Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘epigenetics’

June 29, 2020

Research grants aim to advance regenerative medicine toward the practice

By Susan Buckles Susan Buckles

Reprogramming human cells to correct blood disorders such as sickle cell disease, activation of a regenerative pathway to treat liver failure and strategies for skeletal regeneration in patients with brittle bone disease are examples of Mayo Clinic research to be funded through new grants from Regenerative Medicine Minnesota.  Regenerative Medicine Minnesota, a statewide bipartisan initiative, […]

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Tags: clinical trials, Dan Dragomir-Daescu, David Deyle, epigenetics, liver disease, Martin Rodriguez-Porcel, measles virus, nanomedicine, Patricia Devaux, radiation therapy, Regenerative Medicine Minnesota, Rory Smoot


April 30, 2020

Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention

By Susan Murphy Susan Murphy

What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]

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Tags: Andrea Mariani, biomarkers, cancer, Center for Individualized Medicine, endometrial cancer, epigenetics, gynecology, Marina Walther-Antonio, Mayo Clinic Cancer Center, microbiome, oncology, robotic technology


February 5, 2020

“I Just Didn’t Understand”: On a Mission to Cure ALS

By Advancing the Science contributor Advancing the Science contributor

By Barbara J. Toman For Veronique Belzil, Ph.D., the fight against amyotrophic lateral sclerosis (ALS) is personal. In 2000, while working as a psychologist in Canada, she watched her husband’s uncle succumb to the disease. “The progression was so fast and his condition was so sad,” she says. “I just didn’t understand how this could […]

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Tags: ALS, amyotrophic lateral sclerosis, Center for Individualized Medicine, DNA, epigenetics, Lou Gehrig's disease, Veronique Belzil


September 18, 2019

Genomics and computer science intersect to improve patient care

By Advancing the Science contributor Advancing the Science contributor

By Sharon Rosen Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive course […]

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Tags: Center for Individualized Medicine, education, epigenetics, genomics, Justin Nguyen, Nidhi Jalan Sakrikar, research education, Timothy Curry, University of Illinois Urbana-Champaign


October 1, 2018

How Bread Yeast and Book Damage Help Clarify Epigenetics

By Sara Tiner Sara Tiner

Genes don’t change, but how they are used by the body can.  That shift in use (which is called epigenetics) can mean the difference between illness and health. To better understand how that happens Mayo researchers are examining how genes are activated (used) and copied. With a recent publication in the journal Science, a team […]

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Tags: basic science, Center for Individualized Medicine, Chuanhe Yu, DNA, epigenetics


August 1, 2018

Mentorship program makes research aspirations a reality

By Caitlin Doran Caitlin Doran

Mrinal Patnaik, M.B.B.S., is a physician in the Department of Hematology at Mayo Clinic with a keen interest in the clinical management of blood cancers. In recent years, however, Dr. Patnaik realized he wanted to develop a deeper understanding of the disease biology of these cancers and the ways that precision genomics could be used […]

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Tags: Center for Clinical and Translational Science, Center for Individualized Medicine, education, epigenetics, genomics, hematology, Mrinal Patnaik, research education


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