyp is a small clump of cells that forms on the lining of the colon. While most colon polyps are harmless some can develop into colon cancer, which […]

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Tags: biobank, cancer, colon cancer, DNA, Lisa Boardman, Mayo Clinic Cancer Center


February 13, 2018

4 key things to know about the possibilities, pitfalls of gene editing

By Susan Buckles susanbuckles

ROCHESTER, Minn. — Gene editing has captivated scientists and medical providers with tantalizing visions of wiping out debilitating inherited diseases. Could conditions like Huntington’s disease, for example, be cured by using a tool that acts as a “molecular scissors” to remove and replace disease-causing DNA? Or, would gene editing tempt some to engineer designer babies […]

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Tags: biomedical ethics, Center for Individualized Medicine, DNA, Megan Allyse


November 7, 2017

No moss here – Mayo Clinic research websites rolling along

By Elizabeth Zimmermann elizabethzimmermann

They say that a rolling stone gathers no moss, and at Mayo Clinic, our research and research education programs are always on the move. It’s hard to keep track of all the exciting work being done to help improve health for our patients, or the way they – and patients everywhere – experience health care. […]

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Tags: basic science, Christopher Evans, Dev Mukhopadhyay, DNA, Eva Galanis, gene therapy, Jim Maher, Michael Krowka, nanomedicine, osteoarthritis, transplant


February 19, 2016

Madonna Living Community Series Update: Clinomics – New Frontiers in Patient Care

By Elizabeth Zimmermann elizabethzimmermann

Mayo Clinic’s three transformational centers – the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, the Center for Regenerative Medicine, and the Center for Individualized Medicine collaborate with the Madonna Living Community to offer a bi-monthly speaker series in which Mayo Clinic speakers share their research on topics relevant to both residents and the surrounding community. […]

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Tags: DNA, genome, Madonna Living Communities


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