Advancing the Science

Mayo Clinic Medical Science Blog – an eclectic collection of research- and research education-related stories: feature stories, mini news bites, learning opportunities, profiles and more from Mayo Clinic.

Items Tagged ‘Forefront’

February 28, 2017

More women eligible for Herceptin, benefit uncertain

By Nicole Ferrara Nicole Ferrara (@nicoleferrara)

Updated guidelines underscore need to identify the most optimal candidates for HER2-directed therapy. Changes to HER2 testing guidelines for breast cancer in 2013 significantly increased the number of patients who test positive for HER2 breast cancer, Mayo Clinic researchers have found. The researchers published their HER2 breast cancer study results online July 25, 2016, in […]

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Tags: breast cancer, Forefront, Mayo Clinic Cancer Center


February 16, 2017

Drug combo safe for diffuse large B-cell lymphoma

By Nicole Ferrara Nicole Ferrara (@nicoleferrara)

  Drugs targeting the P13K-mTOR pathway add benefit when combined with standard R-CHOP therapy.   The drug everolimus can be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma, according to the results of a pilot study by Mayo Clinic researchers. The researchers published their study findings in the July 2016 issue of […]

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Tags: cancer, clinical trials, Forefront, hematology, lymphoma, Mayo Clinic Cancer Center, non-Hodgkin lymphoma, Patrick Johnston


February 5, 2017

Researchers identify unique breast microbiome

By Nicole Ferrara Nicole Ferrara (@nicoleferrara)

A team of Mayo Clinic researchers has identified evidence of bacteria in breast tissue and found differences between women with and without breast cancer. These research findings were published in the August 3, 2016, issue of Scientific Reports. “Our research found that breast tissue samples obtained in the operating room under sterile conditions contain bacterial […]

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Tags: breast cancer, Forefront, Mayo Clinic Cancer Center, microbiome


January 17, 2017

Avoid routine double mastectomy when possible

By Nicole Ferrara Nicole Ferrara (@nicoleferrara)

Consensus group urges weighing pros, cons and patient preference in unilateral breast cancer. A position paper issued by the American Society of Breast Surgeons recommends against contralateral prophylactic mastectomy (CPM) for average-risk women with breast cancer in only one breast. The recommendation on prophylactic mastectomy, published online July 28, 2016, in the Annals of Surgical […]

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Tags: breast cancer, Center for the Science of Health Care Delivery, Forefront, Judy Boughey, Mayo Clinic Cancer Center, Office of Health Disparities Research, women's health


January 10, 2017

Meet the Investigator: Jamie N. Bakkum-Gamez, M.D.

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

At the Mayo Clinic Cancer Center, hundreds of researchers dedicate their professional lives to reducing the burden of cancer. Each one has a unique story. In this issue, Jamie N. Bakkum-Gamez, M.D., a gynecologic oncologist at Mayo Clinic in Rochester, Minnesota, discusses her research. https://youtu.be/mjbfnmFnjIs This is one of a series of Meet the Investigator […]

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Tags: Forefront, Mayo Clinic Cancer Center


January 5, 2017

Stool DNA test added to colorectal screening

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Updated guidelines make noninvasive colorectal cancer screening option available to millions.   The U.S. Preventive Services Task Force has issued its final colorectal cancer screening recommendations for 2016. The task force assigns an overall “A” grade to colorectal cancer screening in people ages 50 to 75 and fully recommends several screening exams that now include […]

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Tags: colon cancer, Forefront


December 29, 2016

Drug combo stems tumor growth in lung cancer

By Nicole Ferrara Nicole Ferrara (@nicoleferrara)

Researchers on Mayo Clinic’s campus in Jacksonville, Florida, have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent. The combination therapy worked in a laboratory study to stop lung adenocarcinoma associated with mutation of the KRAS gene. The study […]

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Tags: chemotherapy, Forefront, lung cancer


December 13, 2016

Nipple-sparing mastectomy may be a good option

By Nicole Ferrara Nicole Ferrara (@nicoleferrara)

Technique offers a safe way to reduce breast cancer risk in carriers of the BRCA mutation. Mastectomies that preserve the nipple and surrounding skin prevent breast cancer as effectively as do more-invasive surgeries for women with a genetic mutation called BRCA, a multi-institution study led by Mayo Clinic Cancer CenterĀ found. The study findings were presented […]

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Tags: breast cancer, Forefront, Mayo Clinic Cancer Center


October 4, 2016

Prostate biopsies down, complications up

By Elizabeth Zimmermann Elizabeth Zimmermann (@elizabethzimmermann)

Researchers are seeking ways to make prostate cancer biopsies safer. While absolute rates of biopsy and post-biopsy complications have decreased after several benchmark prostate-specific antigen (PSA) screening publications, the relative risk for each patient continues to increase, according to a new study by Mayo Clinic researchers. The study is the largest to examine the impact […]

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Tags: Center for the Science of Health Care Delivery, Forefront, Jeffrey Karnes, Mayo Clinic Cancer Center, OptumLabs, prostate cancer, urology


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