Items Tagged ‘epigenetics’
March 10, 2021
Mayo Clinic physician cracks patient’s mysterious illness with epigenetics technology
By Susan Murphy 
Kenneth Hobby assumed his fever, fatigue and aching pains on that day in May 2018 were from another bout of malaria. He was visiting Zambia in southern Africa — the stomping grounds of his childhood and a place where the mosquito-borne parasite is common. He had returned to the vast safari lands, as he often […]
Tags: blood disease, Center for Individualized Medicine, DNA, epigenetics, genomics, hematology, Mrinal Patnaik, rare disease
June 29, 2020
Research grants aim to advance regenerative medicine toward the practice
Reprogramming human cells to correct blood disorders such as sickle cell disease, activation of a regenerative pathway to treat liver failure and strategies for skeletal regeneration in patients with brittle bone disease are examples of Mayo Clinic research to be funded through new grants from Regenerative Medicine Minnesota. Regenerative Medicine Minnesota, a statewide bipartisan initiative, […]
Tags: clinical trials, Dan Dragomir-Daescu, David Deyle, epigenetics, liver disease, Martin Rodriguez-Porcel, measles virus, nanomedicine, Patricia Devaux, radiation therapy, Regenerative Medicine Minnesota, Rory Smoot
April 30, 2020
Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention
By Susan Murphy
What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]
Tags: Andrea Mariani, biomarkers, cancer, Center for Individualized Medicine, endometrial cancer, epigenetics, gynecology, Marina Walther-Antonio, Mayo Clinic Cancer Center, microbiome, oncology, robotic technology
February 5, 2020
“I Just Didn’t Understand”: On a Mission to Cure ALS
By Advancing the Science contributor
By Barbara J. Toman For Veronique Belzil, Ph.D., the fight against amyotrophic lateral sclerosis (ALS) is personal. In 2000, while working as a psychologist in Canada, she watched her husband’s uncle succumb to the disease. “The progression was so fast and his condition was so sad,” she says. “I just didn’t understand how this could […]
Tags: ALS, amyotrophic lateral sclerosis, Center for Individualized Medicine, DNA, epigenetics, Lou Gehrig's disease, Veronique Belzil
September 18, 2019
Genomics and computer science intersect to improve patient care
By Advancing the Science contributor
By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]
Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign
October 1, 2018
How Bread Yeast and Book Damage Help Clarify Epigenetics
By Sara Tiner 
Genes don’t change, but how they are used by the body can. That shift in use (which is called epigenetics) can mean the difference between illness and health. To better understand how that happens Mayo researchers are examining how genes are activated (used) and copied. With a recent publication in the journal Science, a team […]
Tags: basic science, Center for Individualized Medicine, Chuanhe Yu, DNA, epigenetics
August 1, 2018
Mentorship program makes research aspirations a reality
Mrinal Patnaik, M.B.B.S., is a physician in the Department of Hematology at Mayo Clinic with a keen interest in the clinical management of blood cancers. In recent years, however, Dr. Patnaik realized he wanted to develop a deeper understanding of the disease biology of these cancers and the ways that precision genomics could be used […]
Tags: Center for Clinical and Translational Science, Center for Individualized Medicine, education, epigenetics, genomics, hematology, Mrinal Patnaik, research education